Clinical trials: Behavioral Inhibition
Sleep Deprivation
fMRI-behavioral Study of Cholinergic Augmentation With Donepezil in Healthy Sleep Deprived Adults
The purpose of this study was to characterize how the anti-cholinesterase inhibitor (AChE-I) donepezil modulates brain regions involved in visual short-term memory, episodic memory and inhibitory efficiency following 24 hours of…
- Trial name
- NCT00800553
- Testing
- donepezil
- Where
- Singapore
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Duke-NUS Graduate Medical School
Attention Deficit Hyperactivity Disorder (ADHD)
Brain Activity in Adults With ADHD During Neuropsychological Tasks
The aim of the study is to investigate the response on cognitive testing of healthy persons compared to adults with or without medication against ADHD.
- Trial name
- NCT02578342
- Testing
- MRI
- Where
- Switzerland
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Kantonsspital Aarau
Smoking Cessation
The Approach and Avoidance Task (AAT) in Smoking Cessation
The approach and avoidance task (AAT) has evolved as a promising treatment add-on in the realm of psychology. Certain psychiatric diseases, such as behavioural addictions, social anxiety disorder, and arachnophobia, are…
- Trial name
- NCT04190810
- Testing
- Inhibition, Classical AAT, Control
- Where
- Germany
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Cognitive Change, Processing, Visual Spatial
Effects of a Complex, Partnered Martial Arts-based Intervention on Cognitive Function
The investigators' study is designed to test whether brief exposure to a martial arts-based intervention (a coordinative, partnered training exercise known as "Hubod"), can improve cognitive function to a greater degree than…
- Conditions
- Cognitive Change, Processing, Visual Spatial, Inhibition (Psychology), Working Memory
- Trial name
- HUBOD (NCT04760054)
- Testing
- HUBOD, Active Comparator, Control Condition
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Illinois at Urbana-Champaign
Attentional Control Switching, Task Switching Between Modalities
Yoga Practice, Stress and Cognitive Performance
It has been indicated in recent research that Mindfulness-based interventions may offer possibilities of promoting human stress processing and reducing anxiety or depression.
- Conditions
- Attentional Control Switching, Task Switching Between Modalities, Inhibition, Stress
- Trial name
- NCT05232422
- Testing
- Hatha yoga course
- Where
- Austria
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- University of Vienna
Nicotine Addiction, Vaping
Acute Effects of Vaping Nicotine on Cognition in Young Adults
To examine reward processing and cognitive control both with and without the influence of vaporized nicotine in young adults with no history of cigarette use using EEG and fMRI.
- Trial name
- NCT04901208
- Testing
- Nicotine pod
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Yale University
Smoking
Neuroimaging Decision Making and Response Inhibition During Smoking Abstinence
The broad objective of this proposal is to identify functional neuroanatomical correlates of impairments in response inhibition during smoking abstinence.
- Trial name
- SmokeAtt02 (NCT00672256)
- Testing
- Smoking Abstinence
- Where
- United States
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Duke University
Acute Pain, Atrophic
Neurophysiology of Weakness and Exercise in Rotator Cuff Tendinopathy
The purpose of this study is to examine deficits in activation and motor patterns, as well as central drive in patients with rotator cuff tendinopathy.
- Conditions
- Acute Pain, Atrophic, Goals, Impairment
- Trial name
- NCT02971072
- Testing
- Subacromial injection, Physical Therapy
- Where
- United States
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- University of Oregon
Dyspnea, Muscle Strain
Muscle Reflex Inhibition in Hypoxic Exercise
The goal of this interventional study is to compare muscle reflex function under settings of normoxia (normal oxygen level), acute hypoxia (brief oxygen-lack) and chronic hypoxia (long-duration exposure to oxygen-lack).
- Trial name
- NCT05619887
- Testing
- Fentanyl, Saline
- Where
- Canada
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Feeding Behavior, Inhibition (Psychology)
Specificity of Flavor-Nutrient Learning: An fMRI Experiment
This is an etiology study designed to examine the how people's brains and behaviors respond to regularly consuming a beverage. Participants are assessed at 2 behavioral assessments (Wave 1 and Wave 2), 2 scans (at the BRIC), and…
- Trial name
- NCT02624206
- Testing
- Juice A, Juice B
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Myocardial Infarction, Arthritis
Mechanisms of Action of Acetaminophen
This research study investigates whether the ability of aspirin to reduce the risk of heart attacks may be diminished by the administration of acetaminophen.
- Trial name
- NCT00646906
- Testing
- Aspirin First, Aspirin Last, Acetaminophen 1000 mg/d
- Where
- United States
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Inhibition
Exploring the Impact of Biofeedback on the Inhibitory Control of Healthy Older Adults
Inhibitory control refers to the conscious and voluntary suppression of predominant responses when they are automatic, inappropriate, or incorrect.
- Trial name
- I-BF (NCT04925830)
- Testing
- Heart rate variability biofeedback; haemoncephalography biofeedback
- Where
- Switzerland
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- University Hospital, Geneva
Physiology
Physiopathology of Lower Cortical Activation in COPD Patients: Contribution of Cortical Neuromodulation
Patients with COPD have lower cortical activation and higher cortical inhibitory levels. The purpose of this study is to test the reversibility the lower cortical activation by counterbalancing the increased cortical inhibitory…
- Trial name
- NCT03368703
- Testing
- Anodal transcranial direct-current-stimulation
- Where
- France
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- 5 Santé
Healthy
Brain Encoding for Memory
This two-part study will use transcranial magnetic stimulation, or TMS (see below), to explore how the brain forms memories. People remember only some of the events they experience every day, such as faces they perceive, words…
- Trial name
- NCT00051870
- Testing
- Magstim Rapid Magnetic Stimulator
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Cognitive Fatigue, Mental Fatigue
Effects of Natural Sounds on Attention Restoration in Noisy Environment
This study aims to examine whether listening to natural sounds in a noisy (traffic) environment compared to traffic noise only impacts behavioural, cognitive, affective, and physiological markers associated with attention…
- Conditions
- Cognitive Fatigue, Mental Fatigue, Heart Rate Variability, Skin Conductance
- Trial name
- EARS (NCT05009784)
- Testing
- Baseline, Fatigue Manipulation, Traffic Sound
- Where
- Singapore
- Volunteers
- 162 people, healthy volunteers welcome
- Sponsor
- Nanyang Technological University
Autism, ADHD
Five Digits Test - Validation of a Neuropsychological Test of Inhibition for Patients With Neuropsychiatric Conditions
Neuropsychiatric conditions such as Attention Deficit Hyperactivity Disorder (ADHD) and autism are characterized by specific deficits in cognitive functions.
- Trial name
- NCT07531914
- Testing
- Five Digits Test
- Where
- Sweden
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Umeå University
Mental Fatigue
Mindfulness, Mental Fatigue, Inhibitory Control and Endurance Performance in Athletes
This study investigated whether trait mindfulness in athletes is associated with impairments in neurocognitive function and endurance performance resulting from mental fatigue.
- Trial name
- NCT05466136
- Testing
- Mental fatigue condition, Control condition
- Where
- Taiwan
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- National Taiwan Normal University
Attention Deficit Hyperactivity Disorder (ADHD)
Integrated Brain, Body and Social Intervention for Attention Deficit Hyperactivity Disorder (ADHD)
The investigators are conducting this randomized trial to determine if IBBS (Integrated Brain, Body, and Social)intervention is an effective treatment for ADHD (attention Deficit Hyperactivity Disorder) in two culturally distinct…
- Trial name
- IBBS (NCT01542528)
- Testing
- IBBS
- Where
- 5 sites in United States, China
- Volunteers
- 117 people, healthy volunteers welcome
- Sponsor
- Yale University
Tobacco Use Disorder, Smoking
Low Dose Aspirin Inhibition of COX-2 Derived PGE2 in Male Smokers
Regular aspirin use has been associated with a reduction in the development of a number of different malignancies including lung cancer. The mechanism of aspirin's cancer prevention is not known.
- Trial name
- NCT01796951
- Testing
- Aspirin 325 mg daily, Celecoxib 200 mg BID
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University
Healthy, Adolescent
Physical Activity on Motor Competence, Cognitive Function and Mood in Adolescents
The study aimed to determine the effect of coordinative-based physical activity practices on motor competence, cognitive function and mood levels of adolescent boys.
- Trial name
- NCT07111780
- Testing
- "Coordinative-Based Physical Activity Practices" training group
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Namik Kemal University