Clinical trials: Behavioral Modification
Obesity, Childhood, Pediatric Obesity
Treatment Efforts Addressing Child Weight Management by Unifying Patients, Parents & Providers
The US Preventive Services Task Force (USPSTF) recommends that providers screen children aged 6 years and older for obesity and offer or refer them to a comprehensive behavioral intervention (≥26 hours over a period of up to 12…
- Conditions
- Obesity, Childhood, Pediatric Obesity, Childhood Obesity, Adolescent Obesity
- Trial name
- TEAM UP (NCT03843424)
- Testing
- eSOC program, FBT program
- Where
- 7 sites in United States
- Volunteers
- 1,460 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Obesity, Lifestyle, Healthy
Twelve-year Follow-up on the Treatment of Obese Pregnant Women (TOP) Study
The participant (both mother and child) in the initial TOP study will be invited to a follow-up study to evaluate the effect of life style intervention during pregnancy on both mother and their offspring 12 years after the…
- Conditions
- Obesity, Lifestyle, Healthy, Diet, Healthy, Follow-up
- Trial name
- TOP12 (NCT05446220)
- Testing
- Lifestyle intervention
- Where
- Denmark
- Volunteers
- 497 people, healthy volunteers welcome
- Sponsor
- Steno Diabetes Center Copenhagen
Tobacco Use
A Study to Evaluate Changes in Smokers Using Oral Tobacco-derived Nicotine Products.
The purpose of this study is to evaluate changes in exposure to selected harmful and potentially harmful constituents (HPHC) by measuring biomarkers in adult smokers who partially or completely switch from smoking cigarettes to…
- Trial name
- NCT03692078
- Testing
- OTDN product 1, OTDN product 2, Tobacco Cessation
- Where
- 2 sites in United States
- Volunteers
- 231 people, healthy volunteers welcome
- Sponsor
- Altria Client Services LLC
Nicotine Dependence
IV Nicotine Induced Changes in Hormone Function, Mood States and Behavior
Clinical studies are proposed to analyze the interactions between nicotine, alterations in endocrine hormones, mood and cardiovascular measures.
- Trial name
- NCT01589055
- Testing
- Intravenous Nicotine
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Mclean Hospital
Caregiver Distress
Reducing Distress in Phase 1 Trial Caregivers: The P1-CaLL Study
This study seeks to decrease distress in the lives of the caregivers who are helping cancer patients who have entered a phase 1 clinical trial.
- Trial name
- NCT03557515
- Testing
- Stress Management and CBT, Stress Management and Metta-Meditation
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Prediabetic State
A Study of Attitudes About the Risk of Developing Type 2 Diabetes
Diabetes mellitus (DM) type 2 is well recognized as a major cause of morbidity and mortality in the United States, as well as a significant contributor to health disparities within the population.
- Trial name
- NCT00323349
- Testing
- Oral Glucose Tolerance Testing, Education tailored to learning style preferences
- Where
- 2 sites in United States
- Volunteers
- 276 people, healthy volunteers welcome
- Sponsor
- Eastern Virginia Medical School
Behavior Therapy
Therapy Labs: To Improve Adherence in Internet Based Psychotherapy
This project aims to investigate factors that are important in affecting adherence in internet based Cognitive Behavior Therapy (CBT).
- Trial name
- NCT02535598
- Testing
- Normal presentation, Enhanced presentation, Normal support
- Where
- Sweden
- Volunteers
- 169 people, healthy volunteers welcome
- Sponsor
- Uppsala University
Obsessive-Compulsive Disorder
Effect of Cognitive Behavioral Therapy in OCD Highlighted by Neuropsychological Tests and MRI: Pathophysiology and Treatment Outcome Predictors
OCD patients are assessed before and after treatment using diagnostic tools, rating scales neuropsychological assessment and functional and structural MR-scans.
- Trial name
- NCT00792038
- Where
- Denmark
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Obesity, Weight Loss
Attitudes Toward Food During a Weight Loss Intervention
The purpose of this study is to evaluate whether the Noom Healthy Weight Program, a digital behavior change weight loss intervention, creates a positive relationship with food, compared to a waitlist control group.
- Conditions
- Obesity, Weight Loss, Overweight and Obesity, Overweight or Obesity
- Trial name
- NCT04586647
- Testing
- Noom Healthy Weight; mobile behavior change program for weight loss.
- Where
- United States
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Noom Inc.
Prediabetes, Weight Loss
Diabetes Prevention Through Genetics, Familial History and Behavior Change
The goal of this clinical trial is to learn if adding a family engagement component to the standard Diabetes Prevention Program (DPP) improves outcomes for adults with prediabetes.
- Trial name
- NCT07815236
- Testing
- LEGACY DPP, DPP
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Morehouse School of Medicine
Dementia, Alzheimer Disease
Small Steps Towards Improving Activity and Sleep Habits to Decrease the Risk of Dementia
This is a randomised controlled study aiming to evaluate the implementation of a website ('Small Steps') to support the modification of participants' time-use behaviour to reduce the risk factors for dementia.
- Trial name
- NCT06291909
- Testing
- Small Steps Program, Comparator Program
- Where
- Australia
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- University of South Australia
Climate Anxiety, Menstrual Product Choice
ECOLOGICAL MESSAGE FRAMING AND SUSTAINABLE MENSTRUAL PRODUCT CHOICES
Background: Climate change is an increasing public health concern, with growing evidence linking climate change anxiety to health behaviors.
- Conditions
- Climate Anxiety, Menstrual Product Choice, Environmental Sustainability, Health Behavior
- Trial name
- NCT07610421
- Testing
- Gain-framed ecological message, Loss-framed ecological message, Neutral informational message
- Where
- Turkey (Türkiye)
- Volunteers
- 246 people, healthy volunteers welcome
- Sponsor
- Ankara Medipol University
Overweight and Obesity, Physical Activity
Understanding Mechanisms of Exercise Behavior Change
This research seeks to examine psychological factors that may impact relationship between incentives and health behavior engagement, specifically physical activity.
- Conditions
- Overweight and Obesity, Physical Activity, Incentives
- Trial name
- NCT03465800
- Testing
- self-monitoring, daily incentives, delayed lump sum incentives
- Where
- United States
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Boulder
Premature Ejaculation
Silicone Band Versus Prilocaine Spray for Lifelong Premature Ejaculation
This pilot study compared two approaches for men with lifelong premature ejaculation, a condition in which ejaculation occurs sooner than desired from the first sexual experiences and is difficult to delay.
- Trial name
- NCT07820865
- Testing
- Frenular Silicone Band, Prilocaine 10% Spray
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Başakşehir Çam & Sakura City Hospital
Obsessive Compulsive Disorder, Autism Spectrum Disorder
Internet Delivered CBT for OCD in Adolescents With ASD - A Clinical Case Series
The aim of this study is to test the feasibility and acceptability of an internet-delivered cognitive behavior therapy (ICBT) intervention originally developed for neurotypical adolescents with obsessive compulsive disorder (OCD)…
- Trial name
- NCT02660099
- Testing
- Internet-delivered Cognitive Behavior Therapy
- Where
- 2 sites in Sweden
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Anxiety
Guided Self-help for Anxiety - a Patient Preference Trial
Supporting patients in exerting choice over their treatment is a central aspect of modern healthcare. In Improving Access to Psychological Therapies (IAPT) services, then patients treated at step 2 are only and always offered…
- Trial name
- NCT03730532
- Testing
- Cognitive Behavioural Therapy Guided Self Help, Cognitive Analytic Therapy Guided Self Help
- Where
- United Kingdom
- Volunteers
- 134 people, healthy volunteers welcome
- Sponsor
- University of Sheffield
Breast Cancer
An Internet-based Weight Loss and Exercise Intervention for Breast Cancer Survivors
The purpose of this study is to test the effectiveness of a behavioral weight loss and exercise intervention delivered via the internet at different cancer centers in New England.
- Trial name
- iWEB (NCT01728506)
- Testing
- Weight Loss and Exercise
- Where
- 3 sites in United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- University of Vermont
Breast Cancer Prevention
MELIORA Virtual Coach Intervention for Breast Cancer Prevention
Breast cancer (BC) is the most commonly diagnosed cancer in women worldwide, with early-onset cases increasing due to genetic and lifestyle factors.
- Trial name
- MELIORA (NCT07200427)
- Testing
- MELIORA Virtual Coach Intervention, Control (generic advice)
- Where
- 7 sites in Greece, Lithuania and 2 more
- Volunteers
- 2,080 people, healthy volunteers welcome
- Sponsor
- Harokopio University
Weight Gain
Effects of Modafinil on Olanzapine Weight Gain
This study is designed as a 3 week, randomized, double blind, placebo controlled, trial. Olanzapine and modafinil will be titrated to 10mg and 200mg respectively.
- Trial name
- NCT00636896
- Testing
- Olanzapine plus modafinil
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Neuropsychiatric Research Institute, Fargo, North Dakota
Prediabetes, Prehypertension
Health Coaching to Effect Lifestyle Behaviour Change
A health coaching intervention in those with pre-disease (pre-hypertension or pre-diabetes) but without pre-existing cardiovascular disease will effectively help participants change their lifestyle behaviour and prevent or delay…
- Trial name
- HC (NCT01458496)
- Testing
- Health Coaching
- Where
- 2 sites in Canada
- Volunteers
- 219 people, healthy volunteers welcome
- Sponsor
- Marshal Godwin
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