Clinical trials: Behavioral Modification
Concussion, Mild
Delivery of Digital Cognitive Behavioural Therapy Following Concussion
Concussion is common and patients can go on to suffer with a constellation of symptoms which impacts their functional outcome and quality of life.
- Trial name
- HEADON (NCT05069948)
- Testing
- HeadOn
- Where
- United Kingdom
- Volunteers
- 50 people
- Sponsor
- University of Edinburgh
Depression
Behavioral Study of Effects of Low-Level Light Therapy on Mood and Reaction Time
The goal of this project is to use low-level light therapy (LLLT) to enhance neural metabolism in the prefrontal cortex of humans, and measure the effects of LLLT on attentional bias change following a single session of attention…
- Trial name
- NCT02390076
- Testing
- Left Low Level Light Therapy, Attention bias modification, Right Low Level Light Therapy
- Volunteers
- 51 people
- Sponsor
- Seth Disner
Cardiovascular Disease, Depression
Internet-guided Cognitive Behavioural Therapy to Improve Depression Patients With Cardiovascular Disease
Purpose and aims Tailored internet-based cognitive behavioural therapy (I-CBT) is a new innovative and person-centred method that is promising that may be used to decrease depression in patients with cardiovascular disease (CVD).
- Trial name
- NCT02778074
- Testing
- Internet cognitive behavioural therapy, Moderated Discussion Forum
- Where
- Sweden
- Volunteers
- 144 people
- Sponsor
- University Hospital, Linkoeping
Pulmonary Tuberculosis, Body Weight Changes
Fermented Soybean Supplementation Among Active Pulmonary Tuberculosis Patients With Standard Therapy in Indonesia
Tuberculosis (TB) patients often have a lower body mass index (BMI) and experience wasting. Wasting reduces lean body mass and may cause physical function impairment.
- Conditions
- Pulmonary Tuberculosis, Body Weight Changes, Motor Activity
- Trial name
- FSS (NCT02554318)
- Testing
- Rifampicin, Isoniazid, Pyrazinamide
- Volunteers
- 147 people
- Sponsor
- University of Giessen
Obsessive-Compulsive Disorder in Children, Social Anxiety Disorder of Childhood
Parent-based Treatment for Youth With Anxiety and Obsessive-compulsive Disorder
Anxiety and obsessive-compulsive disorders are the most common mental health disorders in childhood and adolescence. A parenting intervention for youth with anxiety, called Supportive Parenting of Anxious Childhood Emotions…
- Conditions
- Obsessive-Compulsive Disorder in Children, Social Anxiety Disorder of Childhood, Obsessive-Compulsive Disorder in Adolescence, Separation Anxiety
- Trial name
- NCT04922502
- Testing
- Standard SPACE, Bibliotherapy, low therapist contact SPACE
- Where
- United States
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Baylor College of Medicine
Depressive Symptoms, Stress, Psychological
Mobile Web-based Behavioral Intervention for Improving Caregiver Well-being
Caregivers suffer great amounts of distress that significantly impacts their mental and physical well-being, yet caregivers' access to quality, evidence-based care is currently very limited.
- Trial name
- NCT03506945
- Testing
- mPEP, Bibliotherapy
- Where
- United States
- Volunteers
- 184 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Weight Loss, Obesity
Testing the Effectiveness of WW Clinic GLP1
The study objective is to evaluate the efficacy of the WeightWatchers (WW) GLP-1 behavioral program + WW Clinic (formerly known as Sequence medical weight management program) on weight loss and related outcomes.
- Trial name
- WW Clinic (NCT06034457)
- Where
- United States
- Volunteers
- 180 people
- Sponsor
- The Cleveland Clinic
Tobacco Dependence
Tobacco Dependence Treatment for Asian Americans
Nicotine dependence is very common among Asian Americans; yet, research on understanding and treating nicotine dependence in this group is almost nonexistent.
- Trial name
- NCT01091363
- Testing
- Standard, Deep Cultural
- Where
- United States
- Volunteers
- 109 people, healthy volunteers welcome
- Sponsor
- University of Massachusetts, Boston
Obesity
Use of Medication to Improve Weight Loss in Suboptimal Early Responders to Behavioral Treatment
This is a two-phase study. Phase 1 will evaluate obesity-related behavioral and biological characteristics as potential predictors of response to behavioral treatment (BT) for weight loss.
- Trial name
- NCT03779048
- Testing
- Behavioral Treatment, Phentermine 15 MG
- Where
- United States
- Volunteers
- 147 people
- Sponsor
- University of Pennsylvania
Nicotine Dependence
Trial on the Effectiveness of Mindfulness Training for Smokers
The Mindfulness Training for Smokers study follows a randomized controlled design with 240 total participants. Both the study group and the control group will be enrolled in the Wisconsin Tobacco Quit Line and will receive four…
- Trial name
- MTS (NCT01093599)
- Testing
- Quit Line plus MTS, Quit Line Only
- Where
- United States
- Volunteers
- 196 people
- Sponsor
- University of Wisconsin, Madison
Cigarette Smoking, Nicotine Dependence
Treatment of Smoking Among Individuals With PTSD
This study will examine the effect of combining prolonged exposure, a cognitive-behavioral treatment program for post-traumatic stress disorder (PTSD) with medication (varenicline) and counseling treatments for smoking cessation.
- Conditions
- Cigarette Smoking, Nicotine Dependence, Post-traumatic Stress Disorder, Tobacco Use Disorder
- Trial name
- NCT00937235
- Testing
- Varenicline, Medication Management Counseling, Prolonged Exposure
- Where
- United States
- Volunteers
- 142 people
- Sponsor
- University of Pennsylvania
Hypertension
Reach Out: Emergency Department-Initiated Hypertension Behavioral Intervention Connecting Multiple Health Systems
This study evaluates a health theory based mobile health behavioral intervention to reduce blood pressure (BP) among hypertensive patients evaluated in a community Emergency Department (ED) setting.
- Trial name
- ReachOut ED (NCT03422718)
- Testing
- Healthy Behavior Texts, No healthy behavior texts, BP Monitoring Daily Via Text Messaging
- Where
- United States
- Volunteers
- 488 people
- Sponsor
- University of Michigan
Obesity, Overweight
Does Motivational Interviewing Improve Behavioral Weight Loss Outcomes for Obesity?
The purpose of this study is to determine whether adding motivational interviewing (MI) to a behavioural weight loss program (BWLP) results in improved weight loss for adults who are overweight or obese.
- Trial name
- BWLP+MI (NCT02649634)
- Testing
- Motivational Interviewing, Attention Control
- Volunteers
- 135 people
- Sponsor
- University of Calgary
Sleep Fragmentation, Poor Quality Sleep
Impact of Behavioral Treatment of Insomnia on Nighttime Urine Production
Nocturia is prevalent in older adults and it vastly reduces quality of life. Yet its treatment remains inadequate because its causes are not well understood, especially nocturnal polyuria or increased urine production at night.
- Conditions
- Sleep Fragmentation, Poor Quality Sleep, Nocturia, Nocturnal Enuresis
- Trial name
- NCT03883724
- Testing
- Brief behavioral treatment of insomnia (BBTI), Information-only control (IC)
- Where
- United States
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Conduct Disorder, Oppositional Defiant Disorder
Behavioral Treatment for Children With Conduct Problems and Callous-Unemotional Traits
The purpose of this study is to modify behavior therapy so that it is optimized for children with conduct problems and callous-unemotional traits by emphasizing reward components and de-emphasizing punishment components.
- Trial name
- NCT01362946
- Testing
- Reward-Emphasized Treatment, Standard Treatment
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- Florida International University
Binge Drinking
An Open Label Trial of Bupropion and Naltrexone for Binge Drinking
This is an open-label Phase IIa pilot study of the tolerability and effects on binge drinking of bupropion and naltrexone for binge drinkers.
- Trial name
- NCT02842073
- Testing
- Naltrexone, Bupropion
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- University of North Carolina, Chapel Hill
Posttraumatic Stress Disorder, Depression
A Trial of Group Psychotherapy for Veterans and Military Personnel With Post Traumatic Stress Disorder (PTSD)
The purpose of this study is to test the effectiveness of group psychotherapy designed specifically for male veterans and active-duty personnel with Post-traumatic Stress Disorder (PTSD), Major Depressive Disorder (MDD) and with…
- Conditions
- Posttraumatic Stress Disorder, Depression, Insomnia Disorder
- Trial name
- NCT00984698
- Testing
- Cognitive Behavioral Social Rhythm Group Therapy, Present Centered Group Therapy
- Where
- 2 sites in United States
- Volunteers
- 115 people
- Sponsor
- University of Arizona
Obesity, Overweight
A Study of Tirzepatide (LY3298176) In Participants After A Lifestyle Weight Loss Program
This is a study of tirzepatide in participants with obesity. The purpose of this study is to learn more about how tirzepatide maintains body weight or adds to weight loss after an intensive lifestyle modification program.
- Trial name
- SURMOUNT-3 (NCT04657016)
- Testing
- Tirzepatide
- Where
- 65 sites in United States, Argentina and 2 more
- Volunteers
- 579 people
- Sponsor
- Eli Lilly and Company
Suicide, Psychosis
Cognitive Behavioral Suicide Prevention for Psychosis: Aim 2
Investigators will evaluate the feasibility and preliminary effectiveness of modified Cognitive Behavioral Suicide Prevention for psychosis (CBSPp) in comparison to services-as-usual (SAU) in a randomized controlled trial.
- Trial name
- NCT05345184
- Testing
- Cognitive Behavioral Suicide Prevention for psychosis (CBSPp), Services as Usual (SAU)
- Where
- United States
- Volunteers
- 51 people
- Sponsor
- University of Michigan
Metabolism and Nutrition Disorder, Obesity
Effect and Safety of Liraglutide 3.0 mg as an Adjunct to Intensive Behaviour Therapy for Obesity in a Non-specialist Setting
This trial is conducted in the United States of America (USA). The purpose of the trial is to investigate the effect and safety of liraglutide 3.0 mg as an adjunct to intensive behaviour therapy for obesity in a non-specialist…
- Trial name
- SCALE™ IBT (NCT02963935)
- Testing
- liraglutide, CMS Intensive Behavior Therapy
- Where
- 10 sites in United States
- Volunteers
- 282 people
- Sponsor
- Novo Nordisk A/S