Clinical trials: Behavioral Problems
Hot Flushes, Night Sweats
Progesterone for Perimenopausal Night Sweats
The purpose of this study is to test whether a oral micronized progesterone reduces the Vasomotor Symptom Score comprised of the number and severity of hot flushes and night sweats in perimenopausal women.
- Trial name
- NCT01464697
- Testing
- Oral micronized progesterone
- Where
- Canada
- Volunteers
- 249 people
- Sponsor
- University of British Columbia
Mild Cognitive Impairment, Cognitive Decline
Exercise in Adults With Mild Memory Problems
This study evaluates the effects of physical exercise on cognition, functional status, brain atrophy and blood flow, and cerebrospinal fluid biomarkers of Alzheimer's disease in adults with a mild memory impairment.
- Conditions
- Mild Cognitive Impairment, Cognitive Decline, Memory Impairment
- Trial name
- EXERT (NCT02814526)
- Testing
- Aerobic exercise, Stretching/balance/range of motion exercise
- Where
- 14 sites in United States
- Volunteers
- 296 people
- Sponsor
- Alzheimer's Disease Cooperative Study (ADCS)
Adolescent Alcohol Use
Brief Motivational Interviewing +/- Mindfulness Training for Adolescent Alcohol Use in Pediatric Primary Care
Alcohol use is prevalent in U.S. adolescents and contributes to adverse health outcomes in this population. Care for adolescent alcohol use is lacking in most pediatric primary care settings (PPC).
- Trial name
- PCORIMINDSET (NCT07059078)
- Testing
- Brief Motivational Interviewing-based Alcohol Intervention, Smartphone App-delivered Mindfulness Training
- Where
- 13 sites in United States
- Volunteers
- 1,500 people
- Sponsor
- Johns Hopkins University
Autistic Disorder, Constipation
Impact of Improving Gastrointestinal Symptoms on Autism Symptoms and Oxidative Stress
The clinical manifestation of autism spectrum disorder (ASD) is complex, with medical and mental health disruptions that occur with the three core behavioral criteria used for diagnosis (social behavior, communication, restricted…
- Conditions
- Autistic Disorder, Constipation, Gastrointestinal Diseases
- Trial name
- NCT02442115
- Testing
- Treatment of Functional Constipation by
- Where
- 2 sites in United States
- Volunteers
- 100 people
- Sponsor
- Children's Hospital Los Angeles
Epileptic Children,Sleep Disturbances,Maladaptive Behaviors
Sleep Problems in Epileptic Children and Their Caregivers
The aim of this study is to investigate the frequency of sleep problems in epileptic children and their caregivers.
- Trial name
- NCT05191576
- Testing
- Children's sleep habits questionnaire (CSHQ)
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Ege University
Depression, Cognition Disorders
Therapy for Depressed Elders With Thought Problems
This study will compare the effectiveness of Problem Solving Therapy and Brief Supportive Therapy in treating elderly patients with major depression and thought problems.
- Trial name
- NCT00052091
- Testing
- Problem Solving Therapy, Brief Supportive Therapy
- Where
- 2 sites in United States
- Volunteers
- 221 people
- Sponsor
- University of Washington
Depressive Disorder, Major, Generalized Anxiety Disorder
Student Precarity and Psychiatry
Since the COVID-19 pandemic, mental health disorders have increased significantly, particularly among young people. In France, the proportion of young people aged 18 to 25 suffering from depression almost doubled between 2017 and…
- Conditions
- Depressive Disorder, Major, Generalized Anxiety Disorder, Suicidal Ideation, Loneliness
- Trial name
- PEPSY (NCT07618208)
- Testing
- Questionnaires
- Volunteers
- 45,000 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Intellectual Disability, Developmental Disability
Clinical Trial of Nabilone for Aggression in Adults With Intellectual and Developmental Disabilities
Innovative treatments are urgently needed for severe behavioural problems (SBPs) in adults with intellectual and developmental disabilities (IDD).
- Conditions
- Intellectual Disability, Developmental Disability, Aggression, Behavior Problem
- Trial name
- N-AND (NCT05273320)
- Testing
- Nabilone
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- Hsiang-Yuan Lin
Mental Disorder, Mental Health
Engaging Homeless Youth in Vocational Training to Meet Their Mental Health Needs
This randomized controlled trial (RCT) compared the efficacy between the Social Enterprise Intervention (SEI) and Individual Placement and Support (IPS) with homeless youth with mental illness.
- Conditions
- Mental Disorder, Mental Health, Employment, Housing Problems
- Trial name
- SEI (NCT03118388)
- Testing
- Social Enterprise Intervention, IPS
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Arizona State University
Adverse Childhood Experiences, Housing Problems
Evaluation of the Building Healthy Life Skills Program
The goal of this intervention trial is to learn test whether participation in the Building Health Life Skills Program leads to improvements in psychological well-being and stress management skills for people who are experiencing…
- Conditions
- Adverse Childhood Experiences, Housing Problems, Emotion Regulation
- Trial name
- NCT05611060
- Testing
- Building Healthy Life Skills Program
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of California, Merced
Insomnia
Examining the Effectiveness of Two Behavioral Interventions for Sleep Problems in Infants
Behavioral insomnia of childhood affects 15-30% of infants. Behavioral interventions, based on limiting parent-child bedtime and nighttime interactions, are effective in significantly improving infant sleep problems.
- Trial name
- NCT05726890
- Testing
- bedtime intervention for early childhood insomnia, bedtime and nighttime intervention for early childhood insomnia
- Where
- Israel
- Volunteers
- 270 people
- Sponsor
- Ben-Gurion University of the Negev
Major Depressive Disorder, Bipolar Disorder
Imaging mGluR5 and Synaptic Density in Psychiatric Disorders
This research study is designed to look at the involvement of the glutamate system and synaptic density in depression and bipolar disorder. Each participant will undergo a screening appointment to determine study eligibility.
- Conditions
- Major Depressive Disorder, Bipolar Disorder, Healthy
- Trial name
- NCT03898297
- Testing
- [18F]FPEB, [11C]APP311
- Where
- United States
- Volunteers
- 79 people
- Sponsor
- Yale University
Developmental, Behavioral and Mental Health, Adhd
Using Telehealth to Deliver Mental Health Services in Primary Care Settings for Children in Underserved Areas
In partnership with a multi-site, Los Angeles-area community clinic consortium, North East Valley Health Corporation (NEVHC), the investigators will use telehealth to integrate pediatric developmental, behavioral and mental…
- Conditions
- Developmental, Behavioral and Mental Health, Adhd, Depression, Anxiety
- Trial name
- NCT02396576
- Testing
- Telehealth Intervention
- Where
- 6 sites in United States
- Volunteers
- 359 people
- Sponsor
- University of California, Los Angeles
Quadriplegia
Study of Combined Intercostal and Diaphragm Pacing for Artificial Respiration in Quadriplegic Patients
OBJECTIVES: I. Determine whether combined intercostal muscle and diaphragm pacing can maintain full-time ventilatory support in patients with ventilatory dependent quadriplegia who are not candidates for phrenic nerve pacing…
- Trial name
- NCT00004415
- Testing
- Medlink spinal cord electrode
- Volunteers
- 5 people
- Sponsor
- Case Western Reserve University
Alcohol Drinking
Engaging General Practice in the Prevention of Patients With Alcohol Problems
The aim of the study is to test whether or not a tailored multi-component intervention program to increase the activity of general practice teams in the prevention of hazardous and harmful alcohol consumption results in increase…
- Trial name
- NCT00298220
- Testing
- Feedback about patients at risk, Dissemination guideline and patient information letters, Tailored educational training
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- Radboud University Medical Center
Pediatric Cancer, Oncology
Feasibility and Acceptability of Internet-based Parent-child Interaction Therapy (I-PCIT) in Pediatric Cancer
This study is being done to learn whether a telehealth intervention called "Internet-Based Parent Child Interaction Therapy," or I-PCIT," can help parents improve the child's behavior if the child currently or previously went…
- Conditions
- Pediatric Cancer, Oncology, Disruptive Behavior
- Trial name
- I-PCIT (NCT06346782)
- Testing
- Internet-Based Parent-Child Interaction Therapy
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- Johns Hopkins All Children's Hospital
Autism Spectrum Disorder, Irritability
Behavior Therapy for Irritability in Autism
This is a clinical trial of a novel intervention, Behavioral Therapy for Irritability and Aggression (BTIA), for adolescents on the autism spectrum.
- Conditions
- Autism Spectrum Disorder, Irritability, Disruptive Behavior, Anger
- Trial name
- BTIA (NCT04654260)
- Testing
- Behavioral Therapy for Irritability in Autism, Psychoeducation and Supportive Therapy (PST)
- Where
- United States
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Yale University
PTSD
Cognitive-behavioral Therapy for Treatment of Post-traumatic Stress Disorder and Related Problems
The purpose of this study is to evaluate the efficacy of a form of cognitive behavioral therapy (CBT) in a population of individuals with PTSD and common related problems (depression, anxiety or sleep disorders, pain…
- Trial name
- CBT-PTSD-RP (NCT03019497)
- Testing
- Specific Modules, Cognitive behavioral therapy
- Where
- Canada
- Volunteers
- 92 people
- Sponsor
- Université de Montréal
Breast Diseases, Mastitis Granulomatous
A Randomized Controlled Study of Conservative Treatment of Granulomatous Lobular Mastitis Combined With Psychiatric Disorders
Granulomatous lobular mastitis (GLM) is a relatively rare chronic inflammatory disease of the breast in clinical practice. A small number of patients develop hyperprolactinemia during psychiatric drug treatment, and most of these…
- Conditions
- Breast Diseases, Mastitis Granulomatous, Psychiatric Disorder
- Trial name
- GLMwPD (NCT05395949)
- Testing
- conservative treatment
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Wuhan University
Mental Health Issue, Mental Health Disorder
Intervention to Address Disparate Mental Health Consequences of COVID-19 Pandemic on Latinx and African Newcomers
This study tests the effectiveness of a community-based peer advocacy, mutual learning, and social support intervention (Refugee and Immigrant Well-being Project) to reduce several negative consequences of the COVID-19 pandemic…
- Conditions
- Mental Health Issue, Mental Health Disorder, Stress, Emotional, Economic Problems
- Trial name
- RIWP+ (NCT05092542)
- Testing
- Refugee and Immigrant Well-being Project (RIWP)
- Where
- United States
- Volunteers
- 1,212 people, healthy volunteers welcome
- Sponsor
- University of New Mexico