Clinical trials: Behavioral Risks of Cancer
Anal Dysplasia, Human Papillomavirus
The HPV-SAVE Study Team: HPV Screening and Vaccine Evaluation in Men Who Have Sex With Men
Human papillomavirus (HPV) is the most common sexually transmitted infection worldwide. Infection by certain high-risk oncogenic types of HPV (HR-HPV) is the major cause of several cancers in men, notably squamous cell carcinoma…
- Conditions
- Anal Dysplasia, Human Papillomavirus, Anal Cancer
- Trial name
- HPV-SAVE (NCT02503111)
- Testing
- The Hyfrecator ® 2000 Electrosurgical System, Observation Alone
- Where
- 4 sites in Canada
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- University Health Network, Toronto
Epigenetics, DNA Methylation
Methylated Biomarkers of Smoking as a Selection Tool in Participants for Lung Cancer Screening
The MET-SELS study aims to revolutionize how we identify individuals for lung cancer screening by moving beyond the limitations of self-reported smoking history.
- Conditions
- Epigenetics, DNA Methylation, Lung Cancer Screening, Risk Stratification With Biomarker
- Trial name
- MET-SELS (NCT07631624)
- Testing
- DNA-methylation in saliva
- Where
- Belgium
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- University Hospital, Antwerp
Prostate Cancer
Improving Engagement From Underserved Communities With Prostate Cancer Genetics Services
Earlier work explored barriers and facilitators to accessing prostate cancer screening, particularly in underserved communities, and provided valuable insights to build upon.
- Trial name
- INCLUDE PC (NCT07407686)
- Testing
- Surveys, Semi-structured interviews and focus groups
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Royal Marsden NHS Foundation Trust
Risk Behavior
Pro-Change Population Health Solution
Patients with co-occurring health risk behaviors suffer greater morbidity, disability, and premature death. The Pro-Change Population Health Solution (PCPHS) is a suite of mobile tools designed to assist patients and primary care…
- Trial name
- PCPHS (NCT02755636)
- Testing
- PCPHC, Usual care
- Where
- 2 sites in United States
- Volunteers
- 780 people, healthy volunteers welcome
- Sponsor
- Pro-Change Behavior Systems
Breast Cancer
Mammogram Mail- and Phone-based Interventions
The project aims to evaluate four different versions and modalities of interventions encouraging mammogram screening among all eligible women due or overdue for screening.
- Trial name
- NCT05853848
- Testing
- Postcard, Letter, Auto-dialer
- Where
- United States
- Volunteers
- 14,386 people, healthy volunteers welcome
- Sponsor
- Geisinger Clinic
Dietary Habits
Dietary Factors and Risk of Gallbladder Carcinoma in China
The purpose of this study is to see how people's diets, other aspects of their lifestyles affect their chances of getting gallbladder carcinoma in China.
- Trial name
- DRGBC001 (NCT03546296)
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Yingbin Liu, MD, PhD, FACS
Risk Reduction, Breast Cancer
Phase IIB Trial of Bazedoxifene Plus Conjugated Estrogens
Women at risk for development of breast cancer and experiencing vasomotor menopausal symptoms (hot flashes) will be randomized to bazedoxifene (BZA) plus conjugated estrogens (CE) for 6 months versus a wait list control.
- Trial name
- NCT04821141
- Testing
- Bazedoxifene and Conjugated Estrogens
- Where
- 6 sites in United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Kansas Medical Center
Cervical Cancer Screening, Cervical Cancer
Evaluation of Three Strategies Based on Vaginal Self-sampling Kit Send to Home of Unscreened Women for Cervical Cancer
Despite the existence of an effective screening test (pap smear), cervical cancer is, every year in France, the cause of more than 3,000 new cases and 1,100 deaths.
- Trial name
- APACHE-4 (NCT03856684)
- Testing
- Self-sampling kit sent at home, Self-sampling kit sent at home + SMS reminder, Letter offering a self-sampling kit "on request"+ SMS reminder
- Where
- France
- Volunteers
- 10,400 people, healthy volunteers welcome
- Sponsor
- University Hospital, Tours
Healthy Subject
Eat, Move, Live Intervention in Reducing Chronic Disease Risk in Medically Vulnerable Communities
This randomized pilot research trial studies how well Eat, Move, Live (EML) works in reducing chronic disease risk in medically vulnerable communities.
- Trial name
- NCT02513407
- Testing
- Behavioral Dietary Intervention, Educational Intervention, Exercise Intervention
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- City of Hope Medical Center
Time Restricted Eating, Obesity
Time-restricted Eating Versus Daily Continuous Calorie Restriction on Body Weight and Colorectal Cancer Risk Markers
Approximately 42% of American adults are obese, and this condition is strongly related to the development of colorectal cancer. Innovative lifestyle strategies to treat obesity and reduce colorectal cancer risk are critically…
- Conditions
- Time Restricted Eating, Obesity, Weight Loss, Colorectal Cancer
- Trial name
- NCT05114798
- Testing
- Time restricted eating, Calorie Restriction
- Where
- United States
- Volunteers
- 194 people, healthy volunteers welcome
- Sponsor
- University of Illinois Chicago
Behavior, Risk
Human Laboratory Study of the Effects of Nicotine Product Claims on Appeal, Perceptions, and Use Behavior
This study evaluates knowledge, feelings and thoughts regarding nicotine products among young adults who are susceptible to but do not use tobacco/nicotine and adults who use tobacco/nicotine.
- Trial name
- NCT06192316
- Testing
- 3x3 between-subjects experimental exposure
- Where
- United States
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- Ohio State University Comprehensive Cancer Center
Smoking Cessation
Impact of a Gene Test for Susceptibility to Lung Cancer in Smokers
Professor RP Young (Associate Professor of Medicine and Molecular Medicine, School of Biological Sciences, University of Auckland) and his team have developed a reliable genetic test "Respiragene" based on 20 single nucleotide…
- Trial name
- NCT01176383
- Testing
- Respiragene test and risk score
- Where
- United Kingdom
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- Sussex NHS Research Consortium
Dermatology/Skin - Other, Health Behavior
Project Options - The ABC Method
The present study explores the ability of dermatologists to influence patients' behavior using a novel and brief (3 minute) behavioral intervention in the context of naturally occurring patient interactions and shows promise for…
- Conditions
- Dermatology/Skin - Other, Health Behavior, Sunburn
- Trial name
- NCT03489356
- Testing
- Addressing Behavior Change (ABC)
- Where
- United States
- Volunteers
- 186 people, healthy volunteers welcome
- Sponsor
- Penn State University
Obesity, Colorectal Cancer
Time-Restricted Eating and Mindfulness-Based Stress Reduction to Reduce the Risk of Early-Onset Colorectal Cancer
The goal of this clinical trial is to evaluate the feasibility of remote time-restricted eating (TRE) and mindfulness-based stress reduction (MBSR) interventions and the preliminary effect on EOCRC-related markers.
- Conditions
- Obesity, Colorectal Cancer, Microbial Colonization, Time Restricted Feeding
- Trial name
- MBSR&TRE (NCT06022887)
- Testing
- TRE, MBSR
- Where
- United States
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Lisa Tussing-Humphreys
Cancer, Gastrointestinal Cancer
Long-term Cancer Risk in the Randomised Oslo Diet and Antismoking Study
This study examines the effect of a five-year multifactorial lifestyle intervention in the Oslo diet and antismoking study on long-term cancer risk.
- Conditions
- Cancer, Gastrointestinal Cancer, Lung Cancer, Urinary Tract Cancer
- Trial name
- NCT03410641
- Testing
- Diet and antismoking advice
- Volunteers
- 1,216 people, healthy volunteers welcome
- Sponsor
- Oslo University Hospital
Lung Neoplasms, Stomach Neoplasms
Default Option Nudging Intervention to Improve the Adherence Rates of Cancer Screening
The goal of this clinical trial is to learn if a behavioral "nudge" strategy, specifically a default option, can improve screening participation in populations at high risk for lung and stomach cancer.
- Conditions
- Lung Neoplasms, Stomach Neoplasms, Early Detection of Cancer, Patient Compliance
- Trial name
- NCT07682220
- Testing
- Default Options
- Where
- China
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- Harbin Medical University
Health Risk Behaviors
A Prospective Study for the Early Diagnosis of Lung Cancer in Korean Females
This is a single-arm prospective pilot study in a single institution. The target accrual is 200 participants of Korean, female sex, never smoker status, and family history of lung cancer.
- Trial name
- NCT06181929
- Testing
- Low dose CT
- Where
- South Korea
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Sang-Won Um
Behavioral Risks of Cancer
The Effect of Mobile Text Message on Behavioral Risks of Cancer: A Randomized Controlled Trial
Summary Background: Cancer is a public health problem in Ethiopia. A third of cancer deaths are preventable. Its effects can be significantly reduced if effective interventions are put in place to control risk factors.
- Trial name
- NCT04269018
- Testing
- Cancer specific Mobile text message, General health messages
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Wollo University
Breast Neoplasms Diagnosis
Breast Cancer Risk Assessment in Night Shift Workers - Implementation of a Personalized Consultation
This study evaluates adherence to a personalized prevention plan in female night shift workers at increased risk of breast cancer.
- Trial name
- NIGHT-SCAN (NCT07630935)
- Testing
- Personalized Prevention Plan
- Where
- France
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Behavior, Risk
Breast Cancer Study Tracking Risk Awareness of Alcohol Consumption and Improving Knowledge in Young Adult Women
This randomized trial aims to test the effects of co-created breast cancer counter marketing intervention messages for reducing alcohol consumption and impacting awareness and beliefs about the breast cancer risks from alcohol…
- Trial name
- B-Track (NCT07320664)
- Testing
- Alcohol and Breast Cancer Risk Messages, Skin Cancer Risk Messages
- Where
- United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Ohio State University Comprehensive Cancer Center