Clinical trials: Behavioral Risks of Cancer
Cancer, Physical Inactivity
Study of Clinic-delivered Physical Activity Referrals to Cancer Survivors
Background: Cancer survivors have a greater risk of cardiovascular disease (CVD) and have low physical activity levels. Physical inactivity is one modifiable risk factor for CVD, and increased physical activity has shown a…
- Trial name
- NCT05216380
- Testing
- ActivityLink
- Where
- United States
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- University of Massachusetts, Worcester
Smoking Cessation, Micronuclei
ESTxENDS Trial: MN Substudy - Micronuclei in Buccal Epithelium, a Surrogate Measure of Future Cancer Risk, Induced by Electronic Nicotine Delivery Systems (ENDS/Vaporizer/E-cig)
--> This is a substudy of the main ESTxENDS trial (NCT03589989). Micronuclei in buccal epithelial outcomes should be considered secondary outcomes of the main smoking cessation outcome formulated in NCT03589989.
- Trial name
- ESTxENDS (NCT04244773)
- Testing
- ENDS (vaporizer/e-cig) and smoking cessation counseling, Smoking cessation counseling
- Where
- 5 sites in Switzerland
- Volunteers
- 1,246 people, healthy volunteers welcome
- Sponsor
- University of Bern
Breast Cancer, Overweight and Obesity
Acceptance and Usability of an App Promoting Healthy Behaviours Amongst Young Women at Increased Risk of Breast Cancer
It is estimated that around 20% of breast cancers (BC) in the UK are preventable through adherence to appropriate health behaviours, i.e., healthy diet, physical activity, limited alcohol, not smoking, and that women at increased…
- Conditions
- Breast Cancer, Overweight and Obesity, Diet, Healthy, Weight Gain
- Trial name
- NCT05460650
- Testing
- App Promoting Healthy Behaviours
- Where
- United Kingdom
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- University of Manchester
Colorectal Cancer
The Biomarkers Of RIsk of Colorectal Cancer (BORICC) Follow-Up (BFU) Study
Worldwide, colorectal cancer is the 3rd most common cancer; risk increases with age and is modified by lifestyle factors notably diet, physical activity and obesity.
- Trial name
- BFU (NCT04005742)
- Where
- United Kingdom
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Newcastle University
Suicide, Attempted, Suicidal Ideation
Biomarkers as Predictors of Suicidal Risk in Adolescents
Suicide is one of the most devastating events in society at all levels. The primary goal of this study is to predict suicide in adolescents at risk.
- Conditions
- Suicide, Attempted, Suicidal Ideation, Suicidal Intention, Suicide
- Trial name
- NCT03014518
- Testing
- Clinical assessments and blood samples; follow-up for 12 mos, Clinical assessments and blood samples; no 12mo follow-up
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- The Cleveland Clinic
Health Knowledge, Attitudes, Practice, Alcohol Consumption
Increasing Knowledge of Alcohol as a Risk Factor for Breast Cancer Among Women Attending Breast Screening Services
Alcohol is a major modifiable risk factor for breast cancer in women, yet this is not widely understood by health practitioners or policy makers, let alone the general population.
- Trial name
- Health4Her (NCT04715516)
- Testing
- alcohol brief intervention, lifestyle health promotion
- Where
- Australia
- Volunteers
- 558 people, healthy volunteers welcome
- Sponsor
- Turning Point
Cancer
ORCA: Opportunities to Raise Cancer Awareness After Referral: Survey of Patient Views
The purpose of this study is to investigate what patients think about increasing provision of advice about how to detect cancer early and how to reduce their future cancer risk after they are discharged from a two-week wait…
- Trial name
- ORCA (NCT05479851)
- Where
- United Kingdom
- Volunteers
- 406 people, healthy volunteers welcome
- Sponsor
- King's College London
Cervical Cancer
Increasing Participation in Cervical Cancer Screening and Risk for Beliefs/Attitudes Among Women at Risk
In order to evaluate the effectiveness of nursing interventions aimed at the early detection of cervical cancer, health belief and participation in the screening of women aged 40-55 at risk for the purpose of cervical cancer…
- Trial name
- NCT03076879
- Testing
- Promoting participation in cervical cancer screening
- Where
- Turkey (Türkiye)
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- Selcuk University
Sarcopenia, Pediatric Cancer
Determination of Sarcopenia Risk and Related Factors in Pediatric Oncological Patients
In children, both malnutrition and sarcopenia are associated with prolongation of hospital stay, increased morbidity, mortality, and health-related complications.
- Trial name
- NCT05294380
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Trakya University
Feasibility Pilot Study, Compliance
A Low-Insulinemic Dietary Intervention to Reduce Breast Cancer Risk in High-Risk Women
This clinical trial tests whether a new dietary pattern that consists of foods that lower the blood insulin response can reduce breast cancer risk in high-risk women.
- Trial name
- LIN-BRiCK (NCT06635005)
- Testing
- Biospecimen Collection, Dietary Intervention, Medical Device Usage and Evaluation
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Ohio State University Comprehensive Cancer Center
Diet Modification, Physical Activity
Denver Garden Environment and Microbiome Study Disease
An interdisciplinary team with extensive garden study experience conducted a pilot randomized controlled clinical trial to see whether gardening reduced risk factors for diseases like cancer and heart disease.
- Conditions
- Diet Modification, Physical Activity, Weight Gain, Chronic Disease
- Trial name
- DGEM (NCT03089151)
- Testing
- Community Garden Intervention
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Boulder
Intervention
Protocol: Feasibility of an Online Intervention to Increase Awareness of Gynaecological Cancer in UK Students
In the UK more than 2500 young people are diagnosed with cancer each year, including gynaecological cancers) and almost a third will be diagnosed within accident and emergency departments.
- Trial name
- GoCheck (NCT07147283)
- Testing
- Educational film and volitional help sheet
- Where
- United Kingdom
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Leeds Beckett University
Polycystic Ovary Syndrome, Hypothalamic Amenorrhea
Body Fat as Determinant of Female Gonadal Dysfunction
Reproduction requires from women enough energy depots to warrant an adequate nutritional supply to the fetus. Hence, adipose tissue is able to communicate with female hypothalamic-pituitary-ovary axis.
- Trial name
- NCT03841981
- Testing
- Anthropometric and physical examination, Indirect calorimetry, accelerometer and seven-day dietary recall, Biochemical, hormonal and metabolic phenotyping
- Where
- Spain
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Fundacion para la Investigacion Biomedica del Hospital Universitario Ramon y Cajal
Lung Cancer, COPD (Chronic Obstructive Pulmonary Disease) With Acute Lower Respiratory Infection
Lung Cancer Prevention Screening Programme in Italy
This prospective randomized multicentered clinical study aims at implementing early diagnosis of lung cancer in high-risk heavy smokers in the Italian population.
- Conditions
- Lung Cancer, COPD (Chronic Obstructive Pulmonary Disease) With Acute Lower Respiratory Infection, Cardiovascular Diseases
- Trial name
- RISP (NCT05766046)
- Testing
- early lung cancer detection, blood test
- Where
- Italy
- Volunteers
- 7,324 people, healthy volunteers welcome
- Sponsor
- Ugo Pastorino
Breast Neoplasm, Primary Prevention
Project Breast47: Effect of an Educational Intervention
Breast cancer is the most frequently diagnosed malignant tumor in women. In 2018, in Spain, the estimated incidence was 101/100,000 women.
- Conditions
- Breast Neoplasm, Primary Prevention, Risk Factors, Telemedicine
- Trial name
- Breast47 (NCT05267171)
- Testing
- Web access
- Where
- Spain
- Volunteers
- 451 people, healthy volunteers welcome
- Sponsor
- University of Oviedo
Cancer Screening, Early Detection of Cancer
Risk Reduction Program for Women Having High Risk of Breast Cancer
An intervention program involving education, guidance, counseling, case management and surveillance based on the Health Belief Model will be implemented on women with high risk of breast cancer.
- Conditions
- Cancer Screening, Early Detection of Cancer, Breast Cancer, Preventive Health Care
- Trial name
- BrCaRRP (NCT04304404)
- Testing
- Breast Cancer Risk Reduction Program (BrCaRRP)
- Where
- Turkey (Türkiye)
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- Akdeniz University
Cancer of the Colon
Behavioral Economic Incentives and Cancer Health Risk Assessment
This is an RCT among UPHS employees between ages 50-64 comparing no incentive and a loss-framed incentive for completing cancer health risk assessment.
- Trial name
- NCT03068052
- Testing
- No incentive, Incentive
- Where
- United States
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Diet Habits, Cancer Prevention
Dietary Fiber and Time Restricted Eating
This study is seeking to examine combinations of two different dietary interventions on cancer risk.
- Trial name
- FIBER+TRE (NCT07219706)
- Testing
- Time Restricted Eating, Group education, Counseling
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Oklahoma
Diabetes, Hypercholesterolaemia
The Effect of Providing Genetic Risk Information on Lifestyle Behaviors in African Americans
Cardiovascular disease (CVD) is a major and persistent health disparity for African Americans. Linking GAINS is a randomized pilot and feasibility study designed to evaluate whether receiving genetic risk information early in a…
- Conditions
- Diabetes, Hypercholesterolaemia, Hypertension, Obesity Type 2 Diabetes Mellitus
- Trial name
- LINKING GAINS (NCT07833384)
- Testing
- Color Genomics Genetic Testing Panels
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Pennington Biomedical Research Center
Women's Health: Neoplasm of Breast
Breast Cancer: Feasibility of an Educational Intervention
Aim: To evaluate the viability of an educational intervention for the prevention of breast cancer risk and the modification of their risk behaviors through the use of a web application in women living in the Principality of…
- Trial name
- PRECAM-2 (NCT04396665)
- Testing
- Precam
- Where
- Spain
- Volunteers
- 224 people, healthy volunteers welcome
- Sponsor
- University of Oviedo