Clinical trials: Behavioral Symptom, open to volunteers
Chronic Insomnia, Overweight/Obesity
Cognitive Behavioral Therapy for Insomnia as an Adjunct to Time-restricted Eating on Weight Loss in Adults With Overweight or Obesity and Chronic Insomnia
Obesity (being overweight due to excess body fat) is a common health condition that increases the risk of developing problems such as diabetes, high blood pressure, and heart disease.
- Trial name
- NCT07770516
- Testing
- Flexible Time-restricted eating group (FTRE), Flexible Time-restricted eating plus cognitive behavioural therapy for insomnia group (CBTI+FTRE)
- Where
- Hong Kong
- Volunteers
- 50 people
- Sponsor
- Chinese University of Hong Kong
Outpatients or Inpatients With Depression
A Multicenter Real-World Study Evaluating the Efficacy and Safety of Shugan Jieyu Capsules in the Treatment of Depression
To observe the efficacy and safety of Shugan Jieyu Capsules in treating patients with varying degrees of depression in real-world clinical settings, and to provide data references for optimizing integrated traditional Chinese and…
- Trial name
- NCT07785284
- Testing
- Shugan Jieyu Capsules
- Where
- China
- Volunteers
- 400 people
- Sponsor
- Peking University
Acute Disease, Sepsis
Acutelines: a Large Data-/Biobank of Acute and Emergency Medicine
Research in acute care faces many challenges, including enrollment challenges, legal limitations in data sharing, limited funding, and lack of singular ownership of the domain of acute care.
- Conditions
- Acute Disease, Sepsis, Pneumonia, Frailty
- Trial name
- Acutelines (NCT04615065)
- Where
- Netherlands
- Volunteers
- 35,000 people
- Sponsor
- University Medical Center Groningen
Gynecologic Cancer, Prostate Cancer
CARE Tool Study Aim 3
This study is a multi-site randomized trial to study the implementation of the CARE Tool and evaluate the CARE Tool. The CARE Tool is a web-based tool that gives people information about cancer care costs, health insurance, and…
- Conditions
- Gynecologic Cancer, Prostate Cancer, Lung Cancer, Colorectal Cancer
- Trial name
- NCT07296887
- Testing
- Financial education information, CARE Tool, CARE Tool Training
- Where
- 3 sites in United States
- Volunteers
- 430 people
- Sponsor
- Washington University School of Medicine
Non-communicable Diseases (NCD), Addiction to Opioids
Systematic Examination of Health Inequalities: Documentation, Patterns, and Determinants
The existence of social inequalities is a major global issue and a salient challenge for the European Union. During COVID-19 pandemic, health disparities became more evident.
- Conditions
- Non-communicable Diseases (NCD), Addiction to Opioids, Incarceration, Opioid-use Disorders
- Trial name
- CHANCE (NCT07558187)
- Where
- 5 sites in Greece
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- University of Thessaly
Heart Failure, Frailty
INTEgRated Health CARE for Patients With Frailty and Heart Failure
Frailty, an aging-related syndrome of physiological decline characterized by marked vulnerability to adverse health outcomes, has attracted increasing attention in cardiology due to the growing elderly population with heart…
- Conditions
- Heart Failure, Frailty, Frail Elderly Syndrome, Symptom, Behavioral
- Trial name
- INTERCARE-HF (NCT06444321)
- Testing
- INTERCARE-HF
- Where
- Norway
- Volunteers
- 60 people
- Sponsor
- Vestre Viken Hospital Trust
Sleep Quality, Mood
A Clinical Trial to Evaluate the Effects of the Edge+Ease PM+AM System on Mood, Mental Clarity, Sleep Quality, and Digestive Wellbeing
This is a decentralized, single-arm, open-label clinical trial evaluating the effects of the Edge+Ease PM+AM dietary supplement system on sleep quality, mood, mental clarity, focus, and digestive comfort in 35 generally healthy…
- Conditions
- Sleep Quality, Mood, Mental Clarity, Brain Fog
- Trial name
- NCT07721506
- Testing
- Edge+ease PM
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Edge+Ease
Limitation, Mobility, Older Adults
SuPA Mobility: Supporting Physical Activity for Mobility in Mobility-Limited Older Adults
The goal of this randomized controlled trial is to investigate the effectiveness of a health-coaching intervention to improve physical activity in older adults with limited mobility when compared to a control, health education…
- Trial name
- NCT05978336
- Testing
- Health Coaching Program, Health Education Program
- Where
- Canada
- Volunteers
- 290 people
- Sponsor
- University of British Columbia
Binge Eating, Binge Drinking
Brief Binge Eating and Drinking Online Intervention
This pilot project targets both binge drinking and binge eating behavior in college students through a mobile-based online program that provides students with evidence-based intervention material designed to reduce the incidence…
- Trial name
- NCT06326099
- Testing
- Brief Online Binge Eating and Drinking Intervention
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Traumatic Brain Injury, Disruptive Behavior
Parent-Child Interaction Therapy (PCIT) for Children With Traumatic Brain Injury (TBI): A Stepped-Care Model
The purpose of this study is to understand how a stepped-care model of Parent-Child Interaction Therapy (Step-Up PCIT) addresses child behavioral problems among children between the ages of 2 and 7 with a traumatic brain injury…
- Trial name
- NCT06193382
- Testing
- PCIT
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Miami
Chronic Pain
Brief Mindfulness-Oriented Recovery Enhancement vs Brief Cognitive-Behavioral Therapy for Chronic Pain
This randomized controlled trial aims to test both English and Spanish versions of two, benign behavioral interventions for adults with chronic pain -- 1) Brief Mindfulness-Oriented Recovery Enhancement (B-MORE), and 2) Brief…
- Trial name
- B-MORE v B-CBT (NCT07207174)
- Testing
- Brief Mindfulness Oriented Recovery Enhancement, Brief Cognitive-Behavioral Therapy
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Florida State University
Opioid Use, Stimulant Use
Leveraging mHealth to Promote Opioid Use Recovery and Mental Health Among Residents of a Medium-Sized Midwestern City
The sequential trial compares recovery and mHealth engagement outcomes among Black participants who participated in the mHealth intervention uMAT-R or uMAT-R + enhanced community engagement.
- Conditions
- Opioid Use, Stimulant Use, Depression and Anxiety Symptoms
- Trial name
- NCT07673380
- Testing
- uMAT-R + enhanced community engagement, Original uMAT-R supplementary mHealth recovery intervention
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- Washington University School of Medicine
Perianal Fistula, Fistula-in-Ano
Open Fistulectomy vs. Laser Closure for Low Perianal Fistula
Perianal fistula is an abnormal tunnel connecting the anal canal to the perianal skin, frequently causing chronic pain, discharge, and impaired quality of life.
- Conditions
- Perianal Fistula, Fistula-in-Ano, Low Perianal Fistula
- Trial name
- NCT07797842
- Testing
- Fistula-tract Laser Closure (FiLaC), Open Fistulectomy
- Volunteers
- 40 people
- Sponsor
- Assiut University
Mental Fatigue
Music Intervention on Golfers Under Mental Fatigue
This study aims to evaluate the effects of music intervention on golf-specific skill performance under mental fatigue. It is a randomised, controlled, double-blind design.
- Trial name
- NCT06952283
- Testing
- Inducing mental fatigue, Music intervention
- Where
- Malaysia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Pan Xiaoyang
Burnout Risk
Burnout Intervention During War for Hospital Staff in Ukraine
The project endeavours to investigate the feasibility and acceptability of a psychoeducational training intervention for professional burnout and related psychological variables among both medical and non-medical workers in…
- Trial name
- NCT07620756
- Testing
- Burnout prevention
- Where
- Ukraine
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Charite University, Berlin, Germany
Leukemia, Acute Leukemia
Strength Training Exercise in Pediatric Acute Lymphoblastic Leukemia and Lymphoblastic Lymphoma (STEP-ALL)
Acute lymphoblastic leukemia (ALL) is the most common cancer in children and, along with lymphoblastic lymphoma, represents the most common group of childhood lymphoid malignancies.
- Conditions
- Leukemia, Acute Leukemia, Acute Lymphoid Leukemia, Lymphoblastic Lymphoma
- Trial name
- STEP-ALL (NCT07634653)
- Testing
- Exercises
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- UNC Lineberger Comprehensive Cancer Center
Depression Disorders
The Use of SmartPhone App (Kandoo) to Enhance Efficacy of Brief Behavioral Activation in Reducing Mood Disorder Symptoms
The current project is a pilot study that seeks to compare the efficacy of Brief Behavioral Activation's treatment-as-usual that uses paper and pencil tools to Kandoo, a digital, gamified version of activity scheduling and…
- Trial name
- Kandoo (NCT06825637)
- Testing
- Kandoo
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Child Mind Institute
Amyotrophic Lateral Sclerosis, Neuromuscular Disease
Connect-One: Early Feasibility Study of Connexus® Brain-Computer Interface (BCI)
The Connect-One Study is an early feasibility study to obtain preliminary device safety information for the Connexus Brain-Computer Interface (BCI).
- Conditions
- Amyotrophic Lateral Sclerosis, Neuromuscular Disease, Stroke, Tetraplegia/Tetraparesis
- Trial name
- CONNECT-ONE (NCT07357428)
- Testing
- Connexus Brain-Computer Interface
- Where
- 3 sites in United States
- Volunteers
- 2 people
- Sponsor
- Paradromics
Psychological Stress
Feasibility Pilot of Remote Mindfulness Training Across Multiple Sites (REFORM Pilot)
This is an operational feasibility pilot preceding the main REFORM multi-site randomized controlled trial. Approximately 60 adults across three sites will be randomized equally to one of four remotely delivered audio-guided…
- Trial name
- REFORM Pilot (NCT07888725)
- Testing
- Formal-Heavy Audio-Guided Mindfulness Training, Balanced Audio-Guided Mindfulness Training, Informal-Heavy Audio-Guided Mindfulness Training
- Where
- Singapore
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Institute for Human Development and Potential (IHDP), Singapore
Diabetes-Related Complications
Study on the Molecular Mechanism of Berberine to Improve Type 2 Diabetes Mellitus Complicated With Depression
The incidence of type 2 diabetes with comorbid depression (T2DD) is notably high, characterized by prolonged disease duration and susceptibility to recurrence.
- Trial name
- SBDD (NCT06979440)
- Testing
- No intervention
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Affiliated Hospital of Nantong University
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