Clinical trials: Behaviors, Health
Substance-Related Disorders, Recidivism
Alliances to Disseminate Addiction Prevention and Treatment (ADAPT)
Youth involved in the juvenile justice system (YJJ) bear a disproportionate burden of the addiction crisis. YJJ substance use (SU) is extremely prevalent, with a third of YJJ meeting criteria for a substance use disorder (SUD).
- Conditions
- Substance-Related Disorders, Recidivism, Opioid-Related Disorders, Substance Use
- Trial name
- ADAPT (NCT04499079)
- Testing
- Learning Health System
- Where
- United States
- Volunteers
- 7,316 people
- Sponsor
- Indiana University
Methamphetamine Use, Heart Failure
Rural Community Peer Partnerships for Improving Methamphetamine-Associated Heart Failure Screening and Engagement
The goal of PEER-Heart is to implement and assess feasibility and preliminary effectiveness of a community peer-facilitated screening for methamphetamine-associated heart failure (MAHF) and linkage to evidence-based cardiology…
- Trial name
- PEER-Heart (NCT06461962)
- Testing
- Treatment as Usual, Telehealth-Cardiology
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Oregon Health and Science University
Vision and Hearing Loss, Vision Impairment
SENSE-Brain Health Pro for Older Adults With Sensory Loss
The goal of this study is to learn about the outcomes, usability, and accessibility of the online Brain Health Pro program for older adults with hearing difficulties, vision difficulties, or both.
- Conditions
- Vision and Hearing Loss, Vision Impairment, Hearing Impairment, Vision Difficulty
- Trial name
- SENSE-BHPro (NCT07856888)
- Testing
- Brain Health Pro
- Where
- Canada
- Volunteers
- 300 people
- Sponsor
- Université de Montréal
Young Older Adults
The PreventIT Trial in Young Older Adults, Comparing Two Lifestyle-integrated Exercise Interventions
The feasibility randomised controlled trial is part of the EU funded project "PreventIT" (2016-2018) responding to the Horizon 2020, Personalised health and care (PHC), call PHC-21: Advancing active and healthy ageing with ICT…
- Trial name
- PreventIT (NCT03065088)
- Testing
- aLIFE, eLIFE, control
- Where
- 3 sites in Germany, Netherlands and 1 more
- Volunteers
- 180 people
- Sponsor
- Norwegian University of Science and Technology
Osteoarthritis
STOP OA: A PILOT STUDY (GLA:D Canada) - Education and Targeted, Personalized Exercise for Hip and Knee Osteoarthritis
Osteoarthritis (OA) most often affects the hip and knee joints. The first signs and symptoms of pain, stiffness or swelling are not uncommon in those in their thirties and forties and 10 per cent report symptomatic knee OA by age…
- Trial name
- NCT02693873
- Testing
- GLA:D Canada (education and neuromuscular exercise program)
- Where
- Canada
- Volunteers
- 61 people
- Sponsor
- Aileen Davis
Postpartum Care, Primary Care
Maternal Health Assessment in Pediatric Care
The major goal of this study is to develop and pilot M-HARP (Maternal Health Assessment and Referral Integrated into Pediatric Care).
- Conditions
- Postpartum Care, Primary Care, Mental Health, Family Planning
- Trial name
- M-HARP (NCT07294573)
- Testing
- referral
- Where
- Dominican Republic
- Volunteers
- 150 people
- Sponsor
- John James Parker
Chronic Disease, Exercise
Implementing and Evaluating the Integration of Physical Activity Into a Major Health System and Connecting Patients to Physical Activity Programs.
Multiple case study trial examining the adoption, implementation, and reach of eligible patients visiting participating Prisma Health primary care clinics and receiving a referral to a 12-week evidence-informed physical activity…
- Conditions
- Chronic Disease, Exercise, Physical Activity
- Trial name
- NCT06073041
- Testing
- Invitation to adopt, Onboarding strategies
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of South Carolina
COPD
Implementation of an Evidence Based Smoking Cessation Strategy (SMOCC) for Patients With COPD in Primary Care
A controlled study demonstrated that a smoking cessation protocol in routine primary care, specifically targeted at patients with COPD (SMOCC), doubled the quit rates.
- Trial name
- NCT00294905
- Testing
- Implementation of a combined smoking cessation strategy
- Where
- Netherlands
- Volunteers
- 2,700 people
- Sponsor
- Radboud University Medical Center
Neoplasms, Communication
My Team of Care: a Pilot Randomized Controlled Trial of an Online Communication Tool for Collaborative Care
This project will pilot and test a new online communication tool, Loop, developed within a research framework with participatory and user-centred design. This pilot trial focuses on advanced cancer as an example of complex care.
- Trial name
- Loop (NCT02372994)
- Testing
- Loop
- Where
- 2 sites in Canada
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Mount Sinai Hospital, Canada
Dysmenorrhea, Premenstrual Syndrome-PMS
Improving Menstrual Health Through BCC Among Bangladeshi University Students
This study evaluated the effectiveness of a Behavior Change Communication (BCC) intervention in improving menstrual health among female university students in Bangladesh.
- Conditions
- Dysmenorrhea, Premenstrual Syndrome-PMS, Menstrual Irregularity
- Trial name
- NCT07047222
- Testing
- Behavioral change communication (BCC) module
- Where
- Bangladesh
- Volunteers
- 498 people, healthy volunteers welcome
- Sponsor
- Shahjalal University of Science and Technology
Generalized Anxiety, Social Phobia
Integrated Mental Health Care and Vocational Rehabilitation to Individuals on Sick Leave Due to Anxiety and Depression
The purpose of this study is to investigate the efficacy of 1) a stepped mental health care intervention and 2) an integrated mental health care and vocational rehabilitation intervention for people on sick leave because of…
- Conditions
- Generalized Anxiety, Social Phobia, Panic Disorder, Depression
- Trial name
- IBBIS (NCT02872051)
- Testing
- IBBIS mental health care and standard vocational rehabilitation, Integrated mental health care and vocational rehabilitation
- Where
- Denmark
- Volunteers
- 631 people
- Sponsor
- Amager Hospital
Breast Feeding
Prenatal Breastfeeding Education
In this pilot randomized control trial, the investigators will evaluate the feasibility and acceptability of using a video and website in a prenatal visit to provide breastfeeding education, focusing on how to hand express (HE)…
- Trial name
- NCT04549129
- Testing
- Breastfeeding education video, Breastfeeding website, Usual breastfeed education
- Where
- United States
- Sponsor
- Boston Medical Center
Maternal and Child Health Outcomes
Vitamins, Breastmilk HIV Shedding, and Child Health
The purpose of this study is to analyze stored samples and data collected during the conduct of the study "A Trial of Vitamins in HIV Progression and Transmission" (HD32257).
- Trial name
- NCT00197756
- Testing
- Vitamin A alone, Multivitamins excluding vitamin A, multivitamins including vitamin A
- Where
- United States
- Volunteers
- 771 people
- Sponsor
- Harvard School of Public Health (HSPH)
Cardiovascular Diseases, Cancer
Promoting Healthy Lifestyles Among Firefighters
Promoting Healthy Lifestyles: Alternative Models' Effects (PHLAME) is a research study to evaluate and compare two ways to promote healthy behaviors, (regular physical activity, less than 30% calories from fat, 5 or more servings…
- Conditions
- Cardiovascular Diseases, Cancer, Physical Activity, Nutrition
- Trial name
- PHLAME (NCT00006181)
- Testing
- Team-based intervention, One-on-one intervention
- Where
- United States
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Hypertension, Breakfast Skipper
Early Time-Restricted Eating for Cardiovascular Health
This study will examine whether eating earlier in the day within a consistent 8-hour eating window can improve heart and blood vessel health in older adults with high blood pressure who often skip breakfast.
- Trial name
- ALIGN (NCT07634926)
- Testing
- Early Time-Restricted Eating (eTRE)
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- University of Alabama at Birmingham
Prenatal Anxiety, Prenatal Depression
Effectiveness of an Online Biopsychosocial Intervention to Improve Well-being and Mental Health During Pregnancy
This study aims to develop and implement a preventive intervention through a mobile application to help pregnant women feel better emotionally and cope with the changes of pregnancy in a more positive way.
- Conditions
- Prenatal Anxiety, Prenatal Depression, Wellbeing, Obstetrical Complications
- Trial name
- BienGestar (NCT06871397)
- Testing
- Biopsychosocial Cognitive Behavioral Intervention
- Where
- Spain
- Volunteers
- 228 people, healthy volunteers welcome
- Sponsor
- University Rovira i Virgili
Prolapse
RCT: Impact of Preop Video on Patient Preparedness for Surgery
This is a single-blind, randomized (1:1 allocation), stratified, single-parallel clinical trial at one institution evaluating the use of a preoperative patient education video as an adjunct to preoperative counseling on…
- Trial name
- NCT02076360
- Testing
- Preoperative Video
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of South Florida
Physical Disability
Wheelchair User Physical Activity Training Intervention to Enhance Cardiometabolic Health
The goal of the study is to improve cardiometabolic health outcomes for wheelchair users and identify strategies for achieving sufficient physical activity intensity during bouts of structured physical activity.
- Trial name
- WATCH (NCT06013046)
- Testing
- Intensity-controlled physical activity training (IPAT), Education and Access (EA)
- Where
- United States
- Volunteers
- 108 people
- Sponsor
- Washington University School of Medicine
Basal Cell Carcinoma
Basal Cell Carcinoma Chemoprevention Trial
This is an intent-to-treat, parallel design, multicenter randomized trial and the primary intervention is a double-blind comparison of imiquimod (IMQ) vs.
- Trial name
- B3C (NCT05212246)
- Testing
- 5% Imiquimod cream
- Where
- 8 sites in United States
- Volunteers
- 1,630 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Health Behaviors, Obesity
Goal Setting for Health Behavior and Psychosocial Issues in Primary Care
The purpose of this delayed cluster randomized intervention trial is to evaluate primary care strategies to increase goal setting, shared decision-making and evidence-based support and counseling for health behaviors and…
- Conditions
- Health Behaviors, Obesity, Substance Abuse, Anxiety
- Trial name
- MOHR (NCT01825746)
- Testing
- Implementation of the MOHR assessment in primary care workflow
- Where
- 8 sites in United States
- Volunteers
- 3,591 people
- Sponsor
- Virginia Commonwealth University
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