Clinical trials: Behaviour
Autism, Asperger's Syndrome
Cognitive-Behavioral Treatment for Anxiety Disorders in Children With Autism Spectrum Disorders
Autism spectrum disorders affect as many as 1 out of 150 children and are related to significant impairment in social, adaptive, and school functioning.
- Conditions
- Autism, Asperger's Syndrome, Generalized Anxiety Disorder, Social Phobia
- Trial name
- NCT01178385
- Testing
- Cognitive-behavioral therapy, Treatment as Usual
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of South Florida
Smoking
Insular Inhibitory Neuromodulation to Reduce Cigarette Craving and Alter Brain Function in Smokers
The goal of this study is to determine if a specific experimental brain stimulation technique can be used as a non-invasive way to reduce cigarette cravings in current smokers.
- Trial name
- NCT02590640
- Testing
- Repetitive transcranial magnetic stimulation, MagStim Rapid2
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Temporomandibular Joint Disorders, Orofacial Pain
Occlusal Adjustment as Treatment for Chronic Orofacial Pain
The purpose of this study is to determine whether occlusal adjustment by selective grinding and/or occlusal addition is an effective treatment of chronic temporomandibular joint disorders.
- Trial name
- NCT00899717
- Testing
- Occlusal adjustment
- Where
- 2 sites in Spain
- Volunteers
- 21 people
- Sponsor
- University of Santiago de Compostela
Opioid Use, Alcohol Drinking
TACUNA (Traditions and Connections for Urban Native Americans)
This study responds to Request For Application-DA-19-035, HEAL (Helping End Addiction Long Term) initiative: Preventing OUD in Older Adolescents and Young Adults (ages 16-30) by developing and implementing a culturally centered…
- Conditions
- Opioid Use, Alcohol Drinking, Marijuana Use
- Trial name
- TACUNA (NCT04617938)
- Testing
- TACUNA plus Wellness Circle, Opioid Education Workshop
- Where
- 3 sites in United States
- Volunteers
- 541 people, healthy volunteers welcome
- Sponsor
- RAND
Attention Deficit Hyperactivity Disorder (ADHD)
Safety and Efficacy Study of SHP465 in Children and Adolescents Aged 6-17 Years With Attention-Deficit Hyperactivity Disorder (ADHD)
The study is designed to evaluate the efficacy and safety of SHP465 in the treatment of ADHD in children and adolescents (aged 6-17 years).
- Trial name
- NCT02466425
- Testing
- SHP465
- Where
- 36 sites in United States
- Volunteers
- 264 people
- Sponsor
- Shire
Peripheral Arterial Disease, Intermittent Claudication
Pain Management and Patient Education for Physical Activity in Intermittent Claudication (PrEPAID)
Peripheral Arterial disease is a common condition which causes narrowing of the arteries. The most common symptom that patients with PAD experience is Intermittent Claudication (IC), pain in the lower limb(s) on exertion, which…
- Trial name
- PrEPAID (NCT03204825)
- Testing
- Active TENS, Patient-Centred Education
- Where
- United Kingdom
- Volunteers
- 95 people
- Sponsor
- Glasgow Caledonian University
Cocaine Dependence, Alcohol Dependence
HBPL Study of the Impact of the NK1 Antagonist Aprepitant
The proposed research will focus on investigating the determinants and consequences of CAD via measurement of physiological, behavioral and subjective effects of physiologic and psychologic stress cues in CAD volunteers in the…
- Trial name
- NCT01176591
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- University of Pennsylvania
Post-Traumatic Stress Disorder
Treating People With Post-Traumatic Stress Disorder With Cognitive Behavioral Therapy for Insomnia
This study will test the effectiveness of cognitive behavioral therapy for insomnia in treating sleep disturbances in people with post-traumatic stress disorder.
- Trial name
- NCT00881647
- Testing
- Cognitive Behavioral Treatment for Insomnia (CBT-I)
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- University of California, San Francisco
Posttraumatic Stress Disorder, Depression
Examining Changes in Microbiota Over the Course of PTSD Treatment
The overall goals of this project are to evaluate the use of 5-day intensively-delivered Cognitive Processing Therapy to treat PTSD and to determine the associations between the microbiome, salivary cytokines, and the presence of…
- Trial name
- NCT04109196
- Testing
- Cognitive Processing Therapy
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Rush University Medical Center
Childhood Obesity
Physical Activity and Screen-Time Regulations in Childcare Centers - Aim 1
The goal of this project is to examine the physical activity and screen-time environment of licensed childcare centers before and after the enactment of new state regulations.
- Trial name
- Pause and Play (NCT02751788)
- Where
- United States
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Pennington Biomedical Research Center
Diabetes Mellitus, Type 2
Impact of Pharmacy Clinic on Diabetes Management
The Beaumont Hospital Royal Oak Outpatient Clinic (and other listed Beaumont recruiting locations) care for over 900 patients with diabetes.
- Trial name
- PharmaMD (NCT03377127)
- Testing
- Pharmacy Managed Diabetes Clinic (PMDC), Standard of Care (SOC)
- Where
- 4 sites in United States
- Volunteers
- 86 people
- Sponsor
- Corewell Health East
Medication Adherence
Imagine to Remember: Improving Medication Adherence in Pre- and Type 2 Diabetes
Determine if an intervention consisting of future-thinking improves different facets of memory/executive function and/or decision-making.
- Trial name
- NCT04157673
- Testing
- Episodic Future Thinking
- Where
- United States
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- State University of New York at Buffalo
Fatigue, Unspecified Adult Solid Tumor, Protocol Specific
Levocarnitine in Treating Fatigue in Cancer Patients
RATIONALE: Levocarnitine may help improve energy levels in cancer patients. PURPOSE: This randomized phase III trial is studying how well levocarnitine works compared to a placebo in treating fatigue in cancer patients.
- Trial name
- NCT00091169
- Testing
- levocarnitine
- Where
- 116 sites in United States
- Volunteers
- 376 people
- Sponsor
- ECOG-ACRIN Cancer Research Group
Binge-Eating Disorder, Obesity
Behavioral and Pharmacologic Treatment of Binge Eating and Obesity: Maintenance Therapy
This study will test the effectiveness and relative efficacy of naltrexone/bupropion medication as a maintenance therapy for the treatment of binge eating disorder (BED) in patients with obesity.
- Trial name
- NCT03047005
- Testing
- NB medication (Naltrexone Bupropion combination)
- Where
- United States
- Volunteers
- 68 people
- Sponsor
- Yale University
Castration-resistant Prostate Cancer, Androgen Deprivation Therapy
Home-based Exercise Intervention for Patients With Metastatic Prostate Cancer
This single arm, multi-site pilot study aims to evaluate the feasibility of recruiting and adherence to a 12 week home-based exercise intervention to be conducted in men with metastatic castration resistant prostate cancer…
- Trial name
- NCT03672396
- Testing
- Home-based exercise
- Where
- 2 sites in United States
- Volunteers
- 22 people
- Sponsor
- UNC Lineberger Comprehensive Cancer Center
Psychological Stress
Pandemic Acceptance and Commitment Therapy (Pan-ACT): Telehealth Delivery With Older Veterans
Older adults have been disproportionately impacted and distressed by the novel coronavirus (COVID-19) pandemic. Social distancing and stay-at-home orders have increased older adults' risk of social isolation and loneliness that…
- Trial name
- Pan-ACT (NCT05433662)
- Testing
- Pandemic Acceptance and Commitment Therapy (Pan-ACT)
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- VA Office of Research and Development
Systemic Lupus Erythematosus
Exercise and Arterial Stiffness in Systemic Lupus Erythematosus
Patients with Systemic Lupus Erythematosus (SLE) have increased arterial stiffness, which leads to cardiovascular diseases (CVD) of arteriosclerotic origin, which are the main cause of mortality in these patients.
- Trial name
- EJERCITALES (NCT03107442)
- Testing
- Aerobic exercise
- Where
- Spain
- Volunteers
- 58 people
- Sponsor
- Fundación Pública Andaluza para la Investigación Biomédica Andalucía Oriental
Suicidal Ideation
The Effect of Ketamine on the Length of Hospital Stay of Patients Hospitalized With Suicidal Ideation.
This study will evaluate the effect of ketamine on the treatment of patients hospitalized with suicidal thoughts. Half of the patients will receive one dose of ketamine in the vein. The other half will receive a placebo.
- Trial name
- NCT02997722
- Testing
- Ketamine, Normal Saline
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Allen Richert
Perinatal Depression, Post Partum Depression
Characterizing the Neural Substrates of Irritability in Women: an Experimental Neuroendocrine Model
The proposed study involves experimentally manipulating reproductive hormones in nonpregnant, euthymic women to create a scaled down version of the changes that occur during pregnancy and the postpartum period.
- Conditions
- Perinatal Depression, Post Partum Depression, Depression, Postpartum, Depression
- Trial name
- NCT04051320
- Testing
- Leuprolide Acetate 3.75 MG/ML, Estradiol 2 Mg tablet, Micronized progesterone
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
ADHD, Attention Deficit Hyperactivity Disorder
Phase 3 Efficacy and Safety Fixed-Dose Study in Pediatrics (6-17) With ADHD Using CTx-1301
A Phase 3, randomized, double-blind, placebo-controlled, multi-center, fixed-dose, parallel-group efficacy and safety study in a pediatric population (6-17) with Attention-Deficit/Hyperactivity Disorder (ADHD) using CTx-1301…
- Conditions
- ADHD, Attention Deficit Hyperactivity Disorder, ADHD - Combined Type, Attention Deficit Hyperactivity Disorder Combined
- Trial name
- NCT05286762
- Testing
- CTx-1301-Dexmethylphenidate 12.5 mg (titration only), CTx-1301-Dexmethylphenidate 18.75mg (randomized fixed dose), CTx-1301-Dexmethylphenidate 25mg (randomized fixed dose)
- Where
- 24 sites in United States
- Volunteers
- 103 people
- Sponsor
- Cingulate Therapeutics
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