Clinical trials: Behavioural Disorder
Smoking Cessation, Psychiatric Illness
Reducing Cardiovascular Disease by Combining Smoking Cessation Pharmacotherapy and Behavioural Counseling
Research Aims The aims of this research study are: 1. To determine which of the following three smoking cessation medications is most effective in achieving cessation: Nicotine Patch Nicotine Patch + gum or inhaler Varenicline…
- Trial name
- RW (NCT01623505)
- Testing
- Champix, Transdermal Nicoderm patch combined with gum or inhaler, Transdermal Nicoderm patch
- Where
- Canada
- Volunteers
- 738 people, healthy volunteers welcome
- Sponsor
- Ottawa Heart Institute Research Corporation
Parkinson Disease, Idiopathic, REM Sleep Behavior Disorder
Parkinson's Disease Biomarker Study
The primary objective of this study is to determine whether data acquired from a remote monitoring approach can reliably identify and track motor symptoms in prodromal PD and clinical PD.
- Trial name
- PDBS (NCT06812702)
- Testing
- Observational, Skin Biopsy
- Where
- 4 sites in Canada
- Volunteers
- 230 people, healthy volunteers welcome
- Sponsor
- Ronald Postuma
ADHD
Virtual Reality a Novel Screening and Treatment Aid in Attention Deficit Disorder
Using a virtual reality program in screening and treatment of ADHD.
- Trial name
- NCT00364702
- Testing
- methylphenidate
- Where
- Israel
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Shaare Zedek Medical Center
Attention Deficit Hyperactivity Disorder (ADHD)
Brain Activity in Adults With ADHD During Neuropsychological Tasks
The aim of the study is to investigate the response on cognitive testing of healthy persons compared to adults with or without medication against ADHD.
- Trial name
- NCT02578342
- Testing
- MRI
- Where
- Switzerland
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Kantonsspital Aarau
Dementia, Depression
Pilot Study to Examine Health Effects of Daylight Exposure on Dementia Patients
This study is designed to test the hypothesis that an intervention increasing exposure to daylight indoors will reduce depression and other neuropsychiatric symptoms among people living with dementia in long term care facilities.
- Conditions
- Dementia, Depression, Behavior Disorders
- Trial name
- NCT03483896
- Testing
- Daylight Intervention
- Where
- 8 sites in United States
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Oppositional Defiant Disorder
Preschool First Step to Success: An Efficacy Replication Study
The purpose of this research is to conduct a Goal 3 efficacy study to replicate the positive effects of the preschool version of the First Step intervention- Preschool First Step (PFS)-in improving social/behavioral and academic…
- Trial name
- PFS2 (NCT03729154)
- Testing
- First Step
- Volunteers
- 162 people, healthy volunteers welcome
- Sponsor
- Oregon Research Institute
Attention Deficit Hyperactivity Disorder (ADHD)
The Effectiveness of Aerobic Exercise in the Treatment of Adults With Attention Deficit Hyperactivity Disorder (ADHD)
The purpose of this project is to evaluate the effectiveness of a structured aerobic exercise intervention for adults with Attention-Deficit/Hyperactivity Disorder (ADHD) with and without medication and compare it to medication…
- Trial name
- NCT02788851
- Testing
- Methylphenidate compounds and /or Amphetamine compounds and/or Strattera or Guanfacine, Aerobic Exercise
- Where
- Canada
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Child Behavior Disorders, Child Mental Disorder
Epidemiology of Psychiatric Disorders in Children and Adolescent at Egypt
Pediatric, developmental and mental health problems are more common than renal, cardiac and renal problems. Compartmental problems were often conceptualised across two broad spectrums: internalising intrapersonal problems like…
- Conditions
- Child Behavior Disorders, Child Mental Disorder, Adolescent Behaviour Disorder
- Trial name
- NCT04762394
- Testing
- The Child Behavior Checklist (CBCL),
- Where
- Egypt
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Assiut University
Diabetes Mellitus, Type 1
Improving HbA1c Levels Through Behavioural Change of Diabetes Self-management Assisted by the LovedBy Mobile Application for Young Adults and Adolescents With Type 1 Diabetes
Young people (16-25) with type-1 diabetes have historically struggled with managing their condition. Typically, the average HbA1c levels are significantly higher and as such, the risk of long term complications tend to be far…
- Trial name
- LBY-T1 (NCT05217953)
- Testing
- LovedBy App
- Where
- United Kingdom
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Manchester University NHS Foundation Trust
Healthy Adult Participants
Trial to Demonstrate the Equivalence of Two Different Strengths of Oral Centanafadine Capsules in Healthy Subjects
The purpose of this study is to demonstrate dose strength equivalence of 2 × 164.4 milligrams (mg) centanafadine (CTN) once daily (QD) extended-release (XR) capsules to a 1 × 328.8 mg centanafadine QD XR capsule in healthy adult…
- Trial name
- NCT07486895
- Testing
- Centanafadine
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Otsuka Pharmaceutical Development & Commercialization, Inc.
Obesity
Impact of Employee Wellness Programme
The introduction of a wellness programme for workers employed in a clothing factory will improve quality of life, pain, attendance at work and levels of physical activity.
- Trial name
- NCT01625039
- Testing
- Employee wellness programme, Comparator (Once off educational session and educational materials)
- Where
- South Africa
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Cape Town
ADHD - Attention Deficit Disorder With Hyperactivity, Autism Spectrum Disorder (ASD)
Biomarkers of ASD/ADHD and Factors Affecting Anxiety and Depression in Children and Young Adults
The PUREMIND OS1/OS2 study is a multinational, prospective, longitudinal observational study designed to identify early neurophysiological, biological, environmental, and psychosocial markers associated with neurodevelopmental…
- Conditions
- ADHD - Attention Deficit Disorder With Hyperactivity, Autism Spectrum Disorder (ASD), Developmental Coordination Disorder (DCD)
- Trial name
- PUREMIND-OS (NCT07570381)
- Where
- United Kingdom
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- University of Exeter
Lifestyle-related Condition
Obesity Pathway Intervention Among Overweight and Obese Adults at Primary Care Centers in Hail, Saudi Arabia
The goal of this pragmatic trial is to test the benefit of using dietary advice and health coaching for physical activities for obese and overweight in lowering body weight and making them lead a healthy lifestyle.
- Trial name
- Telehealth (NCT05654337)
- Testing
- Expert health counseling
- Where
- Saudi Arabia
- Volunteers
- 440 people, healthy volunteers welcome
- Sponsor
- The New Model of Care, Hail Health Cluster
Insomnia
Online COgnitive Behavioural Therapy for Sleep and Mental Health for Older Adults With Insomnia and Subjective Cognitive Complaints
The goal of this randomized controlled clinical trial is to assess a novel cognitive-behavioral program for sleep and mental health using a multidomain web platform (eCBTi+) in participants with insomnia and subjective cognitive…
- Trial name
- e-COSMOS (NCT06032377)
- Testing
- cognitive behavioral therapy for sleep, anxiety, and depression, education about healthy nutrition habits and communication in older age
- Where
- 2 sites in Canada
- Volunteers
- 275 people, healthy volunteers welcome
- Sponsor
- Centre de Recherche de l'Institut Universitaire de Geriatrie de Montreal
Anxiety, Pregnancy Related
MoodUP in Improving Psychological Outcomes Among Perinatal Women
Dramatic physiological, psychological, and social changes during the antenatal period may significantly affect a woman's psychosocial and physical conditions, thereby resulting in stress, anxiety, and depressive symptoms.
- Conditions
- Anxiety, Pregnancy Related, Perinatal Depression, Prenatal Stress
- Trial name
- NCT03970057
- Testing
- Internet-based Cognitive Behavioural Therapy, Usual Care
- Where
- Singapore
- Volunteers
- 368 people, healthy volunteers welcome
- Sponsor
- National University of Singapore
ADHD
An Evaluation of Neurofeedback Efficacy in Adults With ADHD
The primary objective of this study is to evaluate the effectiveness of neurofeedback training (NFB) on objective measurements of attention in young adults with ADHD.
- Trial name
- NCT01852357
- Testing
- Neurofeedback
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Wilmington
Oppositional Defiant Disorder, Conduct Disorder
Resources to Enhance the Adjustment of Children (REACH)
This continuation study evaluates the long-term outcomes of multimodal, modular interventions with early-onset behavior disordered children and innovative methods to promote the maintenance and extension of treatment effects…
- Conditions
- Oppositional Defiant Disorder, Conduct Disorder, Attention Deficit Hyperactivity Disorder
- Trial name
- REACH (NCT00820001)
- Testing
- Booster Treatment, No-Booster, No intervention
- Where
- 2 sites in United States
- Volunteers
- 254 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Attention Deficit Hyperactivity Disorder
Adults With Attention Deficit Hyperactivity Disorder (ADHD): Validation of a Clinical Interview and Screening Instruments in French
ADHD is a neurodevelopmental disorder that affects about 5% of school-age children and 3.5% of adults worldwide. This condition is under-recognised in France and other European countries and, therefore, under-diagnosed.
- Trial name
- NCT01553695
- Testing
- questionary
- Where
- France
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Nice
Attention Deficit Hyperactivity Disorder (ADHD), Binge-Eating Disorder Disorder
Study of the What the Body Does to the Drug in Subjects With Mild, Moderate, and Severe Liver Dysfunction
Study of the what the body does to the drug in subjects with mild, moderate, and sever liver dysfunction (not working properly)
- Trial name
- NCT02795637
- Testing
- dasotraline
- Where
- 5 sites in United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Sumitomo Pharma America, Inc.
Psychomotor Agitation, Behavioral Disorder
Clinical Trial of Peer Support in the ED (PCORI)
The purpose of this study is to conduct a clinical trial that tests the acceptability, fidelity, and feasibility of a peer support modified intervention for agitation management within the emergency department.
- Trial name
- NCT06556069
- Testing
- Peer-Support Enhanced Agitation Code Team (PACT)
- Where
- United States
- Volunteers
- 57,870 people, healthy volunteers welcome
- Sponsor
- Yale University