Clinical trials: Behavioural Disturbances
Child Behavior Problem
Family STEPS: Family Check-Up+
Interventions that promote safe, stable, and nurturing relationships between caregivers and children are key to improving healthy family relationships, reducing child socioemotional and behaviour problems, and preventing child…
- Trial name
- FamilySTEPS (NCT07433361)
- Testing
- Family Check Up
- Where
- Canada
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- McMaster University
Hypersialorrhea (Excessive Salivation), Psychiatric Disorders
Chewing Gum as a Therapeutic Intervention for the Management of Hypersalivation
Psychiatric disorders often require specific treatments, usually involving medications called psychotropic drugs. While effective, these medications can cause significant side effects.
- Trial name
- Chew Daily (NCT07158359)
- Testing
- chewing gum mastication
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier de Cadillac
Attention Deficit/Hyperactivity Disorder
Strongest Families (Formerly Family Help Program): Pediatric Attention Deficit/Hyperactivity Disorder
The purpose of the Strongest Families (formerly Family Help Program)is to evaluate the effectiveness of the Strongest Families distance intervention compared to usual or standard care that is typically provided to children with…
- Trial name
- FHPADHD (NCT00267605)
- Testing
- FHPADHD, ADHD Standard Care
- Where
- Canada
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- IWK Health Centre
Post Traumatic Stress Disorder, Alcohol Use Disorder
FAAH Availability in Psychiatric Disorders: A PET Study
The aim of the present study is to examine Fatty Acid Amide Hydrolase (FAAH) availability in humans, including healthy individuals and across a spectrum of psychiatric disorders in which alterations in the endocannabinoid system…
- Conditions
- Post Traumatic Stress Disorder, Alcohol Use Disorder, Psychosis
- Trial name
- NCT04404712
- Testing
- [11C]MK-3168
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Yale University
Spinal Muscular Atrophy, Amyotrophic Lateral Sclerosis
Phase II Study of Leuprolide and Testosterone for Men With Kennedy's Disease or Other Motor Neuron Disease
OBJECTIVES: I. Evaluate the effects of androgen suppression with leuprolide and androgen replacement with testosterone enanthate on muscle strength in men with Kennedy's disease or other motor neuron disease.
- Conditions
- Spinal Muscular Atrophy, Amyotrophic Lateral Sclerosis, Spinobulbar Muscular Atrophy
- Trial name
- NCT00004771
- Testing
- leuprolide, testosterone
- Volunteers
- 40 people
- Sponsor
- National Center for Research Resources (NCRR)
Behavioral Symptoms, Autistic Disorder
Study of Aripiprazole in the Treatment of Children and Adolescents With Autistic Disorder (AD)
This study will compare the effectiveness (how well the drug works) of aripiprazole with placebo (fixed dose) in reducing serious behavioral problems in children and adolescents with a diagnosis of autistic disorder (AD).
- Trial name
- NCT00337571
- Testing
- Aripiprazole
- Where
- 31 sites in United States
- Volunteers
- 218 people
- Sponsor
- Otsuka Pharmaceutical Development & Commercialization, Inc.
Metabolic Syndrome (MetS), Psychiatric Disorders
The Impact of the Mediterranean Diet on Anthropometric Indices, Lipid Profiles, Energy Metabolism Signaling Proteins and Inflammatory Cytokines in Psychiatric Patients With Metabolic Syndrome
Background: Dietary modifications, like changing macronutrient distribution and improving food quality, are the main therapeutic approaches for managing oxidative stress, inflammation, and metabolic syndrome.
- Conditions
- Metabolic Syndrome (MetS), Psychiatric Disorders, Mediterranean Diet, Inflammatory Cytokines
- Trial name
- NCT07164014
- Testing
- Mediterranean diet, Hospital diet
- Where
- Saudi Arabia
- Volunteers
- 144 people
- Sponsor
- King Saud University
Problem Behavior
Behavioral Economics and Communication
This project examines mechanisms to address two significant challenges present in communication-based behavioral interventions for individuals with autism and comorbid severe destructive behavior (SDB): (a) inflexible…
- Trial name
- NCT05918393
- Testing
- functional communication training
- Where
- United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- State University of New York - Upstate Medical University
Delivery of Health Care
Evaluation of a Cross-sectional Coordinated, Severity Stepped, Evidence-based Care Model for Mental Disorders
This study evaluates a cross sectional, severity stepped, evidence-based care model for patients with mental disorders (RECOVER).
- Trial name
- RECOVER (NCT03459664)
- Testing
- RECOVER, Treatment as usual
- Where
- Germany
- Volunteers
- 905 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Prader-Willi Syndrome
A Study of Pitolisant in Patients With Prader-Willi Syndrome
This is a Phase 3, randomized, double-blind, placebo-controlled, multicenter, global clinical study to assess the efficacy and safety of pitolisant in patients living with Prader-Willi syndrome.
- Trial name
- NCT06366464
- Testing
- Pitolisant tablet
- Where
- 57 sites in United States, Australia and 11 more
- Volunteers
- 134 people
- Sponsor
- Harmony Biosciences Management, Inc.
Problem Behavior
Effects of Good Behavior Game in a Swedish Sample
This project seeks to study the impact of Good Behavior Game (GBG), a behavior management program, on classroom environment and problem behavior in K-3 classrooms.
- Trial name
- NCT05794893
- Testing
- Good Behavior Game
- Where
- 5 sites in Sweden
- Volunteers
- 44 people
- Sponsor
- Region Skane
Pregnancy
Prevalence of Psychiatric Disorders During Pregnancy at 2nd Trimester Ultrasound: a Feasibility Study in the General Population
Young women represent a population at risk of psychiatric disorders, the first signs of which often appear between the ages of 15 and 25. Psychiatric disorders are a major source of disability and healthcare costs.
- Trial name
- GROUP (NCT06297252)
- Testing
- standardized clinical psychiatric evaluations, self-administered psychiatric questionnaire assessments, blood sampling
- Where
- 2 sites in France
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Skin Restricted Lupus, Psychiatric Disorders
Role of Inflammation in Psychiatric Disorders in Patients With Cutaneous Lupus
The purpose of this study is to determine the role of inflammation in the high prevalence of psychiatric disorders in skin-restricted lupus (SRL) patients. SRL is an inflammatory disease.
- Trial name
- RIP-LC (NCT03125083)
- Testing
- Biological dosage from plasma
- Where
- France
- Volunteers
- 40 people
- Sponsor
- University Hospital, Clermont-Ferrand
Psychomotor Retardation, Psychomotor Slowing
Transcranial Magnetic Stimulation (TMS) for Motor Symptoms in Psychiatric Disorders
Psychomotor slowing may occur in major psychiatric disorders, such as major depressive disorders or schizophrenia spectrum disorders. It refers to slowing of fine motor skills, motor planning and gross motor behavior.
- Conditions
- Psychomotor Retardation, Psychomotor Slowing, Schizophrenia and Related Disorders, Major Depressive Disorder
- Trial name
- NCT03275766
- Testing
- DLPFC facilitatory, SMA inhibitory, SMA facilitatory
- Where
- Switzerland
- Volunteers
- 45 people
- Sponsor
- University of Bern
Adolescent Behavior Problem, Mental Health Wellness 1
Future Leaders Program: Testing a Youth Leadership, Engagement, and Mindfulness Program
The current study tests the feasibility and effectiveness of a youth intervention designed to provide meaningful leadership opportunities through the acquisition of leadership skills as well as mindfulness practice, LEAP…
- Trial name
- FLP (NCT06736522)
- Testing
- Leadership, Engagement, and youth Action Program with Mindfulness, EnvisionIT
- Where
- 3 sites in United States
- Volunteers
- 504 people, healthy volunteers welcome
- Sponsor
- Boston University Charles River Campus
Behavioral Symptom, Preschool Child
Cognitive-Based Behavior Change Training Program
This study will be conducted to determine the effects of the Parent Education Program Based on the Cognitive Development of the Child, which is applied to the parents of preschool children with behavioral problems, on the…
- Conditions
- Behavioral Symptom, Preschool Child, Parent, Parent-Child Relations
- Trial name
- NCT06985667
- Testing
- Cognitive-Based Behavior Change Training Program
- Where
- Turkey (Türkiye)
- Volunteers
- 44 people
- Sponsor
- Uskudar University
Behavior, Child, Parenting
The Effect and Experience of the Parental Program AFFEKT
This project is the first to evaluate the effect and experience of the parent program AFFEKT, through a randomized controlled trial and qualitative study, within primary health care.
- Conditions
- Behavior, Child, Parenting, Parent-Child Relations, Stress
- Trial name
- NCT05983705
- Testing
- AFFEKT - a manual based brief parent program for parents of children (aged 6-12 years) with externalizing behaviors.
- Where
- Sweden
- Volunteers
- 198 people
- Sponsor
- Göteborg University
Behavioral Problem, Irritable Mood
Stop, Focus, Plan, and Change: Predicting Parent and Child Responses to a Brief, Telehealth Parent Training
This study will look at who does not improve after doing a behavioral parent training program briefly through telehealth. It will also study ways to make the intervention better for those that do not improve.
- Conditions
- Behavioral Problem, Irritable Mood, Parenting, Stress
- Trial name
- NCT06505980
- Testing
- Brief Behavioral Parenting Program
- Where
- United States
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Emotional Problems, Behavior Problems
A Targeted Prevention Approach to Reducing Child Emotional and Behaviour Problems
The purpose of the study is to evaluate the first Canadian implementation project of the Family Check up (FCU), an evidence-based prevention and early intervention model that engages families and communities in reducing the…
- Trial name
- NCT02800603
- Testing
- Family Check Up
- Where
- Canada
- Volunteers
- 207 people
- Sponsor
- McMaster University
Depressive Symptoms, Trauma, Psychological
Improving Mental Health and School Performance in Urban Eighth Graders
This study assesses: (1) the impact of the Relax, Be Aware, Do a Personal Rating (RAP) Club, a school-based prevention program for urban eighth graders, on students' emotional functioning and education outcomes; (2) potential…
- Conditions
- Depressive Symptoms, Trauma, Psychological, Disruptive Behavior
- Trial name
- NCT03906682
- Testing
- RAP Club, Healthy Topics
- Where
- United States
- Volunteers
- 615 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins Bloomberg School of Public Health