Clinical trials: Benign Breast Tumors
Breast Cancer
Role of Cytochrome P450 2D6 (CYP2D6) *4 Polymorphism,in Malignant Breast Diseases
The aim of our study is to investigate the potential role of the CYP2D6*4 polymorphism in breast cancer and furthermore to assess the role of oxidative stress, antioxidant capacity and ferretin in pathogenesis of breast cancer in…
- Trial name
- NCT00539422
- Testing
- pcr and serum markers for breast cancer
- Where
- Egypt
- Volunteers
- healthy volunteers welcome
- Sponsor
- Mansoura University
Breast Cancer, Benign Breast Disease
Evaluating Scaleup of an Adapted Breast Cancer Early Diagnosis Program in Rwanda
Breast cancer incidence is increasing in low- and middle-income countries (LMICs) and breast cancer mortality is high in these regions largely due to late stage diagnoses.
- Conditions
- Breast Cancer, Benign Breast Disease, Cervix Cancer
- Trial name
- NCT05364138
- Where
- Rwanda
- Volunteers
- 2,357 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Benign Breast Lesions, Malignant Breast Tumours
Photo-Acoustic and Ultrasonographic Mammoscope
The aim of this study is to evaluate the negative predictive value of the Photo Acoustic Imager 3+ (PAM3+) in the detection of female breast lesions (malignant and benign)in an outpatient setting.
- Trial name
- PAUS (NCT07492589)
- Testing
- Photo-Acoustic Mammoscope Imager 3+
- Where
- Netherlands
- Volunteers
- 180 people
- Sponsor
- Franciscus Gasthuis & Vlietland (Hospital)
Breast Cancer, Nipple Discharge
A Study on Combined Low-pass Whole-genome and Methylome Testing of Bloody Nipple Discharge Specimens for Benign-Malignant Differentiation.
This is a prospective, single-center diagnostic study testing whether a new, minimally invasive analysis of nipple fluid can distinguish benign from malignant causes of pathologic nipple discharge.
- Trial name
- NCT07250204
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Hubei Cancer Hospital
Breast Cancer
Nipple Secretion Samples in Detecting Breast Cancer in Patients and Healthy Participants Undergoing Breast Cancer Screening, Breast Diagnostic Studies, or Treatment for Benign Breast Disease
RATIONALE: Diagnostic procedures that measure biomarker levels in nipple section and blood samples, may help in the early detection of breast cancer.
- Trial name
- NCT00813878
- Testing
- protein analysis, protein expression analysis, proteomic profiling
- Where
- United States
- Volunteers
- 126 people
- Sponsor
- City of Hope Medical Center
Pulmonary Coin Lesion, Colon Cancer Liver Metastasis
Optical Detection of Malignancy During Percutaneous Interventions
Investigation of application possibilities of optical spectroscopy within the field of oncology. Optical spectroscopy enables the possibility to specifically differentiate between different (human) tissues.
- Conditions
- Pulmonary Coin Lesion, Colon Cancer Liver Metastasis, Breast Cancer
- Trial name
- NCT01730365
- Testing
- Core biopsy procedure
- Where
- Netherlands
- Volunteers
- 104 people
- Sponsor
- Philips Healthcare
Breast Neoplasm Female, Benign Breast Neoplasm
A Novel Approach in the Evaluation of Breast Masses With Doppler US
In cases with breast masses, Doppler resistive index values will be calculated for the mass and surrounding healthy tissue and the opposite healthy breast tissue, and their effect on distinguishing between benign and malignant…
- Conditions
- Breast Neoplasm Female, Benign Breast Neoplasm, Malign Breast Neoplasm, Doppler Ultrasound Diagnosis
- Trial name
- NCT07465523
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Ahmet Yesildag
Breast Cancer Surgery, Benign Breast Tumors
Analysis of Recurrence of Intraductal Papilloma Treated With Vacuum-assisted Rotary Excision
To study the postoperative recurrence of intraductal papillomas (IDP) treated with ultrasound-guided vacuum-assisted excision (VAE), and to investigate the effect of different lesion characteristics on recurrence.
- Trial name
- IDP (NCT06970561)
- Testing
- enlarged resection
- Where
- China
- Volunteers
- 106 people
- Sponsor
- Wuhan Children's Hospital
Thyroid Tumor, Breast Tumor
Detection of Benign and Malignant Thyroid and Breast Tumors by Fourier Transform Infrared Spectrometry
The purpose of this stage of study is to establish discriminant among healthy tissue, benign and malignant thyroid and breast tumors by fourier transform infrared spectrometry variables.
- Trial name
- NCT01668238
- Where
- China
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- XU Zhi
Breast Cancer, Benign Breast Disease
An Investigation Into Dielectric Assessment of Permittivity and Conductivity in Human Using a Novel Electrical Capacitance Tomography Scanner
The goal of this observational study is to investigate the ability of a the Z-scanner to identify and differentiate cancer and benign lesions from healthy breast tissue based on permittivity.
- Trial name
- DiCECT (NCT06264934)
- Testing
- Breast scan using the Z-scanner
- Where
- United Kingdom
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Zedsen Limited
Benign Breast Conditions; Breast Fibroadenomas
American Breast Laser Ablation Therapy Evaluation
The purpose of this patient tracking program is to monitor long term safety and effectiveness of the Novilase™ device and method in real world application.
- Trial name
- ABLATE (NCT00807924)
- Where
- United States
- Volunteers
- 108 people
- Sponsor
- Novian Health Inc.
Breast Cancer
Collection of FUJIFILM's 3Dimensional Mammograms
This image-acquisition study is designed to acquire the study image data and establish and document the clinical findings for each subject.
- Trial name
- 3DM (NCT01542814)
- Testing
- 3Dimensional Mammography, 2D FFDM
- Where
- 3 sites in United States
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Fujifilm Medical Systems USA, Inc.
Advanced Malignant Neoplasm, Castleman Disease
Bevacizumab and Temsirolimus Alone or in Combination With Valproic Acid or Cetuximab in Treating Patients With Advanced or Metastatic Malignancy or Other Benign Disease
This phase I trial studies the side effects and best dose of bevacizumab and temsirolimus alone or in combination with valproic acid or cetuximab in treating patients with a malignancy that has spread to other places in the body…
- Conditions
- Advanced Malignant Neoplasm, Castleman Disease, Digestive System Carcinoma, Erdheim-Chester Disease
- Trial name
- NCT01552434
- Testing
- Bevacizumab, Cetuximab, Laboratory Biomarker Analysis
- Where
- United States
- Volunteers
- 154 people
- Sponsor
- M.D. Anderson Cancer Center
Breast Cancer
VisR Ultrasound for Noninvasively Interrogating Stromal Collagen Organization in Women as a Breast Cancer Biomarker: Evaluation of Anisotropy in Cancer Patients
Purpose: This study will evaluate how measurements of tissue stiffness, viscosity, and anisotropy using non-invasive ultrasound imaging correlate with breast tumor malignancy and response to chemotherapy.
- Trial name
- NCT06878547
- Testing
- Ultrasound
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- UNC Lineberger Comprehensive Cancer Center
Breast Cancer
NIR Fluorescent Molecular Probe for the Identification of Breast Tissue
Accurate evaluation of tumor boundaries in breast-conserving surgery is critical to reducing the second operation of patients. Near-infrared (NIR) fluorescence imaging using molecular agents has shown promise for in situ imaging…
- Trial name
- NIR (NCT05708144)
- Testing
- ICG-SG incubation solution
- Where
- China
- Volunteers
- 26 people
- Sponsor
- Xiang'an Hospital of Xiamen University
Chronic Liver Disease, Thyroid Disease
The Development of Quantitative Ultrasound Imaging Software Platform
The goal of this observational study is to compare the image differences between conventional ultrasound and artificial intelligence-based ultrasound software in conscious adults.
- Conditions
- Chronic Liver Disease, Thyroid Disease, Benign Breast Disease, Malignant Breast Neoplasm
- Trial name
- NCT05836246
- Where
- South Korea
- Volunteers
- 196 people
- Sponsor
- Seoul National University Bundang Hospital
Breast Disease, Benign Breast Disease
Effectiveness Validation of CELBREA® in Symptomatic Women or With Diagnostic Doubt of Breast Pathology (DETECT-BH)
This is an observational, prospective, and transversal study, designed to evaluate the effectiveness of CELBREA® in women from the local community coming to consult at the Breast Pathology Unit of La Paz Hospital (Madrid, Spain)…
- Conditions
- Breast Disease, Benign Breast Disease, Breast Cancer
- Trial name
- DETECT-BH (NCT05857111)
- Testing
- Celbrea
- Where
- Spain
- Volunteers
- 255 people
- Sponsor
- Jose Ignacio Sánchez
Breast Cancer Female
Identification of Benign and Malignant Breast Nodules Using Ultrasound-modulated Optical Tomography: A Multicenter Study
Ultrasonic light scattering imaging is a new functional imaging technology that combines traditional B-mode ultrasound imaging and light scattering tomography (DOT).
- Trial name
- NCT06468566
- Testing
- Ultrasound light scattering imaging equipment
- Where
- China
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Xin-Wu Cui
Diagnosis, Axilla; Breast
Benign-Malign Differentiation of Axillary Lymph Nodes: The Role Of Superb Microvascular Imaging
102 patients who have suspicious ALNs were included in our prospective study, which was approved by a tertiary health care facility ethics committee.
- Trial name
- NCT05927727
- Testing
- Ultrasound and biyopsy
- Where
- Turkey (Türkiye)
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Ankara Education and Research Hospital
Breast Cancer
Physical Activity, Proliferation and Immune Markers in Benign Breast Tissue
This research study is evaluating the effect of exercise on markers in breast tissue and blood of premenopausal women who have been found to have dense breast tissue on mammogram.
- Trial name
- NCT03657628
- Testing
- Exercise Intervention
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Dana-Farber Cancer Institute