Clinical trials: Benign Gynecologic Neoplasm
Hysterectomy, Minimal Invasive Surgery
Comparative Study of LAVH and Minilaparotomy Hysterectomy
Minilaparotomy hysterectomy (MLH) relies on the simplicity of traditional open technique of abdominal hysterectomy, imparts cosmesis and faster recovery of laparoscopic hysterectomy yet avoids the long learning curve, cost of…
- Conditions
- Hysterectomy, Minimal Invasive Surgery, Benign Gynecologic Neoplasm
- Trial name
- LAVH (NCT03548831)
- Volunteers
- 52 people
- Sponsor
- Manipal University
Advanced Malignant Neoplasm, Castleman Disease
Bevacizumab and Temsirolimus Alone or in Combination With Valproic Acid or Cetuximab in Treating Patients With Advanced or Metastatic Malignancy or Other Benign Disease
This phase I trial studies the side effects and best dose of bevacizumab and temsirolimus alone or in combination with valproic acid or cetuximab in treating patients with a malignancy that has spread to other places in the body…
- Conditions
- Advanced Malignant Neoplasm, Castleman Disease, Digestive System Carcinoma, Erdheim-Chester Disease
- Trial name
- NCT01552434
- Testing
- Bevacizumab, Cetuximab, Laboratory Biomarker Analysis
- Where
- United States
- Volunteers
- 154 people
- Sponsor
- M.D. Anderson Cancer Center
Uterine Fibroid
UA Versus UAE in Treatment of Fibroids
Study objective: To prove that Ulipristal acetate is an effective line of management for uterine fibroids by causing a significant decline in fibroid volumes resulting in a substantial relief of fibroid-related symptoms, and to…
- Trial name
- NCT04832906
- Testing
- Ulipristal Oral Tablet, Uterine artery embolization
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Ain Shams Maternity Hospital
Benign Gynecologic Neoplasm
Postoperative Analgesic Efficacy of Continuous Wound Infusion After Laparoscopy
Studies evaluating the effectiveness of continuous wound infusion (CWI) to manage postoperative pain following laparoscopy are markedly lacking.
- Trial name
- PAIN (NCT03645304)
- Testing
- Ropivacaine, 0.9% saline group, ON-Q Painbuster Silver Soaker
- Where
- South Korea
- Volunteers
- 66 people
- Sponsor
- Kangbuk Samsung Hospital
Benign Gynecologic Neoplasm
Effects of Tissue Sealers on Minor Laparoscopic Procedures Between Obstetrics and Gynecology Residents
The kind of equipment used during laparoscopic surgery may have an effect on how quickly resident surgeons improve their skills.
- Trial name
- NCT05710601
- Testing
- Laparoscopy
- Where
- Italy
- Volunteers
- 80 people
- Sponsor
- University of Campania Luigi Vanvitelli
Colorectal Cancer, Urologic Cancer
Fluid Challenge and Plasma Volume, During Surgery
A short bolus infusion of fluid, called "fluid challenge" is commonly recommended for fluid treatment during longer surgery. However a prolonged increase of the blood volume is a prerequisite to recommend the technique.
- Conditions
- Colorectal Cancer, Urologic Cancer, Gynecologic Cancer, Colorectal Disorders
- Trial name
- FC-VE (NCT05726136)
- Testing
- acetated Ringers, albumin 5%, albumin 20%
- Where
- Sweden
- Volunteers
- 60 people
- Sponsor
- Joachim Zdolsek
Gynecologic Tumor
The Value of Advanced MR Imaging in Gynecological Tumors and Benign Uterine Fibroids
This research is being done to test new MRI methods called Magnetic Resonance Fingerprinting and Q-space Trajectory Imaging in gynecological abnormalities.
- Trial name
- NCT03993210
- Testing
- Magnetic Resonance Fingerprinting (MRF), Q-space Trajectory Imaging (QTI), Magnetic Resonance Imaging Machine (MRI)
- Where
- 2 sites in United States
- Volunteers
- 1 people
- Sponsor
- Dana-Farber Cancer Institute
Fibroid Uterus, Metrorrhagia
A Randomized Study Comparing Subtotal vs Total Hysterectomy Long Term Outcomes
The goal of this randomized clinical trial is to assess the outcomes of total laparoscopic hysterectomy vs subtotal laparoscopic hysterectomy + mini-laparotomy for uterine extraction for benign gynecological conditions in terms…
- Conditions
- Fibroid Uterus, Metrorrhagia, Adenomyosis, Benign Gynecologic Neoplasm
- Trial name
- STORY (NCT06802198)
- Testing
- total hysterectomy, subtotal hysterectomy
- Where
- Italy
- Volunteers
- 500 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Benign Female Reproductive System Neoplasm
Does Less Trendelenburg Make a Difference in Robotic Assisted Gynecological Procedures?
Patient/Population: Women over the age of 18, who are not pregnant and are undergoing benign, robotic-assisted gynecologic procedures at Lutheran General Hospital.
- Trial name
- NCT02728999
- Testing
- Steep Trendelenburg, Decreased Trendelenburg
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Wake Forest University Health Sciences
Benign Female Reproductive System Neoplasm
Efficacy and Safety of Parecoxib on Morphine Patient-controlled Epidural Analgesia (PCEA) After Gynecologic Surgery
The purpose of this study is to determine the effects of parecoxib in combination with epidural morphine in providing analgesia for patients undergoing gynecological surgery.
- Trial name
- PCEA (NCT01566669)
- Testing
- Parecoxib Sodium, Normal saline
- Where
- China
- Volunteers
- 294 people
- Sponsor
- Liu Weifeng
Benign Gynecologic Neoplasm
Efficacy and Safety Evaluation of Vi-sealer
This study's primary goal is to compare the efficacy and safety of the novel advanced hemostatic device(AHD), Vi-Sealer, with conventional AHDs in laparoscopic total hysterectomy for patients with benign gynecologic neoplasm.
- Trial name
- NCT05629611
- Testing
- Vi-Sealer, Ligasure, Other AHD
- Where
- South Korea
- Volunteers
- 280 people
- Sponsor
- Hyun Park
Ovarian Cancer, Endometrial Cancer
Biomarkers for Gynecologic Cancer
A novel blood metabolic biomarker, AminoIndexTM (gynecological), was developed for gynecological cancers from over 400 Japanese patient's plasma free amino acid profiles (PFAAs) by a rapid and sensitive LC-MS (Liquid…
- Conditions
- Ovarian Cancer, Endometrial Cancer, Benign Gynecological Disease
- Trial name
- NCT02178462
- Where
- United States
- Volunteers
- 153 people, healthy volunteers welcome
- Sponsor
- Ajinomoto Co., Inc.
Benign Gynecologic Neoplasm
Does Simethicone Improve Operative Field in Gynecological Operations
Mechanical bowel preparation aims to decrease the volume fecal content in the colon, which thereby decreases the total colony count of bacteria, thus, decreasing peritoneal contamination in case of bowel injury, improving the…
- Trial name
- NCT03009604
- Testing
- Simethicone, Enema
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Assiut University