Clinical trials: Benign Hyperplasia of Prostate
Benign Prostatic Hyperplasia, Lower Urinary Tract Symptoms
AQUABEAM® Robotic System and Ultrasound Accessories
Lower urinary symptoms (LUTS) affect many older men and their frequency and severity increase with age. In the age group between 65 and 79 years the rate of men with moderate and severe LUTS is 20 - 25% (Hunter et al. 1994).
- Trial name
- AQUA (NCT05157529)
- Testing
- AQUABEAM Robotic System, Apogee 2300 digital color doppler ultrasound imaging system
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Lower Urinary Tract Symptoms, Benign Prostatic Hyperplasia
MCS in the Treatment of Lower Urinary Tract Symptoms
The hypothesis of the study is to examine whether MCS-2 is safe and effective in the treatment of lower urinary tract symptoms suggestive of benign prostatic hyperplasia.
- Trial name
- MCS_LUTS (NCT01002417)
- Testing
- MCS-2 15 mg/day, MCS-2 30 mg/day
- Where
- United States
- Volunteers
- 274 people
- Sponsor
- Health Ever Bio-Tech Co., Ltd.
Benign Prostatic Hyperplasia, Prostatitis
2013 Annual National Digital Rectal Exam (DRE) Day Study
We aim to determine the effectiveness of 2013 "Mag paDRE ka" programme in increasing general public awareness on prostate health and promoting prostate health assessment among Filipino males aged 40 or older.
- Conditions
- Benign Prostatic Hyperplasia, Prostatitis, Prostate Cancer
- Trial name
- NCT01886547
- Testing
- Prostate health screening
- Where
- Philippines
- Volunteers
- 925 people, healthy volunteers welcome
- Sponsor
- St. Luke's Medical Center, Philippines
Benign Prostatic Hyperplasia
Local Anesthesia With Schelin Catheter in Rezum Treatment: a Randomized Controlled Trial
In a pilot study, water vapor therapy (RezumTM, Boston Scientific Corporation, Marlborough, MA) was proposed as a minimally invasive procedure for benign prostatic hyperplasia, but often requiring oral ± intravenous sedation or a…
- Trial name
- LOCALVAPOR (NCT06657872)
- Testing
- water vapor therapy under general anesthesia, water vapor therapy under local anesthesia
- Where
- France
- Volunteers
- 24 people
- Sponsor
- Assistance Publique Hopitaux De Marseille
Transurethral Resection of Prostate, Artery Embolization
Clinical Trial to Evaluate the Efficacy and Safety of the Transarterial Supraselective Embolization of the Prostate to Treat the Urinary Symptoms.
The purpose of this study is to determine whether the transarterial supraselective embolization (TSE) is a technique as effective as transurethral resection of the prostate (TURP) for the treatment of lower urinary tract symptoms…
- Conditions
- Transurethral Resection of Prostate, Artery Embolization, Benign Prostatic Hyperplasia, Lower Urinary Tract Symptoms
- Trial name
- NCT01963312
- Testing
- Transarterial Supraselective Embolization of the prostate, Transurethral Resection of the prostate
- Where
- Spain
- Volunteers
- 81 people
- Sponsor
- Fundacion Miguel Servet
Benign Prostatic Hyperplasia
Laser Enucleation of Prostate (LEP) Versus Transurethral Resection of Prostate (TURP)
Benign prostatic hyperplasia (BPH) refers to the proliferation of smooth muscle and epithelial cells of the prostate gland. The enlarged gland has the potential to result in lower urinary tract symptoms (LUTS) secondary to either…
- Trial name
- NCT03062111
- Testing
- ProTouch Laser Enucleation of Prostate (LEP), Transurethral Resection of Prostate (TURP)
- Where
- United States
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- Boston University
Benign Prostatic Hypertrophy
Wolf 24 F vs. Storz 28 F Laser Sheath Size for HoLEP
The purpose of this study is to compare two different types of scopes that can be used for HoLEP. HoLEP is performed through the urethra using a Laser scope to remove obstructing prostate tissue.
- Trial name
- NCT05308017
- Testing
- Richard Wolf 24F Laser scope, Karl Storz 28F Laser Scope
- Where
- United States
- Volunteers
- 152 people
- Sponsor
- Northwestern University
Benign Prostatic Hyperplasia
A Study to Track the Safety of Vesomni in Men in South Korea Treated in Routine Clinical Practice for the Urinary Symptoms of Benign Prostatic Hyperplasia (Enlarged Prostate)
Benign prostatic hyperplasia (BPH), also known as an enlarged prostate, happens more often in men as they age. This condition causes a sudden need to pass urine, which is hard to control.
- Trial name
- NCT07619105
- Testing
- Vesomni
- Volunteers
- 600 people
- Sponsor
- Astellas Pharma Korea, Inc.
Benign Prostate Hyperplasia
Post-Marketing Study Using PROLIEVE® for the Treatment of Benign Prostatic Hyperplasia (BPH)
The primary objective of the post-marketing study is to collect safety and effectiveness data for 5 years on subjects treated with Prolieve®.
- Trial name
- NCT02021032
- Testing
- Prolieve
- Where
- 8 sites in United States
- Volunteers
- 250 people
- Sponsor
- Medifocus, Inc.
Benign Prostatic Hyperplasia
Enhanced Clinical Decisions for Management of Benign Prostatic Hyperplasia Using Patient-Reported Outcomes
The goal of this project is to use newly developed patient-reported outcomes to improve the clinical care of patients with benign prostatic hyperplasia.
- Trial name
- NCT05898932
- Testing
- Medical Management, Surgical Management
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- Northwestern University
Prostate Obstruction, Prostatic Hyperplasia
Bipolar Needlescopic Enucleation Versus Vapoenucleation of BPH
Transurethral resection of the prostate (TURP) is the current standard procedure for men with prostate volume 30-80 gm. In case with large prostate adenoma (>80 g), the resection time required by TURP is associated with increased…
- Conditions
- Prostate Obstruction, Prostatic Hyperplasia, Prostatic Hypertrophy, Benign
- Trial name
- NCT04331301
- Testing
- Bipolar Vapo-Enucleation of the prostate, Bipolar Needlescopic Enucleation of the prostate
- Where
- Egypt
- Volunteers
- 214 people
- Sponsor
- Benha University
Benign Prostatic Hyperplasia, BPH
Phase 3 Evaluation of Re-Injection of NX-1207 for the Treatment of Benign Prostatic Hyperplasia (BPH)(NX02-0022)
This study is designed to demonstrate the safety and efficacy of a second transrectal intraprostatic injection of NX-1207 given to subjects with Benign Prostatic Hyperplasia (BPH) who previously received an injection of NX-1207…
- Conditions
- Benign Prostatic Hyperplasia, BPH, Lower Urinary Tract Symptoms (LUTS), LUTS
- Trial name
- NCT01846793
- Testing
- NX-1207
- Where
- 17 sites in United States
- Volunteers
- 160 people
- Sponsor
- Nymox Corporation
Prostatic Hyperplasia
HoLEP vs mTURP in Management of Benign Prostatic Hyperplasia
To compare the clinical outcome regarding safety and efficacy between Holmium laser enucleation of the prostate and transurethral resection of the prostate in management of benign prostatic hyperplasia.
- Trial name
- NCT04561505
- Testing
- Holmium laser enucleation of prostate, monopolar transurethral resection of prostate
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Ain Shams University
Urinary Tract Infection Bacterial, Benign Prostatic Hyperplasia
Closed-System Bladder Irrigation to Reduce Urinary Tract Infections After Endoscopic Urologic Surgery (IRIS Trial)
This randomized controlled trial evaluates whether a closed-system bladder irrigation device can reduce the incidence of urinary tract infections in patients undergoing endoscopic urologic surgery.
- Conditions
- Urinary Tract Infection Bacterial, Benign Prostatic Hyperplasia, Bladder Cancer
- Trial name
- IRIS (NCT07510685)
- Testing
- Closed-System Bladder Irrigation Flow Switch Device, Standard Bladder Irrigation
- Where
- Italy
- Volunteers
- 240 people
- Sponsor
- University of Pisa
Benign Prostatic Hyperplasia
Safety and Efficacy Study of Botulinum Toxin Type A to Treat Lower Urinary Symptoms Due to Benign Prostatic Hyperplasia
The purpose of this study was to determine the safety and effectiveness of different doses of botulinum toxin Type A in treating lower urinary tract symptoms due to benign prostatic hyperplasia.
- Trial name
- NCT00284518
- Testing
- botulinum toxin Type A, normal saline
- Where
- 11 sites in Australia, Austria and 9 more
- Volunteers
- 380 people
- Sponsor
- Allergan
BPH With Urinary Obstruction With Other Lower Urinary Tract Symptoms
WATER III: Aquablation vs. Transurethral Laser Enucleation of Large Prostates (80 - 180mL) in Benign Prostatic Hyperplasia
Comparative analysis of efficacy and safety of Aquablation (AQUABEAM Robotic System®, PROCEPT BioRobotics, Redwood City, CA, USA) and transurethral laser enucleation as surgical therapy for benign prostatic hyperplasia with large…
- Trial name
- WATER III (NCT04801381)
- Testing
- Aquablation therapy, Transurethral laser enucleation
- Where
- 5 sites in Germany, United Kingdom
- Volunteers
- 202 people
- Sponsor
- University of Bonn
Sexual Dysfunctions in Men With Benign Prostatic Hyperplasia
Clinical Study to Assess the Influence of a Saw Palmetto Preparation in Patients With Benign Prostatic Hyperplasia (BPH) and Sexual Dysfunctions
Assessment in an open trial if a standardized saw palmetto preparation has a positive influence on sexual dysfunctions in patients with BPH and sexual dysfunctions.
- Trial name
- NCT01021267
- Testing
- Saw palmetto berry extract
- Where
- Switzerland
- Volunteers
- 50 people
- Sponsor
- A. Vogel AG
Prostatic Hyperplasia
Prostate Artery Embolization as a Treatment for Benign Prostatic Hyperplasia in Men With Prostates Larger Than 90 Grams
The purpose of the study is to evaluate improvement in symptoms related to benign prostatic hyperplasia (BPH) in men treated with prostate artery embolization (PAE) using Embosphere Microspheres.
- Trial name
- NCT02396420
- Testing
- Embosphere Microspheres
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- South Florida Medical Imaging, PA
Prostate Cancer
Feasibility and Toxicity of Degarelix for Prostate Downsizing Prior to Permanent Seed Prostate Brachytherapy
This study will investigate the efficacy of Degarelix, a Luteinizing Hormone Releasing Hormone (LHRH) antagonist, to reduce prostate volume prior to permanent seed prostate brachytherapy.
- Trial name
- NCT01446991
- Testing
- Degarelix
- Where
- 3 sites in Canada
- Volunteers
- 50 people
- Sponsor
- British Columbia Cancer Agency
Benign Prostatic Hyperplasia
Trial of HoLEP vs. PVP in Treating BPH in Patients With Bleeding Tendency
Patients presented for BPH surgery at our out patient clinic will be assessed for abnormal bleeding profile. Patients with bleeding tendency will be offered either HoLEP or Greenlight laser PVP based on prostate size cut off…
- Trial name
- NCT02293759
- Testing
- HoLEP, Greenlight laser PVP
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Mansoura University