Clinical trials: Benign Hyperplasia of Prostate
Benign Prostatic Hyperplasia
Thulium Fiber Laser Enucleation of the Prostate (TFLEP) vs HoLEP With Moses Technology (m-HoLEP)
Enucleation of the prostate equips technology (usually laser) to effectively treat lower urinary tract symptoms associated with benign prostate hyperplasia (BPH).
- Trial name
- NCT04807296
- Testing
- TFLEP, m-HoLEP
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Prostatic Hyperplasia
Study to Evaluate the Symptomatic Relief Effects of FLOMAX® in Patients With Signs and Symptoms of Benign Prostatic Hyperplasia
Study to evaluate the symptomatic relief afforded by tamsulosin hydrochloride capsules in patients with signs and symptoms of benign prostatic hyperplasia (BPH).
- Trial name
- NCT02244242
- Testing
- Tamsulosin hydrochloride
- Volunteers
- 493 people
- Sponsor
- Boehringer Ingelheim
Benign Prostatic Hyperplasia
Efficacy and Safety of Combination Therapy Compared With Monotherapy in Patients With Benign Prostatic Hyperplasia
Efficacy and Safety of Combination Therapy Compared With Monotherapy in Patients With Benign Prostatic Hyperplasia
- Trial name
- NCT07870759
- Testing
- Finasteride 5 mg Tablet, single dose, Tamsulosin 0.4Mg Capsule
- Volunteers
- 660 people
- Sponsor
- Il-Yang Pharm. Co., Ltd.
Benign Prostatic Hyperplasia
Botulinum Toxin Injection for the Management of BPH
This is a double-blind randomized phase II trial to determine whether two different doses of BoNT/A injection into the prostate gland demonstrate sufficient improvement in the management of lower urinary symptoms due to BPH to…
- Trial name
- MIST2 (NCT00451191)
- Testing
- botulinum toxin type A (BoNT/A)
- Where
- 7 sites in United States
- Volunteers
- 134 people
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Benign Prostatic Hyperplasia
Treatment of Symptomatic BPH Patients Undergoing Anticoagulant Therapy Using the PlasmaButton Vaporization Electrode
The purpose of this observational study is to evaluate the outcomes of using the PlasmaButton electrode in the treatment on Benign Prostatic Hyperplasia (BPH) while on anticoagulation medication.
- Trial name
- NCT02019030
- Where
- 2 sites in United States
- Volunteers
- 5 people
- Sponsor
- Olympus Corporation of the Americas
Benign Prostatic Hyperplasia
Transperineal Intraprostatic Injection of PRX302 Under Ultrasound Guidance for Management of Prostatic Hyperplasia
The purpose of this study is to determine whether PRX302 is safe and effective in the treatment of moderate to severe Benign Prostatic Hyperplasia (BPH).
- Trial name
- TRIUMPH-1 (NCT00889707)
- Testing
- PRX302
- Where
- 9 sites in Canada
- Volunteers
- 92 people
- Sponsor
- Sophiris Bio Corp
Benign Prostatic Hyperplasia
MCS in Treating Lower Urinary Tract Symptoms (LUTS) Suggestive of Benign Prostatic Hyperplasia
Phase III, Randomized, double-blind, parallel placebo-controlled study. Two arms: MCS (30mg/day) vs. placebo. Subproject MCS-2: alpha-blocker naïve subjects Subproject MCS-3: subjects responding poorly to alpha-blocker
- Trial name
- NCT00501371
- Testing
- MCS
- Where
- 5 sites in Taiwan
- Volunteers
- 85 people
- Sponsor
- Health Ever Bio-Tech Co., Ltd.
Benign Prostate Hypertrophy(BPH)
Bipolar Enucleation of the Prostate Versus Bipolar TURP
Bipolar enucleation of the prostate (BEEP) was introduced to treat patients with large prostate. The study compared the functional outcomes and perioperative complications of bipolar TURP and bipolar enucleation of large…
- Trial name
- TURP (NCT07718256)
- Testing
- bTURP, BEEP
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Ain Shams University
Benign Prostatic Hyperplasia
Dose Ranging Study of Alfuzosin in Patients With Lower Urinary Tract Symptoms Related to Benign Prostatic Hyperplasia
The primary objective is to assess the dose-response relationship of SL77.0499 10 (alfuzosin hydrochloride) 5 mg, 10 mg, 15 mg, and placebo once daily during a 12-week oral administration period for the efficacy in patients with…
- Trial name
- NCT00409357
- Testing
- SL77.0499-10 (alfuzosin hydrochloride)
- Where
- Japan
- Volunteers
- 473 people
- Sponsor
- Sanofi
Benign Prostate Hyperplasia
Low Dose Bupivacaine Spinal for Trans Uretral Prostatectomy.
Spinal anesthesia, is used during the transuretheral resection of the prostate.Low dose hyperbaric local anesthetics have been used to enhance the resolution of the spinal block.
- Trial name
- TURP (NCT01861041)
- Testing
- Heavy Bupivacaine, Isobaric Bupivacaine
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people
- Sponsor
- Diskapi Yildirim Beyazit Education and Research Hospital
Benign Prostate Hyperplasia
Evaluation of Finastride Effect in Different Dosage on the Amount of Perioperative Bleeding in Transurthral Resection of Prostate
Preoperative use of finastride will decrease the amount of perioperative blood loss during and after TURP The effect of finastride on decreasing the amount of perioperative blood loss during and after TURP is dose dependent…
- Trial name
- TURP (NCT01627522)
- Testing
- TURP
- Where
- Iran
- Volunteers
- 60 people
- Sponsor
- Shiraz University of Medical Sciences
Erectile Dysfunction, Benign Prostatic Hyperplasia
Efficacy, Safety and Dose-response of Udenafil in Patients With Benign Prostatic Hyperplasia and Erectile Dysfunction
The purpose of this study is to evaluate the efficacy, dose-response and safety of udenafil 25 mg, 50 mg and 75 mg every day (q.d.) for 12 weeks in the treatment of lower urinary tract symptoms (LUTS) associated with benign…
- Trial name
- NCT01967251
- Testing
- Udenafil
- Where
- 8 sites in Mexico
- Sponsor
- Takeda
Benign Prostate Enlargement, Lower Urinary Tract Symptoms
The Impact of Chatbot-aid on Promoting Self-management of Men's Health in the Post COVID-19 Era
The AI chatbot as an artificial intelligence technology provides disease information and health care through digital assistance.
- Conditions
- Benign Prostate Enlargement, Lower Urinary Tract Symptoms, Erectile Dysfunction
- Trial name
- NCT05765331
- Testing
- Chatbot
- Where
- Taiwan
- Volunteers
- 100 people
- Sponsor
- Cheng-Hsin General Hospital
Prostatic Hyperplasia, Benign, Lower Urinary Tract Symptoms
Tadalafil Plus Tamsulosin for Male LUTS and ED
Metabolic Syndrome (MetS) is a complex epidemic disorder with an impact on both lower urinary tract symptoms (LUTS) and erectile dysfunction (ED).
- Conditions
- Prostatic Hyperplasia, Benign, Lower Urinary Tract Symptoms, Erectile Dysfunction, Metabolic Syndrome
- Trial name
- NCT04383093
- Testing
- Tadalafil 5mg
- Volunteers
- 75 people
- Sponsor
- University of Florence
Atherosclerotic Cardiovascular Disease (ASCVD), Benign Prostatic Hypertrophy (BPH)
Protective Effect of 5-Alpha Reductase Inhibitors on Atherosclerotic Cardiovascular Disease in Populations With BPH: Evidence From UK Biobank Cohort and Chinese Single Center Database Studies
To assess the impact of 5-alpha reductase inhibitors (5-ARIs) on the incidence of atherosclerotic cardiovascular disease (ASCVD) in patients with benign prostatic hyperplasia (BPH).
- Trial name
- NCT07196280
- Testing
- 5-Alpha Reductase Inhibitors
- Volunteers
- 10,000 people
- Sponsor
- Chinese PLA General Hospital
Nocturia
Efficacy Study of Fedovapagon for Nocturia in Men With Benign Prostatic Hyperplasia (BPH)
This study will investigate the efficacy and safety of fedovapagon in the treatment of nocturia in men with BPH.
- Trial name
- EQUINOC (NCT02637960)
- Testing
- Fedovapagon 2 mg
- Where
- 48 sites in United States
- Volunteers
- 432 people
- Sponsor
- Vantia Ltd
Benign Prostatic Hyperplasia
Study to Treat Patients Who Have Signs and Symptoms of Benign Prostatic Hyperplasia (BPH) With Tadalafil Daily
The purpose of this study is to determine whether an experimental drug known as tadalafil given once daily can reduce the symptoms associated with Benign Prostatic Hyperplasia (straining, urinary frequency, feeling like your…
- Trial name
- NCT00827242
- Testing
- tadalafil
- Where
- 27 sites in United States, Argentina and 3 more
- Volunteers
- 325 people
- Sponsor
- Eli Lilly and Company
Benign Prostatic Hyperplasia (BPH)
TURP Outcome Prediction Calculator Study
The goal of this observational study is to identify which preoperative clinical, ultrasound, and uroflowmetry parameters can help predict the success of transurethral resection of the prostate (TURP) in adult male patients with…
- Trial name
- TURP-SCORE (NCT07277556)
- Volunteers
- 200 people
- Sponsor
- General Hospital Sveti Duh
Nonmalignant Neoplasm, Prostate Cancer
MRI and Magnetic Resonance Spectroscopy Imaging in Patients Receiving Dutasteride for Benign Prostatic Hypertrophy and Low-Risk Prostate Cancer
RATIONALE: Diagnostic procedures, such as MRI and magnetic resonance spectroscopy imaging, may help in learning how well dutasteride works in patients with benign prostatic hypertrophy and low-risk prostate cancer.
- Trial name
- NCT00706966
- Testing
- dutasteride
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of California, San Francisco
Lower Urinary Tract Symptoms, Benign Prostatic Hyperplasia
Efficacy Study of HoLEP and TURP on LUTS Secondary to BPH
The purpose of this study is to compare of Efficacy and Safety Between Holmium Laser Enucleation of the Prostate (HoLEP) and Transurethral Resection of the Prostate (TURP) on the Lower Urinary Tract Symptoms (LUTS) Secondary to…
- Trial name
- NCT00877669
- Testing
- Transurethral resection of the prostate, Holmium Laser Enucleation of the Prostate
- Where
- South Korea
- Volunteers
- 313 people
- Sponsor
- Samsung Medical Center