Clinical trials: Benign Hyperplasia of Prostate
Benign Prostatic Hyperplasia
Optilume BPH Catheter System in Benign Prostatic Hyperplasia (BPH)
A post-marketing study using Optilume Catheter System for benign prostatic hyperplasia.
- Trial name
- SUMMIT (NCT05567666)
- Testing
- Optilume Catheter System
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- Dean Elterman
BPH, Lower Urinary Tract Symptoms
Transperineal Laser Ablation for Percutaneous Treatment of Benign Prostatic Hyperplasia
This study investigated the effectiveness and safety of SoracteLite ™- Trans-Perineal Laser ablation (TPLA) in the treatment of patients with symptomatic Benign Prostatic Hyperplasia (BPH) at 6 and 12 months follow-up
- Trial name
- NCT04198103
- Testing
- Transperineal Focal Laser Ablation (TPLA)
- Where
- 4 sites in Italy
- Volunteers
- 160 people
- Sponsor
- University of Rome Tor Vergata
BPH With Other Lower Urinary Tract Symptoms
Administration of Tadalafil in Patients With Benign Prostatic Hyperplasia
The aim of the present study is to evaluate the efficacy and safety of once daily administration PDE5 inhibitors, tadalafil for 3 months as anti-inflammatory, antiproliferative and relaxant effects in ED with BPH patients.
- Trial name
- NCT06466369
- Testing
- Tadalafil
- Where
- Egypt
- Volunteers
- 306 people
- Sponsor
- Al-Azhar University
Benign Prostatic Hyperplasia, Ejaculation
Factors Predicting The Success of Ejaculation Sparing Transurethral Resection of Prostate in Benign Prostatic Hyperplasia Patients
evaluate the factors predicting the success of ejaculation-sparing TURP in patients with BPH after surgery, in terms of voiding improvement and preserved ejaculation post-operatively.
- Trial name
- NCT07513896
- Testing
- ejaculatory preserving TURP
- Where
- Egypt
- Volunteers
- 108 people
- Sponsor
- Ain Shams University
Benign Prostatic Hyperplasia
Effect of Dutasteride on HIF-1alpha and VEGF in the Prostate
The purpose of this study is to determine whether dutasteride may influence the expression of angiogenesis factors such as hypoxia inducible factor (HIF)-1alpha and vascular endothelial growth factor (VEGF) in patients with lower…
- Trial name
- NCT00880672
- Testing
- dutasteride
- Volunteers
- 40 people
- Sponsor
- Seoul National University Hospital
Prostatic Hyperplasia With Urinary Obstruction
Green LEP vs ThuLEP in Management of Marked Enlarged Prostate
In this study the investigators aim to test TGreenlight (532-nm) laser Photoselective Enucleation of the Prostate (Green LEP) using (XPS) 180W system ) vs Thulium Laser 200 W Enucleation of the Prostate (ThuLEP) in reduction of…
- Trial name
- NCT03305861
- Testing
- ThuLEP, Green LEP
- Where
- Egypt
- Volunteers
- 110 people
- Sponsor
- Mansoura University
Benign Prostatic Hyperplasia, Post-Op Complication
Artery Embolization vs Operation of Benign Prostate Hyperplasia
Aim of the study is to compare prostate artery embolization (PAE) to the established surgical treatment for patient acceptance, morbidity, complications, and the functional outcomes.
- Conditions
- Benign Prostatic Hyperplasia, Post-Op Complication, Embolization Therapeutic, Transurethral Resection of Prostate Syndrome
- Trial name
- NORTAPE (NCT04084938)
- Testing
- Prostate operation or prostate artery embolization
- Where
- Norway
- Volunteers
- 140 people
- Sponsor
- Oslo University Hospital
Benign Prostate Hyperplasia
Efficacy and Safety of Tamsulosin/Solifenacin Combination Therapy in Patients With Voiding Symptoms and Moderate to Severe Storage Symptoms Due to Benign Prostate Hyperplasia
Efficacy and Safety of Tamsulosin/Solifenacin Combination therapy in Patients with voiding symptoms and moderate to severe storage symptoms due to Benign Prostate Hyperplasia : a randomized, double blinded, parallel design…
- Trial name
- NCT02827578
- Testing
- Tamsulosin, Solifenacin
- Where
- South Korea
- Volunteers
- 588 people
- Sponsor
- IlDong Pharmaceutical Co Ltd
Benign Prostatic Hyperplasia, Lower Urinary Track Symptoms
Ejaculation-Preserving Versus Conventional Dual Wavelength Diode Laser Vaporization of the Prostate
Surgery to relieve urinary blockage caused by an enlarged prostate works well, but most men lose antegrade ejaculation afterwards, because semen passes backwards into the bladder instead of forwards.
- Conditions
- Benign Prostatic Hyperplasia, Lower Urinary Track Symptoms, Bladder Outlet Obstruction
- Trial name
- EP-TUVP (NCT07777068)
- Testing
- Conventional dual-wavelength diode laser vaporization of the prostate, Ejaculation-preserving dual wavelength diode laser vaporization of the prostate
- Where
- Iraq
- Volunteers
- 119 people
- Sponsor
- ALI KAMAL M. SAMI
Lower Urinary Tract Symptoms, Benign Prostatic Hyperplasia
Open-Label Extension Study of MCS-2 in the Treatment of Lower Urinary Tract Symptoms
This is an open-label extension study of another study protocol, MCS-2-TWN-a. Subjects who have completed the 12-week treatment and procedures under the protocol MCS-2-TWN-a will be eligible for this study.
- Trial name
- MCS-2-TWN-c (NCT01002274)
- Testing
- MCS-2
- Where
- Taiwan
- Volunteers
- 180 people
- Sponsor
- Health Ever Bio-Tech Co., Ltd.
Urinary Retention
Early Removal of the Urethral Catheter Following Trans-urethral Resection of Prostate
Transurethral resection of prostate is the gold standard operation for bladder outflow obstruction due to benign prostatic enlargement. However, catheter removal day is variable.
- Trial name
- NCT04363970
- Testing
- removal of the urinary catheter
- Where
- Jordan
- Volunteers
- 200 people
- Sponsor
- University of Jordan
Benign Prostatic Hyperplasia, Micturition Disorder
The Effect of Urinating Through the Zipper or by Pulling Down the Trousers on Uroflowmetry Parameters in LUTS
There are many factors that affect uroflowmetry parameters. One of these is the urination position. Research has mostly focused on standing and sitting urination positions.
- Conditions
- Benign Prostatic Hyperplasia, Micturition Disorder, Urinary Obstruction, Urinary Tract Disease
- Trial name
- NCT06260917
- Testing
- position of urination
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Ankara City Hospital Bilkent
BPH, Nocturia
Use of Autologous Adipose-Derived Stem/Stromal Cells (AD-cSVF) in Symptomatic Benign Prostate Hypertrophy
Benign prostate hypertrophy (BPH) and inflammation are common non-cancerous enlargement of the prostate, which result in urinary interference and incomplete drainage of the bladder.
- Conditions
- BPH, Nocturia, BPH With Urinary Obstruction, Prostatism
- Trial name
- SVF-BPN (NCT02961114)
- Testing
- Microcannula Harvest Adipose, Centricyte 1000, IV Sterile Normal Saline
- Where
- 2 sites in United States
- Sponsor
- Robert W. Alexander, MD, FICS
Prostate Cancer
Comparing Water Vapour Thermal Therapy (Rezūm) and TURP
This is a randomized controlled trial using a non-inferiority design with the subjects randomized 1:1 to either water vapour thermal treatment (REZUM) arm or transurethral resection of prostate (TURP) arm.
- Trial name
- NCT05762198
- Testing
- Rezūm, TURP
- Where
- Hong Kong
- Volunteers
- 108 people
- Sponsor
- Chinese University of Hong Kong
Prostatic Hyperplasia
The Additive Value of Pyridostigmine to Silodosin in Acute Urinary Retention
Acute urine retention, AUR, is often considered the most serious consequence of aging men with progressive benign prostatic hyperplasia (BPH). AUR is defined as the sudden and painful inability to void freely.
- Trial name
- NCT06319469
- Testing
- silodosin 8 mg capsule and the pyridostigmine bromide 60 mg tablet, silodosin 8 mg capsule
- Where
- Egypt
- Volunteers
- 140 people
- Sponsor
- Beni-Suef University
Benign Prostatic Hyperplasia
A Long-Term Study Examining the Treatment of Benign Prostatic Hyperplasia With Photoselective Vaporization
To gain clinical experience with the GreenLight HPS System, a system designed to vaporize and coagulate tissue in the treatment of benign prostatic hyperplasia to reduce lower urinary tract symptoms.
- Trial name
- PVP (NCT00465101)
- Testing
- GreenLight HPS
- Where
- 9 sites in United States
- Volunteers
- 150 people
- Sponsor
- American Medical Systems
Urologic Diseases
Aquablation in Benign Prostatic Hyperplasia in Canada
To document the clinical outcome of Aquablation therapy for BPH patient in Canadian cohort.
- Trial name
- NCT05169892
- Testing
- Aquablation
- Where
- Canada
- Volunteers
- 25 people
- Sponsor
- Can-Am HIFU Inc.
Benign Prostatic Hyperplasia (BPH)
Post-Market Study to Assess iTind Safety in Comparison to UroLift
The study objective is to evaluate the efficacy and safety of the iTind device compared to UroLift.
- Trial name
- MT-08 (NCT04757116)
- Testing
- iTind, UroLift
- Where
- 19 sites in United States, United Kingdom
- Volunteers
- 256 people
- Sponsor
- Olympus Corporation of the Americas
Benign Prostatic Hyperplasia
Efficacy of Silodosin in the Treatment of Symptomatic Benign Prostatic Hyperplasia (BPH)
In this study the investigators had evaluated the effectiveness SILODOSIN (8 mg daily orally) in Benign prostatic Hyperplasia in comparison to Tamsulosin (0.4 mg daily orally) in a randomized controlled trial design.
- Trial name
- NCT04107896
- Testing
- Silodosin, Tamsulosin
- Where
- Bangladesh
- Volunteers
- 141 people
- Sponsor
- Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh
Lower Urinary Tract Symptoms (LUTS) Associated With Benign Prostatic Hyperplasia (BPH)
A Study to Evaluate the Tolerability and Efficacy of Tamsulosin 0.4mg OCAS Formulation in Patients Who Are Unsatisfied With the Treatment of Tamsulosin 0.2mg Conventional Formulation
This is an open-label, single-arm, prospective interventional study to assess the tolerability and efficacy of Harnalidge® OCAS® 0.4 mg in Taiwan patients who are unsatisfied with tamsulosin 0.2 mg for the treatment of lower…
- Trial name
- NCT02180789
- Testing
- Tamsulosin OCAS
- Where
- Taiwan
- Volunteers
- 100 people
- Sponsor
- Astellas Pharma Inc