Clinical trials: Benign Hyperplasia of Prostate
BPH, Urinary Incontinence
Effect of Group Preoperative Pelvic Floor Training for HoLEP
The main goal of this study is to see if group pelvic floor training before surgery can help prevent urinary incontinence after Holmium laser enucleation of the prostate (HoLEP) surgery.
- Trial name
- NCT05719220
- Testing
- Group preoperative pelvic floor training
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of California, San Francisco
Benign Prostatic Hyperplasia
TURP; Complications and Outpatient Care
This study aims to investigate the impact of transurethral prostate resection in regard to complications. These are direct surgical complications, such as bleeding, infection and readmissions, as well as the long term…
- Trial name
- NCT03959917
- Testing
- transurethral resection of the prostate
- Where
- Sweden
- Volunteers
- 50 people
- Sponsor
- Umeå University
Benign Prostate Hyperplasia
A Study to Investigate the Pharmacokinetic Drug Interactions Between Dutasteride and Tadalafil in Healthy Male Subjects
This is open-Label, A Randomized, Crossover study to evaluate the safety and pharmacokinetic interaction after oral concomitant administration of Dutasteride and Tadalafil in healthy male volunteers.
- Trial name
- NCT02839122
- Testing
- Tadalafil, Dutasteride
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Yuyu Pharma, Inc.
Moderate-to-severe Benign Prostatic Hyperplasia (BPH)
Bioequivalence Study of AJU-G721 and G721R in Healthy Adult Volunteers Under Fasting Conditions
To evaluate and compare the safety and pharmacokinetic profiles of "AJU-G721" (test drug) and "G721R" (reference drug) in healthy adult male subjects.
- Trial name
- NCT07643220
- Testing
- Test Drug, Reference Drug
- Where
- South Korea
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- AJU Pharm Co., Ltd.
Benign Prostatic Hyperplasia
Prostate Bipolar Enucleation and Resection Versus Open Prostatectomy
Benign prostatic hyperplasia (BPH) is a frequent disease in aging men accompanied by bladder outlet obstruction (BOO). Open prostatectomy (OP) is still considered the first-line treatment for more than 80 ml prostate size.
- Trial name
- NCT05416606
- Testing
- transurethral bipolar enucleation and resection of the prostate, open surgical transvesical prostatectomy
- Where
- Egypt
- Volunteers
- 64 people
- Sponsor
- Helwan University
Prostatic Hyperplasia
Study to Characterise the Effect of Tamsulosin on Lower Urinary Tract Symptoms (LUTS) and Detrusor Motor Activity in Patients Affected by Benign Prostatic Hyperplasia (BPH) and Storage Urinary Symptoms
Study to evaluate the efficacy of tamsulosin on storage symptoms and detrusor motor activity in patients with LUTS suggestive of BPH and relevant storage symptoms
- Trial name
- NCT02245490
- Testing
- Tamsulosin HCl controlled release capsules
- Volunteers
- 153 people
- Sponsor
- Boehringer Ingelheim
Benign Prostatic Hyperplasia
The Edison System for Treatment of Benign Prostatic Hyperplasia (BPH) Using Histotripsy
The purpose of this trial is to evaluate the safety of histotripsy using the HistoSonics Edison System for treatment of BPH.
- Trial name
- WOLVERINE (NCT07214675)
- Testing
- HistoSonics Edison System
- Where
- Hong Kong
- Volunteers
- 80 people
- Sponsor
- HistoSonics, Inc.
Benign Prostatic Hyperplasia, Lower Urinary Tract Symptoms
Focal Laser Ablation for Benign Prostatic Hyperplasia
Efficacy of Ultrasound Guided Percutaneous Transperineal Laser Ablation in Benign Prostatic Hypertrophy Patients: Non-Pharmacological Interventional Study
- Trial name
- NCT04044573
- Testing
- Transperineal Focal Laser Ablation (TPLA)
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- University of Rome Tor Vergata
Benign Prostatic Hyperplasia
Comparison of Finasteride and Tamsulosin for Treatment of Benign Prostatic Hyperplasia (BPH) (MK-0906A-149 AM2)
This study is designed to compare safety and efficacy of monotherapy finasteride to combination therapy (finasteride and tamsulosin) in Asian men with benign prostatic hyperplasia (BPH) who are at least 50 years of age or older.
- Trial name
- NCT01534351
- Testing
- Finasteride, Tamsulosin
- Volunteers
- 1 people
- Sponsor
- Merck Sharp & Dohme LLC
Persistent Overactive Bladder Symptoms Post Benign Prostatic Hyperplasia Surgery
Tibial Nerve Stimulation for Post-BPH Overactive Bladder
A single-center, randomized, parallel-controlled design. Approximately 90 cases of persistent overactive bladder symptoms post benign prostatic hyperplasia surgery are expected to be enrolled.
- Trial name
- NCT06558539
- Testing
- Transcutaneous Tibial Nerve Stimulation(TTNS), Combination Therapy, Standard Medication Therapy
- Volunteers
- 90 people
- Sponsor
- Qing Yuan
Benign Prostatic Hyperplasia, Prostate Cancer
Effects of Alpha Blockers on Prostate-specific Antigen (PSA) Change in Men With Lower Urinary Tract Symptoms (LUTS)
The correlation between the change of serum prostate-specific antigen (PSA) or PSA velocity (PSAV) and severity of lower urinary tract symptoms (LUTS) has been poorly understood.
- Trial name
- NCT01250483
- Testing
- PSA measurement, uroflowmetry, IPSS, transrectal ultrasonography
- Where
- South Korea
- Volunteers
- 174 people
- Sponsor
- Seoul National University Hospital
Erectile Dysfunction, Benign Prostatic Hyperplasia
Efficacy and Safety of Tanzânia Association in the Treatment of Erectile Dysfunction Associated With Benign Prostatic Hyperplasia
The purpose of this study is to evaluate the efficacy and safety of Tanzânia association in adults with erectile dysfunction associated with Benign Prostatic Hyperplasia.
- Trial name
- NCT04185441
- Testing
- Tanzânia association, Omnic Ocas
- Where
- Brazil
- Volunteers
- 295 people
- Sponsor
- EMS
Benign Prostatic Hyperplasia, Lower Urinary Tract Symptom
Safety and Efficacy Study for the Treatment of BPH (Enlarged Prostate)
To evaluate the safety and efficacy of the Rezūm System and assess its effect on urinary symptoms secondary to benign prostatic hyperplasia (BPH).
- Trial name
- REZUM (NCT01912339)
- Testing
- Rezum System, Rigid Cystoscopy
- Where
- 15 sites in United States
- Volunteers
- 197 people
- Sponsor
- Boston Scientific Corporation
BPH
Investigating Medication vs. Prostatic Urethral Lift: Assessment and Comparison of Therapies for BPH
This prospective, multicenter, two-arm, 1:1 randomized controlled trial (RCT) will enroll approximately 250 males at approximately 25 sites located within the United States.
- Trial name
- IMPACT (NCT04987892)
- Testing
- UroLift System, Tamsulosin Hydrochloride
- Where
- United States
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- NeoTract, Inc.
Transurethral Resection (TUR) Syndrome
The Effect of Su Jok Therapy on Postoperative Pain, Anxiety and Patient Satisfaction in Patients With BPH
This study is the first nursing study in the field of urology to examine the effect of Su Jok Therapy on postoperative pain, anxiety and patient satisfaction in patients who underwent Transurethral Resection of the Prostate with…
- Trial name
- SuJokTherapy (NCT06456632)
- Testing
- Intervention Su Jok Therapy
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Baskent University
Acute Urinary Retention
Alfuzosin for Treating Acute Urinary Retention
The primary objective of the study is to assess the efficacy of alfuzosin 10mg daily in the return to successful voiding after removal of the catheter following a first episode of acute urinary retention (AUR) in patients…
- Trial name
- NCT00336921
- Testing
- Alfuzosin
- Where
- China
- Volunteers
- 156 people
- Sponsor
- Sanofi
Benign Prostate Hyperplasia, Urinary Retention
Prostatic Artery Embolization Versus 532 nm Green Light PVP for Catheterized Patients
The primary objective is to assess whether prostatic artery embolization has a similar efficacy and safety profile as GreenLight PVP in treating patients with urinary retention secondary to benign prostate hyperplasia (BPH).
- Trial name
- NCT02006303
- Testing
- Green light PVP, Prostatic artery embolization
- Where
- 2 sites in Canada
- Volunteers
- 73 people
- Sponsor
- Royal Victoria Hospital, Canada
Benign Prostatic Hyperplasia (BPH) Requiring Surgical Resection
Conventional Fluid Management Versus Plethysmography Variability Index-based Goal-directed Fluid Management in Patients Undergoing Transurethral Resection of the Prostate
Transurethral resection of the prostate (TURP) is a widely performed surgical procedure for the management of benign prostatic hyperplasia.
- Trial name
- TURP (NCT07669337)
- Testing
- Conventional Fluid Management, Plethysmography Variability Index (PVI)-Guided Goal-Directed Fluid Management
- Where
- Egypt
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Cairo University
Benign Prostatic Hyperplasia (BPH), Urinary Retention
A Study to Determine the Safety and Efficacy of a New Non-invasive Heating Garment to Reduce Urinary Hesitancy
To determine the safety and efficacy of the ThermaRx heating device for the application of controlled low level heat to improve symptoms of LUT dysfunction (hesitancy, urgency).
- Conditions
- Benign Prostatic Hyperplasia (BPH), Urinary Retention, Urinary Hesitancy Intermittent
- Trial name
- NCT00700505
- Testing
- FlowPants(R) Garment
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- ThermaRx, Inc.
Prostatic Hyperplasia
The Impact of Alna® Ocas® on Nocturia in Patients With Lower Urinary Tract Symptoms Suggestive of Benign Prostatic Hyperplasia (LUTS/BPH)
Study to assess efficacy, tolerability and safety parameters of a three month ALNA®OCAS® -treatment with special respect to nocturia
- Trial name
- NCT02245542
- Testing
- ALNA®OCAS®
- Volunteers
- 5,775 people
- Sponsor
- Boehringer Ingelheim