Clinical trials: Benign Hyperplasia of Prostate
Benign Prostatic Hyperplasia
A Study of an Investigational Study Drug for Benign Prostatic Hyperplasia (0906-140)
The purpose of this trial is to determine the efficacy and safety of an investigational drug in patients with benign prostatic hyperplasia.
- Trial name
- NCT00127179
- Testing
- MK0906, finasteride / Duration of Treatment: 48 weeks
- Volunteers
- 600 people
- Sponsor
- Organon and Co
BPH With Urinary Obstruction
Early Versus Late Catheter Removal in Patients With Acute Urinary Retention Secondary to BPH Under Tamsulosin Treatment
The aim of this work is to compare between early (3days) and late(7days) removal of urinary catheter after acute urine retention in patients with Benign Prostatic Hyperplasia under Tamsulosin treatment.
- Trial name
- NCT03280420
- Testing
- Early catheter removal, Late catheter removal
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Salem Hassan Salem Mohamed
Benign Prostatic Hyperplasia
The Efficacy, Onset of Effect, and Safety of Alfuzosin Once Daily in the Treatment of Lower Urinary Tract Symptoms of Benign Prostatic Hyperplasia: A Randomized, Placebo-Controlled Trial Using an Acute International Prostate Score
Primary: Evaluate the safety and onset of symptom relief using an acute I-PSS form (7 day form). Determine onset of urinary peak flow improvement after 7 days Secondary: Determine improvement in Bother Score after 7 \& 28 days…
- Trial name
- ALF-ACUTE (NCT00540891)
- Testing
- ALFUZOSIN
- Where
- United States
- Volunteers
- 372 people
- Sponsor
- Sanofi
Prostate Cancer, Benign Prostatic Hyperplasia
BOTOX in Men With Prostate Cancer With Lower Urinary Tract Symptoms(LUTS)/Benign Prostatic Hyperplasia (BPH)
This is a pilot study examining biological endpoints in men with localized prostate cancer who are scheduled to have radical prostatectomies and men with Benign Prostatic Hyperplasia/Lower Urinary Tract Symptoms (BPH/LUTS)…
- Conditions
- Prostate Cancer, Benign Prostatic Hyperplasia, Enlarged Prostate With Lower Urinary Tract Symptoms (LUTS)
- Trial name
- NCT01520441
- Testing
- BOTOX
- Where
- United States
- Sponsor
- The University of Texas Health Science Center, Houston
Healthy People, Benign Prostatic Hyperplasia
The Application of Multimodal Artificial Intelligence Systems in Prostate Cancer Diagnosis and Prognosis Analysis
Prostate-specific antigen (PSA) testing has limited specificity for prostate cancer diagnosis, leading to a high rate of unnecessary biopsies.
- Conditions
- Healthy People, Benign Prostatic Hyperplasia, Prostate Cancer
- Trial name
- NCT06589154
- Testing
- Multi-modal artificial intelligence model (BEAM)
- Where
- 10 sites in China
- Volunteers
- 1,651 people, healthy volunteers welcome
- Sponsor
- Shanghai Changzheng Hospital
Urinary Bladder, Overactive, Prostatic Hyperplasia, Benign
Comparison of Concurrent Endoscopic Prostate Surgery With Botox-A Injection and Postoperative Medical Therapy in BPH Patients With Overactive Bladder Symptoms
Intravesical OnabotulinumtoxinA (BoNT-A) injection performed concurrently with endoscopic prostate surgery provides superior clinical improvement at the 12th postoperative week compared to standard medical therapy in patients…
- Conditions
- Urinary Bladder, Overactive, Prostatic Hyperplasia, Benign, Bladder Outlet Obstruction, Botulinium Toxin-A
- Trial name
- BOPROST (NCT07554989)
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Taksim Egitim ve Arastirma Hastanesi
Benign Prostatic Hyperplasia With Outflow Obstruction
Short Term Outcomes Of Bipolar Prostate Resection (BPR) Versus Diode Laser Ablation Versus Holmium Laser Enucleation Of Prostate Above 80 Grams With Minimum One Year Follow Up Duration.
Randomized Controlled Study Comparing Safety, Efficacy and Short Term Outcomes Of Bipolar Prostate Resection (BPR) Versus Diode Laser Ablation Versus Holmium Laser Enucleation Of Prostate Above 80 Grams With Minimum One Year…
- Trial name
- NCT07410390
- Testing
- bipolar resection of the prostate, holimum laser enucleation of the prostate, diode laser ablation of the prostate
- Volunteers
- 105 people
- Sponsor
- Ain Shams University
Benign Prostatic Hyperplasia
A Study to Determine the Improvement of the Symptoms of Benign Prostatic Hyperplasia (BPH) When Switching Subjects From Proscar to Avodart
Hypothesis: Dutasteride will perform better than finasteride in decreasing prostate volume, improving symptoms based on International Prostate Symptom score,and lower pvr based on the scientific information that dutasteride…
- Trial name
- NCT00690950
- Testing
- Dutasteride
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Urologic Consultants of Southeastern PA
Benign Prostatic Hyperplasia
A Study in Benign Prostatic Hyperplasia
The purpose of this trial is to evaluate the effect of tadalafil 5 milligrams (mg) daily for 8 weeks compared to placebo on prostatic blood perfusion in men with signs and symptoms of Benign Prostatic Hyperplasia (BPH), measured…
- Trial name
- NCT01152190
- Testing
- Tadalafil
- Where
- 5 sites in United States, Austria and 1 more
- Volunteers
- 97 people
- Sponsor
- Eli Lilly and Company
Benign Prostatic Hyperplasia
Prostatic Artery Embolization vs. Conventional Transurethral Prostatectomy in the Treatment of Benign Prostatic Hyperplasia
Benign prostatic hyperplasia (BPH) is a prevalent entity, affecting over 50% of men older than 60 years. The clinical picture of the disease includes lower urinary tract symptoms such as interrupted and weak urinary stream…
- Trial name
- NCT02054013
- Testing
- Prostatic artery embolization, monopolar transurethral prostatectomy
- Where
- Switzerland
- Volunteers
- 101 people
- Sponsor
- Daniel Stephan Engeler
BPH With Urinary Obstruction, Male
Holmium Laser vs Bipolar Enucleation of a Large Volume BPH: a Randomised Controlled Study
To compare bipolar plasmakinetic enucleation versus holmium laser enucleation for management of large BPH.
- Trial name
- BPH (NCT03998150)
- Testing
- Holmium laser enucleation of the prostate, Bipolar plasma kinetic enucleation of the prostate
- Where
- Egypt
- Volunteers
- 64 people
- Sponsor
- Cairo University
Benign Prostate Hypertrophy(BPH), LUTS(Lower Urinary Tract Symptoms)
Safety and Efficacy of MILEP Versus Standard EEP
Endoscopic enucleation of the prostate (EEP) is a standard treatment for benign prostatic hyperplasia (BPH), with modifications such as MiLEP that utilizes smaller instruments.
- Trial name
- MILES (NCT06839768)
- Testing
- Standard endoscopic enucleation of the prostate (EEP), MiLEP
- Where
- Russia
- Volunteers
- 340 people
- Sponsor
- Sechenov University
Benign Prostatic Hyperplasia
The Effect of Traditional Chinese Medicine on Benign Prostatic Hyperplasia
This randomized, double-blinded, placebo-controlled, crossover clinical trial aims to investigate the effect of VGH-BPH1, a scientific Chinese medicine powder prescription, on patients with benign prostatic hyperplasia.
- Trial name
- NCT03829904
- Testing
- VGH-BPH1
- Where
- Taiwan
- Volunteers
- 23 people
- Sponsor
- Taipei Veterans General Hospital, Taiwan
Benign Prostatic Hyperplasia
Questioning Patients About Adverse Medical Events
This trial studies whether 3 different methods of asking patients about adverse medical events in a clinical trial affects the rate of reported side effects.
- Trial name
- NCT00187616
- Where
- United States
- Volunteers
- 214 people
- Sponsor
- University of California, San Francisco
Benign Prostate Hypertrophy(BPH), Obstructive Sleep Apnea( OSA)
Nocturnal Hypoxemia and Benign Prostatic Hyperplasia in OSA Patients
Obstructive Sleep apnea (OSA) is a common sleep disorder characterized by frequent partial or complete obstructions of the upper airway during sleep leading to sleep fragmentation and sympathetic activation.
- Trial name
- NCT07058038
- Where
- Egypt
- Volunteers
- 91 people
- Sponsor
- Mansoura University
Benign Prostatic Hyperplasia (BPH)
To Linguistically and Psychometrically Validate the Hong Kong Chinese Version of the BPH 3-item Questionnaire
This study is to linguistically and psychometrically validate the translated and culturally adapted Hong Kong Chinese version of the BPH 3-item questionnaire.
- Trial name
- NCT05785286
- Testing
- BPH 3-item questionnaire
- Where
- 2 sites in Hong Kong
- Volunteers
- 66 people
- Sponsor
- Chinese University of Hong Kong
Intraoperative Floppy Iris Syndrome, Cataract
Pupillary Dilator Muscle Thickness as a Potential Predictor of Intraoperative Floppy Iris Syndrome
Intraoperative Floppy Iris Syndrome (IFIS) is a potencial complication encountered during cataract surgery in patients treated with α1-adrenergic receptor antagonists (α1-ARAs) for lower urinary tract symptoms.
- Conditions
- Intraoperative Floppy Iris Syndrome, Cataract, Age-related Cataract, Adrenergic Receptor Antagonist Adverse Reaction
- Trial name
- NCT07517094
- Where
- Czechia
- Volunteers
- 30 people
- Sponsor
- University Hospital Olomouc
Prostate Disease, Malignancy
Self-Administered Nitrous Oxide (SANO) During Transrectal Prostate Biopsy to Reduce Patient Anxiety and Pain
Transrectal prostate biopsy is a commonly performed ambulatory procedure for diagnosing prostate cancer. Prostate biopsy are associated with pain or anxiety.
- Conditions
- Prostate Disease, Malignancy, Benign Prostatic Hyperplasia, Prostate Cancer
- Trial name
- NCT05803096
- Testing
- Self-Administered Nitrous Oxide, Oxygen
- Where
- United States
- Volunteers
- 143 people, healthy volunteers welcome
- Sponsor
- Beth Israel Deaconess Medical Center
Benign Prostatic Hypertrophy
Safety and Efficacy of QD Versus BID Silodosin With Lower Urinary Tract Symptoms Suggestive of BPH
Korea has newly adopted 8mg Silodosin once daily. Against these backdrops, this clinical study is designed to demonstrate that the newly adopted dose is not inferior to the existing dose in its efficacy and safety.
- Trial name
- NCT01260129
- Testing
- Silodosin
- Where
- 14 sites in South Korea
- Volunteers
- 424 people
- Sponsor
- JW Pharmaceutical
Benign Prostatic Hyperplasia
Results of Selective Prostatic Arterial Embolization in Patients With Indwelling Urinary Catheter Due to Benign Prostatic Hyperplasia Refractory to Medical Treatment.
Background: Patients with indwelling urinary catheter for chronic retention due to obstructive BPH refractory to medical therapy are candidates for prostatectomy still considered as the gold standard of treatment.
- Trial name
- Prost-EMBOL (NCT01931605)
- Testing
- Prostatic arterial embolization using BeadBlock (Terumo)
- Where
- France
- Volunteers
- 2 people
- Sponsor
- University Hospital, Rouen