Clinical trials: Benign Pancreas Tumor
Breast Cancer
Women At Risk: The High Risk Breast Cancer Program
The purpose of this study is to increase understanding of women who are at high risk for developing breast cancer. Data from this group will be collected and entered into a registry.
- Trial name
- WAR (NCT01034891)
- Where
- 2 sites in United States
- Volunteers
- 2,000 people
- Sponsor
- New York Presbyterian Hospital
Pancreatic Cancer, Benign Pancreatic Disease
Interrogation of Exosome-mediated Intercellular Signaling in Patients With Pancreatic Cancer
The purpose of this study is to isolate and analyze exosomes, which are tiny carriers of important proteins and nucleic acids that serve as messenger systems in the blood and tissue.
- Trial name
- NCT02393703
- Where
- United States
- Volunteers
- 181 people, healthy volunteers welcome
- Sponsor
- Memorial Sloan Kettering Cancer Center
Benign Neoplasm of Body of Pancreas, Benign Neoplasm of Tail of Pancreas
Validation of 3 Dimensional Laparoscopic System in Disral Pancreatectomy and Splenectomy
Traditionally, laparoscopy has been based on 2-dimensional (2D) imaging, which has represented a considerable challenge for those approaching this technique.
- Trial name
- NCT02757690
- Testing
- 3-dimensional distal pancreatectomy, 2-dimensional distal pancreatectomy
- Volunteers
- 60 people
- Sponsor
- Asan Medical Center
Pancreas Cancer
DNA Microarray Study of Pancreas Cancer
Pancreas cancer and precancerous cysts can be difficult to diagnose. Sometimes biopsies do not show cancer when cancer is actually present.
- Trial name
- NCT00680420
- Testing
- fine needle aspiration biopsy
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- Oregon Health and Science University
Pancreatectomy, Distal Pancreatectomy (DP)
Laparoscopic Versus Robot-assisted Left-sided Pancreatectomy for Benign and Pre-malignant Lesions (DIPLOMA-3)
The DIPLOMA-3 trial is an international, multicenter, patient-blinded randomized controlled trial comparing laparoscopic and robot-assisted left-sided pancreatectomy.
- Conditions
- Pancreatectomy, Distal Pancreatectomy (DP), Pancreatic Neoplasms, Pancreatic Adenoma
- Trial name
- DIPLOMA-3 (NCT06939023)
- Testing
- Laparoscopic minimally invasive left-sided pancreatecomy, Robot-assisted minimally invasive left-sided pancreatecomy
- Where
- Netherlands
- Volunteers
- 256 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Biliary Tract Neoplasms, Pancreatic Carcinoma
A Prospective Study of UCAD for Diagnosing Benign or Malignant Biliary Obstruction and Follow-up
Chromosomal instability (CIN) refers to ongoing chromosome segregation errors throughout consecutive cell divisions. CIN is a hallmark of human cancer, and it is associated with poor prognosis, metastasis, and therapeutic…
- Conditions
- Biliary Tract Neoplasms, Pancreatic Carcinoma, Gallbladder Cancer, Pancreatic Head Carcinoma
- Trial name
- NCT05237193
- Testing
- The level of CIN
- Where
- China
- Volunteers
- 400 people
- Sponsor
- Xinhua Hospital, Shanghai Jiao Tong University School of Medicine
Cancer Risk, Cancer Predisposition Syndrome
InAdvance: Surveillance, Prevention, and Interception in a Population at Risk for Cancer
This research study is creating a way to collect and store specimens and information from participants who may be at an increased risk of developing cancer, or has been diagnosed with an early phase of a cancer or a family member…
- Conditions
- Cancer Risk, Cancer Predisposition Syndrome, Hereditary Cancer Prediction, Childhood Cancer Survivors
- Trial name
- NCT05463796
- Testing
- Samples
- Where
- United States
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- Dana-Farber Cancer Institute
Breast Cancer, Benign Breast Disease
Promoting Earlier Detection of Breast Cancer in Rwanda: Scaleup in the National Health Care System
This observational study evaluates scale-up of a breast cancer early detection program in Rwanda that was initially piloted in a single district.
- Trial name
- NCT04258085
- Testing
- Early diagnosis program combined with electronic medical record
- Where
- Rwanda
- Volunteers
- 17,379 people
- Sponsor
- Brigham and Women's Hospital
Benign Pancreatic Neoplasm, Malignant Pancreatic Neoplasm
"Answers in Hours" A Randomized Controlled Trial Using Microbiome Metagenomics for Bile Duct Cultures
This trial evaluates whether testing of bile with nanopore sequencing results in earlier detection of bacteriobilia (bacteria in bile) that may lead to surgical site infections in patients undergoing surgery for benign or…
- Trial name
- NCT05523154
- Testing
- Biospecimen Collection, Laboratory Procedure, Nanopore Sequencing
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Mayo Clinic
Pancreatic Neuroendocrine Tumors
Comparative Study of Robotic, Laparoscopic and Open Surgery for Enucleation of Benign Pancreatic Neoplasms
To determine the efficacy and safety of robotic, laparoscopic and open surgery for enucleation of benign pancreatic neuroendocrine tumors
- Trial name
- NCT02125929
- Testing
- Robotic surgery, Laparoscopic surgery, Open surgery
- Where
- China
- Volunteers
- 156 people
- Sponsor
- Peking Union Medical College Hospital
Breast Cancer, Benign Breast Disease
Evaluating Scaleup of an Adapted Breast Cancer Early Diagnosis Program in Rwanda
Breast cancer incidence is increasing in low- and middle-income countries (LMICs) and breast cancer mortality is high in these regions largely due to late stage diagnoses.
- Conditions
- Breast Cancer, Benign Breast Disease, Cervix Cancer
- Trial name
- NCT05364138
- Where
- Rwanda
- Volunteers
- 2,357 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Mucinous Cystic Tumor With Moderate Dysplasia, Mucinous Cystadenoma of Pancreas
Endoscopic Ultrasound (EUS) Guided Ethanol With Paclitaxel Ablation for Pancreatic Mucinous Cystic Neoplasm
Pancreatic cysts are becoming diagnosed more frequently due to the increased use and sensitivity of imaging. A subset of these cysts are pre-cancerous, therefore suggested treatment is surgery for removal.
- Conditions
- Mucinous Cystic Tumor With Moderate Dysplasia, Mucinous Cystadenoma of Pancreas, Mucinous Cystadenocarcinoma of Pancreas, Benign Neoplasm of Pancreas
- Trial name
- NCT01525706
- Testing
- Ethanol and Paclitaxel Injection
- Where
- Canada
- Volunteers
- 1 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Pancreas Cancer, Pancreas Neoplasm, Benign
Endoscopic Ultrasound Guided Tissue Sampling (The SharkBITE Study)
This study compares the diagnostic performance of Endoscopic ultrasound (EUS) guided fine needle aspiration and EUS guided core biopsy (SharkCore) in patients with a solid pancreatic mass.
- Conditions
- Pancreas Cancer, Pancreas Neoplasm, Benign, Chronic Pancreatitis, Pancreas Adenocarcinoma
- Trial name
- SharkBITE (NCT03532347)
- Testing
- EUS-FNA needle (Beacon)
- Where
- United Kingdom
- Volunteers
- 108 people
- Sponsor
- Newcastle-upon-Tyne Hospitals NHS Trust
Neoplasm, Pancreatic Cancer
Use of PET Imaging to Distinguish Malignant From Benign IPMN
Intraductal papillary mucinous neoplasm (IPMN) is a cystic pancreatic lesion that is a precursor to invasive pancreatic cancer. Differentiating whether an IPMN lesion is benign or malignant is critical, as the prognosis and…
- Trial name
- NCT01104116
- Testing
- [18F]-FDG PET/CT imaging
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Columbia University
Benign Neoplasm of Liver and/or Biliary Ducts, Neoplasm of Uncertain Behavior of Biliary System
Endoscopic Evaluation of Premalignant Lesions in the Biliary Tract and Pancreatic Ducts
Single operater pancreatico-cholangioscopy is performed through the working channel of conventional duodenoscopes. A visual evaluation of the biliary and pancreatic ductal systems is completed and obvious or suspicious…
- Conditions
- Benign Neoplasm of Liver and/or Biliary Ducts, Neoplasm of Uncertain Behavior of Biliary System, Benign Neoplasms of the Pancreas, Neoplasms of the Pancreas
- Trial name
- NCT02057146
- Testing
- Duodenoscopy, pancreatoscopy, cholangioscopy, confocal microscopy
- Where
- Sweden
- Volunteers
- 50 people
- Sponsor
- Karolinska University Hospital
Lower Gastrointestinal Neoplasms Benign, Pancreas Cancer
The Effects of Perioperative Painting Art Therapy (LOM® Solution Centered Art Therapy) in Surgical Patients
The investigators want to study whether the use of painting art therapy has an influence on the quality of life, the complication rate and the general outcome of major abdominal surgery.
- Conditions
- Lower Gastrointestinal Neoplasms Benign, Pancreas Cancer, Posttraumatic Stress Disorder, Depression, Anxiety
- Trial name
- NCT04524260
- Testing
- perioperative painting art therapy (LOM® solution centered art therapy), perioperative painting art therapy (LOM® solution centered art therapy) - control
- Where
- Switzerland
- Volunteers
- 80 people
- Sponsor
- University of Zurich
Breast Cancer, Benign Breast Disease
An Investigation Into Dielectric Assessment of Permittivity and Conductivity in Human Using a Novel Electrical Capacitance Tomography Scanner
The goal of this observational study is to investigate the ability of a the Z-scanner to identify and differentiate cancer and benign lesions from healthy breast tissue based on permittivity.
- Trial name
- DiCECT (NCT06264934)
- Testing
- Breast scan using the Z-scanner
- Where
- United Kingdom
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Zedsen Limited
Pancreas Neoplasm, Pancreas Cancer
Incidence of POPF in the Resection of the Left Pancreas With RFAT
This study evaluates the impact of the Radiofrequency assisted transection on the rate of postoperative pancreatic fistula (POPF) after performing distal pancreatectomies, central pancreatectomies and pancreatic enucleation
- Conditions
- Pancreas Neoplasm, Pancreas Cancer, Pancreatic Adenocarcinoma, Benign Pancreas Tumor
- Trial name
- RFATPancreas (NCT03570502)
- Where
- Spain
- Volunteers
- 38 people
- Sponsor
- Hospital del Mar
Neuroendocrine Tumors, Cystic Neoplasms
Endoscopic Ultrasound Guided Radiofrequency Ablation (EUS-RFA) for Small Benign Pancreatic Tumors
Incidental pancreatic solid or cystic lesions are diagnosed with increased frequency due to the widespread use of abdominal cross-sectional imaging to investigate unrelated symptoms.
- Trial name
- NCT02882503
- Testing
- endoscopic ultrasound - radiofrequency ablation (EUS-RFA)
- Where
- Taiwan
- Sponsor
- National Taiwan University Hospital
Pancreatic Tumor, Benign, Pancreatic Neuroendocrine Tumor
Minimally Invasive Pancreatic Enucleation With Main Pancreatic Duct Exposure, Repair or Reconstruction
The aim of this study is to evaluate the impact of concomitant main pancreatic duct exposure, repair, or reconstruction during minimally invasive pancreatic tumor enucleation on long-term patient prognosis and quality of life.
- Conditions
- Pancreatic Tumor, Benign, Pancreatic Neuroendocrine Tumor, Solid Pseudopapillary Tumor of the Pancreas
- Trial name
- NCT06024343
- Testing
- MPD Exposure, Repair or Reconstruction
- Where
- China
- Volunteers
- 230 people
- Sponsor
- Fudan University