Clinical trials: Benign Prostate Obstruction
Bladder Outlet Obstruction, Lower Urinary Tract Symptoms
The Value of Multiple Urine Flow Rate Measurements in Male Benign Prostatic Hyperplasia (BPH) Subjects
Crossover comparison of different flow meters with a digital home flow meter as a reference. Main hypothesis: Reapeated home flow measurements with a disposable device will provide a better understanding of the patients urinary…
- Trial name
- NCT00710749
- Testing
- Disposable device, Digital device, Clinic flow measurement
- Where
- 4 sites in United States, Netherlands and 2 more
- Volunteers
- 60 people
- Sponsor
- Wellspect HealthCare
Benign Prostatic Hyperplasia, Bladder Outlet Obstruction
Urinary CTGF in Benign Prostatic Obstruction
Benign prostatic obstruction (BPO) is one of the most common causes of bladder outlet obstruction (BOO) and may lead to progressive structural and functional alterations in the bladder over time.
- Conditions
- Benign Prostatic Hyperplasia, Bladder Outlet Obstruction, Lower Urinary Tract Symptom
- Trial name
- NCT07416981
- Volunteers
- 50 people
- Sponsor
- Tarik Emre Sener
Lower Urinary Tract Symptoms, Benign Prostatic Hyperplasia
PRescription Exercise for Older Men With Urinary Disease
This is a single-center pilot randomized controlled trial among 68 physically "inactive" older men with lower urinary tract symptoms (LUTS) attributed to benign prostatic hyperplasia (LUTS/BPH) assessing a 12-week remote exercise…
- Trial name
- PROUD (NCT06225479)
- Testing
- Exercise, Calls and Newsletter
- Where
- 2 sites in United States
- Volunteers
- 68 people
- Sponsor
- University of California, San Francisco
Benign Prostate Obstruction (BPO)
Enucleation Ratio as a Novel Predictor of Symptomatic Improvement After HoLEP
The goal of this observational study is to determine whether the rate of prostate tissue removed during surgery relative to the preoperative total prostate volume (referred to as the "enucleation ratio") predicts symptomatic…
- Trial name
- NCT07591688
- Testing
- Holmium laser enucleation of prostate (HoLEP)
- Where
- Turkey (Türkiye)
- Volunteers
- 400 people
- Sponsor
- Ondokuz Mayıs University
BPH With Urinary Obstruction With Other Lower Urinary Tract Symptoms
WATER III: Aquablation vs. Transurethral Laser Enucleation of Large Prostates (80 - 180mL) in Benign Prostatic Hyperplasia
Comparative analysis of efficacy and safety of Aquablation (AQUABEAM Robotic System®, PROCEPT BioRobotics, Redwood City, CA, USA) and transurethral laser enucleation as surgical therapy for benign prostatic hyperplasia with large…
- Trial name
- WATER III (NCT04801381)
- Testing
- Aquablation therapy, Transurethral laser enucleation
- Where
- 5 sites in Germany, United Kingdom
- Volunteers
- 202 people
- Sponsor
- University of Bonn
Benign Prostate Obstruction (BPO)
SteamOne - Prospective Database for Rezum Water Vapor Therapy of the Prostate
This study is to assess the clinical data of Rezum (water vapor therapy) in patients with BPO (benign prostate obstruction) and male LUTS (lower urinary tract symptoms) in terms of efficacy, durability and safety in a large…
- Trial name
- SteamOne (NCT05495633)
- Testing
- Collection and evaluation of clinical (CROMs) and patient-reported outcomes (PROMs), Analysis of uroflowmetry data by EmanoFlow Mobile Application (App) and Emano Clinic Portal
- Where
- 19 sites in Austria, Germany and 1 more
- Volunteers
- 1,000 people
- Sponsor
- University Hospital, Basel, Switzerland
Benign Prostatic Hyperplasia, Lower Urinary Tract Symptoms
Greenlight Vaporization vs Xpeeda Vaporesection
Bothersome lower urinary tract symptoms (LUTS) secondary to benign prostatic hyperplasia (BPH) is a common problem, which impact patients' quality of life.
- Trial name
- NCT04386941
- Testing
- Xpeeda Fibre Laser Vaporesection of the Prostate, Greenlight XPS Vaporization of the Prostate
- Where
- Canada
- Volunteers
- 97 people
- Sponsor
- Thunder Bay Regional Health Research Institute
Benign Prostatic Hyperplasia, Lower Urinary Tract Symptoms (LUTS) in Men With Benign Prostatic Hyperplasia (BPH)
Selective Median Lobe Surgery Outcomes Study
This prospective multicenter observational cohort study will evaluate clinical outcomes after selective median lobe transurethral surgery for benign prostatic obstruction.
- Conditions
- Benign Prostatic Hyperplasia, Lower Urinary Tract Symptoms (LUTS) in Men With Benign Prostatic Hyperplasia (BPH), Benign Prostatic Obstruction, Urinary Retention
- Trial name
- UNVEIL-BPO (NCT07699718)
- Testing
- Selective Median Lobe TURP, Selective Median Lobe HoLEP/AEEP
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 420 people
- Sponsor
- Necmettin Erbakan University
Lower Urinary Tract Symptoms, Voiding Dysfunction
Urodynamics for Prostate Surgery Trial; Randomised Evaluation of Assessment Methods
Background and study aims: The prostate gland sits around the exit of the bladder in men. As men get older, the prostate grows, and this can narrow the exit from the bladder, so that there is restriction of flow.
- Conditions
- Lower Urinary Tract Symptoms, Voiding Dysfunction, Benign Prostate Obstruction, Detrusor Underactivity
- Trial name
- UPSTREAM (NCT02193451)
- Testing
- Urodynamics, Usual care
- Where
- United Kingdom
- Volunteers
- 820 people
- Sponsor
- North Bristol NHS Trust
BPH With Urinary Obstruction
PUL vs TURP in BPH Patients With Urinary Retention
The study will be a prospective, randomized controlled trial comparing prostatic urethral lift (PUL) versus transurethral resection of prostate (TURP) in benign prostate hyperplasia (BPH) patients with urinary retention.
- Trial name
- PULTUR (NCT06037356)
- Testing
- Prostatic Urethral Lift, TURP
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Queen Mary Hospital, Hong Kong
Overactive Bladder
This is a Prospective, Randomized, Double-Blind Study Comparing Intravesical Injection of Botox® to Placebo.
The current study will investigate the comparative efficacy, safety and patient satisfaction of intradetrusor injections BOTOX® injections (200U) versus placebo (saline) injections in the treatment of OAB secondary to benign…
- Trial name
- BTX0621 (NCT00479596)
- Testing
- Botox
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Urological Sciences Research Foundation
Prostate Obstruction, Prostatic Hyperplasia
Bipolar Needlescopic Enucleation Versus Vapoenucleation of BPH
Transurethral resection of the prostate (TURP) is the current standard procedure for men with prostate volume 30-80 gm. In case with large prostate adenoma (>80 g), the resection time required by TURP is associated with increased…
- Conditions
- Prostate Obstruction, Prostatic Hyperplasia, Prostatic Hypertrophy, Benign
- Trial name
- NCT04331301
- Testing
- Bipolar Vapo-Enucleation of the prostate, Bipolar Needlescopic Enucleation of the prostate
- Where
- Egypt
- Volunteers
- 214 people
- Sponsor
- Benha University
Ejaculation Abnormal, BPH With Urinary Obstruction
Ejaculation Preserving Photoselective Vaporization Versus Plasma Kinetic Vaporization Versus Transurethral Resection Of The Prostate: A RCT
To Evaluate and compare the outcome and coast of ejaculation sparing management of BPH using 3 different techniques: PVP, PKVP and TURP. Ejaculation sparing TURP group is considered the standard control group.
- Conditions
- Ejaculation Abnormal, BPH With Urinary Obstruction, Prostatic Hyperplasia, Prostate Disease
- Trial name
- EPPROSTATECT (NCT03589196)
- Testing
- Ejaculation Preserving Photoselective Vaporization, Ejaculation Preserving Plasma Kinetic Vaporization, Ejaculation Preserving Transurethral Resection Of The Prostate
- Where
- Egypt
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Mansoura University
BPH, Intravesical Botox
Prostate Enucleation With Intravesical Botox Injections in Treating BPH and Bladder Overactivity
The aim of this study is to evaluate the effect of intravesical Botox injections on lower urinary tract symptoms (LUTS) when administered during Bipolar prostate enucleation surgery in patients with bladder outlet obstruction…
- Conditions
- BPH, Intravesical Botox, Bipolar Enucleation of the Prostate, Overactive Bladder
- Trial name
- BPH Botox (NCT05910983)
- Testing
- Bipolar enucleation of the prostate (BipolEP), Intravesical Botox injection
- Volunteers
- 100 people
- Sponsor
- Menoufia University
Benign Prostatic Hyperplasia With Outflow Obstruction
Short Term Outcomes Of Bipolar Prostate Resection (BPR) Versus Diode Laser Ablation Versus Holmium Laser Enucleation Of Prostate Above 80 Grams With Minimum One Year Follow Up Duration.
Randomized Controlled Study Comparing Safety, Efficacy and Short Term Outcomes Of Bipolar Prostate Resection (BPR) Versus Diode Laser Ablation Versus Holmium Laser Enucleation Of Prostate Above 80 Grams With Minimum One Year…
- Trial name
- NCT07410390
- Testing
- bipolar resection of the prostate, holimum laser enucleation of the prostate, diode laser ablation of the prostate
- Volunteers
- 105 people
- Sponsor
- Ain Shams University
Prostatic Hyperplasia With Urinary Obstruction
Green LEP vs ThuLEP in Management of Marked Enlarged Prostate
In this study the investigators aim to test TGreenlight (532-nm) laser Photoselective Enucleation of the Prostate (Green LEP) using (XPS) 180W system ) vs Thulium Laser 200 W Enucleation of the Prostate (ThuLEP) in reduction of…
- Trial name
- NCT03305861
- Testing
- ThuLEP, Green LEP
- Where
- Egypt
- Volunteers
- 110 people
- Sponsor
- Mansoura University
Benign Prostate Hyperplasia
Addition of Lidocaine to Levobupivacaine Reduces Intrathecal Block Duration
The main objective was to test the hypothesis that adding lidocaine to hyperbaric levobupivacaine could change the duration of levobupivacaine spinal block.
- Trial name
- NCT01675895
- Testing
- Levobupivacaine lidocaine spinal anesthesia, levobupivacaine Spinal anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Diskapi Teaching and Research Hospital
Benign Prostatic Hyperplasia, Lower Urinary Tract Symptoms
Ultrasound IPP to Predict Response to Medical Therapy in LUTS/BPH
This prospective cohort study evaluated whether transabdominal ultrasound measurement of intravesical prostatic protrusion predicts symptom severity and response to medical therapy in men aged 50 years or older with lower urinary…
- Conditions
- Benign Prostatic Hyperplasia, Lower Urinary Tract Symptoms, Bladder Outlet Obstruction
- Trial name
- NCT07306767
- Testing
- Transabdominal ultrasound measurement of intravesical prostatic protrusion, Alpha-adrenergic blocker, 5-alpha reductase inhibitor
- Where
- Egypt
- Volunteers
- 130 people
- Sponsor
- Ain Shams University
Acute Urinary Retention, Benign Prostate Obstruction
Early Versus Delayed Trial Without Catheter in Men With Acute Urinary Retention.
Acute urinary retention (AUR) is a sudden and painful condition. It occurs when a person is unable to urinate. In men, AUR is most often caused by an enlarged prostate, known as benign prostatic hyperplasia (BPH), which blocks…
- Conditions
- Acute Urinary Retention, Benign Prostate Obstruction, Benign Prostate Hyperplasia, Benign Prostate Hypertrophy(BPH)
- Trial name
- RELIEF (NCT07283484)
- Testing
- TWOC after 3 days, TWOC after 14 days
- Where
- 11 sites in Netherlands
- Volunteers
- 478 people
- Sponsor
- Liselot Ribbert
Benign Prostatic Hyperplasia, Lower Urinary Tract Symptoms
Ejaculation-Preserving Versus Standard Bipolar TUEP for BPH
This prospective randomized controlled trial will compare ejaculation-preserving bipolar transurethral enucleation of the prostate with standard bipolar transurethral enucleation of the prostate in sexually active men with benign…
- Conditions
- Benign Prostatic Hyperplasia, Lower Urinary Tract Symptoms, Benign Prostatic Obstruction
- Trial name
- EP-BTUEP (NCT07629479)
- Testing
- Ejaculation-Preserving Bipolar Transurethral Enucleation of the Prostate, Standard Bipolar Transurethral Enucleation of the Prostate
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Beni-Suef University