Clinical trials: Benign Prostatic Hypertrophy
Benign Prostate Hypertrophy(BPH)
Evaluation of the Application Effect of a Surgical Navigation System in HoLEP Surgery
3D imaging-assisted surgical navigation system was established using the following specific procedures: 1) Prostate MRI Acquisition and 3D Reconstruction: patient prostate MRI images are acquired, and professional engineers…
- Trial name
- NCT07251621
- Testing
- use the 3D imaging-assisted surgical navigation system during surgery
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Chinese PLA General Hospital
Benign Prostate Hypertrophy(BPH), Prostate Cancer (Diagnosis)
Application of Quantum Detection-Driven Artificial Intelligence Algorithms for Single-Molecule cfDNA Characterization in the Early Diagnosis of Prostate Cancer
This research project aims to develop a novel blood testing method integrating cutting-edge quantum sensing and artificial intelligence technologies to achieve precise, non-invasive early diagnosis of prostate cancer.
- Conditions
- Benign Prostate Hypertrophy(BPH), Prostate Cancer (Diagnosis), Prostate Neoplasm
- Trial name
- NCT07238959
- Testing
- Quantum Detection
- Where
- 7 sites in China
- Volunteers
- 1,100 people, healthy volunteers welcome
- Sponsor
- Shanghai Changzheng Hospital
Benign Prostatic Hyperplasia, Prostate Hyperplasia
5-Alpha Reductase 2 as a Marker of Resistance to 5ARI Therapy
The study is being conducted to learn why some patients with Benign Prostatic Hyperplasia (BPH) do not respond to a commonly used treatment drug, Finasteride.
- Conditions
- Benign Prostatic Hyperplasia, Prostate Hyperplasia, Prostate Disease, Prostate Hypertrophy
- Trial name
- NCT04288427
- Testing
- Finasteride
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Beth Israel Deaconess Medical Center
Atherosclerotic Cardiovascular Disease (ASCVD), Benign Prostatic Hypertrophy (BPH)
Protective Effect of 5-Alpha Reductase Inhibitors on Atherosclerotic Cardiovascular Disease in Populations With BPH: Evidence From UK Biobank Cohort and Chinese Single Center Database Studies
To assess the impact of 5-alpha reductase inhibitors (5-ARIs) on the incidence of atherosclerotic cardiovascular disease (ASCVD) in patients with benign prostatic hyperplasia (BPH).
- Trial name
- NCT07196280
- Testing
- 5-Alpha Reductase Inhibitors
- Volunteers
- 10,000 people
- Sponsor
- Chinese PLA General Hospital
Benign Prostate Hypertrophy(BPH)
Transurethral Focal Laser Ablation Versus Transurethral Prostatectomy For Management Of Benign Prostatic Obstruction
Introduction and objectives: Laser prostatectomy has become an increasingly popular and effective alternative to transurethral resection of the prostate (TURP) for the treatment of benign prostatic hyperplasia (BPH).-.
- Trial name
- NCT07196475
- Testing
- FOCAL LASER ABLATION OF PROSTATE
- Where
- Egypt
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Benign Prostatic Hypertrophy, Holmium Laser Enucleation of the Prostate
Outpatient Holmium LASER Enucleation of the Prostate: Benefit of MOSES(TM) 2.0 Technology
The aim of this study is to compare the success rate of outpatient surgery after holmium LASER enucleation of the prostate (HoLEP) for the treatment of BPH with and without the use of the MOSES 2.0 effect.
- Trial name
- MOSES (NCT05768776)
- Testing
- HoLEP patients without MOSES(TM) 2.0 effect (open label), HoLEP patients with MOSES(TM) 2.0 effect (open label)
- Where
- France
- Volunteers
- 200 people
- Sponsor
- University Hospital, Bordeaux
Benign Prostate Hypertrophy(BPH)
Investigating the Adjunctive Use of Mirabegron in the Early Post-Rezum Procedure Period
The investigators propose conducting a randomized controlled trial at the Men's Health Clinic to evaluate whether patients who start and continue mirabegron postoperatively after undergoing Rezum therapy experience enhanced…
- Trial name
- NCT07017439
- Testing
- Beta-3 agonists (Mirabegron/Myrbetriq)
- Where
- Canada
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Benign Prostate Hypertrophy(BPH)
Trial to Assess the Efficacy and Safety During Convective Radiofrequency Water Vapor Thermal Therapy (REZUM) for Benign Prostate Hyperplasia
The primary aim of the study is to show that methoxyflurane-lorazepam-percocet combination administrated 'per os' is non inferior to deep intravenous sedation in achieving analgesia during Rezum convective radiofrequency water…
- Trial name
- NCT07017452
- Testing
- Methoxyflurane - Penthrox, Control, Percocet Pill
- Where
- Canada
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Benign Prostate Hypertrophy(BPH), LUTS(Lower Urinary Tract Symptoms)
Safety and Efficacy of MILEP Versus Standard EEP
Endoscopic enucleation of the prostate (EEP) is a standard treatment for benign prostatic hyperplasia (BPH), with modifications such as MiLEP that utilizes smaller instruments.
- Trial name
- MILES (NCT06839768)
- Testing
- Standard endoscopic enucleation of the prostate (EEP), MiLEP
- Where
- Russia
- Volunteers
- 340 people
- Sponsor
- Sechenov University
Benign Prostate Hypertrophy(BPH), Prostate Cancer (Adenocarcinoma)
Investigation of the Diagnostic Role of miRNAs in PCa and BPH
Prostate cancer(PCa) is the second most common cause of cancer-related death in men after lung cancer. Diagnostic methods such as measurement of serum Prostate-specific antigen (PSA) levels used in the clinic still cannot…
- Trial name
- NCT06726070
- Where
- Turkey (Türkiye)
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Alanya Alaaddin Keykubat University
Benign Prostatic Hypertrophy
Wolf 24 F vs. Storz 28 F Laser Sheath Size for HoLEP
The purpose of this study is to compare two different types of scopes that can be used for HoLEP. HoLEP is performed through the urethra using a Laser scope to remove obstructing prostate tissue.
- Trial name
- NCT05308017
- Testing
- Richard Wolf 24F Laser scope, Karl Storz 28F Laser Scope
- Where
- United States
- Volunteers
- 152 people
- Sponsor
- Northwestern University
Prostate Hyperplasia, Benign Prostatic Hyperplasia
Transperineal Laser Ablation vs Transurethral Resection for Benign Prostatic Obstruction: A Randomized Clinical Trial
The primary objective of the study is to compare Trans-Perineal Laser Ablation of Prostate versus Trans-Urethral Resection of Prostate in the immediate impact on post-operative pain; in terms of relief in benign prostatic…
- Conditions
- Prostate Hyperplasia, Benign Prostatic Hyperplasia, Benign Prostatic Hypertrophy, Benign Prostatic Hypertrophy With Outflow Obstruction
- Trial name
- NCT04781049
- Testing
- Trans-Perineal Laser Ablation of Prostate, Trans-Urethral Resection of Prostate
- Where
- Italy
- Volunteers
- 51 people
- Sponsor
- San Carlo di Nancy Hospital
Benign Prostatic Hypertrophy
Transurethral Vapor Enucleation Resection of the Prostate (TVERP), Bipolar TURis and HoLEP
To verify the safety and efficacy of the use of the plasma vaporisation button in Transurethral Vapor Enucleation and Resection of the prostate (TVERP) for treatment of Benign prostatic hypertrophy (BPH) patients with prostate…
- Trial name
- NCT04398420
- Testing
- TVERP, TURis, HoLEP
- Where
- 3 sites in China
- Volunteers
- 29 people
- Sponsor
- Olympus Surgical Technologies Europe
Prostate Obstruction, Prostatic Hyperplasia
Bipolar Needlescopic Enucleation Versus Vapoenucleation of BPH
Transurethral resection of the prostate (TURP) is the current standard procedure for men with prostate volume 30-80 gm. In case with large prostate adenoma (>80 g), the resection time required by TURP is associated with increased…
- Conditions
- Prostate Obstruction, Prostatic Hyperplasia, Prostatic Hypertrophy, Benign
- Trial name
- NCT04331301
- Testing
- Bipolar Vapo-Enucleation of the prostate, Bipolar Needlescopic Enucleation of the prostate
- Where
- Egypt
- Volunteers
- 214 people
- Sponsor
- Benha University
Benign Prostatic Hypertrophy
The Safety and Efficacy of Ozarelix to Treat Men With Lower Urinary Tract Symptoms Due to Enlargement of the Prostate
This study is to compare the efficacy and safety of ozarelix 15 mg given intramuscular (IM) 2 weeks apart on the improvement of symptoms and the duration of improvement for up to 6 months in men with Benign Prostatic Hypertrophy…
- Trial name
- NCT00427219
- Testing
- Ozarelix
- Where
- 13 sites in United States
- Volunteers
- 74 people
- Sponsor
- Spectrum Pharmaceuticals, Inc
Benign Prostatic Hypertrophy
Feasibility Study of Photovaporisation of Prostate With a Limitated Length of Catheterization of 3 Hours
Benign hypertrophy of the prostate (BPH) is the most frequent pathology in the urinary tract of middle-aged men. In recent years, to enable BPH treatment with larger volumes and to reduce the risk of hemorrhage known to be…
- Trial name
- PRECOCE (NCT02401581)
- Testing
- Catheter
- Where
- 12 sites in France
- Volunteers
- 200 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Acute Urinary Retention, Benign Prostatic Hyperplasia
Prostatic Urethral Lift in Subject With Acute Urinary Retention
Assess feasibility and safety of the Prostatic Urethra Lift (PUL) procedure in patients with acute urinary retention secondary to benign prostatic hyperplasia (BPH).
- Trial name
- NCT03194737
- Testing
- UroLift System Procedure
- Where
- 6 sites in United Kingdom
- Volunteers
- 101 people
- Sponsor
- NeoTract, Inc.
Benign Prostatic Hypertrophy, Lower Urinary Tract Symptoms
Prostate Embolization for Massive Benign Prostatic Hypertrophy (BPH)
This is a prospective, open label single center feasibility study to demonstrate basic safety and effectiveness of prostate artery embolization for the treatment of symptomatic benign prostatic Hyperplasia (BPH) in a small series…
- Trial name
- NCT02676544
- Testing
- Embosphere microspheres
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- Rhode Island Hospital
Prostatic Hyperplasia, Benign Prostatic Hyperplasia
Rezum I Pilot Study for Benign Prostatic Hyperplasia
Evaluate the safety and efficacy of the Rezum System for the treatment of BPH
- Conditions
- Prostatic Hyperplasia, Benign Prostatic Hyperplasia, Adenoma, Prostatic, Prostatic Adenoma
- Trial name
- Rezum Pilot (NCT02943070)
- Testing
- Rezum System
- Where
- 3 sites in Czechia, Dominican Republic and 1 more
- Volunteers
- 50 people
- Sponsor
- Boston Scientific Corporation
Benign Prostatic Hyperplasia, Adenoma, Prostatic
Rezum FIM Optimization Study
Evaluate the effect of the NxThera BPH Rezum System on prostate tissue in subjects suffering from LUTS symptoms secondary to benign prostatic hyperplasia (BPH).
- Conditions
- Benign Prostatic Hyperplasia, Adenoma, Prostatic, Prostatic Adenoma, Prostatic Hyperplasia, Benign
- Trial name
- Rezum FIM (NCT02940392)
- Testing
- Rezum System
- Where
- Dominican Republic
- Volunteers
- 15 people
- Sponsor
- Boston Scientific Corporation