Clinical trials: Benign Tumor of Thyroid
Goiter
Subtotal Versus Total Thyroidectomy for Benign Goiter
The extent of thyroid resection in benign goiter is controversial. Potential advantages of TT over BST may include: one-stage removal of incidental thyroid cancer reported in up to 10% of operatively treated benign thyroid…
- Trial name
- NCT01273714
- Testing
- thyroid resection
- Where
- Poland
- Volunteers
- 8,006 people
- Sponsor
- Jagiellonian University
Thyroid Tumor, Breast Tumor
Detection of Benign and Malignant Thyroid and Breast Tumors by Fourier Transform Infrared Spectrometry
The purpose of this stage of study is to establish discriminant among healthy tissue, benign and malignant thyroid and breast tumors by fourier transform infrared spectrometry variables.
- Trial name
- NCT01668238
- Where
- China
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- XU Zhi
Thyroid Nodules
The Outcomes of Ultrasound-guided Thermal Ablation for Benign Thyroid Nodules
1. To evaluate the clinical outcomes of ultrasound-guided thermal ablationfor the treatment of benign thyroid nodules; 2. To develop and validate a artificial intelligence model to predict the outcomes of ultrasound-guided…
- Trial name
- NCT06340945
- Testing
- ultrasound-guided thermal ablation
- Where
- China
- Volunteers
- 1,500 people
- Sponsor
- Chinese PLA General Hospital
Thyroid Nodule, Thyroid Cancer
Cognition and QoL After Thyroid Surgery
The development of cognitive dysfunction can profoundly affect HR-QoL as well as the possibility of societal participation and ability to work, and thereby relevantly impacts prospects for cancer survivorship.
- Conditions
- Thyroid Nodule, Thyroid Cancer, Cognitive Decline, Survivorship
- Trial name
- NCT05088187
- Where
- Sweden
- Volunteers
- 320 people
- Sponsor
- Karolinska University Hospital
Thyroid Nodule
HIFU Reapplication in Benign Nodules
High Intensity Focused Ultrasound (HIFU) is a new approach in treating benign thyroid nodule without surgery. It is proven effective and safe relative to traditional surgery.
- Trial name
- NCT03331172
- Testing
- Echopulse
- Where
- Hong Kong
- Volunteers
- 28 people
- Sponsor
- The University of Hong Kong
Thyroid Nodule, Diagnoses Disease
Diagnostic Significance of CTCs in Patients With Thyroid Nodules (Circulating Tumor Cells)
Thyroid nodule patients with suggestion of fine needle aspiration biopsy (FNAB) offered by ultrasound are enrolled in the study. CTCs tested by Optimizing method and FNAB will be performed simultaneously.
- Trial name
- CTCs (NCT03772496)
- Testing
- circulating tumor cells test, Fine needle aspiration biopsy
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Cancer Institute and Hospital, Chinese Academy of Medical Sciences
Low Risk, Papillary Thyroid Cancer
Radiofrequency Ablation for Management of Benign/Indeterminate Thyroid Nodules and Low Risk Papillary Thyroid Cancers
To track the outcomes of patients who have been treated with RFA and its long-term effectiveness, and to learn more about the quality of life of patients who have received RFA in this study.
- Conditions
- Low Risk, Papillary Thyroid Cancer, Radiofrequency Ablation
- Trial name
- NCT07140757
- Testing
- Questionnaire
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- M.D. Anderson Cancer Center
Thyroid Cancer
The Evaluation of the Diagnostic Properties of Intra-operative In-situ Thyroglobin Levels of Cervical Lymph Nodes, in the Discrimination Between Benign and Malignant Lymph Nodes in Thyroid Cancer: a Prospective Multicentre Study.
Cytological examination of punctured lymph nodes is the gold standard for confirming metastatic lymph node spread of differentiated thyroid cancers.
- Trial name
- Tgcyto (NCT02602717)
- Testing
- lymph nodes cyto-punction
- Where
- France
- Volunteers
- 110 people
- Sponsor
- Assistance Publique Hopitaux De Marseille
Advanced Malignant Neoplasm, Castleman Disease
Bevacizumab and Temsirolimus Alone or in Combination With Valproic Acid or Cetuximab in Treating Patients With Advanced or Metastatic Malignancy or Other Benign Disease
This phase I trial studies the side effects and best dose of bevacizumab and temsirolimus alone or in combination with valproic acid or cetuximab in treating patients with a malignancy that has spread to other places in the body…
- Conditions
- Advanced Malignant Neoplasm, Castleman Disease, Digestive System Carcinoma, Erdheim-Chester Disease
- Trial name
- NCT01552434
- Testing
- Bevacizumab, Cetuximab, Laboratory Biomarker Analysis
- Where
- United States
- Volunteers
- 154 people
- Sponsor
- M.D. Anderson Cancer Center
Pleural Neoplasms, Mesothelioma
The ISET (Isolation by Size of Epithelial Tumor Cells) and the CellSearch Methods in Malignant Pleural Mesothelioma
Malignant pleural mesothelioma (MPM) has a growing incidence and in spite of early diagnostic, their outcome remains dismal. The evolution of MPM is often local with rare distant metastases.
- Conditions
- Pleural Neoplasms, Mesothelioma, Pneumothorax, Parathyroid Neoplasms
- Trial name
- NCT01776385
- Testing
- Blood sampling, Control Group
- Where
- France
- Volunteers
- 9 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Thyroid Nodule
The Application Value of Deep Learning-Based Nomograms in Benign-Malignant Discrimination of TI-RADS Category 4 Thyroid Nodules
This retrospective study focuses on benign and malignant classification of thyroid nodules using deep learning techniques and evaluates the value of deep learning based nomograms in the classification of TI-RADS category 4…
- Trial name
- NCT06258044
- Where
- China
- Volunteers
- 500 people
- Sponsor
- Ma Zhe
Chronic Liver Disease, Thyroid Disease
The Development of Quantitative Ultrasound Imaging Software Platform
The goal of this observational study is to compare the image differences between conventional ultrasound and artificial intelligence-based ultrasound software in conscious adults.
- Conditions
- Chronic Liver Disease, Thyroid Disease, Benign Breast Disease, Malignant Breast Neoplasm
- Trial name
- NCT05836246
- Where
- South Korea
- Volunteers
- 196 people
- Sponsor
- Seoul National University Bundang Hospital
Benign Thyroid Nodule, Suspicious Malignant Thyroid Nodule
A Prospective Trial Comparing Transoral Endoscopic Thyroidectomy Vestibular Approach (TOETVA) and Conventional Open Thyroidectomy
To determine if transoral endoscopic thyroidectomy vestibular approach (TOETVA) is a safe and effective procedure compared to traditional open thyroidectomy.
- Trial name
- NCT06225765
- Testing
- Transoral endoscopic thyroidectomy vestibular approach (TOETVA), Traditional Open Thyroidectomy
- Where
- Hong Kong
- Volunteers
- 40 people
- Sponsor
- Tseung Kwan O Hospital, Hong Kong
Thyroid Cancer, Nodule Solitary Thyroid
Differentiation of Benign From Malignant Thyroid Nodules Using Diffuse Reflectance Spectroscopy
Patients with thyroid nodules are currently investigated with ultrasound with or without biopsy. Despite these investigations, a subset of patients remain "indeterminate" whereby a cancer can neither be diagnosed nor ruled out …
- Trial name
- NCT07124065
- Testing
- Diffuse reflectance spectroscopy
- Where
- United Kingdom
- Volunteers
- 50 people
- Sponsor
- Imperial College London
Benign Thyroid Gland Neoplasm, Recurrent Thyroid Gland Carcinoma
Radiofrequency Ablation for the Treatment of Benign or Low Risk Thyroid Nodule
This phase IV trial studies the effect of radiofrequency ablation in treating patients with benign or low risk thyroid nodule. Radiofrequency ablation uses a needle to deliver a high-frequency electric current to kill tumor cells…
- Conditions
- Benign Thyroid Gland Neoplasm, Recurrent Thyroid Gland Carcinoma, Thyroid Gland Follicular Tumor of Uncertain Malignant Potential, Thyroid Gland Nodule
- Trial name
- NCT05003856
- Testing
- Quality-of-Life Assessment, Radiofrequency Ablation
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- M.D. Anderson Cancer Center
Benign Solitary Solid, Cystic Thyroid Nodules
Laser Therapy of Benign Thyroid Nodules
Nodular goitre is common in the general population and less than 5% of the patients who undergo surgery for solitary thyroid nodules have cancer, in absence of clinical suspicion.
- Trial name
- NCT00150150
- Testing
- Interstitial laser photocoagulation
- Where
- Denmark
- Volunteers
- 70 people
- Sponsor
- Odense University Hospital
Thyroid Nodule
Ultrasound-guided Percutaneous Microwave Ablation for Benign Thyroid Nodules
Percutaneous microwave ablation(MWA) was reported as an effective modality for the management of thyroid nodules(TNs). This study aims to validate MWA as a feasible approach for patients with TNs for whom surgery is…
- Trial name
- NCT03057925
- Testing
- Microwave Ablation
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Wenjun Wu
Thyroid Nodule
Application of Ultrasonic Gray-scale Ratio in Differentiating Benign From Malignant Thyroid Nodules.
According to the grades of echogenicity to evulated thyroid nodules is a subjective process and is thus influenced by the observer's judgement.
- Trial name
- NCT03700762
- Testing
- ultrasound gray-scale ratio
- Where
- China
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- First People's Hospital of Hangzhou