Clinical trials: Beryllium Disease
Sarcoidosis, Berylliosis
Identifying Shared Genetic Susceptibility Regions in Chronic Beryllium Disease and Sarcoidosis
Granulomatous lung diseases are diseases in which inflamed clusters of white cells, known as granulomas, form in lung tissue. Chronic beryllium disease (CBD) and sarcoidosis are two granulomatous diseases that share similar…
- Trial name
- NCT00560989
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- National Jewish Health
Berylliosis, Beryllium Disease
Beryllium Infliximab Study: Clinical Interventional Trial
The goal of this research study is to test the clinical effectiveness of a drug called infliximab (Remicade) in chronic beryllium disease (CBD).
- Trial name
- BISCIT (NCT00111917)
- Testing
- Infliximab
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Maier, Lisa, M.D.
Lung Cancer, Chronic Obstructive Pulmonary Disease
Blood, Hair and Lung Concentrations of Metals and Metalloids in Patients With Lung Cancer or Chronic Obstructive Pulmonary Disease
Prospective research to study the relationship between concentrations of metals/metalloids in blood, hair and lung tissue with the occurence of lung cancer or chronic obstructive pulmonary disease.
- Conditions
- Lung Cancer, Chronic Obstructive Pulmonary Disease, Emphysema, Lung Surgery
- Trial name
- Métaux/Poumons (NCT01949181)
- Testing
- Lung surgery
- Where
- 2 sites in France
- Volunteers
- 251 people
- Sponsor
- Hopital Foch
Pulmonary Sarcoidosis, Chronic Beryllium Disease
Study Comparing Chronic Beryllium Disease to Pulmonary Sarcoidosis
Inhalation of beryllium can induce specific sensitization and diffuse pulmonary granulomatosis called chronic beryllium disease (CBD).
- Trial name
- BERYSARC (NCT06113991)
- Where
- France
- Volunteers
- 200 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Chronic Beryllium Disease (CBD), Beryllium Sensitization (BeS)
The Role of JAK2 in Alveolar Macrophages (AM's) in Chronic Beryllium Disease (CBD)
Current studies suggest that alveolar macrophages (AM) act as silencers of most immune responses in the lung. However, in pathological conditions, such as asthma, hypersensitivity pneumonitis, and sarcoidosis, AMs become involved…
- Trial name
- NCT02596347
- Testing
- Blood draw, bronchoscopy
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- National Jewish Health
Chronic Beryllium Disease
Targeting Oxidative Stress in Chronic Beryllium Disease
The purpose of this study is to understand if a drug called mesalamine helps to control inflammation associated with chronic beryllium disease (CBD).
- Trial name
- NCT01088243
- Testing
- Mesalamine
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- National Jewish Health
Chronic Beryllium Disease
Exposure in Epigenetic Regulation of Immune Response in Chronic Beryllium Disease (CBD)
This study will provide important results for each aim, while also providing an integrative transcriptional and epigenomic profile of CBD.
- Trial name
- BeEpiGen (NCT02604693)
- Testing
- Nothing
- Where
- United States
- Volunteers
- 148 people, healthy volunteers welcome
- Sponsor
- National Jewish Health