Clinical trials: Bifidobacterium
Indirect Hyperbilirubinemia
Efficacy of Bifidobacterium Animalis Subsp. Lactis in the Treatment of Indirect Hyperbilirubinemia in Term Neonates
This study aims to evaluate the effectiveness of adjunctive oral Bifidobacterium animalis subsp. lactis in term neonates with indirect hyperbilirubinemia receiving phototherapy.
- Trial name
- NCT07773012
- Testing
- Bifidobacterium animalis subsp. lactis, Standard Phototherapy
- Where
- Vietnam
- Volunteers
- 90 people
- Sponsor
- Can Tho University of Medicine and Pharmacy
Healthy
Impact of Native Chicory Inulin on Change and Persistence of Gut Microbiota
The main aim of this study is to investigate differences in rate, extent of change and persistence of the gut microbiota in healthy adult volunteers in response to native chicory inulin.
- Trial name
- INFLUX (NCT06528041)
- Testing
- Inulin, Maltodextrin
- Where
- United States
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Purdue University
Oral Mucositis, Quality of Life
Effect of Live Combined Bifidobacterium,Lactobacillus and Enterococcus Capsules on Oral Mucositis in Nasopharyngeal Carcinoma Patients Receiving Radiotherapy.
Effect of Live Combined Bifidobacterium,Lactobacillus and Enterococcus Capsules on Oral Mucositis in Nasopharyngeal Carcinoma Patients Receiving Radiotherapy.
- Trial name
- NCT03112837
- Testing
- Lactobacillus, Bifidobacterium and Enterococcus
- Where
- China
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Jiangxi Provincial Cancer Hospital
Obesity, Insulin Resistance
Smectite Gel and Probiotic for Obesity and Insulin Resistance
Probiotics are defined as live microorganisms that, when administered in adequate amounts, confer a health benefit on the host. Smectite is a natural silicate clay belonging to the dioctahedral smectite class formed from…
- Conditions
- Obesity, Insulin Resistance, Insulin Sensitivity, Type2 Diabetes Mellitus
- Trial name
- NCT04293731
- Testing
- Symbiter-Smectite
- Where
- Ukraine
- Volunteers
- 55 people
- Sponsor
- Bogomolets National Medical University
Colic, Infantile, Probiotic
NEOBIFI: Clinical Trial for the Prevention and/or Reduction of the Incidence of Colics in Infants
Infant colics represent a clinical condition in childhood, characterized by an uncontrollable crying that occurs without any apparent organic cause.1 They can be associated with face redness, closed fists, thighs flexion…
- Conditions
- Colic, Infantile, Probiotic, Gut Microbiome, Bifidobacterium Breve
- Trial name
- NEOBIFI (NCT03219931)
- Testing
- Bifidobacterium breve BR03 and Bifidobacterium breve B632
- Where
- Italy
- Volunteers
- 320 people, healthy volunteers welcome
- Sponsor
- Azienda Ospedaliero Universitaria Maggiore della Carita
Infant Development, Safety Issues
Safety of Bifidobacterium Breve PS1 for Infants
The objective of this work was the characterization of the probiotic potential of Bifidobacterium breve PS1, a strain originally isolated from human milk.
- Trial name
- NCT05973812
- Testing
- Infant formula supplemented with Bifidobacterium breve PS1, Infant formula NOT supplemented with Bifidobacterium breve PS1
- Where
- 3 sites in Spain
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Universidad Complutense de Madrid
Dental Caries, Oral Health
Effect of Probiotics Containing Yogurts on the Composition of Biofilms in Patients Under Orthodontic Treatment
Aim: To assess in vivo if the intake of yogurt containing Bifidobacterium animalis ssp. lactis DN- 1173010 probiotic for a period of 2 weeks affects the salivary levels or biofilms of mutans streptococci and the lactobacilli of…
- Trial name
- NCT01657539
- Testing
- Yogurt containing probiotics
- Where
- Brazil
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Federal University of Pelotas
Prebiotics, Microbiota
Mixture of Prebiotics on Intestinal Microbiota of Patients Receiving Abdominal Radiotherapy.
Abdominal and pelvic radiotherapy (RT) reduces the renewal capacity of the epithelium. Rectal biopsies obtained from patients receiving pelvic RT have revealed atrophy of surface epithelium, acute cryptitis, crypt abscesses…
- Conditions
- Prebiotics, Microbiota, Radiation Therapy Complication, Endometrial Neoplasms
- Trial name
- NCT01549782
- Testing
- Inulin and Fructo-oligosaccharide, Maltodextrine
- Where
- Spain
- Volunteers
- 40 people
- Sponsor
- Hospital General Universitario Gregorio Marañon
Abdominal Pain, Abdominal Discomfort
Pilot Study Studying Physiological Effects of Probiotic Pills in Patients With Abdominal Pain/Discomfort and Bloating
We are conducting a study to learn if probiotics, which are live bacteria found in food like yogurt and cheese, will improve symptoms of abdominal pain.
- Conditions
- Abdominal Pain, Abdominal Discomfort, Bloating, Functional Bowel Disorders
- Trial name
- NCT01064661
- Testing
- Single probiotic arm of L-NCFM alone, Blend probiotic arm of L-NCFM and B-LBi07
- Volunteers
- 22 people
- Sponsor
- University of North Carolina, Chapel Hill
Duration of Parenteral Nutrition
Digestive and Nutritional Effects of Probiotics Supplementation in Premature Newborns
Symbiotic interaction between probiotics ("Living alimentary microbials supplemental, affecting positively host by improving intestinal microbial equilibrium" (Fuller, 1989)) and human digestive tract was amply experimented and…
- Trial name
- NCT00290576
- Testing
- Probiotics supplementation until weight reaches 1800g (Bifidobacterium Longum and Lactobacillus GG )
- Where
- France
- Volunteers
- 127 people
- Sponsor
- Nantes University Hospital
Women, Rheumatoid Arthritis
Determination of the Biological Activity of Serum From Patients
The main objective of the study is to determine the influence of patient sera before and after probiotic intervention on the behavior of bone cells (osteoblasts and osteoclasts).
- Trial name
- nutricell3 (NCT04696718)
- Testing
- daily supplementation
- Where
- France
- Volunteers
- 20 people
- Sponsor
- Adeline BLOT
Healthy Volunteers
Effects of Bifidobacterium Longum BB536 on Incidence of Acute Diarrhea and/or Respiratory- Related Illnesses in Children
This project aims to study the benefits of probiotics namely Bifidobacterium longum BB536 in prevention of acute diarrhea and/or respiratory-related illnesses, which are found common among children in Malaysia aged from 2 to 6…
- Trial name
- NCT02434042
- Testing
- BB536
- Where
- Malaysia
- Volunteers
- 520 people, healthy volunteers welcome
- Sponsor
- Universiti Sains Malaysia
Healthy Adult Volunteer
The Effect of Bifidobacterium Probiotics on Gut Microbiota Changes in Healthy Adults During Short-term Travel Along the Silk Road
Journeying along the historic Silk Road exposes travelers to dramatic dietary shifts, unfamiliar microbial environments, and the physical stresses of long-distance travel-all known to disrupt gut health and cause gastrointestinal…
- Trial name
- NCT07182500
- Testing
- Probiotic
- Where
- 2 sites in China, Malaysia
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Universiti Sains Malaysia
Functional Constipation
Co-supplementation With Bifidobacterium Longum W11 and Colopectin for Maintenance Therapy in Children With Functional Constipation
Functional constipation is a common condition in children and often requires prolonged maintenance treatment with macrogol. This randomized, double-blind, placebo-controlled trial will evaluate whether co-supplementation with…
- Trial name
- NCT07536698
- Testing
- Bifidobacterium longum W11 (Bowell®) + Colopectin (Colopectin®)
- Volunteers
- 100 people
- Sponsor
- Liaquat University of Medical & Health Sciences
Food Allergy in Infants
The Role of Bifidobacterium Intervention in Food Allergic Infants
Infant food protein allergy is the most common allergic disease in children, which can lead to infantile-specific dermatitis, intestinal inflammation, and so on.
- Trial name
- NCT05965063
- Testing
- Bifidobacterium M-16V, allergy food avoidance
- Where
- China
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Ruijin Hospital
Functional Constipation
The Effect of Bifidobacterium Lactis and Inulin on Functional Constipation
The aim of this study is to asses the effect of Bifidobacterium lactis and Inulin on functional constipation in children
- Trial name
- NCT01913665
- Testing
- B.lactis, Inulin, B.Lactis +Inulin
- Volunteers
- 200 people
- Sponsor
- Eskisehir Osmangazi University
Fecal Microflora in the Formula Fed Premature Infant
The Impact of Oligosaccharides and Bifidobacteria on the Intestinal Microflora of Premature Infants
The purpose of this study is to see whether dietary supplements can change the germs in the intestines of premature infants to be more like those of healthy breast fed term babies.
- Trial name
- NCT00810160
- Testing
- ProlactPlus, GOS galacto-oligosaccharides, Bifidobacterium infantis
- Where
- United States
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Functional Gastrointestinal Disorders, Functional Abdominal Pain
Effect of 35624® Alflorex® in Functional Gastrointestinal Disorders (FGIDs) in Children.
The aim of this study is to evaluate the effect of supplementation with Bifidobacterium longum 35624® Alflorex® on frequency and severity of symptoms of abdominal pain using an adapted Irritable Bowel Symptom Severity Scoring…
- Trial name
- NCT04922476
- Testing
- Alflorex®
- Where
- Chile
- Volunteers
- 65 people
- Sponsor
- PrecisionBiotics Group Ltd.
Irritable Bowel Syndrome
The Effects of Bifidobacterium Breve Bif195 for Diarrhea-predominant Irritable Bowel Syndrome
The purpose of this study is to investigate if the probiotic Bifidobacterium breve Bif195 (Bif195) will result in improvement in clinical outcome in patients with diarrhea-predominant irritable bowel syndrome (IBS).
- Trial name
- NCT04808271
- Testing
- Bifidobacterium breve Bif195
- Where
- 2 sites in Denmark
- Volunteers
- 61 people
- Sponsor
- Hvidovre University Hospital
Periodontitis, Probiotics
Effects of Probiotic Therapy in the Treatment of Periodontitis.
The aim of this study is to evaluate the effect of the probiotic therapy as an adjunct to non-surgical periodontal treatment in patients diagnosed with Generalized Chronic Periodontitis.
- Trial name
- NCT03408548
- Testing
- Scaling root planning, Probiotic
- Where
- Brazil
- Volunteers
- 41 people
- Sponsor
- University of Sao Paulo