Clinical trials: Bifidobacterium
Celiac Disease
Bifidobacterium Infantis NLS Super Strain for Celiac Disease Patients on a Gluten-free Diet With Persistent Gastrointestinal Symptoms
The primary purpose of this randomized, double-blinded, placebo-controlled, crossover clinical trial is to evaluate the efficacy of dietary supplementation with Bifidobacterium infantis NLS super strain among celiac disease…
- Trial name
- NCT03271138
- Testing
- Bifidobacterium infantis NLS super strain (Natren LIFE START®2)
- Where
- Argentina
- Volunteers
- 18 people
- Sponsor
- Global Institute of Probiotics
Subjective Sleep Quality, Objective Sleep Quality
Effect of B. Longum 1714™ on Sleep Quality
The aim of this study is to evaluate the effect of supplementation with the B. longum 1714™ strain on subjective and objective sleep quality in healthy participants.
- Trial name
- NCT04167475
- Testing
- Probiotic capsule
- Where
- Ireland
- Volunteers
- 89 people, healthy volunteers welcome
- Sponsor
- PrecisionBiotics Group Ltd.
Hyperlipidemias
Effect of Different Probiotic Strains in Hypercholesterolemic Patients
Regular probiotic use for 8 weeks was evaluated in individual with mild to moderate hyperlipidemia. Current study have been determined the use of different probiotics strains on lipid parameters such as; total cholesterol, HDL…
- Trial name
- NCT04701775
- Testing
- Only Lactobacillus rhamnosus GG strains, Combined Lactobacillus acidophilus and Bifidobacterium animalis subsp.lactis strains
- Where
- Cyprus
- Volunteers
- 51 people
- Sponsor
- Eastern Mediterranean University
Healthy Aging, Anti Aging
iVS-1 Probiotic Intervention Targeting Biological Aging in Midlife Adults
This study is a randomized, double-blind, placebo-controlled clinical trial designed to evaluate the effects of Bifidobacterium adolescentis (iVS-1) supplementation on biological aging markers, metabolic health, and functional…
- Trial name
- VITAL (NCT07407894)
- Testing
- Bifidobacterium adolescentis iVS-1
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Synbiotic Health
Gastrointestinal Diseases
The Effects of an Infant Formula Containing Probiotic CECT7210 on Gastrointestinal Health
The purpose of this study is to determine whether an infant formula supplemented with a new probiotic CECT7210, is effective in reducing the incidence of infections, specially the gastrointestinal ones.
- Trial name
- GO-INF (NCT02096302)
- Testing
- Infant Formula with a novel probiotic CECT7210, Standard formula
- Where
- 3 sites in Spain
- Volunteers
- 194 people, healthy volunteers welcome
- Sponsor
- Laboratorios Ordesa
Changes in Gut Microbiota, Gut Metabolites, Respiratory Symptoms, and Well-being Index
A Probiotic for Health Outcomes in Short-Term Overseas Travel
With the improvement of living standards, travel has become a common form of leisure. However, travelers often face changes in living environments, dietary habits, and sleep schedules, all of which can impact the gut microbiota…
- Trial name
- NCT07705659
- Testing
- Bifidobacterium longum, Maltodextrin
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- DiproBio (Shanghai) Co., Ltd.
Infant, Newborn, Immunity
The Bloom Infant Probiotic (BIP) Study
The goal of this clinical trial is to investigate whether administering a probiotic (Infloran®) to infants who received antibiotics in the first 28 days of life can restore or enhance their immune response to routine vaccines.
- Conditions
- Infant, Newborn, Immunity, Immunisation, Antibiotic Treatment
- Trial name
- BIP (NCT07189390)
- Testing
- Probiotic
- Where
- 2 sites in Australia
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- South Australian Health and Medical Research Institute
Allergic Rhinitis, Allergic Rhinitis (AR)
Effect of Combined Probiotics and Vitamin D on Symptoms of Allergic Rhinitis
The goal of this clinical trial is to learn if taking probiotics, vitamin D, or both together can help lower symptoms of allergic rhinitis (AR) and improve quality of life in adults.
- Trial name
- NCT07115342
- Testing
- Standard Allergic Rhinitis Treatment, Combined Vitamin D and Probiotics Supplementation
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Tanta University
Hiv, Vaccine Reaction
B. Infantis Supplementation to Improve Immunity in Infants Exposed to HIV
The primary objectives of this study are to evaluate the effect of early-life B. infantis Rosell®-33 supplementation in infants exposed to HIV on: gut microbiome composition and diversity at 4 weeks of life markers of intestinal…
- Conditions
- Hiv, Vaccine Reaction, Microbial Colonization, Infant Development
- Trial name
- BifIID (NCT05923333)
- Testing
- B. infantis Rosell®-33
- Where
- South Africa
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Cape Town
Disorder of Stomach Function and Feeding Problems in Newborn, Feeding and Eating Disorders of Childhood
Effect of Early Oral Triple Viable Bifidobacterium Intestinal Flora in Preterm
Gut of newborn preterm is sterile, immediately by the mother and the surrounding environment from microbial colonization. As the effects of diet, intestinal flora is rapidly changed.
- Trial name
- NCT02060084
- Testing
- a control group, a probiotic-supplemented group
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Wang Hua
Obesity
Study of Efficacy of a Probiotic and Postbiotic in Overweight and Obese Individuals
The study's main objective is to investigate the effect of a probiotic (live bacteria), postbiotic (heat-treated bacteria) on obesity parameters.
- Trial name
- Obelix (NCT05440630)
- Testing
- Probiotics, Postbiotic
- Where
- Mexico
- Volunteers
- healthy volunteers welcome
- Sponsor
- The Archer-Daniels-Midland Company
Confinement and Isolation
A Counter Measure for the Effects of Immune and Microbiome Changes in Environments With Limited ANtigen Diversity (ICELAND-TWO)
There is evidence to indicate that the gut microbiota has an effect on mental well-being and stress behaviours. This is highly relevant to both life on earth and spaceflight missions, in which mental well-being is crucial to…
- Trial name
- ICELAND-2 (NCT03746145)
- Testing
- Bifidobacterium longum 1714
- Where
- Antarctica
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University Hospital Tuebingen
Obesity
Influence of Probiotic and Symbiotic in Body Weight, Blood Sugar and Lipemia of Obese Women
The purpose of this study is to evaluate whether gut microbiota modulation by probiotic and symbiotic contribute with weight loss and improvement of metabolic parameters in women with obesity.
- Trial name
- NCT02505854
- Testing
- Probiotic, Symbiotic
- Where
- Brazil
- Volunteers
- 32 people
- Sponsor
- Universidade Federal do Rio de Janeiro
Berberine Hydrochloride
Effectiveness and Safety of Berberine Hydrochloride and Bifidobacterium in People With Abnormal Glucose Level
The aim of this study is to assess the beneficial effects of Bifidobacterium and Berberine Hydrochloride on lowering glucose and delaying progress to diabetes in patients with prediabetes and to detect the potential mechanism.
- Trial name
- NCT03330184
- Testing
- Berberine Hydrochloride group, Bifidobacterium group, Berberine Hydrochloride and Bifidobacterium group
- Volunteers
- 300 people
- Sponsor
- Xijing Hospital
Chronic Periodontitis
Probiotics Effects to Initial Periodontal Treatment
The aim of this study is to evaluate the clinical and microbiological effects of Bifidobacterium animalis subsp. lactis DN-173010 containing yoghurt as an adjunct to mechanical periodontal treatment.
- Trial name
- NCT05408364
- Testing
- probiotic or natural yoghurt, SRP
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Marmara University
Attention Deficit Hyperactivity Disorder
Impact of Probiotics on Children With ADHD
This study investigates WecProB (Bifidobacterium animalis subsp. lactis and Lacticaseibacillus rhamnosus) to evaluate their potential to improve symptoms and safety in children with ADHD.
- Trial name
- NCT06348121
- Testing
- Probiotic
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Wecare Probiotics Co., Ltd.
Male Infertility
Effect of Antioxidant Probiotic Administration on Seminal Quality and Reproductive Outcomes.
The quality of semen plays a fundamental role in correct fertilization and development of normal embryos that result in a live birth. Unfortunately, semen quality has declined during the last decades, and reduced more and more.
- Trial name
- NCT04585984
- Testing
- Experimental - Probiotic
- Where
- Spain
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Fundación IVI
Cancer
Lactulose to Improve Gut Health in Cancer Patients Receiving Immunotherapy
The purpose of this study is to see if lactulose can improve the effectiveness of immunotherapy in patients with advanced cancer.
- Trial name
- (BLOOM) (NCT07354100)
- Testing
- Lactulose
- Where
- United States
- Volunteers
- 55 people
- Sponsor
- University of Chicago
Safety Issues
Safety Evaluation of Lactobacillus Salivarius AP-32 and Bifidobacterium Animalis Subsp. Lactis CP-9 in Healthy Infants.
This is a three-arm, double-blind, placebo-controlled study to investigate the safety of Lactobacillus salivarius AP-32 and Bifidobacterium animalis subsp. lactis CP-9 used individually in healthy infants.
- Trial name
- NCT04140604
- Testing
- Lactobacillus salivarius AP-32, Bifidobacterium animalis subsp. lactis CP-9
- Where
- Taiwan
- Volunteers
- 89 people, healthy volunteers welcome
- Sponsor
- Hsieh-Hsun Ho
Preterm Infants
Bifidobacterium Supplementation for Very Low Birth Weight Infants
Probiotic supplementation to preterm infants have been reported to be beneficial in neonatal intensive care unit (NICU). Our pilot study also showed accelerated feeding in preterm infants who received Bifidobacterium bifidum…
- Trial name
- Bifido(RCT) (NCT01375309)
- Testing
- Bifidobacterium bifidum supplementation
- Where
- Japan
- Volunteers
- 246 people
- Sponsor
- Tokyo Women's Medical University