Clinical trials: Bifidobacterium
Defecation Irregularity
Effects of Fermented Dairy Products on Defecation Changes Through Gut Microbiota
The investigators recruited participants aged 20-65 years who did not have gastrointestinal diseases and who were not taking medication for digestive symptoms (e.g., gastric acid inhibitors, antibiotics, sterilization…
- Trial name
- NCT06862310
- Testing
- yogurt intervention
- Where
- Taiwan
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Taipei Medical University
Febrile Neutropenia, Neutropenia
Prevention of Febrile Neutropenia by Synbiotics in Pediatric Cancer Patients
Febrile neutropenia (FN) is a major life-threatening treatment complication in cancer patients undergoing intensive chemotherapy. Endogenous flora is considered to be one of the main sources of infections during neutropenia.
- Conditions
- Febrile Neutropenia, Neutropenia, Infection in an Immunocompromised Host, Cancer
- Trial name
- FENSY (NCT02544685)
- Testing
- Probio-Fix Inum, Beneo Synergy 1
- Where
- Slovakia
- Volunteers
- 120 people
- Sponsor
- S&D Pharma SK s.r.o.
Non-small Cell Lung Cancer
Lactobacillus Bifidobacterium V9(Kex02)Improving the Efficacy of Carilizumab Combined With Platinum in Non-small Cell Lung Cancer Patients
Human microbes have been called "the second genome of humanity".On May 13,2016,the White House launched the National Microbiome Initiative (NMI), with an estimated investment of us $521 million, to elevate microbiome research to…
- Trial name
- NCT05094167
- Testing
- V9
- Where
- China
- Volunteers
- 46 people
- Sponsor
- Jiangxi Provincial Cancer Hospital
Functional Constipation
Effect of Probiotics on Functional Constipation in Adults
Introduction: Functional constipation is a symptom-based gastrointestinal disorder without an organic origin (eg, bowel obstruction). It has a prevalence of 14% in adults.
- Trial name
- PROBCON (NCT04437147)
- Testing
- 3 Billion UFC strains of probiotics, 8 Billion UFC strains of probiotics
- Where
- Brazil
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Luciane Cruz Lopes
Irritable Bowel Syndrome, Irritable Bowel Syndrome With Diarrhea (IBS-D)
Efficacy of Repeated Transcranial Magnetic Stimulation Combined With a Live Probiotic Tablet (Combined Bifidobacterium, Lactobacillus, Enterococcus and Bacillus Cereus Tablets, Live) in Diarrhea-Predominant Irritable Bowel Syndrome (IBS-D)
To evaluate the overall efficacy of repeated Transcranial Magnetic Stimulation(rTMS) combined with a Live Probiotic tablet (Combined Bifidobacterium, Lactobacillus, Enterococcus and Bacillus cereus Tablets, Live) in…
- Conditions
- Irritable Bowel Syndrome, Irritable Bowel Syndrome With Diarrhea (IBS-D), Repetitive Transcranial Magnetic Stimulation (rTMS), Probiotic
- Trial name
- NCT06960369
- Testing
- rTMS combined with Live Probiotic tablet
- Where
- China
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- The First Affiliated Hospital of Soochow University
Healthy
Study to Investigate the Potential of Probiotics in Yogurt
The purpose of this study is to determine if the consumption of a yogurt drink containing a high dose of probiotics decreases absences, due to illnesses, in daycare centers for children between the ages of 1 and 3.
- Trial name
- SIPPY (NCT00492583)
- Testing
- Bifidobacterium lactis (BB-12)
- Where
- United States
- Volunteers
- 182 people, healthy volunteers welcome
- Sponsor
- Georgetown University
Surgery, Infection
Efficacy of Bifidobacterium Lactis CCT 7858 in Adults Using Antibiotics
To evaluate the effectiveness of the probiotic Bifidobacterium lactis CCT 7858 in preventing and / or improving gastrointestinal symptoms in adults using antibiotics.
- Trial name
- NCT04742322
- Testing
- Bifidobacterium Lactis CCT7858, Maltodextrin
- Where
- Brazil
- Volunteers
- 116 people
- Sponsor
- Universidade do Extremo Sul Catarinense - Unidade Academica de Ciecias da Saude
Bacterial Infections
Effect of Bifidobacterium Breve PRL2020 (an Amoxicillin-clavulanate-resistant Strain) on Gastrointestinal Symptoms and Gut Microbiota Composition in Children Treated With Amoxicillin or Amoxicillin/Clavulanate
Amoxicillin or Amoxicillin/Clavulanic acid antibiotic therapy has been shown to be associated with disrupting the microbiota population particularly Bifidobacterium, which may have further GI clinical implications.
- Trial name
- NCT05840588
- Testing
- Antibiotic Treatment, Probiotic Bifidobacterium breve PRL2020 (Brevicillin®) treatment
- Where
- Italy
- Volunteers
- 121 people
- Sponsor
- Liaquat University of Medical & Health Sciences
Periodontal Health, Dental Plaque Accumulation
Effects of Probiotics on Oral Health
Some probiotics have been shown to have preventive effects on infectious diseases and allergies. Because their long-term enhancement of the immune responses of children, they have been recommended for infants in some countries.
- Trial name
- NCT02444182
- Testing
- Probiotics
- Where
- Kuwait
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Kuwait University
Fibromyalgia, Fibromyalgia Syndrome
PRL2019 in the Treatment of Juvenile Fibromyalgia
Juvenile Fibromyalgia Syndrome (JFS) is a chronic condition affecting children and adolescents, characterised by widespread musculoskeletal pain and a significant impact on daily life and quality of life.
- Trial name
- IGG-microbiota (NCT07738926)
- Testing
- Bifidobacterium adolescentis PRL2019
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- Istituto Giannina Gaslini
Prediabetes
Effects of Berberine Hydrochloride and Bifidobacterium in Prediabetes Prevention and Treatment
The aim of this study is to assess the beneficial effects of Bifidobacterium and Berberine Hydrochloride on lowering glucose and delaying progress to diabetes in patients with prediabetes and to detect the potential mechanism.
- Trial name
- NCT02082756
- Testing
- Bifidobacterium viable pharmaceutics, Berberine Hydrochloride
- Where
- 4 sites in China
- Sponsor
- Xijing Hospital
IBS in Celiac Desease
Probiotics for the Treatment of Irritable Bowel Syndrome in Celiac Patients
Probiotics play an important role in preventing overgrowth of potentially pathogenic bacteria and maintaining the integrity of the gut mucosal barrier.
- Trial name
- ProCel (NCT01699191)
- Testing
- Probiotic
- Where
- Italy
- Volunteers
- 120 people
- Sponsor
- University of Bari
Gastrointestinal Tract Infections, Respiratory Tract Infections
Bifidobacterium Animalis Subsp. Lactis in Prevention of Common Infections in Healthy Children Attending Day Care Centers
Hypothesis: Use of Bifidobacterium animalis subsp. lactis can effectively prevent common infections (gastrointestinal and respiratory) in healthy children who attend day care centre This study is a prospective, randomized, double…
- Trial name
- PROBBIC (NCT01702753)
- Testing
- Bifidobacterium animalis subsp. lactis
- Where
- Croatia
- Volunteers
- 250 people
- Sponsor
- Children's Hospital Zagreb
Preterm Infants
Early Administration of Bifidobacterium to Very Low Birth Weight Infants
To evaluate the effects of early administration of probiotics on acceleration of enteral feeding, and on growth of very low birth weight infants, newborn infants with birth weight less than 1500g are administered Bifidobacterium…
- Trial name
- NCT01330095
- Testing
- Administration of Bifidobacterium bifidum
- Where
- Japan
- Volunteers
- 36 people
- Sponsor
- Tokyo Women's Medical University
Obesity
Effect of Bifidobacterium Breve B-3 on Body Fat in Obese Adults
Comparison of a randomized, double-blind, and control-group study for the effect of oral ingestion of Bifidobacterium breve B-3 on body fat reduction in obese adults
- Trial name
- NCT03774381
- Testing
- Bifidobacterium breve B-3, Control group
- Where
- South Korea
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Pusan National University Yangsan Hospital
Overweight, Obesity
Effect of Study Probiotics on Body Fat Mass in Overweight and Obese Individuals Following Healthy Lifestyle Intervention
A randomized, double-blind, placebo-controlled, multi-center, parallel group study on overweight and obese individuals following healthy lifestyle consisting of calorie-reduced diet (20% calorie restriction) and increase in daily…
- Trial name
- QLSlimCapHL (NCT03934229)
- Testing
- Daily intake of study product
- Where
- 7 sites in France, Spain
- Volunteers
- 418 people, healthy volunteers welcome
- Sponsor
- Danisco France SAS
Gingivitis
Probiotic Yoghurt Effect on Experimental Gingivitis
The aim of this study was to evaluate the effects of probiotic yoghurt on the development of gingival inflammation. Fifty-one periodontally healthy individuals were given standard oral hygiene instructions and randomly divided…
- Trial name
- NCT02546206
- Testing
- Probiotic Yoghurt, Natural Yoghurt
- Where
- Turkey (Türkiye)
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Marmara University
Acute Pancreatitis
Therapeutic Effect of Bifidobacterium Longum in Patients with Acute Pancreatitis: a Randomized, Double-Blind, Placebo-Controlled Trial
The purpose of this clinical trial is to investigate the impact of Bifidobacterium longum(BL) on the clinical prognosis of patients with acute pancreatitis(AP), to analyze the correlation between BL and intestinal barrier…
- Trial name
- NCT06639516
- Testing
- Bifidobacterium longum, Standard clinical treatment
- Where
- China
- Volunteers
- 60 people
- Sponsor
- The First Affiliated Hospital of Nanchang University
Acute Watery Diarrhea
Bacillus Clausii Versus Multistrain Probiotics for Acute Watery Diarrhea in Children
This randomized controlled trial will compare Bacillus clausii (Enterogermina) and a multistrain probiotic preparation (Ecotec) in children aged 1-5 years with acute watery diarrhea.
- Trial name
- NCT07660367
- Testing
- Enterogermina, Ecotec
- Where
- Pakistan
- Volunteers
- 138 people
- Sponsor
- Children Hospital and Institute of Child Health, Lahore
Immune System
Dose Response Study of a Fermented Yogurt on the Immune System and Gut Health
The purpose of this study is to determine the dose-response effect of a yogurt containing a combination of bifidobacterium Lactis (BB-12) and Lactobacillus Acidophilus (LA-5) and green tea extract on markers of the immune system…
- Trial name
- PRO (NCT00730626)
- Testing
- Yogurt with 1X10E9 BB-12 and LA-5, Yogurt with 1X10E10 BB-12 and LA-5
- Where
- Canada
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Laval University