Clinical trials: Bifidobacterium
Gut Microbiota, Hepatocellular Carcinoma
Clinical Study on BIFICO Accelerating Postoperative Liver Function Recovery in Patients With Hepatocellular Carcinoma
On the basis of previous studies, this study intends to explore the effect of BIFICO on liver function recovery of patients with hepatocellular carcinoma (HCC) after surgery, so as to provide a new method for accelerating liver…
- Conditions
- Gut Microbiota, Hepatocellular Carcinoma, Bifidobacterium
- Trial name
- NCT05178524
- Testing
- BIFICO
- Where
- China
- Volunteers
- 180 people
- Sponsor
- Tongji Hospital
Irritable Bowel Syndrome, Abdominal Pain
Bifidobacterium Infantis M-63 Improves Mental Health in Irritable Bowel Syndrome Developed After a Major Flood Disaster
A 3-month study was conducted in flood victims from affected villages in the Tumpat district, Kelantan. Participants were given either probiotic, Bifidobacterium infantis M63 (M-63 group) or no probiotics (control group) for…
- Conditions
- Irritable Bowel Syndrome, Abdominal Pain, Small Intestinal Bacterial Overgrowth
- Trial name
- NCT03318614
- Testing
- Probiotics M-63, Control group
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Universiti Sains Malaysia
Type 2 Diabetes Mellitus
Effects of Berberine Hydrochloride and Bifidobacterium in Diabetes Mellitus Prevention and Treatment
The aim of this study is to assess the beneficial effects of Bifidobacterium Hydrochloride and Berberine on lowering glucose in patients with type 2 diabetes mellitus and to detect the potential mechanism.
- Trial name
- NCT02084004
- Testing
- Bifidobacterium viable pharmaceutics, Berberine Hydrochloride
- Where
- 4 sites in China
- Sponsor
- Xijing Hospital
Major Depression
Effect of Psychobiotics With Standard Antiddepressants in Treatment of Major Depressive Disorder
The goal of this clinical trial is to learn whether adding psychobiotics (a combination of Lactobacillus helveticus and Bifidobacterium longum) to standard antidepressant treatment works better than antidepressants alone for…
- Trial name
- NCT07691749
- Testing
- Lactobacillus Helveticus and bifidobacterium Longum
- Where
- Pakistan
- Volunteers
- 86 people
- Sponsor
- Dr Sadia yasir
Skin Barrier to Water Loss, Microbial Colonization
Oral Bifidobacterium Longum for Skin Barrier Dysfunction in Obesity
This clinical trial aims to evaluate the safety and efficacy of oral Bifidobacterium longum supplementation for treating obesity-induced skin barrier impairment in individuals aged 18-40 with BMI ≥30, compared to healthy…
- Trial name
- NCT07184905
- Testing
- Oral administration of inactive Bifidobacterium longum group, Oral Bifidobacterium longum group
- Where
- China
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Shenzhen People's Hospital
Constipation, Gastrointestinal Disorder
Effects of Probiotic Supplementation on Colonic Transit Time and Gastrointestinal Symptoms in Adults With Constipation.
To determine if Bifidobacterium lactis HN109 improves transit time and gastrointestinal symptoms in adults with constipation.
- Trial name
- NCT02189707
- Testing
- Probiotic Bifidobacterium 1x1010 cfu, Probiotic Bifidobacterium 1x109 cfu
- Where
- France
- Volunteers
- 228 people, healthy volunteers welcome
- Sponsor
- Danisco Sweeteners Oy
Infant, Newborn, Diseases, Infant Development
Probiotics and the Neurodevelopment in the Premature Infant <32 Weeks Gestational Age and <1500g
Unicentric, quasi-experimental, cohort study to evaluate the effect of combining two probiotics (Bifidobacterium bifidum NCDO 2203 and Lactobacillus acidophilus NCDO 1748) in the neurodevelopment of preterm neonates below 32…
- Trial name
- NCT05945017
- Testing
- Infloran® -Berne, Switzerland- (Bifidobacterium bifidum NCDO 2203 and Lactobacillus acidophilus NCDO 1748
- Where
- Spain
- Volunteers
- 233 people
- Sponsor
- Fundacion Clinic per a la Recerca Biomédica
Enhancement of Protective Antibody Response After Probiotic Consumption
Effect of a Mixture of Probiotics on the Antigen Specific Antibody Response in a Influenza Vaccination Model of Healthy Adults
the aim of the study is to get evidence for an enhancement of immune status in subjects after probiotics mixture consumption ( lactobacillus gasseri PA 16/8, Bifidobacterrium longum SP 07/3, Bifidobacterium bifidum MF 20/5) based…
- Trial name
- PROBIMMUNE (NCT01652066)
- Testing
- Mixture of probiotics, Mixture of probitiocs
- Where
- France
- Volunteers
- 430 people, healthy volunteers welcome
- Sponsor
- Merck Medication Familiale
Lower Abdominal Pain, Diarrhea
Efficacy and Safety of Encapsulated Bifidobacterium Longum BBH016 in Subjects With Lower Gastrointestinal Symptoms
Functional lower gastrointestinal (GI) symptoms such as abdominal pain, diarrhea, loose stools, and bloating are common in adults without identifiable organic disease and are associated with impaired quality of life and increased…
- Conditions
- Lower Abdominal Pain, Diarrhea, Irritable Bowel Syndrome
- Trial name
- NCT07484412
- Testing
- Bifidobacterium longum BBH016
- Where
- South Korea
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Seoul National University Bundang Hospital
Healthy Adult
Effect of Bifidobacterium Animalis Subsp. Lactis Bi66 Supplementation on Gut Function in Healthy Adults
The goal of this clinical trial is to learn the effect of Bifidobacterium animalis subsp. lactis Bi66 supplementation on gut function in healthy adults. The main questions it aims to answer are: 1.
- Trial name
- NCT06740500
- Testing
- Probiotic
- Where
- China
- Volunteers
- 117 people, healthy volunteers welcome
- Sponsor
- Huazhong University of Science and Technology
Healthy
Probiotics and Health-related Quality of Life in Individuals With Seasonal Allergies
In this randomized, double-blind, placebo-controlled study, participants with seasonal allergies will receive a daily probiotic or placebo for 8 weeks.
- Trial name
- JEN (NCT02349711)
- Testing
- Probiotic mixture
- Where
- United States
- Volunteers
- 224 people, healthy volunteers welcome
- Sponsor
- University of Florida
Irritable Bowel Syndrome
Efficacy of Bifidobacterium Longum 35624 on the Quality of Life of IBS Patients With Different Symptom Severity
The main objective of this observatory is to evaluate the effect of Bifidobacterium longum 35624 on the quality of life of IBS patients having different subtypes of transit pattern and different level of symptom severity
- Trial name
- NCT04662502
- Testing
- Bifidobacterium longum 35624
- Where
- France
- Volunteers
- 220 people
- Sponsor
- Biocodex
Quality of Life
B. Lactis B94 Effects of Gastrointestinal Function
The aim of this study is to determine the effect of daily consumption of Bifidobacterium animalis ssp lactis B94 (B. lactis B94) on stool frequency, gastrointestinal (GI) transit time, and gastrointestinal symptoms in adults with…
- Trial name
- NCT03277157
- Testing
- B. lactis B94
- Where
- 3 sites in United States
- Volunteers
- 28 people
- Sponsor
- University of Florida
Healthy
Probiotics (L. Gasseri, B. Bifidum, B. Longum) on Immune and Intestinal Health in Healthy Older Adults
The purpose of this study is to determine whether healthy older adults, aged 65 to 80 years, consuming a probiotic each day for three weeks will have improved immune strength and digestive health.
- Trial name
- NCT01662206
- Testing
- Probiotic
- Where
- United States
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- University of Florida
Celiac Disease, Non-celiac Gluten Sensitivity
Probiotic BL NCC 2705 and Gluten Sensitivity
The aim of the study is to confirm/prove safety of the probiotic and production of serpin in humans.
- Trial name
- NCT03775499
- Testing
- Intervention 1 : BL NCC 2705 + Maltodextrin, Intervention 1 : Maltodextrin, Intervention 2 : BL NCC 2705 + Maltodextrin
- Where
- Netherlands
- Volunteers
- 38 people
- Sponsor
- Société des Produits Nestlé (SPN)
Healthy
Stress-buffering and Sleep Disturbance-resilient Effects of a Dual Bifidobacterium Longum Combination Under Short-term Travel
This study aims to evaluate the effects of a dual Bifidobacterium longum probiotic formulation (dipro-O and dipro-X) on sleep quality, stress responses, and gut microbiota stability in healthy adults during short-term travel.
- Trial name
- NCT07511855
- Testing
- Probiotic
- Where
- Hong Kong
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Min-Tze LIONG
Bacterium; Agent
Colonization and Persistence of Bifidobacterium Longum
Healthy adults referred to as the absence of intestinal disorders, liver and kidney problems, lactose intolerance, and no use of ongoing medication for chronic diseases will be recruited.
- Trial name
- NCT01650753
- Testing
- Probiotic Powder
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Nebraska Lincoln
Non-diarrhea Functional Bowel Symptoms
Physiological Effects of Yogurt With Bb12 in Subjects With GI Symptoms Strointestinal Symptoms
Hypothesis: Daily consumption of yogurt containing probiotic bacteria (Bb12) and inulin will significantly decrease whole gut and intestinal segmental transit time The effect of accelerating intestinal transit will be associated…
- Trial name
- GM-WGTT (NCT01004484)
- Testing
- A probiotic yogurt with inulin, Acidified dairy snack
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of North Carolina, Chapel Hill
Respiratory Tract Infections
Effects of Probiotic Against Respiratory & Gastrointestinal Illnesses in Children
This project aims to study the benefits of probiotics namely Bifidobacterium lactis subsp. infantis B8762 in treatment of respiratory and gastrointestinal illnesses in children, which are found common among pre-school children in…
- Trial name
- NCT05734417
- Testing
- Probiotic
- Where
- Malaysia
- Volunteers
- 120 people
- Sponsor
- Min-Tze LIONG
Upper Respiratory Tract Infection
Probiotic Supplementation in Children Affected by Upper Respiratory Infections
The goal of this randomized non-pharmacological Intervention study is to evaluate the effects of probiotic supplements (Bifidobacterium breve M-16V, Bifidobacterium lactis HN019, Lactobacillus rhamnosus HN001) on children…
- Trial name
- PROBIOS2021 (NCT06052540)
- Testing
- Probiotic supplement
- Where
- Italy
- Volunteers
- 128 people
- Sponsor
- Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico