Clinical trials: Bifurcation Coronary Disease
Coronary Artery Disease
BiOSS Study (BiOSS LIM C Stent Registry in Bifurcated Lesions)
The BIOSS Lim C pharmacoactive Stent has characteristics of design that makes it very suitable for the treatment of bifurcational lesions .
- Trial name
- BIOSS (NCT03475563)
- Testing
- Coronary angioplasty with stent implantation
- Where
- 3 sites in Spain
- Volunteers
- 100 people
- Sponsor
- Hospital Universitari Vall d'Hebron Research Institute
Coronary Artery Disease
The Nordic Bifurcation Study III
Should we, or should we not, perform dilatation of the side branch through the main vessel stent, if there is acceptable blood flow in the side branch?
- Trial name
- BIF III (NCT00914199)
- Testing
- Percutaneous coronary intervention (PCI)
- Where
- Denmark
- Volunteers
- 477 people
- Sponsor
- Evald Hoej Christiansen
Coronary Artery Disease
Nordic Bifurcation Study. How to Use Drug Eluting Stents (DES) in Bifurcation Lesions?
How to use drug eluting stents (DES) in bifurcation lesions. A strategy of routine stenting of both main vessel and side branch versus a strategy of routine main vessel stenting and optional treatment of side branch.
- Trial name
- BIFI (NCT00376571)
- Testing
- Percutaneous coronary intervention
- Where
- Denmark
- Volunteers
- 413 people
- Sponsor
- Aarhus University Hospital Skejby
Coronary Disease
Safety and Efficacy Study of the Nile PAX Drug-Eluting Coronary Bifurcation Stent
The purpose of this trial is to assess the safety and efficacy of the Nile PAX® Drug Eluting Coronary Bifurcation Stent System for the treatment of single de novo bifurcation lesions in native coronary arteries with a main branch…
- Trial name
- BIPAX (NCT01308229)
- Testing
- Nile PAX® paclitaxel-eluting coronary stent
- Where
- 10 sites in Brazil, Bulgaria and 5 more
- Volunteers
- 102 people
- Sponsor
- MINVASYS
Coronary Artery Stenosis
COmplex BifuRcation Lesions: A Comparison Between the AXXESS Device and Culotte Stenting: An Optical Coherence Tomography (OCT) Study
The aim of this study is to compare vessel healing at 9 months using OCT imaging for two different treatment techniques for treating bifurcation lesions.
- Trial name
- COBRA (NCT00895791)
- Testing
- AXXESS Biolimus A9-eluting bifurcation stent, culotte stenting (Xience V)
- Where
- Belgium
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Coronary Artery Disease
Resting Full-cycle Ratio in Side Branch
The goal of this observational study is to evaluate diagnostic performance of resting full-cycle rate (RFR) in side branch lesion.
- Trial name
- NCT06075173
- Testing
- Resting full-cycle ration (RFR) measurments
- Where
- South Korea
- Volunteers
- 286 people
- Sponsor
- Sejong General Hospital
Coronary Artery Disease
Treatment of Bifurcated Coronary Lesions With Cypher™-Stent
This study is a prospective, randomized, single-center evaluation of the Cypher™ Sirolimus eluting coronary stent system in the treatment of de novo bifurcated coronary lesions comparing provisional modified T stenting with…
- Trial name
- NCT00288535
- Testing
- PCI of bifurcated coronary lesions using sirolimus coated stents in modified T-Stenting -Technique
- Where
- Germany
- Volunteers
- 200 people
- Sponsor
- University Heart Center Freiburg - Bad Krozingen
Coronary Arterial Disease (CAD), Restenosis, Coronary
Restrospective Analysis of MACE in Patients Treated With Drug-elluting Balloons.
Retrospective analysis of data collected in an institutional database of coronary interventions with use of drug-eluting balloons, with a prospective follow-up for major adverse cardiovascular events and living status.
- Conditions
- Coronary Arterial Disease (CAD), Restenosis, Coronary, Bifurcation Coronary Disease
- Trial name
- EASY-DEB (NCT06972225)
- Testing
- DEB
- Where
- Canada
- Volunteers
- 1,500 people
- Sponsor
- Olivier F. Bertrand
Ischemia; Heart, Stents
Immediate and Short Term Outcomes for Using Drug Coated Balloons in Treating Coronary Bifurcation Lesions
● the investigators aims to study the impact of using drug coated balloon in coronary artery bifurcation lesions on the procedural success rate \& short-term MACE.
- Trial name
- DCB (NCT05872074)
- Testing
- Coronary angiography plus percutenous coronary intervention
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Coronary Artery Disease, Bifurcation Lesion
Using 3D Imaging to Optimize Bifurcation Stenting
The primary purpose of this study is to determine whether bifurcation stenting guided by on-line three-dimensional optical frequency domain imaging (3D-OFDI) is superior to that with angiographic guidance by measuring incomplete…
- Trial name
- NCT02972489
- Testing
- 3D OFDI guidance arm, Angio guidance arm
- Where
- 2 sites in Japan, Netherlands
- Volunteers
- 106 people
- Sponsor
- Increase Co., Ltd.
Stent Restenosis, Stent Thrombosis
veRy Thin Stents for Patients With Left mAIn or bifurcatioN in Real Life: the RAIN a Multicenter Study
For permanent coronary stents, reduction of thickness of struts have become one of the most important innovation, being related to easier manipulation, reduced risk of stent thrombosis and low rate of revascularization.
- Conditions
- Stent Restenosis, Stent Thrombosis, Left Main Coronary Artery Disease, Coronary Bifurcations
- Trial name
- RAIN (NCT03544294)
- Testing
- Xience alpine, ultimaster, resolute onyx, synergy
- Where
- Italy
- Volunteers
- 2,800 people
- Sponsor
- A.O.U. Città della Salute e della Scienza
Coronary Artery Disease
Multislice CT Angiography of Coronary Bifurcations and Outcomes After Intervention
This is prospective, observational study, that will be conducted in two high-volume university interventional cardiology centers.
- Trial name
- NCT01943643
- Testing
- multislice CT angiography
- Where
- Serbia
- Volunteers
- 70 people
- Sponsor
- Clinical Hospital Center Zemun
Coronary Artery Disease, Death
Long-term Outcomes of Patients After Coronary Bifurcation Stenting
The purpose of this study is to assess the long-term clinical outcomes after stenting bifurcation coronary artery lesions, and to determine whether simple or more complex techniques are associated with a better clinical outcome.
- Conditions
- Coronary Artery Disease, Death, Myocardial Infarction
- Trial name
- NCT00325884
- Where
- United States
- Volunteers
- 160 people
- Sponsor
- VA Boston Healthcare System
Coronary Artery Disease, Ischemic Heart Disease
Comparing T-stenting And Minimal Protrusion With External Minicrush for Treatment of Complex Coronary Bifurcation
Nowadays, no studies compare the T-stenting And Minimal Protrusion (TAP) and External Minicrush techniques in treating complex coronary bifurcation, so eventually, procedural, clinical and safety differences remain unknown.
- Conditions
- Coronary Artery Disease, Ischemic Heart Disease, Chronic Coronary Syndrome, Acute Coronary Syndrome
- Trial name
- NCT06484647
- Testing
- Percutaneous Coronary Intervention
- Where
- Italy
- Volunteers
- 382 people
- Sponsor
- San Luigi Gonzaga Hospital
Bifurcation Lesion, Coronary Artery Disease
INSPIRON Sirolimus Eluting Stent Performance in Bifurcation Coronary Arteries Treated Using Provisional Technique
Evaluate the efficacy of the Inspiron Sirolimus Eluting Stent on bifurcation coronary artery lesions, in order to preserve and not compromize the side branch using the provisional stent technique.
- Trial name
- insProvisional (NCT03780192)
- Testing
- Inspiron Sirolimus Eluting Stent
- Where
- Brazil
- Volunteers
- 80 people
- Sponsor
- Scitech Produtos Medicos SA
Stable Angina
Outcome of Coronary High Angulated Bifurcation Lesions Treated With Kissing Ballooning or Sequential Ballooning Techniques
Coronary artery bifurcation lesions prone to occur with the worsening of atherosclerosis. Their structural properties make angioplasty technique to increase the difficulty of implementation, but also increased the risks of the…
- Trial name
- MV:main branch (NCT02137486)
- Where
- Taiwan
- Volunteers
- 214 people
- Sponsor
- Taipei City Hospital
Coronary Artery Disease
BiOSS LIM C vs 2nd Generation DES in Non-LM Bifurcations
Coronary bifurcations are encountered in about 15 - 20% of percutaneous coronary interventions (PCI). They are considered technically challenging and associated with worse clinical outcomes than non-bifurcation lesions.
- Trial name
- POLBOS 3 (NCT03548272)
- Testing
- Percutaneous Coronary Intervention with stent implantation
- Where
- Poland
- Volunteers
- 518 people
- Sponsor
- Central Clinical Hospital of the Ministry of Internal Affairs and Administration, Warsaw, Poland
Coronary Artery Disease
A Study of Drug Coated Balloon For Treating the Side Branch in Complex Bifurcation Lesions
Hypothesis: In patients undergoing coronary stenting for the true bifurcation lesions, main branch stenting followed by side branch dilatation with drug coated balloon is superior to the provisional-stenting strategy in terms of…
- Trial name
- STENT-FREE (NCT05222061)
- Testing
- Drug coated balloon for the side brunch, Conventional balloon for the side brunch
- Where
- Russia
- Volunteers
- 80 people
- Sponsor
- Meshalkin Research Institute of Pathology of Circulation
Coronary Artery Disease
A Study of the Cypher Sirolimus-Eluting Stent to Treat Bifurcation Lesions.
The objective of this study is to assess the feasibility and safety of the sirolimus-coated Bx VELOCITY Balloon-Expandable Stent in treating patients with true bifurcation lesions.
- Trial name
- BIFURCATION (NCT00234455)
- Testing
- drug eluting-stent, drug-eluting stent
- Where
- Italy
- Volunteers
- 86 people
- Sponsor
- Cordis US Corp.
Coronary Artery Disease (non-left Main), Coronary Bifurcation Lesion
The European Bifurcation Club Randomized Trial of Stepwise Provisional Stenting Versus Drug Coated Balloon Therapy for Non-left Main True Coronary Bifurcations
Clinical outcomes are worse in patients with coronary artery bifurcation lesions, even if commonly encountered in clinical practice.
- Trial name
- EBC DCB (NCT06822322)
- Testing
- Percutaneous Coronary Angioplasty, Stepwise Provisional Stent Strategy, Drug Coated Balloon Strategy
- Volunteers
- 750 people
- Sponsor
- Ceric Sàrl