Clinical trials: Bifurcation Lesion
Coronary Artery Disease (CAD), Coronary Bifurcation Lesion
Stenting Versus Drug Eluting Balloons Only in Treatment of Coronary Bifurcation Lesion (ROBUST Study)
The goal of this clinical trial is to learn immediate and follow up results of percutaneous treatment of coronary bifurcation lesion using drug eluting balloons (DEB) only in patients with chronic coronary syndrome (CCS).
- Conditions
- Coronary Artery Disease (CAD), Coronary Bifurcation Lesion, Coronary Stenting, Drug Eluting Balloon
- Trial name
- ROBUST (NCT07552194)
- Testing
- Balloon Angioplasty with or without drug administration
- Volunteers
- 272 people
- Sponsor
- Avtandil M. Babunashvili
Cardiovascular Diseases
Safety Study to Assess the Feasibility of Use in Humans of the TAXUS Petal Bifurcation Coronary Stent System
The purpose of this study is to determine the safety and feasibility of use in humans of the TAXUS Petal Paclitaxel-Eluting Bifurcation Coronary Stent System in the treatment of de novo lesions in native coronary arteries…
- Trial name
- NCT00497367
- Testing
- Percutaneous Coronary Intervention (PCI) TAXUS Petal
- Where
- 4 sites in France, Germany and 1 more
- Volunteers
- 28 people
- Sponsor
- Boston Scientific Corporation
Coronary Artery Disease
BiOSS Study (BiOSS LIM C Stent Registry in Bifurcated Lesions)
The BIOSS Lim C pharmacoactive Stent has characteristics of design that makes it very suitable for the treatment of bifurcational lesions .
- Trial name
- BIOSS (NCT03475563)
- Testing
- Coronary angioplasty with stent implantation
- Where
- 3 sites in Spain
- Volunteers
- 100 people
- Sponsor
- Hospital Universitari Vall d'Hebron Research Institute
Coronary Artery Disease, DCB
DCB vs. DES in Bifurcation Coronary Lesions
This is an investigator-driven prospective, multicentric, international, randomized clinical study, in an open-label randomized fashion, where patients with bifurcation coronary artery disease (Medina: 111,101,011,001) in vessels…
- Trial name
- PICCOLETO V (NCT06551662)
- Testing
- Paclitaxel drug-coated balloons, Sirolimus drug-coated balloons, New generation drug-eluting stent
- Where
- 17 sites in Italy, Poland and 2 more
- Volunteers
- 321 people
- Sponsor
- Fondazione Ricerca e Innovazione Cardiovascolare ETS
Coronary Disease
Safety and Efficacy Study of the DANUBIO Paclitaxel Eluting Balloon in Side Branches of de Novo Bifurcation Lesions (DEBSIDE)
The purpose of this study is to assess the safety and efficacy of the Danubio Paclitaxel Eluting Balloon for the treatment of side branches of de novo bifurcation lesions in native coronary arteries.
- Trial name
- DEBSIDE (NCT01485081)
- Testing
- Danubio paclitaxel-eluting balloon
- Where
- 7 sites in France
- Volunteers
- 52 people
- Sponsor
- MINVASYS
Percutaneous Coronary Intervention
The Safety and Efficacy of DIOR Balloon in Coronary Bifurcation Lesions
To evaluate the safety and effectiveness of paclitaxel-eluting coronary artery balloon dilation catheter (DIOR) in revascularization of coronary bifurcation lesions compared with paclitaxel-eluting balloon (Bingo), and to provide…
- Trial name
- BEYOND-II (NCT03820622)
- Testing
- Paclitaxel-Eluting Coronary Balloon Dilation Catheter (DIOR), Paclitaxel-Eluting Balloon (Bingo)
- Where
- 13 sites in China
- Volunteers
- 220 people
- Sponsor
- CCRF Inc., Beijing, China
Coronary Bifurcation Lesions
Treatment Of Coronary Bifurcation Lesions: Stentcovering Of The Side Branch With And Without PCI Of The Side Branch: A Retrospective Analysis Of All Consecutive Patients
This retrospective observational study included patients (pts) with percutaneous coronary intervention (PCI) of a de novo coronary bifurcation lesion in one German center between January 2008 - August 2011.
- Trial name
- NCT01538186
- Where
- Germany
- Volunteers
- 98 people
- Sponsor
- Krankenhaus Hetzelstift
Coronary Artery Disease
Coronary Bifurcation Lesions Treated With Biguard Stent System
This study is designed to test the hypothesis that the Biguard stent system will lead to fewer target lesion failure compared to regular stent system in patients with coronary bifurcation lesions at one year.
- Trial name
- BIGUARD (NCT02597283)
- Testing
- Biguard sirolimus-eluting bifurcation stent system, Sirolimus-eluting stent system
- Sponsor
- Nanjing First Hospital, Nanjing Medical University
Coronary Artery Disease
Baseline V-RESOLVE Score Guided Versus Angiography Guided Stent Implantation in Coronary Bifurcation Lesions (CIT-RESOLVE II)
The purpose of this study is to investigate whether baseline V-RESOLVE score guided intervention is associated with significant reduction of side branch occlusion rates compared to angiography guided intervention in patients with…
- Trial name
- NCT05503407
- Testing
- Baseline V-RESOLVE score-guided PCI, Angiography-guided PCI
- Where
- China
- Volunteers
- 1,104 people
- Sponsor
- China National Center for Cardiovascular Diseases
Coronary Artery Disease
Treatment of Coronary Bifurcation Lesions: Comparing Reverse T and Protrusion Versus Double-kissing and Crush Stenting
Treatment of bifurcation coronary lesions may be challenging, and the best technique to be used in these settings remains to be established.
- Trial name
- TIPTAP-I (NCT03714750)
- Testing
- DK crush, Reverse TAP
- Where
- Germany
- Volunteers
- 50 people
- Sponsor
- Tommaso Gori
Coronary Artery Disease
The Nordic-Baltic Bifurcation Study IV
How should coronary artery stenoses with significant side branch be stented? A strategy of stenting both main vessel and side branch compared to a strategy of stenting the main vessel and only stenting the side branch if…
- Trial name
- BIF IV (NCT01496638)
- Testing
- Implantation of coronary stent in bifurcation lesion
- Where
- Denmark
- Volunteers
- 450 people
- Sponsor
- Evald Hoej Christiansen
Coronary Artery Disease, Death
Long-term Outcomes of Patients After Coronary Bifurcation Stenting
The purpose of this study is to assess the long-term clinical outcomes after stenting bifurcation coronary artery lesions, and to determine whether simple or more complex techniques are associated with a better clinical outcome.
- Conditions
- Coronary Artery Disease, Death, Myocardial Infarction
- Trial name
- NCT00325884
- Where
- United States
- Volunteers
- 160 people
- Sponsor
- VA Boston Healthcare System
Angina Pectoris, Angina, Unstable
Intravascular Near Infrared Spectroscopy (NIRS) Bifurcation - Lipid Core Plaque Shift Study
This pilot study is going to examine the hypothesis that in coronary arteries, soft lesions that contain lipid cores, but are not calcified or fibrotic and are located in proximity to side branches, are associated with side…
- Conditions
- Angina Pectoris, Angina, Unstable, Atherosclerosis, Coronary Artery Disease
- Trial name
- NCT00905671
- Testing
- LipiScan Coronary Imaging Catheter
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Infraredx
Coronary Angioplasty, Bifurcation Coronary Artery Disease
Initial Study of a MOTHER-DAUGHTER SIDE-BRANCH ACCESS™ DES System (FIH Feasibility Study)
This first in human feasibility study is designed to evaluate the feasibility MD-SBA DES in subjects undergoing percutaneous coronary intervention (PCI) to treat bifurcation lesions.
- Conditions
- Coronary Angioplasty, Bifurcation Coronary Artery Disease, Ischemic Heart Disease (IHD), Percutaneous Coronary Intervention (PCI)
- Trial name
- NCT07649798
- Testing
- MD-SBA DES System
- Where
- Paraguay
- Volunteers
- 13 people
- Sponsor
- Advanced Bifurcation Systems Inc.
Coronary Heart Disease
The Study of Active Transfer of Plaque Technique for Non-Left Main Coronary Bifurcation Lesions
A Prospective Multi-center Randomized Trial Assessing the Efficacy and Safety of Active Transfer of Plaque vs. Provisional T Stenting for the Treatment of Non-Left-Main Coronary Bifurcation Lesions.
- Trial name
- NCT02768116
- Testing
- Sirolimus Drug-eluting Stent via Active Transfer of Plaque, Sirolimus Drug-eluting Stent implantation via Provisional T Stenting
- Volunteers
- 316 people
- Sponsor
- Beijing Anzhen Hospital
Coronary Artery Disease
Computed Tomography Angiography Prediction Score for Side Branch Occlusion
Lesions involving coronary bifurcations account for approximately 20% of all percutaneous coronary interventions (PCI). Revascularization within bifurcation sites remains technically challenging.
- Trial name
- CT-PRECISION (NCT03709836)
- Where
- Poland
- Volunteers
- 363 people
- Sponsor
- National Institute of Cardiology, Warsaw, Poland
CAD
Safety and Efficacy of the DEVOIR Sirolimus-Coated Coronary Balloon in the Real-world Clinical Practice
The study is a prospective, non-randomized, multicenter, post-marketing surveillance study evaluating the CE-marked DEVOIR Sirolimus-Coated Coronary Balloon in 4 subgroups regarding device approved indications: In-stent…
- Trial name
- NCT02853994
- Volunteers
- 500 people
- Sponsor
- MINVASYS
Coronary Artery Disease, Coronary Bifurcation Lesions
Progress Bifurcation Global Registry
Coronary bifurcation lesions are lesions (or blockages) that occur at or near the intersection of a major coronary artery and one of the arteries' side branches.
- Trial name
- NCT05100992
- Testing
- Percutaneous Coronary Interbention
- Where
- United States
- Volunteers
- 4,000 people
- Sponsor
- Minneapolis Heart Institute Foundation
Coronary Artery Disease
A Study of Drug Coated Balloon For Treating the Side Branch in Complex Bifurcation Lesions
Hypothesis: In patients undergoing coronary stenting for the true bifurcation lesions, main branch stenting followed by side branch dilatation with drug coated balloon is superior to the provisional-stenting strategy in terms of…
- Trial name
- STENT-FREE (NCT05222061)
- Testing
- Drug coated balloon for the side brunch, Conventional balloon for the side brunch
- Where
- Russia
- Volunteers
- 80 people
- Sponsor
- Meshalkin Research Institute of Pathology of Circulation
Coronary Artery Disease
Treatment of Bifurcated Coronary Lesions With Cypher™-Stent
This study is a prospective, randomized, single-center evaluation of the Cypher™ Sirolimus eluting coronary stent system in the treatment of de novo bifurcated coronary lesions comparing provisional modified T stenting with…
- Trial name
- NCT00288535
- Testing
- PCI of bifurcated coronary lesions using sirolimus coated stents in modified T-Stenting -Technique
- Where
- Germany
- Volunteers
- 200 people
- Sponsor
- University Heart Center Freiburg - Bad Krozingen