Clinical trials: Bilateral Cataracts
Systemic Lupus Erythematosus
WEUKBRE5716: Steroid-related Damage in Systemic Lupus Erythematosus (Hopkins)
The study is designed to assess the association between steroid exposure and five potentially steroid-related adverse events within a cohort of individuals with systemic lupus erythematosus (SLE).
- Trial name
- NCT01616472
- Testing
- Cumulative corticosteroid exposure
- Volunteers
- 1 people
- Sponsor
- GlaxoSmithKline
Cataracts
A Prospective Study Comparing Visual Outcomes and Patient Satisfaction Following Implantation of the Clareon PanOptix Versus Tecnis Odyssey IOL in Patients Undergoing Cataract Surgery.
To evaluate visual outcomes and patient satisfaction following bilateral implantation of the Clareon PanOptix versus Tecnis Odyssey IOL in patients undergoing cataract surgery
- Trial name
- NCT07768475
- Testing
- Intraocular Lens Implant
- Where
- 4 sites in United States
- Volunteers
- 266 people
- Sponsor
- Nvision Laser Eye Centers
Eye Disease, Inflammation
Analysis of Eye Tissue
The purpose of this investigation is to better understand the inflammatory process that occurs in uveitis (eye inflammation) through study of eye tissues.
- Conditions
- Eye Disease, Inflammation, Uveitis
- Trial name
- NCT00001224
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- National Eye Institute (NEI)
Cataract, Bilateral Senile Cataract
Cataract Monitored Anesthesia Care (MAC) Feasibility Pilot Study
The goal of this pilot clinical trial comparing two different sedation approaches for cataract surgery is to assess the feasibility, completeness, and distribution of data in measuring patient satisfaction, the quality of…
- Conditions
- Cataract, Bilateral Senile Cataract, Anesthesia, Patient Satisfaction
- Trial name
- CaTNAPS-1 (NCT06506669)
- Testing
- Oral sedation
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Cataract, Healthy
Dynamic Light Scattering Device (DLS) Study of Age-Related Changes in the Lens and Cataracts
This study will use a newly developed instrument called dynamic light scattering device (DLS) to examine age-related changes in the human lens and to study the causes and development of cataracts.
- Trial name
- NCT00007215
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- National Eye Institute (NEI)
Cataracts
Selection of Aspheric Diffractive Multifocal Intraocular Lens (IOLS) Based on Corneal Wavefront
Given the availability of aspheric diffractive IOLs with varying negative spherical aberration it may be feasible, by selecting the best fit IOL, to minimize aberrations and thereby maximize visual performance.
- Trial name
- NCT00999492
- Testing
- Tecnis® Multifocal (TMF)
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Mark Packer, MD, FACS
Cataract
Presbyopia-Correcting Intraocular Lenses (IOLs)
The purpose of this study is to prospectively evaluate postoperative visual and refractive parameters in a series of subjects bilaterally implanted with Presbyopia-Correcting Intraocular Lenses (IOLs).
- Trial name
- NCT00963560
- Testing
- ReSTOR +3, Crystalens HD, Crystalens AO
- Where
- United States
- Volunteers
- 132 people
- Sponsor
- Alcon Research
Cataract, Multifocal Intraocular Lens
Visual Outcomes in Patients Contralaterally Implanted With PanOptix Pro and Clareon Vivity Compared to Bilateral Implantation of PanOptix Pro
Title: Visual Outcomes in Patients Contralaterally Implanted with PanOptix Pro and Clareon Vivity Compared to Bilateral Implantation of PanOptix Pro Sponsor: Brian Shafer, MD, Shafer Vision Institute Objective: To compare visual…
- Trial name
- NCT07076277
- Testing
- Clareon PanOptix Pro and Clareon Vivity Intraocular Lens, Clareon PanOptix Pro Intraocular Lenses
- Where
- 5 sites in United States
- Volunteers
- 346 people
- Sponsor
- Brian Shafer
Cataracts
A Comparative Pilot Study Of High-Order Aberrations With Aspheric IOL Models SN60WF and ZCB00
The purpose of this study was to prospectively compare high-order aberrations between eyes implanted with the AcrySof® Natural IQ (SN60WF) intraocular lens (IOL) versus those implanted with the Tecnis ZCB00 IOL.
- Trial name
- NCT01105585
- Testing
- Tecnis 1-piece Aspheric Acrylic (ZCB00) IOL, AcrySof Natural IQ (SN60WF) IOL
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Alcon Research
Cataracts
A Real-World Study in China for the TECNIS Eyhance™ Intraocular Lens
This is a prospective and retrospective, single-center, single-arm, open-label clinical study of the TECNIS Eyhance™ IOL. The study will enroll up to 100 subjects from a single site in China.
- Trial name
- NCT05090813
- Testing
- Model ICB00
- Where
- China
- Volunteers
- 24 people
- Sponsor
- Johnson & Johnson Surgical Vision, Inc.
Cataracts
VIGADEXA Gel Compared to VIGADEXA Solution Following Cataract Surgery
The purpose of this study is to compare VIGADEXA (moxifloxacin 0.5%/dexamethasone phosphate 0.075%) ophthalmic gel to VIGADEXA (moxifloxacin 0.5%/dexamethasone phosphate 0.1%) ophthalmic solution in the prevention of…
- Trial name
- NCT01515826
- Testing
- Moxifloxacin 0.5%/Dexamethasone Phosphate 0.075% Ophthalmic Gel (VIGADEXA Gel), Moxifloxacin 0.5%/Dexamethasone Phosphate 0.1% Ophthalmic Solution (VIGADEXA Solution)
- Sponsor
- Alcon Research
Cataract Bilateral, Lens, Intraocular
Evaluation of Visual Function After Bilateral Implantation of EDOF IOLs
Since intermediate vision is becoming increasingly important in our day-to-day tasks, a new IOL was introduced (Acunex Vario) with this objective in mind.
- Conditions
- Cataract Bilateral, Lens, Intraocular, Lens Implantation, Intraocular, Pseudophakia
- Trial name
- Vario-NL (NCT05335408)
- Testing
- Acunex Vario intraocular lens, Alcon AcrySof IQ Vivity intraocular lens
- Where
- Netherlands
- Volunteers
- 32 people
- Sponsor
- Maastricht University Medical Center
Presbyopia, Refractive Errors
Premium Monovision Versus Other Types of Monovision and Bilateral Trifocal Implantation.
Primary objective of this study was to compare the efficacy of premium monovision with Restor and Panoptix, against other prevalent monovision techniques and against bilateral Panoptix implantation in a sample of patients…
- Conditions
- Presbyopia, Refractive Errors, Cataract
- Trial name
- NCT04618380
- Testing
- bUD-VA,bUN-RA, bUI-RA, bUI-CPS, bUN-CPS, contrast sensitivity
- Where
- Greece
- Volunteers
- 120 people
- Sponsor
- Democritus University of Thrace
Patients With Systemic Inflammatory Diseases Receiving for the First Time a Protracted General Corticostroid Therapy
Impact of Systemic Corticosteroid Therapy on Lens Transparency and Quantification of Lens Autofluorescence.
Corticosteroid therapy is usually regarded as a risk factor for the development of posterior subcapsular cataracts but prospective studies on this topic and accurate assessment of this potential adverse effect are lacking.
- Trial name
- NCT00337623
- Testing
- Prednisolone
- Where
- France
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- University Hospital, Clermont-Ferrand
Cataract, Presbyopia
Comparison of Two Aspheric Intraocular Lenses for Micro-monovision
In an aging population, cataract and presbyopia become increasingly common. A cataract develops when the natural crystalline lens inside a person's eye, becomes cloudy over time, causing reduction of vision.
- Conditions
- Cataract, Presbyopia, Pseudophakia
- Trial name
- NCT05531110
- Testing
- Cataract surgery with insertion of Eyhance ICB00, Cataract surgery with insertion of Alcon SN60WF
- Where
- United Kingdom
- Volunteers
- 140 people
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
Cataracts
Multifocals and Accommodating/Bilateral Implantation of Different Multifocal Intraocular Lens (IOLs)
The purpose of this study is to evaluate vision at different distances (far (13 ft), intermediate (2.0 ft) and near (13 to 15 in)) with and without the patient's glasses (if the patient wears them), range of vision (the…
- Trial name
- NCT00934960
- Where
- United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Congenital Cataract
Secondary Intraocular Lens Implantation in Pediatric Patients
This prospective, non-randomized controlled study aiming at comparing the prognosis of minimal invasive lens surgery and traditional cataract surgery for treating congenital cataracts after the patient receives secondary…
- Trial name
- NCT03240796
- Testing
- minimal invasive surgery and secondary IOL implantation, traditional cataract surgery and secondary IOL implantation
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Sun Yat-sen University
Cataract Bilateral, Presbyopia
Tecnis ZLB00 & Symfony Intraocular Lens Combination Outcomes
Current visual outcomes expectations of cataract patients are similar to those of refractive surgery patients. Their desire is to be spectacle independent for far, intermediate and near vision activities.
- Trial name
- NCT03771274
- Testing
- Tecnis ZLB00 & Symfony IOL
- Where
- United States
- Volunteers
- 39 people
- Sponsor
- Carolina Eyecare Physicians, LLC
Cataract
Cataract Surgery to Obtain Human Lens Material for the Study of Nuclear Cataracts
Cataract, in which the lens of the eye is opacified, is the major cause of blindness. This study will examine protein material of the lens called crystallins to try to determine what causes nuclear cataracts, a type of cataract…
- Trial name
- NCT00001613
- Where
- United States
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- National Eye Institute (NEI)
Cataracts
Cataract Surgery in Indian Patients With or Without LenSx® Laser
The purpose of this study is to record and analyze the profile and outcome of cataract patients receiving phacoemulsification (phaco) and artificial intraocular lens (IOL) implantation with or without femtosecond laser-assisted…
- Trial name
- NCT02605408
- Testing
- LenSx® laser system, Phacoemulsification
- Sponsor
- Alcon Research