Clinical trials: Bilateral Cataracts
Cataract
Antioxidants for Prevention of Cataracts Follow-up Study
Aravind Eye Hospital and the University of California, San Francisco (UCSF) Proctor Foundation collaborated on the Antioxidants for the Prevention of Cataract Study from 1997-2002.
- Trial name
- NCT01664819
- Testing
- Antioxidant
- Where
- India
- Volunteers
- 576 people
- Sponsor
- University of California, San Francisco
Bilateral Cataract
Immediate Simultaneous Bilateral Cataract Surgery
To evaluate the safety and efficacy of treating visually significant bilateral cataract with the newer technique of Immediate Simultaneous Bilateral Cataract Surgery (ISBCS) versus the conventional technique of Delayed Sequential…
- Trial name
- ISBCS (NCT01841957)
- Testing
- ISBCS, DSBCS
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Sloan W. Rush, MD
Cataract
A Intra-patient Comparison of Closed Loop and Plate Haptic Toric Intraocular Lenses
During cataract surgery an artificial lens is implanted in the eye. These artificial lenses are called intraocular lenses (IOLs) and there are many different types of IOL designs.
- Trial name
- NCT02264457
- Testing
- T-flex Aspheric Toric IOL, AT TORBI toric IOL
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- University of Plymouth
Cataract
A Clinical Assessment of the Full Range of Functional Vision With Three Tecnis Multifocal IOL 1-Piece Models in Bilateral Cataract Extraction
The objective of this study is to evaluate the uncorrected binocular distance, intermediate, and near visual acuities, and assess patient's spectacle independence and satisfaction in individuals undergoing bilateral cataract…
- Trial name
- NCT02863159
- Testing
- Tecnis Multifocal 1-Piece IOL
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Dell Laser Consultants
Cataracts
DisCoVisc Comparative Evaluation
A comparison of the ability of DisCoVisc to that of other Opthalmic Viscosurgical Devices (OVDs) (DuoVisc®, BioVisc®, Healon5®, or Amvisc PLUS) regarding endothelial protection and anterior chamber space maintenance during…
- Trial name
- NCT00732225
- Testing
- DisCoVisc, DuoVisc, BioVisc
- Where
- United States
- Volunteers
- 173 people
- Sponsor
- Alcon Research
Hyperalgesia, Cataract Bilateral Nos
Gabapentin Pretreatment for Staged Bilateral Cataract Operations
To evaluate the effect of oral gabapentin premedication on hyperalgesia in elderly patients undergoing staged bilateral cataract operations under monitored anesthesia care
- Trial name
- NCT03826615
- Testing
- Gabapentin
- Where
- South Korea
- Volunteers
- 64 people
- Sponsor
- Seoul National University Hospital
Cataracts
Accuracy of Holladay 2 Formula in the Absence of Lens Thickness
Hypothesis: Holladay 2 formula is still accurate even used without lens thickness data.
- Trial name
- NCT01846078
- Testing
- optical biometric measurement (IOLMaster)
- Where
- Thailand
- Volunteers
- 143 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Cataracts
A Comparison of Peak Aqueous Penetration of Acuvail (Ketorolac 0.45%), Xibrom (Bromfenac 0.09%), and Nevanac (Nepafenac 0.1%)in Patients Undergoing Phacoemulsification
Approximately 126 subjects scheduled to undergo cataract surgery by phacoemulsification, will be randomized in an even allocation (1:1:1) to either Acuvail, Xibrom, or Nevanac.
- Trial name
- NCT01001806
- Testing
- Ketorolac Tromethamine 0.45%, bromfenac 0.09%, nepafenac 0.1%
- Where
- United States
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Frank A. Bucci, Jr., M.D.
Cataract, Lens Opacities
Comparison of Clinical Outcomes on Trifocal IOLs FineVision POD F GF and FineVision POD F in Asian Eyes
Prospective, randomised, controlled, single-surgeon, single-center clinical study to compare the clinical outcomes of two trifocal IOLs with different material (hydrophobic and hydrophilic) from the same manufacturer.
- Conditions
- Cataract, Lens Opacities, Presbyopia
- Trial name
- PHY1706 (NCT03306355)
- Testing
- IOL implantation experimental, IOL implantation active comparator
- Where
- Philippines
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Beaver-Visitec International, Inc.
Cataracts
Safety and Effectiveness of the Calhoun Vision Light Adjustable Intraocular Lens (LAL)
The primary objective of this study is to evaluate, for the visual correction of aphakia, the safety and effectiveness of the Calhoun Vision Light Adjustable intraocular lens (LAL) and Light Delivery Device (LDD) in treating…
- Trial name
- NCT00845520
- Testing
- Lens implantation +1.00 D postop target, Lens implantation -1.00 D postop target, Lens implantation 0.00 D postop target
- Where
- 6 sites in United States, Mexico
- Volunteers
- 74 people
- Sponsor
- Calhoun Vision, Inc.
Cataracts
Modified Intraocular Lens to Reduce Eye Inflammation After Cataract Surgery in Uveitis Patients
This study will test the effectiveness of an intraocular lens treated with heparin in reducing or preventing inflammation after cataract surgery in patients with uveitis.
- Trial name
- NCT00001311
- Testing
- heparin-surface modified intraocular lens
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- National Eye Institute (NEI)
Age Related Cataracts, Cystoid Macular Edema
Evaluation of Central Macular Thickness in Femtosecond Laser-assisted Cataract Surgery
The investigational device is an approved femtosecond laser (FSL) device with an integrated imaging system to perform certain steps of the cataract procedure.
- Trial name
- FLAME (NCT03465124)
- Testing
- Femtosecond Laser, Manual Cataract Surgery
- Where
- Austria
- Volunteers
- 60 people
- Sponsor
- Medical University of Vienna
Microphthalmos With Congenital Cataracts
Long-term Postoperative Outcomes After Bilateral Congenital Cataract Surgery in Eyes With Microphthalmos
Cataract surgery in infantile eyes, which are microphthalmic, can be even more demanding. In addition, the frequent presence of other ocular and systemic anomalies such as nystagmus, glaucoma, amblyopia, and higher rate of…
- Trial name
- NCT01818037
- Testing
- Cataract surgery
- Where
- India
- Volunteers
- 36 people
- Sponsor
- Iladevi Cataract and IOL Research Center
Inclusion Body Myositis, Sporadic, Inclusion Body Myopathy, Autosomal-recessive
Natural History in CCFDN and IBM Syndromes
So far, only limited data is available regarding the natural course in Congenital Cataract Facial Dysmorphism Neuropathy Syndrome (CCFDN) and sporadic and hereditary inclusion body myopathies (IBM).
- Conditions
- Inclusion Body Myositis, Sporadic, Inclusion Body Myopathy, Autosomal-recessive, Inclusion Body Myopathy, Autosomal-dominant, Congenital Cataracts, Facial Dysmorphism, And Neuropathy
- Trial name
- NCT01902940
- Testing
- Natural History
- Where
- Germany
- Volunteers
- 350 people
- Sponsor
- Ludwig-Maximilians - University of Munich
Age Related Cataracts, Pseudoexfoliation Syndrome
Outcome of Two Surgical Methods for IOLImplantation in Eyes With Pseudoexfoliation Syndrome
The aim of this study is to compare the surgical outcomes of the two IOL implantation methods for eyes with cataract and PEX in a single-center and with highly experienced surgeons.
- Trial name
- NCT06053554
- Testing
- Phakoemulsification, Ziemer Z8 Femtolaser, Kowa Avansee Preset
- Where
- Austria
- Volunteers
- 120 people
- Sponsor
- Medical University of Vienna
Cataract
Visual Performance of Bilateral AcrySof ReSTOR Aspheric +4
Determine the clinical visual outcomes following bilateral implantation of the AcrySof ReSTOR Aspheric Intraocular Lens (IOL) and to demonstrate what percentage of the subjects obtain spectacle freedom.
- Trial name
- NCT01215045
- Testing
- AcrySof ReSTOR Aspheric +4
- Where
- United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Alcon Research
Cataract
Evaluation of Quality of Vision and Visual Outcomes With Bilateral Implantation of the Clareon PanOptix Intraocular Lens
To evaluate visual outcomes and quality of vision following bilateral implantation of the Clareon PanOptix intraocular lens (IOL) targeted for emmetropia.
- Trial name
- NCT05518539
- Testing
- The Clareon™ PanOptix™ Trifocal (toric and non-toric models)
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Newsom Eye & Laser Center
Cataract
Comparison of Artificial Intelligent Clinic and Normal Clinic
In this study, the investigators provide participants≤14 years old the artificial intelligent clinic or normal clinic in the purpose of seeking out a better way to make a definite diagnosis with high efficiency and accuracy, and…
- Trial name
- NCT03240848
- Testing
- artificial intelligent clinic, normal clinic, experts diagnose
- Where
- China
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- Sun Yat-sen University
Cataract, Macular Degeneration Advanced
Cataract Surgery on Advanced Age Related Macular Degeneration Patients
The degree at which cataract surgery improves visual function in patients with advanced age-related macular degeneration (Advanced AMD) has been an on-going topic of discussion.
- Trial name
- NCT04045704
- Testing
- Cataract Surgery
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of British Columbia
Glistenings
Evaluation of Glistenings in Intraocular Lenses Implanted in Normal Patients Following Routine Cataract Extraction.
Evaluation of glistenings in intraocular lenses implanted in normal patients following routine cataract surgery. The lenses used will be Model X-60 made by the AVS company Vs AcrySof MA50BM made by the Alcon company.
- Trial name
- AVS Vs MA50BM (NCT01131481)
- Testing
- Intraocular lens
- Where
- United States
- Sponsor
- Fry Eye Associates and Fry Eye Surgery Center