Clinical trials: Bilateral Total Knee Arthroplasty
Pain, Postoperative, Total Knee Replacement
Postoperative Pain and Blood Loss of Non-use Compared to Partial-use of a Tourniquet in Bilateral Total Knee Replacement
Postoperative pain and blood loss of non-use compared to partial-use of a tourniquet in bilateral total knee replacement: A Randomized- Control Trial This study aimed to compare the effects of non-use (NTU) and partial-use…
- Conditions
- Pain, Postoperative, Total Knee Replacement, Tourniquet
- Trial name
- TKA (NCT06815445)
- Testing
- None tourniquet
- Where
- Thailand
- Volunteers
- 20 people
- Sponsor
- Queen Savang Vadhana Memorial Hospital, Thailand
Osteoarthritis
Evaluation of Diprospan Injection to the Knee on Rehabilitation of Patients After TKR of the Contralateral Knee
This study is performed to assess the influence of intraarticular injection of 2ml Diprospan (wich contains 4mg Betamethasone sodium phosphate and 10mg Betamethasone dipropionate) into osteoarthritic knee in patients who undergo…
- Trial name
- NCT00542139
- Testing
- Betamethasone, Bupivocaine
- Where
- Israel
- Volunteers
- 50 people
- Sponsor
- Hadassah Medical Organization
Total Knee Arthroplasty, Knee Pain
Optimizing Local Anesthetic Concentration for Continuous Femoral Nerve Blocks
This is a randomized, observer-masked, controlled study. Subjects will be patients undergoing bilateral total knee arthroplasty (TKA).
- Trial name
- NCT00923598
- Testing
- 0.1% and 0.4% perineural ropivicaine
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- University of California, San Diego
Gonarthrosis; Primary, Gonarthrosis
Comparison of Multiradius and Singleradius Total Knee Arthroplasty
The Investigators would like to compare multiradius and single-radius total knee arthroplasty using with association between sagittal patellar offset and anterior knee pain in subjects having undergone bilateral total knee…
- Conditions
- Gonarthrosis; Primary, Gonarthrosis, Gonarthrosis; Primary, Bilateral, Knee Osteoarthritis
- Trial name
- NCT04364971
- Testing
- singleradius and multiradius total knee arthroplasty
- Where
- Turkey (Türkiye)
- Volunteers
- 494 people
- Sponsor
- Bezmialem Vakif University
Total Knee Replacement
Comparison of Surgical Site Infection After Skin Closure by Prolene or Staples in Bilateral Knee Arthroplasty Patients
Knee arthroplasty also known as the total knee replacement is an orthopedic surgical procedure done to resurface the knee that has been severely damaged by arthritis.
- Trial name
- NCT04492852
- Testing
- Polypropylene (PROLENE) sutures, Staple Sutures
- Volunteers
- 82 people
- Sponsor
- Indus Hospital and Health Network
Bilateral Total Knee Arthroplasty
Efficacy of Pain Control in Different Bupivacaine Dose in Periarticular Injection in Bilateral Total Knee Arthroplasty
To study efficacy of postoperative pain control of different concentrations of bupivacaine for periarticular infiltration, part of multimodal analgesia, in bilateral total knee arthroplasty.
- Trial name
- NCT03249662
- Testing
- bupivacaine 200 mg, bupivacaine 100 mg
- Where
- Thailand
- Volunteers
- 60 people
- Sponsor
- Mahidol University
Arthroplasty Complications, Arthroplasty, Replacement, Knee
Kinesiotape for Edema After Bilateral Total Knee Arthroplasty
The purpose of this study is to determine if kinesiotaping for edema management will decrease post-operative edema in patients with bilateral total knee arthroplasty.
- Trial name
- NCT05013879
- Testing
- Kinesio(R)Tape for edema control
- Where
- United States
- Volunteers
- 65 people
- Sponsor
- Montefiore Medical Center
Knee Arthroplasty, Total, Peripheral Nerve Block
Postoperative Analgesia in Bilateral Knee Arthroplasties
To observationally compare the analgesic efficacy of LIA and S-FICB techniques and to record the pain scores of patients who underwent bilateral knee operations in the postoperative period.
- Conditions
- Knee Arthroplasty, Total, Peripheral Nerve Block, Pain, Postoperative
- Trial name
- NCT06357013
- Testing
- Bilateral Suprainguinal fascia iliaca compartment block, Local infiltration analgesia
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Kocaeli City Hospital
Total Knee Anthroplasty, Osteoarthritis(Primary)
COntralateral CorticoSTeroid Injection in Total Knee Arthroplasty
Through a triple-blinded randomized control trial, the primary purpose of this pilot study is to assess the efficacy of administering peri-operative contralateral corticosteroid injection in patients undergoing TKA.
- Conditions
- Total Knee Anthroplasty, Osteoarthritis(Primary), Osteoarthritis (OA) of the Knee, Bilateral Knee Osteoarthritis
- Trial name
- COSTI (NCT06809998)
- Testing
- Corticosteroid Injection - 80mg methylprednisolone (total volume 2ml) with 6 mL of 1% Bupivacaine without epinephrine (Total Volume 8 mL)., Band-Aid
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- Unity Health Toronto
Knee Osteoarthritis, Total Knee Arthroplasty
Adductor Canal Block Methods in Bilateral Total Knee Arthroplasty
This study aims to compare the analgesic efficacy of surgeon-performed intraoperative adductor canal block (ACB) and ultrasound-guided anesthesiologist-performed ACB in patients undergoing bilateral total knee arthroplasty (TKA).
- Conditions
- Knee Osteoarthritis, Total Knee Arthroplasty, Postoperative Pain, Peripheral Nerve Block
- Trial name
- NCT07506629
- Testing
- Surgeon-Performed Adductor Canal Block, Ultrasound-Guided Adductor Canal Block
- Volunteers
- 48 people
- Sponsor
- Yonsei University
Arthritis Knee, Anesthesia
Prediction Model of Acute Postoperative Pain in Bilateral Total Knee Replacement Arthroplasty Patient
This study aims to predict risk factors of acute postoperative pain of the patients undergoing Total Knee Replacement Arthroplasty(TKRA).
- Conditions
- Arthritis Knee, Anesthesia, Arthropathy of Knee
- Trial name
- NCT03765723
- Where
- South Korea
- Volunteers
- 100 people
- Sponsor
- Seoul National University Hospital
Osteoarthritis, Knee, Postoperative Edema
Effect of Tergase Injection on Reducing Edema After Bilateral Total Knee Arthroplasty
This clinical trial is conducted to compare and evaluate the efficacy and safety of Tergase injection (4,500 IU) in reducing postoperative edema between treated and untreated knees in patients undergoing bilateral total knee…
- Conditions
- Osteoarthritis, Knee, Postoperative Edema, Bilateral Total Knee Arthroplasty
- Trial name
- ALT-TKA (NCT07705165)
- Testing
- Berahyaluronidase alfa
- Volunteers
- 30 people
- Sponsor
- Man Soo Kim
Pain, Postoperative
Local Infiltration Analgesia in Bilateral Knee Arthroplasty - Efficacy of Subcutaneous Wound Infiltration With Local Anesthetic
Local infiltration analgesia is effective in total knee arthroplasty for postoperative pain management, but the efficacy of subcutaneous wound infiltration has not been evaluated.
- Trial name
- NCT00927225
- Testing
- ropivacaine 0.2%, 50 mL, normal saline
- Where
- Denmark
- Volunteers
- 16 people
- Sponsor
- Hvidovre University Hospital
Osteoarthritis
Comparison of Function and Fit of Standard and Gender-Specific CR High-Flex Total Knee Prostheses
The purpose of this prospective, randomized study was to compare functional outcome, radiographic results, range of motion, patients satisfaction, and fit of the femoral component in patients receiving either a standard posterior…
- Trial name
- CR (NCT00916968)
- Testing
- Standard CR-Flex total knee, Gender specific CR-Flex
- Where
- South Korea
- Volunteers
- 146 people
- Sponsor
- Ewha Womans University
Knee Osteoarthritis
PSI for Bilateral Simultaneous TKA in Sever Varus
the Purpose of this study was to evaluate the short term outcome of patient specific instrument (PSI) in cases of bilateral simultaneous total knee arthroplasty (TKA) for knee osteoarthritis with sever varus
- Trial name
- NCT01998321
- Testing
- Patient specific instrument, conventional technique for TKA
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- October 6 University
Anemia, Transfusion
Perioperative Iron With Erythropoietin in Bilateral Total Knee Replacement Arthroplasty (TKRA)
The object of this study is to evaluate whether low dose intravenous iron and erythropoietin (Epo) can decrease transfusion requirement after the bilateral TKRA.
- Trial name
- SNUBH (NCT01012063)
- Testing
- iron sucrose, erythropoietin-β, normal saline
- Where
- South Korea
- Volunteers
- 54 people
- Sponsor
- Seoul National University Bundang Hospital
Osteoarthritis, Total Knee Arthroplasty
Cemented vs Cementless in Bilateral TKA
To compare the functional outcomes between cemented and cementless TKA in bilateral knee replacement patient.
- Trial name
- NCT04496102
- Testing
- Triathlon
- Where
- Thailand
- Volunteers
- 50 people
- Sponsor
- Thammasat University
Knee Osteoarthritis
Population Pharmacokinetics of Ropivacaine
The aim of this study was to investigate the pharmacokinetics of free and total ropivacaine after unilateral and bilateral TKA. A population model was successfully built and peak free ropivacaine concentration stayed below…
- Trial name
- NCT04702282
- Testing
- ropivacain concentration measurements
- Volunteers
- 28 people
- Sponsor
- Hvidovre University Hospital
Osteoarthritis of Knee, Central Sensitization
Duloxetine As an Analgesic in Patients Without Central Sensitivity After Same Sitting Bilateral Total Knee Arthroplasty
Analgesic effect of 20mg Duloxetine was evaluated at regular short term intervals in patients without central sensitivity and undergoing bilateral single sitting total knee arthroplasty for tricompartmental osteoarthritis using…
- Conditions
- Osteoarthritis of Knee, Central Sensitization, Central Sensitisation
- Trial name
- NCT06837012
- Testing
- Duloxetine - low dose
- Where
- India
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- Orthopaedic Arthroscopy Knee and Shoulder Clinic
Knee Osteoarthritis
Pain Compared Between the First and the Second Surgery in Staged BTKA
postoperative pain and analgesic consumption between the first and the second surgery would be compared in patients undergoing staged bilateral total knee arthroplasty (BTKA).
- Trial name
- NCT01457313
- Where
- South Korea
- Volunteers
- 34 people
- Sponsor
- Seoul National University Bundang Hospital