Clinical trials: Bile Duct Injury
Primary Biliary Cirrhosis
Effectiveness of S-adenosyl-L-methionine in Patients With Primary Biliary Cirrhosis
Primary biliary cirrhosis (PBC) is a chronic cholestatic liver disorder which may lead to several symptoms such as intractable pruritus or chronic fatigue, significantly impairing patients quality of life.
- Trial name
- NCT02557360
- Testing
- S-adenosyl-L-methionine
- Where
- 2 sites in Poland
- Volunteers
- 24 people
- Sponsor
- Pomeranian Medical University Szczecin
Cholestasis
Omegaven® as Parenteral Nutrition
The purpose of this study is to determine if a fat emulsion comprised of omega-3 fatty acids, Omegaven, would be beneficial in the management of steatotic liver injury in parenteral nutrition (PN) by its inhibition of de novo…
- Trial name
- NCT02334293
- Testing
- Omegaven
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Carle Foundation Hospital
Virtual Reality, Gallbladder
Virtual Reality Training for Laparoscopic Cholecystectomy
Cholecystectomy is one the most frequent laparoscopic procedures worldwide. It is a safe and effective operation but intraoperative bile duct injury remains a relevant complication with serious consequences for the patient.
- Conditions
- Virtual Reality, Gallbladder, Bile Duct Injury, Medical Education
- Trial name
- NCT05169073
- Testing
- Virtual Reality training, Conventional training
- Where
- Switzerland
- Volunteers
- 20 people
- Sponsor
- University Hospital, Basel, Switzerland
Bile Duct Obstruction, Extrahepatic
Reconstruction of the Bile Duct With the Round Ligament
The investigators developed a new surgical technique in order to reconstruct the bile duct with the round ligament
- Trial name
- NCT03030573
- Testing
- Reconstruction of the bile duct with the round ligament
- Where
- France
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Beaujon Hospital
Cholestasis, Cholestasis of Parenteral Nutrition
Compassionate Use of an Intravenous Fish Oil Emulsion in the Treatment of Liver Injury in Infants
To provide a mechanism for critically ill infants with parenteral nutrition (PN) associated cholestasis to receive Omegaven for compassionate use situations for which there are no satisfactory alternative treatments.
- Trial name
- NCT00738101
- Testing
- Omegaven
- Where
- 2 sites in United States
- Volunteers
- 293 people
- Sponsor
- Baylor College of Medicine
Fluorenscent Image Guided Surgery, Indocyanide Green
Intra-gallbladder or Systemic Indocyanide Green Injection Facilitate Cholecystectomy.
The investigators will collect the pre-operative medical history and arrange physical examination, life quality evaluation, blood and biochemical test.
- Trial name
- NCT03024892
- Testing
- ICG GB, ICG IV, LC conventional
- Where
- Taiwan
- Volunteers
- 600 people
- Sponsor
- Chang Gung Memorial Hospital
Cholestasis, Total Parenteral Nutrition-induced Cholestasis
Intravenous Fish Oils in the Treatment of Parenteral Nutrition Liver Injury
The purpose of this study is to provide intravenous omega-3 fatty acids and monitor tolerance in subjects with prolonged parenteral nutrition dependence and parenteral nutrition-associated cholestasis through expanded access.
- Trial name
- NCT02780193
- Testing
- Omegaven
- Where
- United States
- Sponsor
- Rush University Medical Center
Liver Disease
Compassionate Use of IV Fish Oil for Parenteral Nutrition (PN) Liver Injury
To establish a process by which critically ill infants with parenteral nutrition-associated liver disease can receive a fish oil-based intravenous lipid emulsion (Omegaven®) for compassionate use when no satisfactory alternative…
- Trial name
- Omegaven (NCT01425567)
- Testing
- Intravenous Lipid Emulsion Comprised of Fish Oil
- Where
- United States
- Sponsor
- The University of Texas Health Science Center at San Antonio
Common Bile Duct Injury
Post-cholecystectomy Major Bile Duct Injury
Bile duct injury (BDI) is one of the devastating recognized complications of cholecystectomy which does not respect the seniority or experience of the surgeon.
- Trial name
- NCT05436626
- Testing
- Early BDI reconstruction without abdominal sepsis control, Early BDI reconstruction with abdominal sepsis control, Delayed reconstruction
- Volunteers
- 277 people
- Sponsor
- South Valley University
Primary Sclerosing Cholangitis
Primary Sclerosing Cholangitis With Oral Vancomycin by the Study of Its Antimicrobial and Immunomodulating Effects
Determine the benefit of oral vancomycin therapy for Primary Sclerosing Cholangitis.
- Trial name
- PSC (NCT01802073)
- Testing
- Oral Vancomycin
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Stanford University
Bile Duct Injury
Laparoscopic Versus Open Surgical Management of Post Cholecystectomy Bile Duct Injury
Comparison between laparoscopic and open surgical management of post cholecystectomy bile duct injury.
- Trial name
- NCT05243225
- Testing
- Laparoscopic versus open surgical management of post cholecystectomy bile duct injury
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Assiut University
Therapeutic Endoscopic Ultrasound, Advanced Endoscopy
Therapeutic Endoscopic Ultrasound for Gastrointestinal Disorders: A Multicenter Registry Study
The purpose of this retrospective chart-review registry study is to evaluate the safety profile, efficacy profile and cost-effectiveness of the various therapeutic endoscopic ultrasound (EUS) procedures (for benign and malignant…
- Conditions
- Therapeutic Endoscopic Ultrasound, Advanced Endoscopy, Therapeutic Endoscopy, Interventional Endoscopy
- Trial name
- TEUS Registry (NCT05051358)
- Testing
- Therapeutic Endoscopic Ultrasound
- Where
- United States
- Volunteers
- 5,000 people
- Sponsor
- Advanced Endoscopy Research, Robert Wood Johnson Medical School Rutgers University
Cholecystectomy, Laparoscopic
Smart Intraoperative Reminder to Implement Safety Principles in Laparoscopic Cholecystectomy
The Critical View of Safety (CVS) is universally recommended to prevent bile duct injuries in laparoscopic cholecystectomy. However, CVS is underutilized and bile duct injuries are not decreasing.
- Trial name
- CVS-Notifier (NCT06895200)
- Testing
- CVS-Notifier SaMD
- Where
- France
- Volunteers
- 40 people
- Sponsor
- IHU Strasbourg
Surgery, Biliary Disease
Bile Duct Injury Digestif
Data accumulated from medical record collected from January 2008 until December 2018
- Conditions
- Surgery, Biliary Disease, Bile Duct Injury, Sepsis
- Trial name
- NCT04582240
- Testing
- no intervention
- Volunteers
- 24 people
- Sponsor
- Dr Cipto Mangunkusumo General Hospital
Bile Duct Injury
FLuorescence Cholangiography Using Methylene Blue
Open label prospective, non-randomised proof of principle study assessing the use of methylene blue fluorescence cholangiography.
- Trial name
- FLoCaMB (NCT03386201)
- Testing
- Intravenous Methylene blue
- Where
- United Kingdom
- Volunteers
- 40 people
- Sponsor
- University of Oxford
Cholangiocarcinoma, Klatskin Tumor
Endoscopic Radiofrequency Ablation for Unresectable Cholangiocarcinoma
The goal of this clinical trial is to learn about radiofrequency ablation in patients with unresectable bile duct cancer who receive systemic chemotherapy and bile duct stenting.
- Conditions
- Cholangiocarcinoma, Klatskin Tumor, Bile Duct Cancer, Liver Cancer
- Trial name
- ACTICCA-2 (NCT06175845)
- Testing
- Intraductal biliary radiofrequency ablation
- Where
- 9 sites in Germany
- Volunteers
- 130 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Bile Duct Injury
Factors Influencing Occurrence Of Hilar Biliary Stricture In Case of Bile Duct Injury
The bile duct injury is a complication that occurs mainly after the cholecystectomy. Bile duct stricture is one of complications of this unwitting iatrogenic injury, the outcomes of surgery in this case are worse when the level…
- Trial name
- NCT04286763
- Testing
- Biliary RMI and CT scan.
- Where
- Algeria
- Volunteers
- 53 people
- Sponsor
- University of Oran 1
Biliary Strictur After Hepatojejunostomy (HJ), Morbidity and Mortality After and Around HJ
Long Time Follow up After HJ Following Iatrogenic Bile Duct Injuries
Introduction: Bile duct injury (BDI) after cholecystectomy remains a serious complication with major implications for patient outcome. For most major BDIs, the recommended method of repair is a hepaticojejunostomy (HJ).
- Trial name
- NCT01447030
- Volunteers
- 139 people
- Sponsor
- Odense University Hospital
Total Parenteral Nutrition-induced Cholestasis
Intravenous Fat Emulsion Comprised of Fish Oil in the Treatment of Parenteral Nutrition Induced Liver Injury in Infants
To provide a mechanism for critically ill infants with parenteral nutrition (PN) associated cholestasis to receive Omegaven for compassionate use situations for which there are no satisfactory alternative treatments.
- Trial name
- NCT02534077
- Testing
- Omegaven
- Where
- United States
- Sponsor
- Pediatrix
Bile Duct Obstruction
Flushing of Internalized Percutaneous Transhepatic Biliary Drainage Catheters
Percutaneous transhepatic biliary drainage (PTBD) is a drainage method for biliary obstruction. Patients with a PTBD catheter often need multiple re-interventions because of symptoms of catheter obstruction such as pain…
- Trial name
- FLUSH (NCT04915703)
- Testing
- Flushing of PTBD catheter
- Where
- Netherlands
- Volunteers
- 38 people
- Sponsor
- Erasmus Medical Center