Clinical trials: Bile Reflux
Artificial Intelligence, Tongue
Connection Between Tongue Signs and Bile Reflux Analysed With Artificial Intelligence
By introducing artificial intelligence into Chinese medicine tongue diagnosis, we collated and collected tongue images, anxiety and depression scales and gastroscopy reports, mined and analysed the correlation between tongue…
- Conditions
- Artificial Intelligence, Tongue, Bile Reflux
- Trial name
- NCT05369572
- Where
- China
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- Shandong University
Acid Reflux Esophagitis, Non-acid Reflux Esophagitis
Resolving Bile Reflux by Lanreotide in Patients With Roux-en-Y Gastrojejunostomy
Somatostatine induces a dose-dependent reduction of postprandial plasma cholecystokinin (CCK) secretion with a concomitant inhibition of postprandial gallbladder contraction, abolishing almost completely bile salts output from…
- Trial name
- NCT02054637
- Testing
- Lanreotide
- Where
- Belgium
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Universitair Ziekenhuis Brussel
Bile Reflux, Gastric Cancer
Associations Among Serum and Gastric Juice Bile Acid Profile, Bile Acid-microbiota Cross-talk in Stomach and the Development of Gastric Cancer
To explore the associations among bile acid profile, bile acid-microbiota cross-talk and the development of gastric cancer, so as to better prevent the occurrence and development of gastric cancer
- Conditions
- Bile Reflux, Gastric Cancer, Precancerous Lesion
- Trial name
- NCT04660058
- Where
- China
- Volunteers
- 73 people
- Sponsor
- Xijing Hospital of Digestive Diseases
Gastroesophageal Reflux Disease
Clinical Studies on Bile Acids in Barrett's Esophagus
This study has two major goals: 1. To determine the effects of bile salts on causing DNA injury and activating signaling pathways that promote growth in cells from the esophagus of patients who have gastroesophageal reflux…
- Trial name
- NCT00858858
- Testing
- Ursodeoxycholic Acid
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- US Department of Veterans Affairs
Pulmonary Aspiration of Gastric Contents
Prophylaxis for Aspiration of Gastric Contents.
Effect of orally administered two equal and consecutive doses of proton pump inhibitors, omeprazole, lansoprazole, esomeprazole , rabeprazole and pantoprazole and Histamine 2 receptor antagonists cimetidine…
- Trial name
- NCT02703896
- Testing
- Drug either PPIS or H2RA and prokinetics, orogastric intubation
- Volunteers
- 1,920 people, healthy volunteers welcome
- Sponsor
- King Saud University
Bile Duct Stricture
Intraintestinal Extended Biliary Stents Preventing Duodenobiliary Reflux in Patients With Biliary Stricture
Metal or plastic biliary stents placement under Endoscopic Retrograde Cholangiopancreatography(ERCP) is a well-established treatment for patients with benign biliary obstruction to relieve jaundice, a palliative treatment for…
- Trial name
- NCT04550819
- Testing
- intraintestinal extended biliary stents, ordinary plastic biliary stents
- Where
- China
- Volunteers
- 724 people
- Sponsor
- Peking University Third Hospital
Dyspepsia, Heartburn
Bile Reflux Gastropathy: Prevalence and Risk Factors After Therapeutic Biliary Interventions
Bile reflux gastropathy is caused by the backward flow of duodenal fluid into the stomach. A retrospective cohort study was performed to declare if the therapeutic biliary interventions cause bile reflux gastropathy, and to…
- Conditions
- Dyspepsia, Heartburn, Bile Reflux
- Trial name
- NCT05131802
- Testing
- upper GIT endescopy
- Where
- Egypt
- Volunteers
- 288 people
- Sponsor
- Zagazig University
Ulcer, Gastric, Bile Reflux
Evaluation of Biliary Reflux After Mini-gastric Bypass With Using the Biliary Reflux Index
MGB is considered to be the best alternative to Roux-en-Y gastric bypass (RYGB) due to the shorter operation time and fewer possible complications.
- Trial name
- NCT04845438
- Testing
- fibrogastroscopy, biopsy of the gastric mucosa, microscopy biopsy materials, using Bile Reflux Index
- Where
- Russia
- Volunteers
- 122 people
- Sponsor
- Private Healthcare Institution Clinical Hospital RGD-Medicine
Cancer
The FOCCUS Study: "Focusing on Cancers Chemotherapys' Untreated Symptoms"
The aim of the study is to identify how often gastrointestinal problems interfere with quality of life as a result of treatment for cancer with chemotherapy.
- Trial name
- FOCCUS (NCT02121626)
- Where
- United Kingdom
- Volunteers
- 248 people
- Sponsor
- Royal Marsden NHS Foundation Trust
Gastroesophageal Reflux Disease, Dyspepsia
Endoscopic Tri-Modal Imaging to Distinguish Functional Dyspepsia From Reflux Disease
Endoscopic Tri-Modal Imaging which combines Narrow-band Imaging(NBI), Autofluorescence Imaging (AFI) and White-light Imaging (WLI) could be used to identify the indistinct changes in the gut caused by reflux disease,either acid…
- Conditions
- Gastroesophageal Reflux Disease, Dyspepsia, Bile Reflux
- Trial name
- NCT02685150
- Testing
- Endoscopic Tri-Modal Imaging, Omeprazole, Analysis of gastric juice
- Where
- China
- Volunteers
- 157 people, healthy volunteers welcome
- Sponsor
- Chinese PLA General Hospital
Reflux Disease, Gastro-Esophageal, Sleeve Gastrectomy
Pilot Study of Salivary Bile Acids and Pepsin as Predictive Biomarkers of Reflux Disease After Sleeve Gastrectomy
The goal of this observational study is to learn whether bile acids and pepsin in saliva can help identify adults at higher risk of developing reflux-related esophageal disease after sleeve gastrectomy, including Los Angeles…
- Conditions
- Reflux Disease, Gastro-Esophageal, Sleeve Gastrectomy, Saliva Collection, Reflux Esophagitis (RE)
- Trial name
- ABSORB (NCT07607067)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Hospital de Mataró
Pancreatitis, Cholangitis
The Patency Period of the New Plastic Anti-reflux Biliary Stent
The aim of this study is to determine the average patency period of the new anti-reflux biliary stent on patients with malignant bile duct strictures and to determine if this stent remains patent for a longer period of time…
- Trial name
- NCT01142921
- Testing
- Anti-reflux Tannenbaum biliary stent, Ordinary Tannenbaum biliary stent
- Where
- China
- Volunteers
- 16 people
- Sponsor
- Chinese University of Hong Kong
Bile Reflux
Omega Loop Gastric Bypass With And Without Anti-Reflux Sutures
This proposed trial is designed to answer the following questions: First, is biliary reflux to the distal esophagus present before OLGB and does it increase after the procedure? Second, does performing an OLGB with or without…
- Trial name
- NCT03097887
- Testing
- Omega Loop Gastric Bypass, Bilitec 2000™, V-Loc
- Where
- Austria
- Volunteers
- 100 people
- Sponsor
- Medical University of Vienna
Irritable Bowel Syndrome, Gallstone Disease
Pharmacokinetics, Bioequivalence, and Safety Study of Trimedat® 76,95 mg Orally Disintegrating Tablets and Trimedat® 100 mg Tablets in Healthy Volunteers.
This study aims to evaluate pharmacokinetic profile, safety and establish bioequivalence of the investigational drug Trimedat® 76,95 mg orally disintegrating tablets compared to the reference drug Trimedat® 100 mg tablets in…
- Conditions
- Irritable Bowel Syndrome, Gallstone Disease, GERD, Biliary Dyskinesia
- Trial name
- NCT07421011
- Testing
- Trimedat®
- Where
- Russia
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Valenta Pharm JSC
Helicobacter Pylori Infection, Peptic Ulcer
The Revolutions of Helicobacter Pylori Infection, Bacterial Density, and Histological Features After Antrectomy
Helicobacter pylori (HP) is a gram-negative bacillus responsible for one of the most common infections found in humans worldwide.
- Conditions
- Helicobacter Pylori Infection, Peptic Ulcer, Bile Reflux, Gastritis
- Trial name
- NCT00441831
- Where
- Taiwan
- Volunteers
- 65 people
- Sponsor
- Mackay Memorial Hospital
Bile Reflux Gastritis, Gastric Cancer
Study on the Effect of Bile Reflux on Gastric Cancer and Its Precancerous Lesions: a Cross-sectional Study.
To explore the effects of bile reflux on gastric cancer and its precancerous lesions, so as to better prevent the occurrence and development of gastric cancer.
- Conditions
- Bile Reflux Gastritis, Gastric Cancer, Helicobacter Pylori Infection, Intestinal Metaplasia
- Trial name
- NCT03976739
- Where
- China
- Volunteers
- 1,162 people, healthy volunteers welcome
- Sponsor
- Xijing Hospital of Digestive Diseases
Bile Duct Stricture
Suspended Overlength Biliary Stents Preventing Duodenobiliary Reflux in Patients With Biliary Stricture
Endoscopic insertion of plastic or metal stents in bile duct under endoscopic retrograde cholangiopancreatography is a well established treatment of distal malignant biliary obstruction.Biliary stents are widely used to relieve…
- Trial name
- NCT03310554
- Testing
- 26cm suspended overlength biliary stents, 30cm suspended overlength biliary stents, ordinary plastic biliary stents
- Where
- China
- Volunteers
- 117 people
- Sponsor
- Peking University Third Hospital
Common Bile Duct Gall Stones, Common Bile Duct GallStones
Rate of Duodenal-biliary Reflux Increases in Patients With Recurrent Common Bile Duct Stones
ERCP is the primary choice for removal of common bile duct stone (CBDS) currently. However, 4-24% patients underwent recurrence after successful clearance of CBDS.
- Trial name
- NCT02329977
- Testing
- standard barium meal examination
- Where
- China
- Volunteers
- 64 people
- Sponsor
- Air Force Military Medical University, China
Obesity, Morbid, Obesity, Abdominal
Long-term Follow-up After OAGB
This study follows patients who have undergone one-anastomosis gastric bypass (OAGB), a type of weight-loss surgery, to check for changes in the stomach and esophagus over time.
- Conditions
- Obesity, Morbid, Obesity, Abdominal, Ona Anastomosis Gastric Bypass, GERD
- Trial name
- NCT07125638
- Where
- Italy
- Volunteers
- 2,368 people
- Sponsor
- Azienda Sanitaria Locale Napoli 2 Nord
Stomach Cancer, Gastrectomy
Comparison Study for Bile Reflux and Gastric Stasis in Patients After Distal Gastrectomy
The purpose of this study is to evaluate the degree of bile reflux and gastric stasis according the reconstruction methods after distal subtotal gastrectomy for gastric cancer, and to find out the proper method.
- Trial name
- NCT00622804
- Testing
- Billroth-II (B-II), Roux en Y gastrojejunostomy (RY-GJ), uncut Roux en Y gastrojejunostomy
- Where
- 5 sites in South Korea
- Volunteers
- 90 people
- Sponsor
- The Catholic University of Korea