Clinical trials: Biliary Strictures
Malignant Biliary Strictures
Covered Self-expandable Metal Stents for Palliation of Malignant Biliary Strictures: Evaluation of a New Type of Stent
self-expandable metal stents for palliation of malignant biliary strictures
- Trial name
- NCT01457105
- Testing
- Endoscopic retrograde cholangiography (ERC) (ComVi biliary stent)
- Where
- Italy
- Volunteers
- 70 people
- Sponsor
- Catholic University of the Sacred Heart
Cholangiocarcinoma, Biliary Stricture
Digital Single-operator Cholangioscopy and Intraductal Ultrasound for Nonicteric Biliary Strictures
This study aims to evaluate the usefulness of disposable digital single-operator cholangioscopy (SOC) and intraductal ultrasound (IDUS) for the accurate diagnosis of indeterminate biliary stricture.
- Trial name
- Spy+IDUS (NCT06369896)
- Volunteers
- 36 people
- Sponsor
- Soonchunhyang University Hospital
Benign Biliary Strictures With Current or Prior Biliary Obstruction
Percutaneous Endoluminal Benign Biliary Laser
This study is being done to evaluate the safety and efficacy of Percutaneous transhepatic cholangioscopic (PTCS) laser incision as an ancillary therapy to traditional approaches such as balloon dilation and large drain placement…
- Trial name
- PEBBL (NCT05567003)
- Testing
- Percutaneous transhepatic cholangioscopic (PTCS) laser incision
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- University of California, Los Angeles
Biliary Tract Neoplasms
Mid-Atlantic Research Group Single-Operator Cholangioscopic Assessment of Biliary Strictures
The purpose of this study is to determine if cholangioscopically-directed biopsies provide a higher diagnostic yield for malignancy in the setting of indeterminate biliary strictures when compared to standard means of sampling.
- Trial name
- SOCABS (NCT02615210)
- Testing
- SOC-directed biopsies using the SpyGlass System
- Volunteers
- 3 people
- Sponsor
- Temple University
Bile Duct Stricture, Malignancy
Performance of FISH for the Diagnosis of Malignant Biliary Strictures in Thai Patients
Fluorescence in situ hybridization (FISH) has improved the diagnostic performance of cytology for evaluation of malignant biliary strictures in the US and Europe.
- Trial name
- NCT02442167
- Volunteers
- 101 people
- Sponsor
- Mayo Clinic
Patients With Biliary Stricture Treated During ERCP With Available MRCP and Abdominal CT Scan
Preclinical Development of a 3D Bili-MRI Reconstruction Tool and an Artificial Intelligence Algorithm to Assist Endoscopists in Performing Endoscopic Retrograde Cholangiopancreatography (ERCP)
ERCP is a complex interventional endoscopic procedure based on 2D visualization of the biliary tract. 3D modeling and AI are promising solutions to improve navigation and safety during ERCP.
- Trial name
- MAAGIE (NCT07401485)
- Testing
- retrospective study based on data already collected during routine care (no intervention)
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Obstructive Jaundice, Biliary Stricture
Evaluation of the Use of a Biodegradable Endoprothesis in the Prevention of Post-Endoscopic Retrograde CholoangioPancreatography Pancreatitis
The use of an endoprothesis in a pancreatic duct is a measure to minimize the incidence and severity of Post-Endoscopic Retrograde CholoangioPancreatography Pancreatitis.
- Conditions
- Obstructive Jaundice, Biliary Stricture, Sphincter of Oddi Dysfunction
- Trial name
- ARCHIMEDE (NCT03977779)
- Testing
- Placement of ARCHIMEDES fast biodegradable stent during the Endoscopic Retrograde CholoangioPancreatography
- Where
- 2 sites in France
- Volunteers
- 46 people
- Sponsor
- Institut Paoli-Calmettes
Alagille Syndrome
Characterization of Pulmonary Artery Stenoses in Alagille Syndrome - a Medical Record Review
Patients who have Alagille Syndrome (AGS) also frequently have blockages (or "stenoses") of their pulmonary arteries. Little is known about the degree or variability of these stenoses, or the effect of this disease on the right…
- Trial name
- NCT01515631
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Stanford University
Biliary Stricture
Factors Predicting Positive Yields on Biliary Brush Cytology During Endoscopic Retrograde Cholangiopancreatography
To determine factors associated with a positive yield of malignancy on biliary brush cytology obtained by ERCP.
- Trial name
- ERCP (NCT00894348)
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- The Cleveland Clinic
Biliary Stricture
Real-Time Cholangioscopy Artificial Intelligence Evaluation of Biliary Strictures
The purpose of this study is to demonstrate the feasibility and validity of a previously developed peroral cholangioscopy (POC) convolutional neural network (CNN) to determine the etiology of biliary strictures when used in…
- Trial name
- NCT05779436
- Where
- 2 sites in United States
- Volunteers
- 100 people
- Sponsor
- Mayo Clinic
Liver Transplantation, Transplant Recipient
Study of Sequential Perfusion of Liver Grafts to Prevent Nonanastomotic Biliary Strictures After Liver Transplantation
The study was designed to investigate whether, compared with conventional sole perfusion with high-viscosity solution of University of Wisconsin (UW), sequential perfusion of liver grafts with low-viscosity and high-viscosity…
- Trial name
- NCT01271179
- Testing
- sequential perfusion with ipv Ross solution and UW solution, sole perfusion with UW solution
- Where
- China
- Volunteers
- 141 people
- Sponsor
- Shanghai Jiao Tong University School of Medicine
Bile Duct Stricture, Bile Duct Cancer
Metal Stents (Moving Cell Stent) for Inoperable Tumors of the Bile Duct Tract
In this feasibility study (non-randomized), the applicability of a new "moving cell" biliary stents (by HILZO) in Klatskin tumors (bile duct obstruction) will be investigated.
- Trial name
- NCT03788655
- Where
- Germany
- Volunteers
- 30 people
- Sponsor
- Johannes Vermehren
Biliary Anastomotic Stenosis
Plastic Stenting Versus Retrievable Metallic Stenting for Biliary Anastomotic Stricture After Liver Transplantation
Liver transplantation is the best treatment option for patients with end-stage liver disease and early unresectable hepatocellular carcinoma.
- Trial name
- LT (NCT04144504)
- Testing
- Retrievable metallic stenting, Plastic stenting
- Where
- Hong Kong
- Volunteers
- 64 people
- Sponsor
- The University of Hong Kong
Cholangiocellular Carcinoma, Pancreatic Cancer
Radiation Stent Versus Self-expanding Metallic Stents (SEMS) for Palliative Treatment of Malignant Biliary Stricture
Malignant biliary obstruction is a common clinical condition caused by various malignancies. Currently,biliary stent implantation guided either by fluoroscopy or endoscopy has become the most important methods for relieving…
- Conditions
- Cholangiocellular Carcinoma, Pancreatic Cancer, Gallbladder Cancer, Metastatic Carcinoma
- Trial name
- NCT01320241
- Testing
- self-expandable 125I radioactive seeds-loaded-stent, self-expandable biliary nitinol alloys stent
- Where
- China
- Volunteers
- 24 people
- Sponsor
- Southeast University, China
Bile Duct Stricture
Suspended Overlength Biliary Stents Preventing Duodenobiliary Reflux in Patients With Biliary Stricture
Endoscopic insertion of plastic or metal stents in bile duct under endoscopic retrograde cholangiopancreatography is a well established treatment of distal malignant biliary obstruction.Biliary stents are widely used to relieve…
- Trial name
- NCT03310554
- Testing
- 26cm suspended overlength biliary stents, 30cm suspended overlength biliary stents, ordinary plastic biliary stents
- Where
- China
- Volunteers
- 117 people
- Sponsor
- Peking University Third Hospital
Biliary Tract Diseases
Endoscopic Treatment of Benign Biliary Strictures and Cystic Duct Leakages With a Novel Biodegradable Biliary Stent
Patients with either post-cholecystectomy bile leak or benign biliary stricture are recruited for endoscopic insertion of a biodegradable biliary stent.
- Trial name
- NCT02353286
- Testing
- Endoscopic insertion of biodegradable biliary stent
- Where
- Finland
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Tampere University Hospital
Pancreatitis, Chronic, Stricture; Bile Duct
GORE® VIABIL® Biliary Endoprosthesis in the Treatment of Benign Biliary Strictures Secondary to Chronic Pancreatitis
This study will evaluate the safety and effectiveness of the GORE® VIABIL® Biliary Endoprosthesis in the treatment of benign biliary strictures secondary to Chronic Pancreatitis (CP).
- Trial name
- VIABILITY (NCT05820009)
- Testing
- GORE® VIABIL® Biliary Endoprosthesis, GORE® VIABIL® Short Wire Biliary Endoprosthesis
- Where
- 2 sites in United States
- Volunteers
- 133 people
- Sponsor
- W.L.Gore & Associates
Biliary Stricture
Primary Cholangioscopy Versus ERCP in the Diagnosis of Biliary Strictures
The management of biliary strictures depends on their correct pre-operative evaluation which remains challenging. Despite the emerging multitudes of new diagnostic opportunities and modalities which exist today, there is still a…
- Trial name
- NCT04010734
- Testing
- Peroral Cholangioscopy and Endoscopic retrograde cholangiopancreatography
- Where
- Czechia
- Volunteers
- 66 people
- Sponsor
- University Hospital Olomouc
Primary Sclerosing Cholangitis (PSC)
Endoscopy and Primary Sclerosing Cholangitis
Primary Sclerosing Cholangitis (PSC) is a chronic, cholestatic, immune-mediated liver disease characterized by segmental inflammation, fibrosis and destruction of the intra and / or extrahepatic biliary tree.
- Trial name
- NCT06686810
- Testing
- Endoscopic Retrogradade CholangioPancreatography (ERCP)
- Where
- Italy
- Volunteers
- 118 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Bile Duct Stricture, Endoscopic Retrograde Cholangiopancreatography
Transparent Cap-assisted SpyGlass for Biliary Stricture
The transparent cap-assisted endoscope has the function of fixing field of view and increasing visual space. It has been widely used in gastrointestinal examination and treatment.
- Conditions
- Bile Duct Stricture, Endoscopic Retrograde Cholangiopancreatography, Biliary Disease, Biliary Tract Neoplasms
- Trial name
- NCT05320497
- Testing
- Transparent cap
- Where
- China
- Volunteers
- 10 people
- Sponsor
- Affiliated Hospital to Academy of Military Medical Sciences