Clinical trials: Binge-Eating Disorder
Alcohol Consumption
Effect of Acute Alcohol Intoxication on Neural Processes During Decisions to Engage in HIV Risk Behaviors
Background: People who binge drink are more likely to have risky sexual encounters, and alcohol changes brain activity associated with reward decisions related to those behaviors.
- Trial name
- NCT04360018
- Testing
- Alcohol beverage
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Pediatric Obesity, Nutrition Disorders
The Intersection Between Loss of Control Eating and Obesity: The Role of Restriction and Food Reinforcement
This study aims to determine the relationships among loss of control eating, restriction, relative reinforcing value of high energy-dense food, and obesity risk.
- Conditions
- Pediatric Obesity, Nutrition Disorders, Binge Eating, Body Weight
- Trial name
- NCT05177705
- Testing
- Restricted access task, Structured Intake
- Where
- United States
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- State University of New York at Buffalo
Binge Eating Behaviour, Eating Disorders
Biobehavioral Mechanisms of Activity and Loss of Control Eating in Children
Loss of control eating in children and adolescents is associated with a host of negative physical and psychological health outcomes and a prognostic marker for development of eating disorders.
- Conditions
- Binge Eating Behaviour, Eating Disorders, Physical Activity, Functional Magnetic Resonance Imaging (fMRI)
- Trial name
- NCT07823153
- Testing
- Go/No-go task, Visual food task, Emotion regulation task
- Where
- 3 sites in United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- The University of Texas at Dallas
Type 2 Diabetes Mellitus, Binge-Eating Disorder
Preventing Type 2 Diabetes in Black Emergent Adult
Black Americans are disproportionately affected by diabetes, with nearly double the rates of type 2 diabetes mellitus (T2DM), compared to non-Hispanic White adults.
- Conditions
- Type 2 Diabetes Mellitus, Binge-Eating Disorder, Binge Eating, Obesity
- Trial name
- NCT06848244
- Testing
- Appetite Awareness Training (AAT), Diabetes Prevention Program (DPP)
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Binge-Eating Disorder, Circadian Rhythm Disorders
The Role of the Circadian System in Binge Eating Disorder
Binge eating disorder (BED) shows prominent circadian features that suggest a delay in circadian phase, and preliminary evidence shows binge eating may be responsive to chronobiological interventions, implicating a circadian…
- Trial name
- CHRONO-BE (NCT04724668)
- Testing
- Melatonin (3hrs before DLMO), Morning light version 1, Morning light version 2
- Where
- United States
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- University of Cincinnati
Appetite, Binge Eating Behaviour
Effects of Home-Based Transcranial Direct Current Stimulation on Appetite
This randomized, placebo-controlled, double-blind, parallel-design study aims to evaluate the neurophysiological effects of home-based transcranial direct current stimulation (tDCS) on appetite in adults with binge eating…
- Conditions
- Appetite, Binge Eating Behaviour, Food Cravings
- Trial name
- NCT07757438
- Testing
- Active Home-Based tDCS
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Binge Eating, Binge-Eating Disorder
Treating Binge Eating and Obesity Digitally in Women
More than 30% of Black women with obesity binge eat. Binge eating may increase the risk for the development of metabolic syndrome and binge-eating-disorder (BED), which is associated with severe obesity.
- Conditions
- Binge Eating, Binge-Eating Disorder, Weight Gain Prevention, Obesity
- Trial name
- NCT05693896
- Testing
- Centering Appetite
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Bulimia Nervosa, Binge-Eating Disorder
Effects of Negative Affect in Individuals With Binge Eating Episodes
Binge-eating is characterized by recurrent episodes of eating large amounts of - typically high calorie - foods, eating much more rapidly than normal and until feeling uncomfortably full, as well as feeling disgusted with…
- Conditions
- Bulimia Nervosa, Binge-Eating Disorder, Obesity, Eating Disorder
- Trial name
- NCT03393039
- Testing
- Negative Affect Task
- Where
- United States
- Volunteers
- 410 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Anorexia Nervosa, Bulimia Nervosa
Eating Disorders Genetics Initiative 2
The overarching intention of the Eating Disorder Genetics Initiative 2 (EDGI2) is to increase sample size, diversity, and eating disorder phenotypes.
- Conditions
- Anorexia Nervosa, Bulimia Nervosa, Binge-Eating Disorder, Avoidant Restrictive Food Intake Disorder
- Trial name
- EDGI2 (NCT06594913)
- Testing
- Eating disorder diagnosis group
- Where
- 5 sites in United States, Australia and 3 more
- Volunteers
- 20,000 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Binge-Eating Disorder
Decision Making, Daily Experiences, and Brain Activity in Young Adult Women
The investigators are doing a study of women with and without binge-eating disorder to learn more about what happens when people engage in everyday decision-making activities.
- Trial name
- NCT04125589
- Testing
- Speaking Activity, Talking Activity
- Where
- United States
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- Mclean Hospital
Pediatric Obesity, Binge-Eating Disorder
Project THINK: Trajectories of Health, Ingestive Behaviors, and Neurocognition in Kids
Overweight/obesity and loss of control eating (characterized by the sense that one cannot control what or how much one is eating) are prevalent among children and adolescents, and both are associated with serious medical and…
- Trial name
- NCT04701671
- Testing
- Observational (not including MRI scanning), Observational (including MRI scanning)
- Where
- 2 sites in United States
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Disordered Eating
Self-Guided Personalized Treatment for Women
The investigators plan to collect preliminary data on the feasibility, acceptability, and user uptake of a personalized self-guided mobile intervention for disordered eating (DE) and test the initial clinical efficacy of this…
- Trial name
- NCT05920720
- Testing
- Self-guided Personalized Treatment
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Louisville
Binge Eating Disorder, Binge Eating
Effectiveness of a 10-week Multicomponent Intervention Combined With Parent Education on Binge Eating Behavior in Children and Adolescents
The main purpose is to investigate the effectiveness of a 10-week multicomponent camp intervention to reduce BE behavior in children and adolescents and explore in a randomized controlled setting if a parent-based…
- Conditions
- Binge Eating Disorder, Binge Eating, Loss of Control Eating, Overweight , Obesity
- Trial name
- STOB (NCT07301541)
- Testing
- A 10-week multicomponent camp intervention for children, A BED intervention for parents
- Where
- 2 sites in Denmark
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Binge Eating, Binge-Eating Disorder
EXOMIND (BTL-995) for the Reduction of Binge-eating
The goal of this clinical trial is to evaluate if the treatment with the BTL-995-rTMS device is able to reduce binge eating in adults above the age of 22 years.
- Trial name
- NCT06894615
- Testing
- Treatment with BTL-995-rTMS
- Where
- Czechia
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- BTL Industries Ltd.
Binge-Eating Disorder
EXOMIND (BTL-995) for Reduction of Binge-eating
The goal of this clinical trial is to evaluate if the treatment with the BTL-995-rTMS device is able to reduce binge eating in adults above the age of 22 years.
- Trial name
- NCT06910592
- Testing
- Treatment with BTL-995-rTMS
- Where
- Bulgaria
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- BTL Industries Ltd.
Bulimia Nervosa, Binge Eating Behaviour
Wise Eating: A Guided Digital DBT-Based Intervention for Binge Eating
Bulimia Nervosa (BN), characterized by binge eating and purging behaviors, constitutes a chronic psychiatric disorder predominantly affecting young females, characterized by high prevalence and relapse rates.
- Conditions
- Bulimia Nervosa, Binge Eating Behaviour, Anorexia Nervosa, Eating Disorders
- Trial name
- NCT07143214
- Testing
- online dialectical behavior therapy, Waitlist and psychoeducation
- Where
- China
- Volunteers
- 101 people, healthy volunteers welcome
- Sponsor
- Shanghai Mental Health Center
Eating Disorders, Psychiatric Comorbidities
Structural Brain Volumetry Changes in Eating Disorders.
The goal of this observational study is to investigate the relationship between structural brain changes and psychiatric comorbidities in individuals diagnosed with eating disorders (EDs).
- Trial name
- NCT07131852
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Assiut University
Binge-Eating Disorder, Emotional Eating
Study of Emotional Regulation and Underlying Prefrontal Activity in Binge Eating Disorder
The goal of this exploratory, interventional, multicentre study is to compare the prefrontal activity during a negative emotion regulation task in women with Binge-Eating Disorder (BED) and healthy women with and without…
- Conditions
- Binge-Eating Disorder, Emotional Eating, Healthy Volunteers
- Trial name
- EmoBED (NCT06864065)
- Testing
- Emotion regulation task (fNIRS recording during the emotional regulation task)
- Where
- 3 sites in France
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Besancon
Binge Eating Disorder, Obesity
Investigation of the Mechanisms of the Gut-brain Axis in Binge Eating and Obesity.
Binge Eating Disorder (BED) is a recently recognized eating disorder, characterized by recurrent episodes of overeating with a loss of control.
- Trial name
- Gut2Brain (NCT06823557)
- Testing
- Psychobiotic treatment
- Where
- Portugal
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Universidade do Porto
Binge Eating
EMOTE: a Smartphone Application for Binge Eating Based on DBT Skills
Binge eating, whether formally diagnosed or occurring at subthreshold levels, is associated with adverse health consequences and decreased quality of life.
- Trial name
- NCT06683456
- Testing
- eMOTE
- Where
- Portugal
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Universidade do Porto