Clinical trials: Bioavailability of Carotenoids
Oxidative DNA Damage
Biological Functions of Carotenoids in Humans
This study will examine the the efficiency fo absorption of major plant pigments, carotenoids, (lutein, beta-carotene and lycopene)and will measure the biological functions of carotenoids in healthy women in response to an 8-week…
- Trial name
- NCT00356252
- Testing
- mixed carotenoids
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Tufts University
Beta-carotene Bioavailability, Vitamin A Deficiency
Effect of SNPs in the BCMO1 Enzyme
Summary: Chronic intake of foods low in vitamin A (retinol) and provitamin A forming an unbalanced diet with little variety is common in young individuals in the United Kingdom (UK) population and can lead to subclinical…
- Trial name
- BETASNP2 (NCT02276014)
- Testing
- Beta-carotene
- Where
- United Kingdom
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- Newcastle-upon-Tyne Hospitals NHS Trust
Healthy
Bioavailability of Pepper Carotenoids in Humans
list item one, Peppers We propose to evaluate bio absorption of pepper carotenoids in a red bell-pepper or non-pungent green jalapeno pepper. The pepper will be provided in a cooked dish.
- Trial name
- NCT00636350
- Testing
- Pepper
- Where
- United States
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- Tufts University
Healthy
Bioavailability of Golden Rice Carotenoids in Humans
This investigation protocol uses an isotope reference method to evaluate bioavailability of ß-C in rice and its bioconversion to vitamin A.
- Trial name
- NCT00680355
- Testing
- golden rice, corn oil 0g, corn oil 10g
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Tufts University
Carotenoid, Bioavailability
Effect of Meal Patterning on Carotenoid Absorption From Vegetables
The purpose of this research study is to determine how different meal patterns influence the absorption of beneficial plant pigments (carotenoids) from vegetables.
- Conditions
- Carotenoid, Bioavailability, Dietary Modification
- Trial name
- S26 (NCT01856816)
- Testing
- Meal Pattern Treatment A, Meal Pattern Treatment B, Meal Pattern Treatment C
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Purdue University
Vitamin A Status
Bioavailability of Yellow Maize Carotenoids in Humans
The study hypothesis is that high ß-C yellow maize can provide vitamin A efficiently. list item one ß-C in yellow maize The study will use stable isotope labeled high ß-C yellow maize and vitamin A in a well-nourished population…
- Trial name
- NCT00636038
- Testing
- corn beta-carotene
- Where
- Zimbabwe
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Tufts University
Aging, Well Aging
Age Related Effects Consuming Phaeodactylum Tricornutum
Investigation of the microalgae Phaeodactylum as food with regard to the uptake of omega-3 fatty acids and effects on various blood parameters in relation to age.
- Trial name
- MIA_E (NCT05120791)
- Testing
- microalgae phaeodactylum, From the Microalgae phaeodactylum the extracted beta-Glucan (especially chrysolaminarin), A combination of the vegetable bouillon, the microalgae and the beta-Glucan
- Where
- Germany
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Hohenheim
Bioavailability Heathy Volunteers, Bioavailability and AUC
Bioavailability of Phlorotannins and Carotenoids Following the Intake of Crackers Fortified With Seaweed
The study aims to evaluate the bioavailability of phlorotannins and carotenoids from the seaweed Himanthalia elongata in healthy individuals after the consumption of a cracker fortified with this plant species.
- Trial name
- BIO-ALGA (NCT07508735)
- Testing
- Seaweed cracker, Control cracker
- Where
- Spain
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- National Research Council, Spain
Postprandial Carotenoid Response
Effect of Co-consuming Different Dietary Protein Sources With Salad on the Bioavailability of Carotenoids
The goal of this clinical trial is to learn if different protein types will affect carotenoid responses in humans when co-consumed with salad.
- Trial name
- NCT07795372
- Testing
- Salad only, Salad + Chicken, Salad + Tuna
- Where
- Singapore
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- National University of Singapore
Biological Availability, Carotenoids
Bioavailability of Carotenoids From Orange Juice in a Cross-over Study in Healthy Subjects.
Commercially available fruit juices are obtained after applying industrial technologies to preserve and extend the shelf-life by inactivation of microorganism and enzymes. These are traditional thermal treatment (eg.
- Conditions
- Biological Availability, Carotenoids, Lutein, Humans
- Trial name
- NCT04744233
- Testing
- Orange juice
- Where
- 2 sites in Spain
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Instituto de Ciencia y Tecnología de Alimentos y Nutrición
Healthy
The MULTINUTRIENT Maize Project: Results of Human Feeding Trial
The main objective of this human trial is the demonstration that β-carotene in fortified maize has good bioavailability as a plant source of vitamin A and that when humans ingest the biofortified product retinol levels are higher…
- Trial name
- MAIZE (NCT02373943)
- Testing
- β-carotene biofortified maize, β-carotene supplemented maize, Normal (non biofortified) maize without added β-carotene
- Where
- Spain
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Institut de Recerca Biomèdica de Lleida
Retinal Ageing
Carotenoid Supplementation and Normal Ocular Health
Normal ageing affects vision as a result of preretinal and retinal changes. Photoreceptors, the light sensitive cells in the retina, degenerate and the rods (responsible for night vision) are most susceptible to damage with…
- Trial name
- NCT02147171
- Testing
- VisionAce
- Where
- United Kingdom
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- University of Manchester
Vitamin A Deficiency
Vitamin A Bioavailability in Lactating Women With Marginal Vitamin A Status
The study will assess the relative bioavailability and bioefficacy of cryptoxanthin (CX) and beta-carotene (BC) from food sources for increasing breast milk carotenoid and retinol concentrations in lactating Bangladeshi women.
- Trial name
- NCT01420406
- Testing
- 0 mg retinol activity equivalents, 12 mg of BC, 6 mg of CX
- Where
- Bangladesh
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- USDA, Western Human Nutrition Research Center
Vitamin A Deficiency
Impact of Consumption of Orange-fleshed Sweet Potatoes on the Vitamin A Status of Bangladeshi Women of Reproductive Age
The primary purpose of this study is to determine whether daily consumption of orange-fleshed sweet potatoes increases the vitamin A status of Bangladeshi women of reproductive age.
- Trial name
- NCT00453648
- Testing
- White-fleshed sweet potatoes, Orange-fleshed sweet potatoes (boiled), Orange-fleshed sweet potatoes (fried)
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Carotenoids
Effect of the Type and Emulsification of Dietary Fat on the Carotenoids Absorption
This study is designed to assess the effects of 1) the emulsification 2) the type of dietary fat on carotenoid (CAT) absorption employing an in-vitro digestion system (Proof of Concept) and well-designed randomized controlled…
- Trial name
- NCT04323826
- Testing
- olive oil-water mixture, olive oil-water emulsion, coconut oil-water mixture
- Where
- 2 sites in Singapore
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- National University of Singapore
Focus of Study: Carotenoid Absorption
Comparison of Carotenoid Bioavailability From Fresh Papaya, Tomato and Carrot
The goal of this study is to determine if papaya fruits are an exceptionally good food source for carotenoids in humans, particularly when compared more common carotenoid sources like carrots and tomatoes.
- Trial name
- NCT01748916
- Testing
- Papaya, Carrot, Tomato
- Where
- 2 sites in United States, Costa Rica
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Cardiovascular Disease
Bioavailability of Carotenoids Added Into Processed Foods
Carotenoids are a family of pigments found abundantly in fruits and vegetables. They are responsible for the colour of many fruits and vegetables such as tomatoes, melon, peppers and orange coloured fruits and vegetables.
- Trial name
- CAROTFoods (NCT02246985)
- Testing
- Control, Vegetable bread only, Plain bread with vegetable mayonnaise
- Where
- United Kingdom
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Aberdeen
Vitamin A Deficiency
Bioefficacy of Beta-cryptoxanthin From Biofortified Maize
Since no quantitative information currently exists on how effectively the pro-vitamin A carotenoid (pVAC) β-cryptoxanthin (βCX) is converted to vitamin A (VA) in humans, this proof of principle study aims to compare the efficacy…
- Trial name
- BIOCRYPT (NCT04153968)
- Testing
- β-cryptoxanthin
- Where
- United Kingdom
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Newcastle University
Healthy
Bioavailability of Carotenoids and Flavonoids From Fresh Oranges and Orange Juice.
The study was designed as a randomized 2-way cross-over study to assess the bioavailability of carotenoids and flavonoids from sweet oranges and orange juice.
- Trial name
- NCT02380144
- Testing
- Fresh orange fruit and pasteurized fruit juice
- Where
- Germany
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Hohenheim
Bioavailability
Effect of Iron and Zinc Supplementation on B-carotene Bioavailability in Healthy Males
In vitro studies found supplemental levels of iron and zinc to inhibit the micellization and cellular uptake of β-carotene. Here, we investigated this in vivo, in a double-blind 3-arm crossover human trial.
- Trial name
- NCT05840848
- Testing
- Control beta-carotene supplement plus iron Supplement, Control beta-carotene supplement plus zinc Supplement
- Where
- Germany
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Hohenheim