Clinical trials: Bioceramic Sealer
Endodontic Disease
Evaluation of Antimicrobial Efficacy and Adaptability of Bioceramic Sealer Containing Nanoparticles
Successful endodontic treatment depends primarily on the elimination of infecting microorganisms. This is done by chemo-mechanical preparation of root canals, which is not enough and microorganisms might still survive.
- Trial name
- NCT04481945
- Testing
- bioceramic sealer
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Misr International University
Irreversible Pulpitis, Apical Periodontitis
Healing Outcomes Following Hydraulic Condensation With a Bioactive Bioceramic Sealer in Root Canal Treatment
This prospective clinical study aimed to evaluate the healing outcomes after root canal treatment using a bioceramic sealer called BioRoot RCS in combination with a technique known as hydraulic condensation.
- Trial name
- HEAL-BR (NCT07075354)
- Testing
- Hydraulic Condensation Root Canal Obturation with BioRoot RCS
- Where
- Bulgaria
- Volunteers
- 66 people
- Sponsor
- Plovdiv Medical University
Post Operative Pain
Comparison of Post Operative Pain in Resin-Based and Bioceramic Based Root Canal Sealers in Patient Presenting at Peshawar Dental College.
The goal of this clinical trial is to compare the post operative pain in Resin-Based and Bio ceramic based sealers in patients presenting at Peshawar dental college.
- Trial name
- NCT07253025
- Testing
- Resin based root canal sealer, Bioceramic based root canal sealer
- Where
- Pakistan
- Volunteers
- 180 people
- Sponsor
- Prime Foundation
Asymptomatic Apical Periodontitis
Postoperative Pain and Quality of Life Following Root Canal Treatment With Two Different Sealers
This study compares two different root canal sealers, AH Plus and BioRoot Flow, to determine whether the type of sealer used during root canal treatment affects pain after treatment and oral health-related quality of life.
- Trial name
- NCT07884799
- Testing
- AH Plus, BioRoot Flow
- Where
- Turkey (Türkiye)
- Volunteers
- 58 people
- Sponsor
- Karadeniz Technical University
Postoperative Dental Pain, Root Canal Sealers
Effect of Different Root Canal Sealers on Postoperative Pain
This randomized clinical trial aimed to evaluate postoperative pain following the use of bioceramic and epoxy resin-based root canal sealers in combination with the continuous wave of condensation technique (CWCT), addressing a…
- Conditions
- Postoperative Dental Pain, Root Canal Sealers, Asymptomatic Irreversible Pulpitis
- Trial name
- NCT06726837
- Testing
- Postoperative pain - 6th hour, Postoperative pain - 24th hour, Postoperative pain - 48th hour
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people
- Sponsor
- Dicle University
Symptomatic Irreversible Pulpitis
Comparative Evaluation of Postoperative Pain and Clinical Success
Sixty-three mandibular molars with vital pulp, symptomatic acute pain, and a Numerical Rating Scale (NRS) score of 7 or higher-requiring emergency treatment-were randomly allocated into three groups according to the preparation…
- Trial name
- NCT07133217
- Testing
- Root canal preparation with Hand Files (Dentsply Sirona), Root canal preparation with the WaveOne Gold file system (Dentsply Sirona, Ballaigues, Switzerland), Root canal preparation with the ProTaper Ultimate file system (Dentsply Sirona)
- Where
- Turkey (Türkiye)
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Ege University
Irriversible Pulpitis
Effect of Instrumentation Systems and Sealers on Postoperative Pain
The goal of this randomized clinical trial is to evaluate whether different root canal preparation systems and sealer types affect postoperative pain after root canal treatment in adult patients (18-60 years) with asymptomatic…
- Trial name
- POP (NCT07526844)
- Testing
- TruNatomy, ProTaper Gold, AH Plus
- Volunteers
- 144 people
- Sponsor
- European University of Lefke
Symptomatic Irreversible Pulpitis
Postoperative Pain After Root Canal Obturation Using Bioceramic and Calcium Hydroxide Sealers
This study is designed to find out how different root canal sealers affect pain after root canal treatment. We are comparing two types of dental sealers: bioceramic sealer and calcium hydroxide sealer.
- Trial name
- BCvsCaOH (NCT07410780)
- Testing
- CeraSeal Bioceramic Sealer, Sealapex Calcium Hydroxide Sealer
- Where
- Pakistan
- Volunteers
- 50 people
- Sponsor
- HITEC-Institute of Medical Sciences
Asymptomatic Apical Periodontitis
Effect of Calcium-Based Bioceramic Sealer and Resin-Based Sealer on Postoperative Pain
This study aims to compare the effect of calcium-based bioceramic sealer and resin-based sealer on postoperative pain in adult patients with asymptomatic apical periodontitis undergoing root canal treatment.
- Trial name
- NCT07256691
- Testing
- Resin-based sealer obturation technique, Bioceramic sealer obturation
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Fatima Memorial Hospital
Asymptomatic Vital Mandibular Molar Teeth
The Effect of Two Different Root Canal Sealers on Postobturation Pain and Clinical and Radiographical Outcome After Two-year Follow-up
Post-obturation pain evaluation(Part 1): One hundred asymptomatic mandibular molar teeth with vital pulp were randomly assigned into two groups according to the sealer used MTA Fillapex (Angelus Odontologica Industries SA…
- Trial name
- NCT05266599
- Testing
- MTA Fillapex root canal sealer, AH Plus root canal sealer
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Ege University
Endodontically Treated Teeth
Outcome of Root Canal Treatments Obturated With Calcium Silicate Based Sealers
The clinical use of a flowable premixed calcium-silicate bioceramic sealer used in association with warm carrier-based/single-cone technique will be compared with epoxy resin-based sealer with carrier-based technique.
- Trial name
- NCT05376033
- Testing
- root canal filling with Ceraseal sealer
- Where
- Italy
- Volunteers
- 109 people, healthy volunteers welcome
- Sponsor
- University of Bologna
Dental Pain, Facial Swelling
Comparing Obturation Using Bioceramic Nano-coated Gutta-percha With Bioceramic Sealer Versus Traditional Gutta-percha With Resin Sealer for Reducing Postoperative Pain and Swelling After Root Canal Treatment in Necrotic Single-rooted Teeth.
A randomized clinical trial will compare two root canal filling approaches in necrotic single-rooted teeth. The test group will receive bioceramic mono-block obturation using bioceramic nano-coated gutta-percha with a bioceramic…
- Trial name
- NCT07600099
- Testing
- Resin sealer with conventional gutta percha., Bioceramic sealer with bioceramic gutta-percha.
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Cairo University
Asymptomatic Apical Periodontitis, Root Canal Retreatment
Non-Surgical Single Visit Endodontic Retreatment in Cases With Asymptomatic Apical Periodontitis Using Bioceramic Sealer
The goal of this clinical trial is to learn if using bioceramic sealers in non surgical single visit endodontic retreatment in patients with endodontic treatment failure and asymptomatic apical periodontitis will work in…
- Trial name
- NCT06973135
- Testing
- Bioceramic sealer root canal obturation, resin sealer root canal obturation
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Saly Nazeer
Obturation
The Effect of Clinical Experience on the Quality of Obturation and Periapical Changes of Teeth Treated With Matched Cones in Combination With Bioceramic Sealer
Evaluation of the impact of clinical experience on the quality of obturation and periapical changes of clinical cases using lateral compaction with bioceramic sealers and matched cone obturation with bioceramic sealers both…
- Trial name
- NCT06260423
- Testing
- Experienced dentist using lateral compaction with bioceramic sealer., Unexperienced dentist using lateral compaction with bioceramic sealer., Experienced dentist using Single cone with bioceramic sealer.
- Where
- Egypt
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Endodontic Disease, Endodontically Treated Teeth
Outcome of Endodontic Treatment and Retreatment With a Bioceramic Sealer
This study is a prospective randomized controlled study of patients who come to the University. The aim is to evaluate the success rate of treatment and retreatment of canals using BioRoot ™ RCS cement compared with AH Plus up to…
- Trial name
- NCT04528979
- Testing
- BioRoot RCS® root canal sealer, AH Plus® root canal sealer
- Where
- Spain
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- Juan Gonzalo Olivieri
Root Canal Obturation
Root Canal Treatment With TotalFill® Bioceramic Sealer and AH Plus® Sealer
The study design is a double blinded randomized controlled trial and 170 subjects (teeth) , 85 in each of the 2 groups, will be enrolled from the patients at the NUH dental centre endodontic unit.
- Trial name
- NCT03732170
- Testing
- TotalFill® Bioceramic sealer, AH plus® sealer
- Where
- Singapore
- Volunteers
- 170 people
- Sponsor
- National University Hospital, Singapore
Periapical Periodontitis, Pulpitis
Postoperative Pain Evaluation After Obturation With Different Sealers
This study aims to evaluate the incidence and intensity of postoperative pain in patients undergoing root canal treatment on teeth diagnosed with pulpitis, pulp necrosis, or with previous endodontic treatment.
- Conditions
- Periapical Periodontitis, Pulpitis, Necorsis
- Trial name
- NCT07018284
- Testing
- AH Plus (Dentsply Sirona, Charlotte, NC, USA), NeoSealer Flo, Continuous Wave Condensation
- Where
- Spain
- Volunteers
- 270 people
- Sponsor
- University of Siena
Periapical Lesions
A Comparison Between Two Types of Sealers in the Healing of Periapical Lesions
This clinical study will evaluate the effect of BioCeramic sealer with single cone compared with the control group treated with AH Plus with lateral condensation in root canal obturation on the healing of periapical lesions.
- Trial name
- NCT06400030
- Testing
- Root canal treatment with AH Plus sealer, Root canal treatment with BioCeramic sealer
- Where
- Syria
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Damascus University
Postoperative Pain
The Effect of Different Obturation Techniques on Postobturation Pain in Single-Visit Root Canal Treatment
The goal of this prospective clinical randomized study is to evaluate the effect of different obturation techniques on postobturation pain in single-visit root canal treatment in 18-60 years old patient who present no systemic…
- Trial name
- NCT06146894
- Testing
- Single obturation technique (Bioceramic Sealer), lateral condensation technique (Bioceramic Sealer), Warm Vertical condensation technique (Bioceramic Sealer)
- Where
- Egypt
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Kafrelsheikh University
Symptomatic Irreversible Pulpitis
The Effect of XP-Endo Finisher Activation of Bioceramic Sealer on Postoperative Pain in Mandibular First Molar With Symptomatic Irreversible Pulpitis
The aim of endodontic obturation is to make a complete sealing along the length of the root canal system to ensuring the peri radicular tissue healing and sustained health.
- Trial name
- NCT06640231
- Testing
- sealer activation after cleaning and shaping with XP-Endo Finisher, negative control where canals are obturated directly without sealer activation
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Future University in Egypt