Clinical trials: Biochemical Marker
Pregnancy Anemia
Vitamin B12 Pregnancy Supplementation
Pregnancy is associated with increased requirements for iron and increased blood volume of up to 40%. Because expansion in plasma volume is higher than the increase in the mass of red blood cells, there is a fall in hemoglobin…
- Trial name
- NCT03522428
- Testing
- vitamin b12
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Mirela Zec
Healthy Participants, Placebo - Control
The Effects of Psilocybin in Healthy Volunteers: Psychological, Biochemical and Electrophysiological Biomarkers.
In this study, participants will received either psilocybin (the active ingredient found in certain mushrooms) or an inactive placebo (a look-alike tablet with no active drug).
- Conditions
- Healthy Participants, Placebo - Control, Psilocybin
- Trial name
- PSILOBIOMARKER (NCT07433452)
- Testing
- Psilocybin (drug)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Gabriella Gobbi
Supplementation, Sport
Acute Sodium Bicarbonate Supplementation in Athletes
The purpose of this study is to verify the effect of acute sodium bicarbonate (SB) and placebo (PLA) supplementation on buffering potential kinetics, physical capacity, discipline-specific performance as well as concentration of…
- Trial name
- NCT03810404
- Testing
- Sodium bicarbonate supplementation
- Where
- Poland
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Poznan University of Physical Education
Knee Osteoarthritis
Evaluation of the Effect of the "CR500 SINGLE-DOSE GEL" Medical Device in Patients With Knee Osteoarthritis (KOA)
Single arm clinical investigation, post-market confirmatory interventional to assess performance, safety and tolerability of "CR500 SINGLE-DOSE GEL" medical device in patients with knee osteoarthritis (KOA).
- Trial name
- NCT05661162
- Testing
- CR 500™ SINGLE-DOSE GEL
- Where
- Italy
- Volunteers
- 38 people
- Sponsor
- Contrad Swiss SA
Immunity
Effect of Protocatechuic Acid on Biochemical Markers of Immunity Status in Healthy Adults
The purpose of this voluntary research study is to determine if a dietary supplement containing a substance called protocatechuic acid (PCA) can change markers in blood related to immunity (a body's natural ability to fight…
- Trial name
- NCT06121362
- Testing
- Protocatechuic Acid or PCA
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Milton S. Hershey Medical Center
Chronic Rhinosinusitis, Aspirin Exacerbated Respiratory Disease
Effect of Dietary Salicylate in Aspirin Exacerbated Respiratory Disease
Aspirin-Exacerbated Respiratory Disease, or AERD, consists of aspirin sensitivity, asthma and nasal polyps. It is currently managed by chronic steroid use, multiple endoscopic sinus surgeries and/or aspirin desensitization.
- Conditions
- Chronic Rhinosinusitis, Aspirin Exacerbated Respiratory Disease, Asthma, Aspirin Sensitivity
- Trial name
- NCT01778465
- Testing
- Low salicylate diet, Normal Diet
- Where
- Canada
- Volunteers
- 7 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Arthritis
Effects of Cox-II Inhibitor on Biochemical Markers in Cardiovascular-related Adverse Effects
The selective cyclooxygenase-2 (COX-2) inhibitors have been associated with increased cardiovascular risk. The goal of the present study is to investigate the impacts of COX-2 inhibitors on biochemical indices in cardiovascular…
- Trial name
- NCT00944866
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- National Chung Hsing University
Duration of Weaning
Relevance of Biomarkers in the Process of Weaning
The purpose of the study is to examine the relevance of biochemical markers (specific pulmonary and cardiac markers and markers of endogenous stress) in the process of weaning in patients with artificial ventilation.
- Trial name
- NCT01341561
- Where
- Germany
- Volunteers
- 100 people
- Sponsor
- Heidelberg University
Migraine Disorders
Predict the Response to Acute Treatment of Migraine With Rimegepant 75 mg
Tools to predict which patients could better respond to abortive CGRP target therapy are still lacking. We propose to investigate if biochemical (salivary CGRP) and neurophysiological (evoked potentials) biomarkers can recognize…
- Trial name
- NCT05888766
- Testing
- Rimegepant 75 milligrams
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- University of Roma La Sapienza
HCV Infection
Study of the Role of Dendritic Cells in the Recurrence of Hepatitis C After Liver Transplantation. Analysis of Hepatitis C Virus (HCV) Quasispecies Evolution.
Re-infection of the liver graft occurs universally following liver transplantation for HCV-induced end stage liver disease. Interestingly, the manifestation of HCV infection ranging from an asymptomatic carrier state to rapid…
- Trial name
- NCT00213707
- Where
- France
- Volunteers
- 30 people
- Sponsor
- University Hospital, Strasbourg, France
Multiple Sclerosis
Longitudinal Pharmacokinetic, Pharmacodynamic, Immunological, and Biochemical
This is an open-label study of patients with relapsing forms of Multiple Sclerosis designed to assess the longitudinal pharmacokinetic, pharmacodynamic, immunological, and biochemical sample collection with MRI and relapse…
- Trial name
- NCT01330498
- Where
- United States
- Volunteers
- 229 people
- Sponsor
- John F. Foley, MD
Osteoarthritis, Hip, Ambulation Difficulty
Effects of Denosumab on Periprosthetic Bone After Total Hip Arthroplasty
The primary objective is to study the effect of Denosumab on Bone Mineral Density, Standardised Uptake Value and bone metabolism in patients with total hip arthroplasty.
- Trial name
- NCT01630941
- Testing
- denosumab
- Where
- Sweden
- Volunteers
- 64 people
- Sponsor
- Hans Mallmin
Oophorectomy, Oxidative Stress
Role of Oxidative Stress in Ovarian Tissue After CO2-pneumoperitoneum Application-induced I/R
Because of cellular changes in response to ischemia and a following period of reperfusion, damages to organs and different tissues occur.
- Conditions
- Oophorectomy, Oxidative Stress, Ischemia Reperfusion Injury
- Trial name
- NCT04493983
- Testing
- laparoscopic salpingo-oophorectomy, Laparoscopic bilateral salpingo-oophorectomy
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Ismet Hortu
Osteoporosis
Thai Traditional Massage Increases Biochemical Marker of Bone Formation in Postmenopausal Women
To investigate the skeletal effect of Thai traditional massage by examining the changes in biochemical markers of bone turnover.
- Trial name
- NCT01627028
- Testing
- Thai traditional massage
- Where
- Thailand
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Postoperative Cognitive Dysfunction, Alzheimer Disease
Tau Pathology in the Brain After Hip or Knee Replacement Surgery
The goal of this observational study is to study whether major surgery is linked to changes in the brain that are typical of Alzheimer's disease.
- Conditions
- Postoperative Cognitive Dysfunction, Alzheimer Disease, Tauopathies, Neuroinflammation
- Trial name
- TAU-PET (NCT07871487)
- Testing
- Hip or Knee Arthroplasty Under Spinal Anesthesia
- Where
- Sweden
- Volunteers
- 30 people
- Sponsor
- Uppsala University Hospital
Type 1 Diabetes
Evaluation of Some Biochemical Markers of Bone Turnover in Childern and Adolescents With Type 1 Diabetes
Type 1 diabetes is associated with many longterm complications as retinopathy,neuropathy and nephropathy. Recently, several studies have linked type 1 diabetes to bone fragility.Studies conducted on patients with type 1 diabetes…
- Trial name
- NCT05892848
- Testing
- serum ostecalcin,serum sclerostin and parathroid profile
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Sohag University
Rosacea
Evaluation of the Inhibitory Effects of Topical Ivermectin on Markers of Rosacea Specific Inflammation.
This study will assess the role of topical Ivermectin 1% cream and its effect on protease and antimicrobial peptide expression and on the skin microbiome (the microorganisms that live on the skin) in rosacea.
- Trial name
- NCT02806414
- Testing
- Ivermectin
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- University of California, San Diego
Acute Myocardial Infarction With ST Elevation
Analysis of the Efficacy of Cardiac Ischemic Postconditioning With New Clinical End-points Using Novel Biomarkers
The aim of the present study was to investigate the efficacy of ischemic postconditioning in acute myocardial infarction patients. The safety of patients enrolled in the study was ensured during the entire study.
- Trial name
- NCT04824716
- Testing
- Postconditioning, Percutaneous coronary intervention
- Where
- 3 sites in Hungary
- Volunteers
- 100 people
- Sponsor
- Peter Ferdinandy
Infertility
Pregnancy/Implantation Rates Using a Day 3 Score Versus Graduated Embryo Score Plus a Biochemical Marker (sHLA-G)
Objective: To compare pregnancy rates and implantation rates when embryos are selected based on a single Day 3 (D.3) score vs. a GES score plus sHLA-G expression.
- Trial name
- NCT00680238
- Testing
- Human derived FSH
- Volunteers
- 214 people, healthy volunteers welcome
- Sponsor
- University of Stellenbosch
Osteoporosis, Osteoporosis (Senile)
Epidemiological Study of Osteoporosis in the Elderly Population of Shandong Province
At present, there is little epidemiological information on osteoporosis in the elderly population of Shandong Province, especially the lack of systematic research on the role of bone metabolism and biochemical indicators in the…
- Trial name
- NCT06915935
- Testing
- dualenergy X-ray absorptiometry
- Where
- China
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- The Second Hospital of Shandong University