Clinical trials: Biofilm Formation
Orthodontic Appliances, Removable, Dental Plaque
Cleaning Methods for Clear Aligners
The goal of this clinical trial is to learn which cleaning method best removes bacteria from clear plastic aligners. Clear aligners are removable orthodontic trays worn to straighten teeth.
- Conditions
- Orthodontic Appliances, Removable, Dental Plaque, Biofilms, Disinfection
- Trial name
- NCT07610603
- Testing
- Toothbrushing of clear aligner with water, Chlorhexidine gluconate 0.2% oral rinse, Effervescent aligner cleaning tablet
- Where
- Saudi Arabia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Riyadh Elm University
Mandibular Prosthesis User
Assessment of the Impact of Probiotics on Biofilm Formation on Removable Acrylic Dentures
The aim of this study is to evaluate the effect of PIP toothbrush cleaner® on the microbial composition and Candida albicans colonization of denture biofilm formation.
- Trial name
- NCT02736994
- Testing
- PIP toothbrush cleaner® (Chrisal, Lommel, Belgium)., Corega Tabs Anti-bacteria®, Water
- Where
- Belgium
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Biofilm Formation
Randomized and Controlled Clinical Trial to Evaluate Bacterial Adhesion on Multi-Im® Transepithelial Components
This study evaluates the efficacy of Mutli-Im® transepithelial components in the inhibition of bacterial adhesion. The control group will be the Multi-Im® transepithelial component with the conventional surface (Multi-IM®…
- Trial name
- NCT03554876
- Testing
- Multi-Im Machined transepithelial component., Multi-Im Nanogolden transepithelial component, Multi-Im Ti-Golden transepithelial component
- Where
- Spain
- Volunteers
- 17 people
- Sponsor
- Fundación Eduardo Anitua
Dental Biofilm Accumulation
Effect of Enzyme-containing Lozenge on Dental Biofilm Formation, Composition and Functionality
A double-blind, placebo-controlled randomized cross-over trial evaluating the effect of enzyme-containing lozenge on in vivo and in situ grown dental biofilm accumulation.
- Trial name
- NCT06142409
- Testing
- Enzyme containing lozenge
- Where
- Denmark
- Volunteers
- 34 people
- Sponsor
- Novozymes A/S
Dental Caries
Effect of Sour Cherry Anthocyanins on Healthy Human Saliva
The experiment is based on earlier research where it was proven that chewing gum usage with anthocyanin rich sour cherry extract significantly reduces the amount of human salivary alpha-amylase in unstimulated saliva samples and…
- Trial name
- NCT05406011
- Testing
- Pelleted sour cherry (anthocyanin) containing chewing gum usage., Pelleted chewing gum for stimulated saliva sampling., Scaling
- Where
- Hungary
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Debrecen
Chronic Gingivitis, Chronic Gingivitis, Plaque Induced
Efficacy of a Rinse Containing Sea Salt and Lysozyme on Biofilm and Gingival Health
This study evaluates the addition of a mouth rinse containing sea salt, xylitol and lysozyme to standardized oral health practices on biofilm formation and gingival health in a group of young adults.
- Trial name
- NCT03329105
- Testing
- Sea Salt Mouth Rinse, Standardized Oral Health Practices
- Where
- Canada
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Saskatchewan
Denture Hygiene
Microbial Evaluation of Denture Cleaning and Overnight Storage
Clinical guidelines for denture care are available, but evidence for optimal nocturnal storage is missing. The investigators (Duyck J., Vandamme K., Teughels W.) therefore performed a study (submitted for publication) to evaluate…
- Trial name
- NCT02454413
- Testing
- denture brushing with water and soap, ultrasonic denture cleaning, cleansing tablet
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Orthodontic Aligner Material, Enamel Demineralization
Development of Biofunctional 3D-Printed Orthodontic Aligners With Antimicrobial and Remineralizing Properties
Clear orthodontic aligners are widely used due to their esthetics and patient comfort; however, prolonged wear may promote biofilm accumulation and enamel demineralization.
- Conditions
- Orthodontic Aligner Material, Enamel Demineralization, Dental Biofilm Formation, Clear Aligner Material Properties
- Trial name
- 3D-BIOALIGN (NCT07603427)
- Testing
- Modified 3D-Printed Orthodontic Aligner Resin
- Where
- Iraq
- Volunteers
- 400 people
- Sponsor
- University of Baghdad