Clinical trials: Biological Samples
Obesity, Metabolic Abnormalities
Obesity Medicine Bank of the Quebec Heart and Lung Institute - Laval University (IUCPQ-ULaval)
Obesity medicine, or bariatric medicine, focuses not only on the biological and behavioral aspects, but also on the environmental and social factors that contribute to the development of obesity.
- Conditions
- Obesity, Metabolic Abnormalities, Health
- Trial name
- NCT07472608
- Testing
- Behavioral and Pharmacological Treatments
- Where
- Canada
- Volunteers
- 25,000 people
- Sponsor
- Institut universitaire de cardiologie et de pneumologie de Québec, University Laval
Biological Samples
Human Internal BIOASTER's Samples Collection
BIOASTER is a Technological Research Institute dedicated to microbiology and infectious diseases. BIAOSTER s areas of expertise are organized around four research programs: 1/ Antimicrobials; 2/ Vaccines; 3/ Microbiota; 4/…
- Trial name
- HIBISCUS (NCT06602388)
- Testing
- Biological sampling
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Bioaster
Multiple Myeloma, Plasma Cell Myeloma
S0120, Studying Blood and Bone Marrow Samples From Patients With Monoclonal Gammopathy of Undetermined Significance, Multiple Myeloma, or Plasmacytoma
RATIONALE: Studying samples of blood and bone marrow in the laboratory from patients with monoclonal gammopathy of undetermined significance, multiple myeloma, or plasmacytoma may help doctors learn more about changes that occur…
- Conditions
- Multiple Myeloma, Plasma Cell Myeloma, Precancerous Condition
- Trial name
- NCT00900263
- Testing
- cytogenetic analysis, microarray analysis, biologic sample preservation procedure
- Where
- 69 sites in United States
- Volunteers
- 375 people
- Sponsor
- SWOG Cancer Research Network
Healthy
The Use of Aging Biomarkers in Saliva, Based on DNA Methylation Status in Elovl2 to Predict Biological Age
There is a big change in our understanding of aging in recent years. Recent researches has revealed clock-like patterns of epigenetic change across in humans. The aging involves a timed epigenetic reprogramming.
- Trial name
- NCT03734419
- Volunteers
- healthy volunteers welcome
- Sponsor
- HKGepitherapeutics
Melanoma (Skin)
S9431: Studying Genes and Immune Response in Tumor Samples From Patients With Locally Advanced or Metastatic Melanoma
RATIONALE: Studying samples of tumor tissue and blood from patients with cancer in the laboratory may help doctors learn more about changes that occur in DNA and identify biomarkers related to cancer.
- Trial name
- NCT00898183
- Testing
- gene expression analysis, polymorphism analysis
- Volunteers
- 91 people
- Sponsor
- SWOG Cancer Research Network
Metabolic Syndrome
Establishment of the Human Intestinal and Salivary Microbiota Biobank - Metabolic Syndrome
This is a prospective, clinical, monocentric study aimed to collect biological samples and study microbiota from subjects suffering from metabolic syndrome and from healthy volunteers.
- Trial name
- BIOMIS-DIM (NCT04698096)
- Testing
- Biological sample collection, Questionnaire, Medical examination
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- Azienda Ospedaliero-Universitaria Consorziale Policlinico di Bari
Hepatitis-Associated Aplastic Anemia
Collection of Biological Samples From Patients With Hepatitis-Associated Aplastic Anemia
This study will collect samples of blood, stool, bone marrow, or other tissues from patients with hepatitis-associated aplastic anemia to investigate a possible association between exposure to viruses and the development of…
- Trial name
- NCT00050115
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Kidney Cancer
Studying Biomarkers in Samples From Younger Patients With Wilms Tumor
RATIONALE: Studying samples of tissue and urine from patients with cancer in the laboratory may help doctor learn more about changes that occur in DNA and identify biomarkers related to cancer.
- Trial name
- NCT01542333
- Testing
- gene expression analysis, proteomic profiling, reverse transcriptase-polymerase chain reaction
- Volunteers
- 20 people
- Sponsor
- Children's Oncology Group
Ann Arbor Stage I Childhood Hodgkin Lymphoma, Ann Arbor Stage II Childhood Hodgkin Lymphoma
Collecting and Storing Biological Samples From Young Patients With Hodgkin?s Lymphoma
This laboratory study is collecting and storing samples of tissue and blood from young patients with Hodgkin's lymphoma. Collecting and storing samples of tumor tissue and blood from patients with cancer to study in the…
- Conditions
- Ann Arbor Stage I Childhood Hodgkin Lymphoma, Ann Arbor Stage II Childhood Hodgkin Lymphoma, Ann Arbor Stage III Childhood Hodgkin Lymphoma, Ann Arbor Stage IV Childhood Hodgkin Lymphoma
- Trial name
- NCT00900250
- Testing
- Cytology Specimen Collection Procedure
- Where
- 183 sites in United States, Australia and 2 more
- Volunteers
- 1,271 people
- Sponsor
- Children's Oncology Group
Fertility
Creation of a Biobank of Fertile Men
Collection and conservation of human biological material from fertile subjects, i.e. men with previous parenthood (normospermic men, natural fathers).
- Trial name
- NCT06189677
- Testing
- Observation of biological characteristics of fertile men
- Where
- 2 sites in Italy
- Volunteers
- 2,000 people
- Sponsor
- IRCCS San Raffaele
Parkinson Disease
Non-drug Treatment Study in Parkinson's Disease Patients and Healthy Volunteers to Collect Biological Samples in Order to Assess ex Vivo the Activity of Candidate Therapies and Develop Novel Analytical Methods for Biomarkers
This is a non-drug study in patients with Parkinson's Disease (PD) and healthy volunteers to process and analyze their blood and optional cerebrospinal fluid (CSF) samples ex vivo, or outside of their body, to further develop…
- Trial name
- IRIS-CLE-LRRK2 (NCT05837130)
- Testing
- Blood sample collection and an optional cerebrospinal fluid (CSF) collection, Blood sample collection
- Where
- 4 sites in France
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Servier
Ganglioneuroblastoma, Localized Resectable Neuroblastoma
Biomarkers in Tumor Tissue Samples From Patients With Newly Diagnosed Neuroblastoma or Ganglioneuroblastoma
This research trial studies biomarkers in tumor tissue samples from patients with newly diagnosed neuroblastoma or ganglioneuroblastoma.
- Conditions
- Ganglioneuroblastoma, Localized Resectable Neuroblastoma, Localized Unresectable Neuroblastoma, Regional Neuroblastoma
- Trial name
- NCT00904241
- Testing
- Cytology Specimen Collection Procedure, Laboratory Biomarker Analysis
- Where
- 259 sites in United States, Australia and 6 more
- Volunteers
- 10,000 people
- Sponsor
- Children's Oncology Group
Multiple Osteochondromas
Registry of Multiple Osteochondromas
REM is a retrospective and prospective registry, finalized for care and research purposes. It is articulated in main sections - strongly related and mutually dependent on each other - corresponding to different data domains…
- Trial name
- REM (NCT04133285)
- Where
- Italy
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- Luca Sangiorgi
SARS (Severe Acute Respiratory Syndrome), COVID-19
Sero-epidemiological Study of the SARS-CoV-2 Virus Responsible for COVID-19 in France
On January 2020, the discovery of a new coronavirus (SARS-CoV-2) was officially announced by the Chinese health authorities and the World Health Organization (WHO).
- Trial name
- CORSER (NCT04325646)
- Testing
- Human Biological samples
- Where
- 21 sites in France
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- Institut Pasteur
Lung Cancer
Feasibility of re Biopsies at Progression
Feasibility of new biological and histological samples at progression in patients with advanced or metastatic Non Small Cell Lung Cancer (NSCLC). A recent paper from Professor Sequist and coll.
- Trial name
- GFPC-REBIOP (NCT02086071)
- Testing
- re biopsy
- Where
- 9 sites in France
- Volunteers
- 100 people
- Sponsor
- Groupe Francais De Pneumo-Cancerologie
Rare Disorders
Establish a "Taiwan Rare Disorder Tissue Bank", to Collect and Repost Biological Samples and Disease Information From Patients With Rare Disorders
Even though rare disorders usually have limited case numbers, they have induced huge impacts on patients and their families, and has heavily burdened on our society and healthcare system as well.
- Trial name
- NCT01384305
- Volunteers
- 500 people
- Sponsor
- China Medical University Hospital
Gene Insertions, Gene Deletion
Gene Biobank of Sports Injuries
Preserve biological samples and gene extracts of all sports medicine-related diseases. To study related gene mutation sites and regulation. To study related molecular mechanisms and signaling pathways.
- Trial name
- NCT04997629
- Where
- China
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- Peking University Third Hospital
Healthy
Drone Biological Samples Transport vs Walking (DBT - Drone Biology Transport)
The transport of biological samples is a key step in the pre-analysis process in health facilities and must meet quality requirements (NF:EN:ISO 151989) to ensure that samples are transported in are transported in good…
- Trial name
- DBT (NCT05957497)
- Testing
- Biological samples transport and analysis
- Where
- France
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University Hospital, Caen
Gestational Diabetes
Construction and Biological Study of Blood and Placenta Samples Associated With Gestational Diabetes Mellitus
Gestational diabetes mellitus (GDM) is a type of diabetes mellitus with normal glucose metabolism before pregnancy. Pregnant women with prepubertal diabetes have complicated clinical experiences, and the effects of severe disease…
- Trial name
- NCT05148130
- Testing
- oral glucose tolerance test
- Where
- China
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Oncologic Disease, Hematologic Diseases
Molecular Characterizazion and Biological Samples Centralisation of Patients Affected by Oncoematolofic Pathology
Currently, the molecular characterization of onco-hematological, onco-immunological and hematological diseases, at onset or in relapse, of patients with suspected diagnosis afferent to the CROP centers, is done through…
- Trial name
- NCT06304194
- Testing
- Analysis of biological samples
- Where
- 3 sites in Italy
- Volunteers
- 340 people
- Sponsor
- Meyer Children's Hospital IRCCS