Clinical trials: Biological Samples
Multiple Osteochondromas
Registry of Multiple Osteochondromas
REM is a retrospective and prospective registry, finalized for care and research purposes. It is articulated in main sections - strongly related and mutually dependent on each other - corresponding to different data domains…
- Trial name
- REM (NCT04133285)
- Where
- Italy
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- Luca Sangiorgi
Infection Viral
COVID-19 Biological Samples Collection
The coronavirus disease 2019 (COVID-19) outbreak is now considered as a public health emergency of international concern by the World Health Organization.
- Trial name
- COLCOV19-BX (NCT04332016)
- Testing
- biological samples collection
- Where
- France
- Volunteers
- 615 people
- Sponsor
- University Hospital, Bordeaux
Autosomal Dominant Polycystic Kidney Disease (ADPKD), Advanced-Chronic Kidney Disease (CKD)
Establishment of the Human Intestinal and Salivary Microbiota Biobank - Kidney Diseases
This is a prospective, clinical, multicentre study aimed to collect biological samples and study microbiota from subjects suffering from chronic kidney disease and from healthy volunteers.
- Conditions
- Autosomal Dominant Polycystic Kidney Disease (ADPKD), Advanced-Chronic Kidney Disease (CKD), Diabetic Kidney Disease (DKD), IgA Nephropathy (IgAN)
- Trial name
- BIOMIS-Nefro (NCT04689074)
- Testing
- Biological sample collection, Questionnaire, Medical examination
- Where
- 2 sites in Italy
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Azienda Ospedaliero-Universitaria Consorziale Policlinico di Bari
Drone Transport, Biological Samples
Validation of the Transport of Biological Material by Drone
The Hospital Group of Territory Somme Littoral Sud, through its biology sector and in partnership with the company DELIVRONE, aims to engage in the experiment of transporting biological samples by means of a drone platform.
- Conditions
- Drone Transport, Biological Samples, Unmanned Aerial System
- Trial name
- TRANS-AIRGHT (NCT05885568)
- Testing
- blood sampling, drone transportation, car transportation
- Where
- France
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Pneumocystis
Non Invasive Diagnosis of Pneumocystis Pneumonia
Incidence and morbi-mortality of Pneumocystis pneumonia (PCP) are increasing. Early and fast diagnosis and treatment improve PCP prognosis.
- Trial name
- DANIPOP (NCT03613025)
- Testing
- Sampling of non-invasive and/or non-targeted respiratory tract specimens
- Where
- France
- Volunteers
- 98 people
- Sponsor
- University Hospital, Grenoble
Healthy Volunteers
Generation of Biological Samples Positive to Hydrochlorothiazide for Anti-doping Control
Background: Hydrochlorothiazide is a diuretic that inhibits the reabsorption of sodium and chloride in the renal tubules, thus increasing the excretion of water.
- Trial name
- HCTZ (NCT04197622)
- Testing
- Hydrochlorothiazide
- Where
- Spain
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- Parc de Salut Mar
Infant, Child Development
National Children s Health Study
Patterns of illness among children in the United States and other industrially developed nations have changed substantially during the past 100 years.
- Conditions
- Infant, Child Development, Biological Samples
- Trial name
- NCT00852904
- Where
- 4 sites in United States
- Volunteers
- 9,942 people
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Women Diagnosed With Infertility
The Effect of the Mediterranean Diet on Fatty Acids in Biological Fluids of Women Undergoing Infertility Treatment
The aim of this study was to examine the effect of the Mediterranean diet, which is accepted as one of the adequate and balanced nutrition models today, as well as serum and follicular fluid fatty acid profile and implantation…
- Trial name
- NCT06559904
- Testing
- Mediterranean diet
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people
- Sponsor
- Trakya University
Solid Tumors, Hematologic Malignancy
Prospective Procurement of Tumor Tissue to Identify Novel Therapeutic Targets and Study the Tumor Microenvironment
Background: Many advances have been made in cancer treatments, but more research is needed. Comparing samples of cancerous tissue to samples of normal, noncancerous tissues may help find differences between them.
- Conditions
- Solid Tumors, Hematologic Malignancy, Gastrointestinal Cancer, Liver Cancer
- Trial name
- NCT05600933
- Where
- United States
- Volunteers
- 1,200 people
- Sponsor
- National Cancer Institute (NCI)
Ehlers-Danlos Syndrome
Registry of Ehlers-Danlos Syndrome
RED is a retrospective and prospective registry, finalized for care and research purposes. It is articulated in main sections - strongly related and mutually dependent on each other - corresponding to different data domains…
- Trial name
- RED (NCT04133272)
- Where
- Italy
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Luca Sangiorgi
Sexually Transmitted Infections (Not HIV or Hepatitis), HIV Infections
Overcoming Geography With Technology: Medical Drones Project
In this study, the investigators shall evaluate the use unmanned air vehicles (medical drones) to deliver ART to adult patients eligible/enrolled in community DSD models in Bufumira Islands, Kalangala district.
- Conditions
- Sexually Transmitted Infections (Not HIV or Hepatitis), HIV Infections, COVID-19
- Trial name
- NCT05259761
- Testing
- Unmanned ariel vehicle
- Where
- Uganda
- Volunteers
- 1,450 people, healthy volunteers welcome
- Sponsor
- Makerere University
Biological Availability
Bioavailability of the Microconstituents of Natural Chios Mastiha in Healthy Adults.
Mastiha is a natural product from the tree Pistacia lentiscus var. Chia (Anacardiaceae) growing exclusively in the Southern part of Chios Island.
- Trial name
- NCT02847117
- Testing
- Mastiha
- Where
- Greece
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Harokopio University
B-Cell Non-Hodgkin Lymphoma (NHL)
Biological Analysis of MABs in NHL in a Translational Prospective Observational Study Within Italian Clinical Practice
This a prospective, multicenter, observational pharmacological translational study designed to investigate the biological and imaging correlates of treatment with novel monoclonal antibodies (NMABs) in patients with B-cell…
- Trial name
- BIO-FIL_MAB (NCT07767799)
- Testing
- WP1 - Task 1 - Liquid analyses, WP1 - Task 2 - Immunological analyses, WP1 - Task 3 - Tumor tissue analyses
- Where
- 20 sites in Italy
- Volunteers
- 1,000 people
- Sponsor
- Fondazione Italiana Linfomi - ETS
Tuberculosis
Biological Samples Obtained by Leukapheresis Induced by Two BCG Vaccinations in BCG-naïve Healthy Adults in the US
This protocol will use leukapheresis to collect lymphocytes to study immune responses following vaccination with BCG in BCG-naïve participants.
- Trial name
- (A-051) (NCT03175380)
- Testing
- bacillus Calmette-Guérin
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Aeras
Kidney Cancer
Studying Biomarkers in Samples From Younger Patients With Wilms Tumor
RATIONALE: Studying samples of tissue and urine from patients with cancer in the laboratory may help doctor learn more about changes that occur in DNA and identify biomarkers related to cancer.
- Trial name
- NCT01542333
- Testing
- gene expression analysis, proteomic profiling, reverse transcriptase-polymerase chain reaction
- Volunteers
- 20 people
- Sponsor
- Children's Oncology Group
Pulpal Inflammation
Characterization of Pulp Inflammation: an Observational Study Using Biological Samples Collected During Routine Dental Care
Background: Vital pulp therapy (VPT) is a cornerstone of minimally invasive dentistry and aims to preserve pulp vitality whenever clinically feasible.
- Trial name
- INFLAPULP (NCT07533396)
- Volunteers
- 1,200 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Rare Disorders, Sarcoma of Bone and Connective Tissue
Characterization of the Methylation Profile of Stored Human Samples
The project, funded by the PNRR under Mission 4 "Education and Research," aims to strengthen the network of Italian biobanks by improving data management in accordance with the FAIR principles (Findable, Accessible…
- Conditions
- Rare Disorders, Sarcoma of Bone and Connective Tissue, Inflammatory Articular Diseases
- Trial name
- DNAmetCRB (NCT07573072)
- Where
- Italy
- Volunteers
- 90 people
- Sponsor
- Istituto Ortopedico Rizzoli
Bone and Joint Infection
Consitution Of A Biological Collection From Samples From The Gut Microbiote In Patients Having A Bone Or Joint Infection Treated By A Suppressive Subcutaneous Antibiotherapy With Betalactamine
Optimal surgical therapy (debridement in chronic osteomyelitis; device exchange in patients with chronic prosthetic joint infection [PJI]) could be sometimes non-feasible, especially in the elderly population.
- Trial name
- NCT03611634
- Testing
- BIOLOGICAL COLLECTION FROM THE GUT MICROBIOTE
- Where
- France
- Volunteers
- 20 people
- Sponsor
- Hospices Civils de Lyon
Periodontitis
Periodontitis and Inflammation: Study on Biological Samples
Periodontitis is a major public health problem because it is widespread in the adult population. It leads to the irreversible destruction of the anchoring tissues of the teeth, and represents a modifiable risk factor for systemic…
- Trial name
- CB-PARO2 (NCT06012019)
- Testing
- Biological sampling in Periodontitis Case, Biological sampling in Gingivitis Case, Biological sampling in Control Case
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Clostridium Difficile Infection, Multi Drug Resistant Organisms
Establishment of the Human Intestinal and Salivary Microbiota Biobank - Gastrointestinal Diseases
This is a prospective, clinical, multicentre study aimed to collect biological samples and study microbiota from subjects with Clostridium Difficile (CDI), subjects affected by Multi Drug Resistant Organisms (MDRO) infection…
- Conditions
- Clostridium Difficile Infection, Multi Drug Resistant Organisms, Chronic Inflammatory Bowel Disease, Irritable Bowel Syndrome
- Trial name
- BIOMIS-Gastr (NCT04698148)
- Testing
- Biological sample collection, Questionnaire, Medical examination
- Where
- 3 sites in Italy
- Volunteers
- 225 people, healthy volunteers welcome
- Sponsor
- Azienda Ospedaliero-Universitaria Consorziale Policlinico di Bari