Clinical trials: Biological Samples, open to volunteers
Autoimmune Bullous Dermatosis, Dysimmune Dermatological Diseases
Clinico-biological Collection of Autoimmune, Dysimmune or Auto-inflammatory Dermatological Diseases
The aim of this project is to start a biological and clinical collection of patients presenting autoimmune, dysimmune or auto-inflammatory dermatological diseases.
- Conditions
- Autoimmune Bullous Dermatosis, Dysimmune Dermatological Diseases, Auto-inflammatory Dermatological Diseases, Skin Diseases
- Trial name
- TekAPo (NCT06387654)
- Testing
- Blood sampling, Remainders of samples taken as part of the treatment
- Where
- France
- Volunteers
- 800 people
- Sponsor
- University Hospital, Toulouse
Acute Myeloblastic Leukemia
Determination of Epigenetic Markers of Acute Myeloblastic Leukemia in Elderly Patients
The main objective of this study is to identify epigenetic markers specific to abnormal myeloid cells in patients with acute myeloid leukemia (AML) by analyzing the methylation of circulating cell-free DNA in plasma.
- Trial name
- LAMME (NCT07250217)
- Testing
- Epigenetic markers
- Where
- 2 sites in France
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Groupe Hospitalier de la Region de Mulhouse et Sud Alsace
Healthy, Cancer
Archival of Human Biological Samples in CU-Med Biobank
CU-Med Biobank collaborates with different researchers for collecting and distributing human biospecimens and clinical data for assisting scientific research.
- Conditions
- Healthy, Cancer, Heart Diseases, Neurological Diseases or Conditions
- Trial name
- NCT04706481
- Testing
- Specimen Collection
- Where
- Hong Kong
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
B-Cell Non-Hodgkin Lymphoma (NHL)
Biological Analysis of MABs in NHL in a Translational Prospective Observational Study Within Italian Clinical Practice
This a prospective, multicenter, observational pharmacological translational study designed to investigate the biological and imaging correlates of treatment with novel monoclonal antibodies (NMABs) in patients with B-cell…
- Trial name
- BIO-FIL_MAB (NCT07767799)
- Testing
- WP1 - Task 1 - Liquid analyses, WP1 - Task 2 - Immunological analyses, WP1 - Task 3 - Tumor tissue analyses
- Where
- 20 sites in Italy
- Volunteers
- 1,000 people
- Sponsor
- Fondazione Italiana Linfomi - ETS
Genetic Diseases, Genetic Syndrome
Rapid Whole Genome Sequencing Study
Rapid Whole Genome Sequencing (rWGS) has proven to provide much faster diagnoses than traditional clinical testing, including clinical Whole Exome Sequencing (WES) and standard Whole Genome Sequencing (WGS).
- Trial name
- rWGS (NCT03385876)
- Testing
- Genomic sequencing and molecular diagnostic results, if any
- Where
- United States
- Volunteers
- 100,000 people, healthy volunteers welcome
- Sponsor
- Rady Pediatric Genomics & Systems Medicine Institute
Biological Samples
Human Internal BIOASTER's Samples Collection
BIOASTER is a Technological Research Institute dedicated to microbiology and infectious diseases. BIAOSTER s areas of expertise are organized around four research programs: 1/ Antimicrobials; 2/ Vaccines; 3/ Microbiota; 4/…
- Trial name
- HIBISCUS (NCT06602388)
- Testing
- Biological sampling
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Bioaster
Periodontitis, Trisomy 21
Periodontitis and Inflammation in Children With Down Syndrome/Trisomy 21: Study on Biological Samples
Since 2018, the Chicago Classification of Periodontal Diseases and Conditions, has listed Down syndrome (DS)/trisomy 21 (T21) as a systemic disease with periodontal implications.
- Trial name
- NT21 (NCT05970965)
- Testing
- Biological sampling
- Where
- France
- Volunteers
- 18 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Nervous System Diseases
Collection of Biological Samples From Patients With Rare Neurological Diseases
The aim of this project is to improve biological collections of patients presenting rare neurological disorders with known or suspected autoimmune origin.
- Trial name
- EXPLAINEUR (NCT04698421)
- Testing
- Blood collection on admission and longitudinally
- Where
- France
- Volunteers
- 1,000 people
- Sponsor
- University Hospital, Toulouse
Obesity, Metabolic Abnormalities
Obesity Medicine Bank of the Quebec Heart and Lung Institute - Laval University (IUCPQ-ULaval)
Obesity medicine, or bariatric medicine, focuses not only on the biological and behavioral aspects, but also on the environmental and social factors that contribute to the development of obesity.
- Conditions
- Obesity, Metabolic Abnormalities, Health
- Trial name
- NCT07472608
- Testing
- Behavioral and Pharmacological Treatments
- Where
- Canada
- Volunteers
- 25,000 people
- Sponsor
- Institut universitaire de cardiologie et de pneumologie de Québec, University Laval
Oncologic Disease, Hematologic Diseases
Molecular Characterizazion and Biological Samples Centralisation of Patients Affected by Oncoematolofic Pathology
Currently, the molecular characterization of onco-hematological, onco-immunological and hematological diseases, at onset or in relapse, of patients with suspected diagnosis afferent to the CROP centers, is done through…
- Trial name
- NCT06304194
- Testing
- Analysis of biological samples
- Where
- 3 sites in Italy
- Volunteers
- 340 people
- Sponsor
- Meyer Children's Hospital IRCCS
Echinococcosis
Collection of Biological Samples From Patients With Echinococcosis and Implementation of a Home-made PCR Method
Echinococcosis is a zoonotic disease caused by Echinococcus species. Diagnosis currently relies on imaging, serology and microscopy, but microscopy is time-consuming, has limited sensitivity and cannot distinguish between…
- Trial name
- Echino_home (NCT07715435)
- Testing
- Collection of biological samples from echinococcosis patients for the development of a home-based PCR protocol for diagnostic use.
- Where
- Italy
- Volunteers
- 120 people
- Sponsor
- Azienda Ospedaliera SS. Antonio e Biagio e Cesare Arrigo di Alessandria
Solid Tumors, Hematologic Malignancy
Prospective Procurement of Tumor Tissue to Identify Novel Therapeutic Targets and Study the Tumor Microenvironment
Background: Many advances have been made in cancer treatments, but more research is needed. Comparing samples of cancerous tissue to samples of normal, noncancerous tissues may help find differences between them.
- Conditions
- Solid Tumors, Hematologic Malignancy, Gastrointestinal Cancer, Liver Cancer
- Trial name
- NCT05600933
- Where
- United States
- Volunteers
- 1,200 people
- Sponsor
- National Cancer Institute (NCI)
Condition
Intermountain INSPIRE Registry
To collect biological samples, clinical information and laboratory data from patients diagnosed with any healthcare-related conditions who are seen at facilities affiliated with Intermountain Healthcare, including patients and…
- Trial name
- NCT02450006
- Where
- United States
- Volunteers
- 50,000 people, healthy volunteers welcome
- Sponsor
- Intermountain Health Care, Inc.
Gynecological Cancer, Immunotherapy
Detection of Circulating Therapeutic Monoclonal Antibodies in Biological Samples of Gynecological Cancer Patients.
Quantification of anti PD-1 mAbs in cancer patients is extremely important to monitor pharmacokinetics and effectiveness of immunotherapy.
- Trial name
- IMMUNO_ASSAY (NCT06797479)
- Testing
- Blood samples for the analysis of sildenafil in plasma
- Volunteers
- 12 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
SARS CoV 2 Infection
Collection of Additional Biological Samples From Potentially COVID-19 Patients for Monitoring of Biological Parameters Carried Out as Part of the Routine
Patients infected with SARS-CoV-2 can present with a wide range of manifestations clinical conditions, ranging from no symptoms to serious or chronic illness.
- Trial name
- CEB Covid-19 (NCT06144333)
- Testing
- RIPH2
- Volunteers
- 7,500 people
- Sponsor
- CerbaXpert
Lymphoma and Acute Lymphoblastic Leukemia
Collection of Biological Samples From Patients Treated With CAR-T Cells for Hematological Malignancies
Development of CAR-T cell against CD19 B lymphoma and Acute Lymphoblastic Leukemia leaded to 2 authorized medication: Yescarta and Kymriah.
- Trial name
- CAR-T BANK (NCT04290000)
- Testing
- additional biological samples during CAR-T CELL treatment
- Where
- France
- Volunteers
- 300 people
- Sponsor
- University Hospital, Montpellier
Ollier Disease, Maffucci Syndrome
Registry of Ollier Disease and Maffucci Syndrome
REM is a retrospective and prospective registry, finalized to care and research. It is articulated in main sections - strongly related and mutually dependent on each other - corresponding to different data domains: personal…
- Trial name
- ROM (NCT04134572)
- Where
- Italy
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Luca Sangiorgi
Normal Physiology
NIEHS Repository of Stored Biological Samples for Future Use
Background: Laboratory tests that use blood and urine can provide a great deal of information about human health and disease. To develop even better tests and to improve the ways samples are handled for testing researchers need…
- Trial name
- NCT05666739
- Where
- United States
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- National Institute of Environmental Health Sciences (NIEHS)
Pediatric Brain Tumors, Genomics
GenoDrugP 2025: Study on Three-dimensional Models Derived From Brain Tumors in Pediatric Patients
Central nervous system tumours are the most common solid tumours and the leading cause of cancer mortality in children, with high biological and prognostic heterogeneity.
- Conditions
- Pediatric Brain Tumors, Genomics, Epigenetic
- Trial name
- NCT07417072
- Testing
- Genomic DNA analysis of biological samples
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- Meyer Children's Hospital IRCCS
Cardiac Arrest, Sepsis
Repository for Sepsis and Postresuscitation Samples
The objective of this study is to find a new therapeutic strategy by investigating the serial serum samples of patients with sepsis or postresuscitation state.
- Trial name
- NCT01670383
- Where
- South Korea
- Volunteers
- 500 people
- Sponsor
- Seoul National University Hospital