Clinical trials: Biological Samples, open to volunteers
Obesity, Metabolic Abnormalities
Obesity Medicine Bank of the Quebec Heart and Lung Institute - Laval University (IUCPQ-ULaval)
Obesity medicine, or bariatric medicine, focuses not only on the biological and behavioral aspects, but also on the environmental and social factors that contribute to the development of obesity.
- Conditions
- Obesity, Metabolic Abnormalities, Health
- Trial name
- NCT07472608
- Testing
- Behavioral and Pharmacological Treatments
- Where
- Canada
- Volunteers
- 25,000 people
- Sponsor
- Institut universitaire de cardiologie et de pneumologie de Québec, University Laval
Biological Samples
Human Internal BIOASTER's Samples Collection
BIOASTER is a Technological Research Institute dedicated to microbiology and infectious diseases. BIAOSTER s areas of expertise are organized around four research programs: 1/ Antimicrobials; 2/ Vaccines; 3/ Microbiota; 4/…
- Trial name
- HIBISCUS (NCT06602388)
- Testing
- Biological sampling
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Bioaster
Multiple Osteochondromas
Registry of Multiple Osteochondromas
REM is a retrospective and prospective registry, finalized for care and research purposes. It is articulated in main sections - strongly related and mutually dependent on each other - corresponding to different data domains…
- Trial name
- REM (NCT04133285)
- Where
- Italy
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- Luca Sangiorgi
Oncologic Disease, Hematologic Diseases
Molecular Characterizazion and Biological Samples Centralisation of Patients Affected by Oncoematolofic Pathology
Currently, the molecular characterization of onco-hematological, onco-immunological and hematological diseases, at onset or in relapse, of patients with suspected diagnosis afferent to the CROP centers, is done through…
- Trial name
- NCT06304194
- Testing
- Analysis of biological samples
- Where
- 3 sites in Italy
- Volunteers
- 340 people
- Sponsor
- Meyer Children's Hospital IRCCS
Colorectal Cancer, Esophageal Cancer
Gastrointestinal Biomarkers in Tissue and Biological Fluid Samples From Colorectal Cancer Patients
RATIONALE: Studying samples of tissue, blood, urine, stool, and other biological fluids from patients with cancer and from healthy volunteers undergoing colonoscopy or endoscopy may help doctors identify and learn more about…
- Conditions
- Colorectal Cancer, Esophageal Cancer, Gastric Cancer, Pancreatic Cancer
- Trial name
- NCT00899626
- Where
- 2 sites in United States
- Volunteers
- 5,000 people
- Sponsor
- Vanderbilt University Medical Center
Ollier Disease, Maffucci Syndrome
Registry of Ollier Disease and Maffucci Syndrome
REM is a retrospective and prospective registry, finalized to care and research. It is articulated in main sections - strongly related and mutually dependent on each other - corresponding to different data domains: personal…
- Trial name
- ROM (NCT04134572)
- Where
- Italy
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Luca Sangiorgi
Paediatric Malignancies
Iatrogenic Effects of Treatment for Childhood Cancer Constitution of a Biological Samples Bank
The constitution of a biological samples bank, attached to epidemiological studies Cohort F-CCSS on iatrogenic effects of treatment of childhood cancer, will identify genetic variants that can modulate the iatrogenic risks of…
- Trial name
- BIO-F (NCT02666625)
- Testing
- saliva samples, blood samples
- Where
- 3 sites in France
- Volunteers
- 10,000 people
- Sponsor
- Gustave Roussy, Cancer Campus, Grand Paris
Autoimmune Bullous Dermatosis, Dysimmune Dermatological Diseases
Clinico-biological Collection of Autoimmune, Dysimmune or Auto-inflammatory Dermatological Diseases
The aim of this project is to start a biological and clinical collection of patients presenting autoimmune, dysimmune or auto-inflammatory dermatological diseases.
- Conditions
- Autoimmune Bullous Dermatosis, Dysimmune Dermatological Diseases, Auto-inflammatory Dermatological Diseases, Skin Diseases
- Trial name
- TekAPo (NCT06387654)
- Testing
- Blood sampling, Remainders of samples taken as part of the treatment
- Where
- France
- Volunteers
- 800 people
- Sponsor
- University Hospital, Toulouse
Malignant Neoplasm
Germ-Line Mutations in Blood and Saliva Samples From Patients With Cancer
This research trial studies germ-line mutations in blood and saliva samples from patients with cancer. Studying samples of blood and saliva from patients with cancer in the laboratory may help doctors learn more about how…
- Trial name
- NCT02280161
- Testing
- cytology specimen collection procedure
- Where
- United States
- Volunteers
- 2,000 people
- Sponsor
- Jonsson Comprehensive Cancer Center
Genetic Diseases, Genetic Syndrome
Rapid Whole Genome Sequencing Study
Rapid Whole Genome Sequencing (rWGS) has proven to provide much faster diagnoses than traditional clinical testing, including clinical Whole Exome Sequencing (WES) and standard Whole Genome Sequencing (WGS).
- Trial name
- rWGS (NCT03385876)
- Testing
- Genomic sequencing and molecular diagnostic results, if any
- Where
- United States
- Volunteers
- 100,000 people, healthy volunteers welcome
- Sponsor
- Rady Pediatric Genomics & Systems Medicine Institute
Li-Fraumeni Syndrome, Li-Fraumeni-Like Syndrome
Registry of Li Fraumeni and Li Fraumeni Like Syndromes
ReLF is a retrospective and prospective registry, finalized for care and research purposes. It is articulated in main sections - strongly related and mutually dependent on each other - corresponding to different data domains…
- Trial name
- ReLF (NCT04982744)
- Where
- 2 sites in Italy
- Volunteers
- 200 people
- Sponsor
- Istituto Ortopedico Rizzoli
Periodontitis, Trisomy 21
Periodontitis and Inflammation in Children With Down Syndrome/Trisomy 21: Study on Biological Samples
Since 2018, the Chicago Classification of Periodontal Diseases and Conditions, has listed Down syndrome (DS)/trisomy 21 (T21) as a systemic disease with periodontal implications.
- Trial name
- NT21 (NCT05970965)
- Testing
- Biological sampling
- Where
- France
- Volunteers
- 18 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Parkinson's Disease
A US Study That Observes How Parkinson's Disease Changes Over Time in Patients Who Still Have Movement Symptoms Despite Taking Parkinson's Medications
This is an observational study in which data are collected and studied from Parkinson's disease patients who have movement symptoms despite taking standard Parkinson's medications.
- Trial name
- NCT07330258
- Testing
- Standard of Care
- Where
- 27 sites in United States
- Volunteers
- 300 people
- Sponsor
- Bayer
Stevens-Johnson Syndrome, Lyell Syndrome
Drug Reactions Sampling (COLLECTIONTOXIDERMIES)
Intro: Dermatology department of Henri Mondor Hospital (Creteil, France), is a reference center for toxic bullous diseases and severe cutaneous drug reactions (Stevens-Johnson syndrome (SJS), Lyell syndrome (toxic epidermal…
- Conditions
- Stevens-Johnson Syndrome, Lyell Syndrome, Drug Reactions, AGEP
- Trial name
- NCT03659227
- Where
- France
- Volunteers
- 500 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Cytotoxicity
Biological Evaluation of Orthopedic Materials: An In Vitro Study Using Patient-Derived Human Samples
The anterior cruciate ligament (ACL) is the primary stabilizer of the knee joint, and ACL injuries are highly prevalent, particularly among physically active and athletic individuals.
- Trial name
- RAISE (NCT07671521)
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- Stefano Zaffagnini
Genetic Diseases
Rady Children's Institute Genomic Biorepository
Rady Children's Institute for Genomic Medicine (RCI) will collect biological samples (such as blood), derived genomic sequences (from DNA and RNA), and clinical features in a Biorepository as a standardized resource for future…
- Trial name
- NCT02917460
- Testing
- Genomic sequencing and molecular diagnostic results, if any
- Where
- United States
- Volunteers
- 102,000 people, healthy volunteers welcome
- Sponsor
- Rady Pediatric Genomics & Systems Medicine Institute
Cancer Risk
A Lifetime Partnership With Patients Who Have or May be at Risk of Having Cancer
This is not a treatment study. The overall objective is to develop an improved standard of care through studying blood, tissue, biological, etc. samples, that patients have allowed researchers to procure.
- Trial name
- NCT03617939
- Testing
- Biospeciman Collection, Survey Assessments, Medical Chart Reviews
- Where
- 6 sites in United States
- Volunteers
- 20,000 people
- Sponsor
- University of Colorado, Denver
B-Cell Non-Hodgkin Lymphoma (NHL)
Biological Analysis of MABs in NHL in a Translational Prospective Observational Study Within Italian Clinical Practice
This a prospective, multicenter, observational pharmacological translational study designed to investigate the biological and imaging correlates of treatment with novel monoclonal antibodies (NMABs) in patients with B-cell…
- Trial name
- BIO-FIL_MAB (NCT07767799)
- Testing
- WP1 - Task 1 - Liquid analyses, WP1 - Task 2 - Immunological analyses, WP1 - Task 3 - Tumor tissue analyses
- Where
- 20 sites in Italy
- Volunteers
- 1,000 people
- Sponsor
- Fondazione Italiana Linfomi - ETS
Echinococcosis
Collection of Biological Samples From Patients With Echinococcosis and Implementation of a Home-made PCR Method
Echinococcosis is a zoonotic disease caused by Echinococcus species. Diagnosis currently relies on imaging, serology and microscopy, but microscopy is time-consuming, has limited sensitivity and cannot distinguish between…
- Trial name
- Echino_home (NCT07715435)
- Testing
- Collection of biological samples from echinococcosis patients for the development of a home-based PCR protocol for diagnostic use.
- Where
- Italy
- Volunteers
- 120 people
- Sponsor
- Azienda Ospedaliera SS. Antonio e Biagio e Cesare Arrigo di Alessandria
Creation of an Italian Network of Biobanks of Rare Diseases
ScATtEred Rare Disease Biobanks: a Model of Sample/Data Collection With susTainablE and Shared Criteria
Rare diseases (RDs) have been defined by the European Union (EU) as life-threatening or chronically debilitating conditions affecting less than 1 person in 2000.
- Trial name
- SATELLITES (NCT06782230)
- Where
- Italy
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- IRCCS Policlinico S. Donato