Clinical trials: Biomechanical Changes
Lumbar Fusion, Lumbar Spinal Fusion Surgery
Clinical and Biomechanics Research in Core Muscles After Lumbar Fusion Surgery
Lumbar fusion has been widely used for spinal disorders when conservative treatment has failed. However, a number of studies have reported that the rate of re-operation is high for lumbar fusion surgery.
- Trial name
- NCT01703338
- Where
- Taiwan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Duchenne Dystrophy Muscular
Biomechanical and Morphological Changes in Dystrophic Muscle
The loss of ability to walk in many children with DMD (Duchenne muscular Dystrophy) is a pejorative event. Biomechanical and morphological unknowledge about the loss of the walk ability in children with DMD is an obstacle in…
- Trial name
- MARCHE-DMD (NCT02472990)
- Where
- 10 sites in France
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University Hospital, Brest
Diabetic Peripheral Neuropathy
Walking Function in Diabetic Peripheral Neuropathy
The purpose of this study is to 1) examine the differences in walking function and movement patterns between individuals with diabetic peripheral neuropathy and healthy adults with no known conditions; 2) examine if receiving…
- Trial name
- NCT05965336
- Testing
- Clinical Evaluation, Evaluation of Passive Ankle Stiffness, Gait Biomechanics
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Florida Institute for Human and Machine Cognition
Anterior Cruciate Ligament Injuries
Biomechanical Mechanism of the Change of the Gait Touch Information After ACL Rupture
High incidence rate of knee osteoarthritis and gait analysis are important for early assessment of biomechanics. ACL injury is an ideal clinical model for studying knee osteoarthritis.
- Trial name
- NCT04464330
- Testing
- no intervention
- Where
- China
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Peking University Third Hospital
Non-specific Chronic Low Back Pain
Relationships Between Muscle Activity, Soft Tissue Changes, and Movement Strategies in Individuals With Chronic Low Back Pain
This study aims to explore, in patients with chronic non-specific low back pain (cnsLBP), the relationships between lumbar muscle activity, structural and morphological characteristics of the paraspinal muscles, and movement…
- Trial name
- E-LBP (NCT07806253)
- Testing
- Supervised Progressive Walking Test
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Rennes 2
Pregnancy
Corneal Biomechanics During Pregnancy
It is known that intraocular pressure changes during pregnancy. Collagen structure changes during pregnancy to enable softening of the symphysis, whitening of the birth chanel, and, thus, ultimately to enable delivery of a child.
- Trial name
- CorvisPreg (NCT04433689)
- Testing
- Non-Contact measurement of corneal properties
- Where
- Switzerland
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Glaucoma; Drugs
CATS Tonometer IOP Reduction Latanoprost Verses Timolol
Topical Prostaglandin Analog vs Betablocker - Corneal Biomechanical Evaluation using CATS Tonometer Prism
- Trial name
- NCT04178863
- Testing
- CATS Tonometer, Latanoprost
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Intuor Technologies, Inc.
Stroke, Healthy
Walking With the EksoNR in Stroke Patients and Healthy Controls: Biomechanical Changes and User Experience.
Further studies are needed to provide more detailed information on the potential effects of robotic gait training in general, as well as on the influence on gait movement patterns in particular.
- Trial name
- NCT05334030
- Testing
- High Swing Assistance, Neutral Swing Assistance, High Swing Resistance
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Vrije Universiteit Brussel
Stress Fractures, Bone Geometry
Bone Geometry, Strength, and Biomechanical Changes in Runners With a History of Stress Fractures
Stress fractures are a common and debilitating injury for a variety of athletes however current evidence does not clearly allow easy prediction of athletes at risk for a first fracture.
- Conditions
- Stress Fractures, Bone Geometry, Bone Strength, Biomechanical Changes
- Trial name
- NCT00766077
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Utah
Traumatic Brain Injury, Concussion, Brain
" Acute Brain Changes After Repetitive Headers in Soccer and the Effects of a Protective Device "
Soccer, the most popular sport in the world, exposes players to repeated head impacts and concussions, due to contact with another player or with the ground.
- Trial name
- Soccer-BRAIN (NCT04426188)
- Testing
- Heading series, Magnetic Resonance Imaging (MRI), Cognitive computerized assessment
- Where
- France
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- University Hospital, Bordeaux
Low Back Pain
Evaluation of the Erector Spinae Muscle in Different Position and the Change After Receiving Myofascial Release.
The purpose of this experiment is to evaluate whether MyotonPRO can quantify the changes in the muscle characteristics of the erector spinae in different postures and after myofascial relaxation, and to test the validity of the…
- Trial name
- NCT05666557
- Testing
- manual erector spinae myofascial realease, self-myofascial release technique
- Where
- Taiwan
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- China Medical University Hospital
Menstrual Cycle, Passive Stretching
Biomechanical Changes During Menstrual Cycle
The aim of the work is to assess the effect of the menstrual cycle on the biomechanical properties of the muscles. The study will be conducted among young women aged 20-25 with a regular menstrual cycle.
- Conditions
- Menstrual Cycle, Passive Stretching, Hamstring Muscles
- Trial name
- NCT03979326
- Testing
- Static stretching
- Where
- Poland
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Medical University of Silesia
Pelvic Pain
Biomechanical Changes in Women With Chronic Pelvic Pain
Chronic pelvic pain (CPP), a frequent complaint in clinical gynaecology, is defined as cyclic or acyclic pain located in the pelvis, persisting for 6 months or more, and severe enough to cause functional incapacity that requires…
- Trial name
- biomechanical (NCT03740932)
- Testing
- Study group (group A)
- Where
- Egypt
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Cairo University
Muscle Tightness, Muscle Strain
Changes in the Quadriceps Muscle After Dry Needling Treatment
The present study aims to examine the mechanical changes following dry needling of the quadriceps muscle. To this end, structural and mechanical changes in quadriceps muscle activity will be measured using M-mode ultrasound.
- Trial name
- NCT06396741
- Testing
- The quadriceps muscle will be punctured with ultrasound control
- Where
- Spain
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Prof. Dr. Daniel Pecos Martín
Biomechanical Changes, Gait Biomechanics
The Effect of Lateral Wedge Insoles on Lower Limb Biomechanics, Muscle Activity and Knee Adduction Moment During Walking and Running
The aim of this prospective, randomized, single-group interventional study is to use quantitative methods to investigate the acute effects of using lateral-wedge insoles on lower extremity biomechanics, muscle activation…
- Conditions
- Biomechanical Changes, Gait Biomechanics, Gait Analysis in Healthy Subjects, Running Kinematics
- Trial name
- NCT07639411
- Testing
- 3D Movement Analysis, Force Plate, Electromyography (EMG)
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Ankara Yildirim Beyazıt University
Conjunctivitis, Allergic, Keratoconus
Corneal Biomechanical Changes of Allergic Conjunctivitis
By measuring and comparing the corneal biomechanical parameters of normal people, patients with allergic conjunctivitis, keratoconus, whether allergic conjunctivitis causes changes in corneal biomechanics can be explored, and…
- Trial name
- NCT04299399
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Zhongshan Ophthalmic Center, Sun Yat-sen University
Healthy
Structure and Function of the Human Tongue
This study will use magnetic resonance imaging (MRI) and ultrasound to examine changes in tongue volume and blood circulation during tongue exercises that require the use of different tongue muscle movements and contractions.
- Trial name
- NCT00007137
- Where
- United States
- Volunteers
- 165 people, healthy volunteers welcome
- Sponsor
- National Institutes of Health Clinical Center (CC)
Healthy
Rowing Biomechanics - Effects of (In)Stability and Fatigue
Rowing simulators are frequently used by rowers, when on-water training is impossible or limited. While such devices are highly valuable to maintain rowers' fitness, a concern was raised about extensive simulator usage.
- Trial name
- RowBio (NCT03253900)
- Testing
- Stable rowing simulator, Slides based rowing simulator, Tilt board based rowing simulator
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- University of Primorska
Low Back Pain, Pregnancy
Association of Biomechanical Changes and Weight Gain Throughout Pregnancy
Low back and posterior pelvic pain are common in pregnant females. Previous studies have demonstrated disability and it is estimated that all women experience some degree of musculoskeletal discomfort during pregnancy.
- Trial name
- NCT01315860
- Testing
- Postural Analysis
- Where
- 2 sites in United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Nova Southeastern University
Poly Cystic Ovarian Syndrome, Polycystic Ovary Syndrome (PCOS)
Biomechanical Changes in Females with Poly Cystic Ovarian Syndrome
Polycystic ovarian syndrome (PCOS) is a prevalent endocrine disorder that causes an inversion of the normal luteinizing hormone (LH) to follicle-stimulating hormone (FSH) ratio.
- Trial name
- NCT06673901
- Testing
- Measurments
- Where
- Egypt
- Volunteers
- 95 people, healthy volunteers welcome
- Sponsor
- Cairo University