Clinical trials: Biomechanical Phenomena
Pain, Acute
Exploration of Gait Biomechanics and Muscle Pain of the Lower Extremity
This interventional study aims to test gait biomechanics in healthy individuals with and without experimental muscle pain in the lower extremities.
- Trial name
- NCT06411197
- Testing
- Hypertonic saline injection, Isotonic saline injection
- Where
- Denmark
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Kristian Kjær Petersen
Ankle Injuries, Ankle Inversion Sprain
Effects of Gait Retraining With Auditory Feedback
There is evidence to support individuals with chronic ankle instability (CAI) have altered gait biomechanics which may lead to re-injury and poor patient outcomes.
- Trial name
- NCT04302961
- Testing
- Auditory Feedback, No Feedback
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- University of North Carolina, Charlotte
Diabetic Foot
Diabetic Foot School and Biomechanics
The primary aim of the study is to establish a diabetic foot school. The secondary aim is to compare the effects of the training given to diabetic foot patients within the scope of the diabetic foot school, on sensory, balance…
- Trial name
- NCT05431660
- Testing
- education and exercise protocol about diabetic foot, control group
- Volunteers
- 50 people
- Sponsor
- Ankara Yildirim Beyazıt University
Spinal Cord Injuries, Fatigue; Muscle, Heart
Fatigue Induced by Overground Wheelchair Propulsion in Persons With a Spinal Cord Injury: Upper Limb Saving or Straining?
What are the implications of wheelchair propulsion-induced fatigue for the development of shoulder pain and how can this knowledge improve prevention programs? With this project, the "Shoulder Health and Mobility group" of the…
- Trial name
- NCT03153033
- Testing
- Fatigue protocol
- Where
- Switzerland
- Volunteers
- 50 people
- Sponsor
- Swiss Paraplegic Research, Nottwil
Healthy Aging
Effects of Different Guiding Strategies on Biomechanics of Human Movement.
With regards to the increase in the aging population globally, how to build up a successfully aging society has become the main issue in health care and socioeconomic.
- Trial name
- NCT05362214
- Where
- Taiwan
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- National Cheng-Kung University Hospital
Chronic Ankle Instability, Lateral Ankle Sprain
Biomechanics and Intrinsic Foot Muscle Roles in Subjects With Chronic Ankle Instability
The current study involves a prospective interventional study that primarily intends to compare foot joint loadings of participants with chronic ankle instability (CAI) with those of subjects who recovered after an ankle sprain…
- Trial name
- NCT05815576
- Testing
- Intrinsic foot muscle fatigue
- Where
- Belgium
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Université Catholique de Louvain
Ankle Fractures, Post-traumatic Osteoarthritis
Custom Dynamic Orthoses to Reduce Articular Contact Stress
The proposed study evaluates the effect of carbon fiber brace design on forces across the ankle. Research suggests that ankle arthritis develops following ankle fracture due, in part, to elevated forces on the cartilage.
- Conditions
- Ankle Fractures, Post-traumatic Osteoarthritis, Osteoarthritis Ankle
- Trial name
- PRMRP FPA CT (NCT05209347)
- Testing
- Carbon Fiber Custom Dynamic Orthosis (CDO)
- Where
- United States
- Sponsor
- University of Iowa
Eye Diseases
Development of an IT Tool Able to Identify Ocular Conditions
The aim of the study is to use machine learning to develop an IT tool able to differentiate between eye conditions analysing corneal biomechanical data.
- Trial name
- NCT05973617
- Testing
- Measurement of corneal biomechanical properties
- Volunteers
- healthy volunteers welcome
- Sponsor
- Aston University
Healthy Subject
Francis Biomechanics Study
This study aims to evaluate the effect of a range of pre-formed orthoses on function of the foot and leg to generate technical data on how the individual insoles impact gait, distribution of load and stability in a healthy…
- Trial name
- NCT03662399
- Testing
- Insoles, Standard shoe
- Where
- Belgium
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Reckitt Benckiser Healthcare (UK) Limited
Anomalous Coronary Artery Origin, Anomalous Coronary Artery Arising from the Opposite Sinus
New Patient-specific Functional Assessment of the Anomalous Aortic Origin of Coronary Arteries.
Anomalous Aortic Origin of the Coronary Arteries (AAOCA) is a rare congenital disease that may cause sudden death in young subjects.
- Conditions
- Anomalous Coronary Artery Origin, Anomalous Coronary Artery Arising from the Opposite Sinus, Anomalous Coronary Artery Course, Anomalous Coronary Artery with Aortic Origin and Course Between the Great Arteries
- Trial name
- NECESSARY (NCT05159791)
- Testing
- Invasive coronary blood flow assessment and simulations and fluid dynamic patient specific simulation
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- IRCCS Policlinico S. Donato
Ankle Stiffness
Effects of Dry Needling the Calf Muscles on Biomechanics and Muscle Function in Individuals With Restricted Dorsiflexion
The goal of this observational study is to learn about the acute effects of dry needling the soleus muscle in individuals with limited ankle mobility
- Trial name
- NCT07474948
- Testing
- Dry needling
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Dayton
Biomechanical Phenomena
Lumbopelvic Movement Control: Effect of Injury History, and the Role of Cortical Control and Its Practical Application 1
Lumbopelvic movement control is crucial for movement stability during weight loading training, and also an important risk factor for the occurrence and recurrence of low back pain (LBP).
- Trial name
- NCT04786717
- Testing
- core muscle training, movement control training, combined imagery and movement control training
- Where
- Taiwan
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- National Yang Ming Chiao Tung University
Rheumatoid Arthritis, Healthy Controls
MusculRA: The Effects of Rheumatoid Arthritis on Skeletal Muscle Biomechanics
Persons with rheumatoid arthritis (RA) suffer from increased disability and mortality, in part resulting from skeletal muscle impairments.
- Trial name
- MusculRA (NCT04226131)
- Testing
- Blood Draw, Disease Activity (DAS-28) Assessment, Skeletal Muscle Mitochondrial Respiratory Capacity
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Duke University
Extubation Failure, Mechanical Ventilation
Swallowing Assessment for Predicting Extubation Failure in Critically Ill Patients
Extubation failure, defined as the need for reintubation after planned removal of the endotracheal tube, occurs in up to 20% of critically ill patients and is associated with prolonged mechanical ventilation, longer intensive…
- Conditions
- Extubation Failure, Mechanical Ventilation, Critical Illness
- Trial name
- APEX (NCT07659275)
- Where
- Brazil
- Volunteers
- 800 people
- Sponsor
- Universidade Federal de Pernambuco
Sleep Apnea, Obstructive
Virtual Surgery of the Upper Airways
Obstructive sleep apnea (OSA) is a sleep related breathing disorder caused by repetitive collapses of the upper airways resulting in impaired breathing, oxygen desaturation and sleep disturbances.
- Trial name
- VirtuOSA (NCT04829201)
- Testing
- functional septorhinoplasty or oropharyngeal/orthognathic surgery
- Where
- 2 sites in Norway
- Volunteers
- 30 people
- Sponsor
- Norwegian University of Science and Technology
Arthritis Knee, Gait Biomechanics
Muscles Strength and Gait Parameteres After TKA
Total Knee Arthroplasty (TKA) is actually the most effective treatment option for patients with end-stage osteoarthritis (OA). However, nearly 20% of patients who underwent TKA remain unsatisfied with their clinical outcome.
- Conditions
- Arthritis Knee, Gait Biomechanics, Total Knee Arthroplasty, Muscle Strength
- Trial name
- NCT06061367
- Where
- Poland
- Volunteers
- 100 people
- Sponsor
- Medical University of Warsaw
Osteochondral Defects of Talus, Gait Analysis
Gait Pattern Analysis After Arthroscopic Treament of Osteochondral Defects of Talus
The study will investigate alterations in post-surgical gait patterns among patients who have undergone all arthroscopic microfracture and biological scaffold implementation surgery for the osteochondral lesions of talus.
- Conditions
- Osteochondral Defects of Talus, Gait Analysis, Microfracture Procedure, Biological Scaffold
- Trial name
- NCT07161128
- Testing
- arthroscopic microfracture and biological scaffold implementation for osteochondral defects of talus
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Gazi University
Multiple Sclerosis, Ataxia
"Evaluation of Usability and Safety of the Self-balancing Walking System Atalante in Patients With Multiple Sclerosis"
Multiple sclerosis (MS) is the most prevalent chronic inflammatory disease of the central nervous system (CNS), affecting more than 2 million people worldwide,1 it is a degenerative disease that selectively affects the central…
- Conditions
- Multiple Sclerosis, Ataxia, Paraplegia
- Trial name
- EXO (NCT05563402)
- Testing
- Atalante
- Where
- Spain
- Volunteers
- 15 people
- Sponsor
- Multiple Sclerosis Center of Catalonia
Thumb Injury
Repair of Thumb Defect by Using the Toe Nail Flap
The thumb accounts for 50% of the total hand function. This study reports the functional outcomes and complications of people with traumatic thumb amputations who underwent toe-to-thumb reconstruction.From 2013-01 to 2018-01, 29…
- Trial name
- RTDUTNF (NCT03879941)
- Volunteers
- 29 people
- Sponsor
- Hebei Medical University
Aneurysm Aortic, Aneurysm Aortic Root
Strength Tracking From Wall Tichness Over Aortic Biomechanics (STORM)
The aim of the study is to analyse the resected portion of aneurysmatic ascending aorta in order to assess its strength to rupture, standardise the various measurements performed within the lab and try to correlate these…
- Trial name
- STORM (NCT07453251)
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- IRCCS Policlinico S. Donato