Clinical trials: Biomedical Research
Age-Related Macular Degeneration, Allergies
Tissue Repository Providing Annotated Biospecimens for Approved Investigator-directed Biomedical Research Initiatives
To collect, preserve, and/or distribute annotated biospecimens and associated medical data to institutionally approved, investigator-directed biomedical research to discover and develop new treatments, diagnostics, and…
- Conditions
- Age-Related Macular Degeneration, Allergies, Alpha-Gal Syndrome, Alzheimer Disease
- Trial name
- NCT05635266
- Testing
- Specimen sample
- Where
- United States
- Volunteers
- 20,000 people, healthy volunteers welcome
- Sponsor
- Sanguine Biosciences
COVID-19 Vaccines, Autoimmune Diseases
Effectiveness and Safety of the Inactivated COVID-19 Vaccine in Thousands of Patients With Autoimmune Diseases in China
According to the comprehensive evaluation, the completion of vaccination and the prevention and treatment strategy of integrated traditional Chinese and western medicine have obvious advantages in improving the symptoms of…
- Trial name
- NCT05831826
- Testing
- the inactivated COVID-19 vaccines
- Where
- China
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- Zhejiang Chinese Medical University
Type 2 Diabetes, Healthy (Controls)
Specimen and Data Collection in South Carolina Medicaid-Enrolled Patients With Type 2 Diabetes (T2D) and Metabolically Healthy Controls
The primary purpose of this study is to use multiomic data in combination with clinical assessments, electronic health records, cognitive and mood assessments, wearable technologies and lifestyle/behavioral data to identify data…
- Trial name
- BRISK 2 (NCT07731399)
- Testing
- Not applicable- observational study
- Where
- 2 sites in United States
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- Guardian Research Network, Inc.
Outcome Assessments (Health Care), Comprehension
Evaluation of Readability of Consent Forms on the Understanding of the Information Received by Volunteers
Prior to the completion of biomedical research, any person undergoing it must receive a readable and intelligible information about this research, in order to give free and informed consent.
- Conditions
- Outcome Assessments (Health Care), Comprehension, Language
- Trial name
- NCT03105752
- Testing
- Questionnaire of understanding
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Groupe Hospitalier Pitie-Salpetriere
Ebola Virus Disease, Marburg Virus Disease
Evaluation of Safety, Tolerability and Immune Responses of Ebola-S and Marburg Vaccines in Healthy Adults
Primary Objective: To evaluate the safety and tolerability of cAd3-EBO-S and cAd3 Marburg vaccines when administered Intramuscular (IM) at a dose of 1 x 10^11 particle units (PU) to healthy adults.
- Trial name
- NCT04723602
- Testing
- cAd3-Marburg, cAd3-EBO-S
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Albert B. Sabin Vaccine Institute
All Diagnosed Health Conditions, ADD/ADHD
At-Home Research Study for Patients With Autoimmune, Inflammatory, Genetic, Hematological, Infectious, Neurological, CNS, Oncological, Respiratory, Metabolic Conditions
We are the missing link in clinical trials, connecting patients and researchers seamlessly and conveniently using a mobile health platform to advance medical research.
- Conditions
- All Diagnosed Health Conditions, ADD/ADHD, Alopecia Areata, Ankylosing Spondylitis
- Trial name
- NCT01931644
- Where
- United States
- Volunteers
- 17,667 people, healthy volunteers welcome
- Sponsor
- Sanguine Biosciences
Cardiovascular Diseases, Cardiovascular Risk Factor
Biomedical Research Informatics Centre for Cardiovascular Sciences (The BRICCS Study)
This project will examine the diagnosis and prognosis of patients with cardiovascular disease in hospital in- and outpatients and compare their characteristics with normal controls from the community.
- Trial name
- NCT04388943
- Testing
- Observation
- Where
- United Kingdom
- Volunteers
- 9,500 people, healthy volunteers welcome
- Sponsor
- University Hospitals, Leicester
PCOS
A Clinical and Biological Research of Combined Chinese and Western Medicine in the Treatment of PCOS
This study evaluates the effects and biological mechanisms of Dingkundan，Diane-35 and the combination of Dingkundan and Diane-35 in the treatment of polycystic syndrome(PCOS) in adults women.
- Trial name
- NCT03264638
- Testing
- Dingkundan, Dingkundan & Diane-35, Diane-35
- Where
- China
- Volunteers
- 315 people, healthy volunteers welcome
- Sponsor
- Aijun Sun
Rare Diseases
A Multi-Site Leukopak Repository Providing Annotated Biospecimens for Approved Investigator-Directed Biomedical Research Initiatives
To collect, preserve, and distribute annotated leukopak biospecimens and associated medical data to institutionally approved, investigator-directed biomedical research to discover and develop new treatments, diagnostics, and…
- Trial name
- NCT05794217
- Testing
- This is a non-interventional study
- Where
- United States
- Volunteers
- 20,000 people, healthy volunteers welcome
- Sponsor
- Sanguine Biosciences
Liver-Stagnation and Spleen-Deficiency, Severe Major Depression Disorder
Effect of XingpiJieyu Formula on Mitochondrial Energy Metabolism in Severe Liver-Stagnation and Spleen-Deficiency Depression.
Study Title: Research on the therapeutic effect and clinical indicators of XingpiJieyu formula in the treatment of severe liver depression and spleen deficiency type depression based on abnormal mitochondrial energy metabolism…
- Trial name
- NCT07590609
- Testing
- XingpiJieyu Formula (XPJYF) + Escitalopram
- Where
- 2 sites in China
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Peking University Sixth Hospital
Normal Volunteers
Tissue Procurement for Biomedical Research
The need to obtain human tissue for methods development and disease correlation is frequent in Biomedical Research Center laboratories.
- Trial name
- NCT00182858
- Where
- United States
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- National Institute on Aging (NIA)
Signs and Symptoms, Fever
Biomedical Signal Extraction From Symptom Descriptions: An Observational Registry Using the OpenGenome Platform
This registry prospectively collects anonymized free-text symptom descriptions submitted voluntarily by adults through the OpenGenome platform at opengenome.bio.
- Conditions
- Signs and Symptoms, Fever, Myalgia, Skin Diseases
- Trial name
- OGNOME-REG (NCT07578610)
- Testing
- OpenGenome AI Platform
- Where
- Germany
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- OpenGenome
Tissue
De-identified Human Tissue Project
Research scientists of the University of Central Florida College of Medicine (COM) and Burnett School of Biomedical Sciences (BSBS) conduct laboratory studies in biomedical and translational medical research for the purpose of…
- Trial name
- NCT06082687
- Where
- United States
- Volunteers
- 1,000,000 people, healthy volunteers welcome
- Sponsor
- University of Central Florida
Cancer, Coronary Artery Disease
Calibration of MR and PET-MR Imaging Protocols at RIC
This is a protocol to facilitate on-site calibration of the technical aspects of the Siemens Biograph mMR (molecular MR) Positron Emission Tomography-Magnetic Resonance (PET-MR) scanner and the 3T Siemens Vida MR scanner at the…
- Trial name
- NCT02249520
- Testing
- PET-MR imaging on Biograph mMR scanner, MR-only imaging on Biograph mMR scanner, MR imaging on the Siemens Vida 3T MR scanner
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Cedars-Sinai Medical Center
Tissue Banking
Unity Cures Future (UCF) Biobank
Research scientists of the University of Central Florida College of Medicine (COM) and Burnett School of Biomedical Sciences (BSBS) conduct laboratory studies in biomedical and translational medical research for the purpose of…
- Trial name
- NCT06781411
- Where
- United States
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- University of Central Florida
Tumors, Cardiovascular Diseases
Research on the Application and Mechanism of New Biological Probes in Biomedicine
Fluorescence is one of the most commonly used research and detection techniques in the field of biomedical science. The characteristics of fluorescent probe directly affect the performance and application of fluorescence analysis…
- Conditions
- Tumors, Cardiovascular Diseases, Respiratory System Diseases, Digestive System Diseases
- Trial name
- NCT04977739
- Testing
- No intervention
- Where
- China
- Volunteers
- 737 people, healthy volunteers welcome
- Sponsor
- Nanfang Hospital, Southern Medical University
Overweight and Obesity, Exercise
Establishment of the 2H-labeling Protocol at Pennington Biomedical Research Center
A method has been developed to measure in vivo adipose kinetics and turnover rates, which is a substantive departure from previous indirect and in vitro approaches.
- Trial name
- NCT03530111
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Pennington Biomedical Research Center
Artificial Intelligence, Biomedical Research
Attitudes and Perceptions of Corresponding Authors From Top International Medical Journals Regarding the Use of Artificial Intelligence in the Scientific Process
"Artificial intelligence (AI), including large language models and conversational tools, is increasingly being used in medical research.
- Conditions
- Artificial Intelligence, Biomedical Research, Scientific Publishing, Surveys and Questionnaires
- Trial name
- AISurvey6 A+ (NCT07326501)
- Testing
- observational survey
- Where
- France
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Nice
Healthy
Blood Collection for COM/BSBS
The objective of this biospecimen collection protocol is the acquisition of blood from adult volunteers. These biospecimens will be transferred to the College of Medicine (COM)/Burnett School of Biomedical Sciences (BSBS)…
- Trial name
- NCT06082661
- Where
- United States
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- University of Central Florida
Human Immunodeficiency Virus (HIV)
Phase II Safety and Acceptability of an Investigational Injectable Product, TMC278LA, for Pre-Exposure Prophylaxis
This is a multi-site, double-blinded, two-arm, two:one, randomized, trial comparing the safety of an intramuscular (IM) injection of TMC278 LA to a placebo given once every eight weeks over a 40 week period among sexually active…
- Trial name
- TMC278LA (NCT02165202)
- Testing
- Rilpivirine
- Where
- 4 sites in United States, South Africa and 1 more
- Volunteers
- 136 people, healthy volunteers welcome
- Sponsor
- PATH