Clinical trials: Biopsy, Fine-Needle
Breast Cancer
RPFNA Assessment of Exercise Effect in Breast Cancer
This study is being done to see if the investigators can measure changes that occur in breast tissue when women at risk of developing breast cancer start an exercise program.
- Trial name
- NCT01961128
- Testing
- Exercise Intervention
- Where
- United States
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Dana-Farber Cancer Institute
Solid Pancreatic Masses
Endoscopic Ultrasound-guided Fine Needle Biopsy With 25-gauge Biopsy Needles for Solid Pancreatic Masses
For 12 months after approvement by the University of Yonsei institutional review board, of the 59 patients older than 20 years referred to our medical center for EUS-FNA or FNB, all consecutive pancreatic lesions were evaluated…
- Trial name
- NCT01795066
- Testing
- EUS-FNB with 25-gauge (Echotip ProCore; Cook Endoscopy Inc, Limerick, Ireland)
- Where
- South Korea
- Volunteers
- 56 people
- Sponsor
- Yonsei University
Post-ERCP Acute Pancreatitis
Rectal Indomethacin to Prevent Post-Endoscopic Retrograde Cholangiopancreatography (ERCP) Pancreatitis
The purpose of this study is to assess whether peri-procedural administration of rectal indomethacin, compared to placebo, can reduce the incidence of post-ERCP pancreatitis.
- Trial name
- NCT01774604
- Testing
- Indomethacin
- Where
- United States
- Volunteers
- 449 people
- Sponsor
- Dartmouth-Hitchcock Medical Center
Biopsy, Fine-needle, Pancreatic Neoplasm
EUS-FNB With ROSE Vs. EUS-FNB Without ROSE
Rationale: Rapid on-Site Evaluation (ROSE) of cytologic specimens acquired with EUS-guided fine needle aspiration (EUS-FNA) represents the most accurate available technique to reach a definitive diagnosis in patients with…
- Trial name
- FROSENOR (NCT03322592)
- Testing
- Rapid on-site evaluation (ROSE), Histologic evaluation
- Where
- 13 sites in United States, Australia and 6 more
- Volunteers
- 800 people
- Sponsor
- Azienda Ospedaliera Universitaria Integrata Verona
Anxiety, Pancreatic Cancer
Graphic Novel for Patients Undergoing EUS-FNB
Endoscopy with endoscopic ultrasound (EUS) is a primary technique for diagnosing and treating severe pancreatic disorders. However, the procedure can cause fear and anxiety in patients, especially when a biopsy is involved.
- Conditions
- Anxiety, Pancreatic Cancer, Pancreatic Cystic Lesions, Stress
- Trial name
- NCT06268106
- Testing
- Graphic novel visualization
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- The Mediterranean Institute for Transplantation and Advanced Specialized Therapies
Endoscopic Ultrasonography, EUS-FNA
Heparin-based Wet Suction Method in EUS Fine Needle Biopsy of Solid Pancreatic Mass
The objective of this randomized cross-over trial is to evaluate whether Heparin based wet suction technique, compared with dry suction technique, shall present a higher quality tissue core by using quantitative macroscopic and…
- Conditions
- Endoscopic Ultrasonography, EUS-FNA, Pancreatic Neoplasms
- Trial name
- NCT04707560
- Testing
- EUS fine needle biopsy with heparin wet suction
- Where
- Taiwan
- Volunteers
- 50 people
- Sponsor
- National Cheng-Kung University Hospital
Breast Cancer
An Examination of Predictors of Indicators of Response to Letrozole 2.5 mg
To assess the quantitative real time PCR results of oligonucleotide probes for a number of gene transcription products that may be useful as predictors or indicators of response to letrozole
- Trial name
- NCT00291109
- Testing
- letrozole 2.5 mg
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Kansas
Lung Cancer
Computed Tomography (CT) Guided Lung Biopsy: Core or Fine Needle Aspiration
This study is a comparison of core needle biopsy with fine needle aspiration biopsy in the evaluation of lung nodules.
- Trial name
- NCT00188526
- Testing
- lung biopsy
- Where
- Canada
- Sponsor
- University Health Network, Toronto
Endoscopic Ultrasonography-guided Fine Needle Aspiration
EUS-FNA for Patients Taking Anticoagulants Without Heparin Bridge
To evaluate the feasibility of EUS-FNA for patients taking anticoagulants without heparin bridge.
- Trial name
- NCT02977650
- Testing
- Endoscopic ultrasonography-guided fine needle aspiration
- Where
- Japan
- Volunteers
- 150 people
- Sponsor
- Hokkaido Pancreatobiliary Endoscopic Intervention Study Group
Diagnoses Diseases, Ultrasound Therapy; Complications
19 Versus 22-Gauge Needle for EUS-LB
Chronic liver disorders (CLD) are a major cause of morbidity and mortality for individuals in the US. Though serologic analysis will often lead to a conclusive diagnosis, liver biopsy remains an important method for helping to…
- Conditions
- Diagnoses Diseases, Ultrasound Therapy; Complications, Liver Diseases
- Trial name
- EUSLB1922 (NCT02967991)
- Testing
- EUS-guided liver biopsy
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Geisinger Clinic
Pancreatic Solid Lesions
The Comparison of Wet Suction and Dry Suction Technique in EUS-FNA for the Outcomes in Pancreatic Solid Lesions
The objective of this randomized controlled trial is to evaluate whether wet suction technique (WST), compared with dry suction technique (DST), shall present a better outcome with regard to the diagnostic yield and specimen…
- Trial name
- NCT03821974
- Testing
- wet suction technique, dry suction technique
- Where
- China
- Volunteers
- 50 people
- Sponsor
- The Third Xiangya Hospital of Central South University
Neuroendocrine Tumors
Nonfunctioning Small (≤2 cm) Neuroendocrine Pancreatic Incidentaloma
Neuroendocrine tumors (NETs) and carcinomas account for 10-15 % of all pancreatic incidentalomas. The management of pancreatic NETs depends on tumor stage and on presence or not of hormonal syndrome.
- Trial name
- NCT03022188
- Where
- 22 sites in Belgium, France
- Volunteers
- 100 people
- Sponsor
- Société Française d'Endoscopie Digestive
Prostate Cancer
Interstitial Assessment of Architectural Heterogeneity in Prostate Cancer Using a Fine Needle Photoacoustic Probe
In this project, we will integrate the Photoacoustic (PA) technology into a prostate biopsy procedure through a fine needle probe.
- Trial name
- NCT05965180
- Testing
- Fine Needle Photoacoustic Probe
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Michigan Rogel Cancer Center
Medullary Thyroid Carcinoma, Nodular Goiter
Calcitonin in Needle Wash Using Electrochemiluminescence Method For Diagnosis Of Medullary Thyroid Carcinoma.
Medullary thyroid carcinoma (MTC) is a tumor originating from parafollicular C cells of the thyroid. (1) Representing 1 to 7% of all thyroid carcinoma cases (2, 3, 4).
- Trial name
- NCT06067594
- Testing
- Fine Needle Aspiration Cytology (FNAC) procedure+calcitonin measurement
- Where
- Argentina
- Volunteers
- 155 people
- Sponsor
- Austral University, Argentina
Pancreas Adenocarcinoma
Establishment of Pancreas Cancer and Cancer-associated Fibroblast Using EUS-guided Biopsy Samples
Organoid has emerged as the novel platform for preclinical anticancer drug testing in pancreatic ductal adenocarcinoma (PDA). However, most organoid models are not reconstituted with a tumor microenvironment.
- Trial name
- NCT05571956
- Testing
- Pancreatic ductal adenocarcinoma organoids and cancer-associated fibroblasts establishment group
- Where
- South Korea
- Volunteers
- 50 people
- Sponsor
- Ajou University School of Medicine
Pancreatic Mass on Imaging
Yield of Endoscopic Ultrasound Guided Fine Needle Aspiration (EUS-FNA) With and Without the Use of a Stylet in the Biopsy Needle
Purpose: To compare the diagnostic yield of endoscopic ultrasound guided fine needle aspiration biopsy (EUS-FNA) in patient with pancreatic masses with and without the use of a stylet in place within the biopsy needle.
- Trial name
- NCT01241799
- Testing
- Endoscopic ultrasound guided fine needle aspiration biopsy, Stylet out FNA first, Stylet in FNA second
- Where
- Canada
- Volunteers
- 72 people
- Sponsor
- University of British Columbia
Thyroid Nodule, Thyroid Cancer
Clinical Validation of a Molecular Signature to Detect Cancer in Thyroid Nodules With Indeterminate Cytology
1. Principal objective: The primary objective of this study is to validate the diagnostic performance of a Dx15 molecular test based on molecular transcriptomic signatures previously identified in distincts cohorts of samples to…
- Trial name
- CITHY (NCT02225509)
- Testing
- FNA biopsy for thyroid nodule(s)
- Where
- France
- Volunteers
- 1,000 people
- Sponsor
- Diaxonhit
Pancreatic Tumors
Standard Versus Fanning Techniques for Endoscopic Ultrasound-Fine Needle Aspiration (EUS-FNA)
Endoscopic Ultrasound (EUS)-guided biopsy is the most ideal technique for evaluating a growth in the pancreas. EUS-guided biopsies yield a definitive diagnosis in greater than 80% of cases.
- Trial name
- NCT01501903
- Testing
- Standard, Fanning
- Where
- United States
- Volunteers
- 52 people
- Sponsor
- Shyam Varadarajulu
Focus: Breast Cancer With Axillary Node Metastasis
Ultrasound Guided Core Biopsy vs Fine Needle Aspiration for Evaluation of Axillary Lymphadenopathy
The study was performed to determine if either ultrasound guided core biopsy or fine needle aspiration of an axillary lymph node has superior sensitivity in detecting metastatic carcinoma from the ipsilateral breast.
- Trial name
- NCT01920139
- Testing
- Fine needle aspiration and core biopsy of lymph node, Axillary surgery, Titanium marker
- Where
- United States
- Volunteers
- 105 people
- Sponsor
- University of Pittsburgh
Pancreatic Tumor
Evaluation of EUS-Guided 22 Gauge Core Biopsy Versus Fine-needle Aspiration for Suspected Pancreatic Neoplasms
We aim to compare the efficacy (diagnostic yield), ease of use, and technical success rates of EUS guided 22 gauge fine needle aspiration to core biopsy in the evaluation of pancreatic tumors.
- Trial name
- NCT01673334
- Testing
- Fine Needle Aspiration (FNA) and Core biopsy (FNB)
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Virginia