Clinical trials: Biopsy, Fine-Needle
Pancreas Cancer
Conventional Versus Elastography Targeted Endoscopic Ultrasound Fine Needle Aspiration of Solid Pancreatic Lesions
Diagnostic assessment of solid pancreatic lesions may represent a real challenge in the clinical practice, even with the aid of tissue sampling by means of endoscopic ultrasound (EUS) fine needle aspiration (FNA).
- Trial name
- NCT03210948
- Testing
- RTE-guided EUS-FNA, Conventional EUS-FNA
- Where
- Italy
- Volunteers
- 142 people
- Sponsor
- Ospedali Riuniti di Foggia
Thyroid Cancer
Predictive Factors of Clinical, Laboratory and Imaging Findings Routinely Used in Diagnosing Thyroid Cancer
The purpose of this study is to describe the correlation between the cytohistology exam of patients undergoing thyroid surgery, and the predictive values of: suspicious clinical findings, preoperative thyroid imaging, and the…
- Trial name
- TIR-2009-01 (NCT01074684)
- Where
- 8 sites in Italy
- Volunteers
- 959 people
- Sponsor
- National Cancer Institute, Naples
Cancer, Thyroid
Use of an In Vivo Optical Probe to Discriminate Benign From Malignant Thyroid Nodules
This study will investigate the usefulness of an optical probe in the differentiation of thyroid cancer from normal thyroid tissue in a thyroidectomy specimen.
- Trial name
- NCT01401855
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Boston Medical Center
PANCREATIC CANCER
Diagnostic Accuracy of FNA: is Aspiration- Related?
BACKGROUND: EUS-FNA has a central role in the diagnostic algorithm of solid pancreatic masses. Different needle diameters and the use of stylet are not associated with differences in terms of diagnostic yield for malignancy.
- Trial name
- expect fna (NCT01717196)
- Testing
- different volume aspiration
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- The Mediterranean Institute for Transplantation and Advanced Specialized Therapies
Pancreatic Cystic Lesion
Antibiotic Prophylaxis for Endoscopic Ultrasound Guided Fine Needle Aspiration of Pancreatic Cystic Lesions
The purpose of this study is to determine whether the use of antibiotic prophylaxis is appropriate when performing a pancreatic cyst fine needle aspiration guided by endoscopic ultrasonography.
- Trial name
- NCT02261896
- Testing
- Ciprofloxacin
- Where
- Spain
- Volunteers
- 226 people
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
The Malignant Lesions and Non-malignant Lesions of Pancreas, Bile Duct, Liver and Lymph Node
An Artificial Intelligence System for ROSE of EUS-FNA Sample: a Prospective, Multicenter, Diagnostic Study.
This is an observational study with a prospective, multicenter, disgnostic design. An artificial intelligence system named ROSE-AI system was developed using cytopathological slide images taken by microscope camera or smartphone…
- Trial name
- ROSE，EUS-FNA (NCT06718725)
- Testing
- ROSE-AI system
- Where
- China
- Volunteers
- 236 people, healthy volunteers welcome
- Sponsor
- Qilu Hospital of Shandong University
Pancreatic Cancer, Neuroendocrine Tumors
A Clinical Trial With a New Needle Device Comparing Two Needles for EUS_FNA of Solid Lesions.
Endoscopic ultrasound-guided fine-needle aspiration biopsy (EUS-FNA) is a reliable, safe, and effective technique for obtaining samples from the GI wall lesions and from organs adjacent to the GI tract (pancreas…
- Conditions
- Pancreatic Cancer, Neuroendocrine Tumors, Lymphadenopathies, GIST
- Trial name
- EUS-FNA (NCT02246322)
- Testing
- 25G needle, 22G needle
- Where
- Italy
- Volunteers
- 144 people
- Sponsor
- Istituto Clinico Humanitas
Biopsy, Fine-Needle
Comparison of DNA Ploidy and Conventional Cytology
150 patients who had suspected pancreatic malignancy were planed to be enrolled in this study. Equal cytological samples of each patient undergoing EUS-FNA were examined by digital image analysis and conventional cytology…
- Trial name
- NCT02921100
- Testing
- cytology, DNA ploidy, EUS-FNA
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Changhai Hospital
Thyroid Nodule
Clinical Study of Ultrasonic Artificial Intelligence and Fine Needle Aspiration in Qualitative Diagnosis of Thyroid Nodules
To study the value of thyroid artificial intelligence diagnosis system and fine needle puncture in the diagnosis of benign and malignant thyroid nodules, so as to provide evidence-based medical evidence for the diagnosis of…
- Trial name
- NCT05407506
- Testing
- THYROID AI
- Volunteers
- 1,000 people
- Sponsor
- Luo Dingcun
Colorectal Cancer, Breast Cancer
Feasibility Study of Genomic Profiling Methods and Timing in Tumor Samples
This is a feasibility study to look for genetic alterations in tissue and blood samples that may be useful in determining what treatments may be useful in the patient's cancer care.
- Conditions
- Colorectal Cancer, Breast Cancer, Gynecological Cancer, Metastatic
- Trial name
- NCT01703585
- Where
- Canada
- Volunteers
- 45 people
- Sponsor
- University Health Network, Toronto
Diagnostic Self Evaluation
Diagnostic Efficiency of Touch Imprints Versus Smears
Cytopathologists work along with radiologist in the diagnosis of lesions. Rapid on site interpretation (ROSE) of fine needle aspiration (FNA) smears of radiologically suspicious lesions is a common clinical practice.
- Trial name
- NCT03224910
- Testing
- Cytologic techniques used for rapid on site interpretation
- Where
- United States
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- University of Mississippi Medical Center
Tumor Sampling
Investigation to Evaluate Safety and Efficacy of the Endodrill Model X Biopsy Instrument
This is an investigator led prospective open label investigation, performed at three clinics in Sweden, comparing the flexible endoscopic biopsy instrument Endodrill Model X with the standard sampling method endoscopic ultrasound…
- Trial name
- NCT04519138
- Testing
- Endodrill Model X, Fine-needle aspiration/biopsy
- Where
- 3 sites in Sweden
- Volunteers
- 7 people
- Sponsor
- Region Skane
Breast Cancer
Protocol for Postmenopausal Women at Increased Risk of Developing Breast Cancer
A study to examine the potential associations between common single nucleotide polymorphisms and pre-cancerous conditions in breast tissue specimens from postmenopausal women.
- Trial name
- NCT00329017
- Testing
- Fine needle aspiration
- Where
- United States
- Sponsor
- Carol Fabian, MD
Virtual Reality Therapy, Ultrasound
The Effect of Virtual Reality Applications
Thyroid nodules are a common health problem in the adult population. Ultrasound-guided fine-needle aspiration biopsy (FNAB) is the standard diagnostic procedure for evaluating suspected thyroid nodules.
- Conditions
- Virtual Reality Therapy, Ultrasound, Fine Needle Aspiration Biopsy, Thyroid Nodule (Diagnosis)
- Trial name
- NCT06792929
- Testing
- Virtual reality headset
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Dicle University
Hepatocellular Carcinoma
Primary Culture of Residual Specimens Obtained From Aspiration of Hepatic Tumor to Predict the Prognosis of the Patients
The aim of this project is to investigate whether the proliferative speeds of cultured cells using our method can be integrated into Barcelona Clinic Liver Cancer (BCLC) staging classification for the possibility of personalized…
- Trial name
- NCT02587793
- Testing
- not interventional study
- Where
- 2 sites in Taiwan
- Volunteers
- 208 people
- Sponsor
- Kaohsiung Medical University Chung-Ho Memorial Hospital
Pancreatitis
Serum Parameter Prior and After EUS-guided Fine Needle Aspiration of the Pancreas
Endoscopic ultrasonography (EUS ) -guided fine needle aspiration (EUS -FNA ) of focal pancreatic lesions is an essential diagnostic procedure with high therapeutic effect in clinical routine.
- Trial name
- NCT02397993
- Testing
- blood collection, fine needle aspiration
- Where
- 3 sites in Germany
- Volunteers
- 208 people
- Sponsor
- Helios Albert-Schweitzer-Klinik Northeim
Healthy, Male Infertility
HOP-2A - Intratesticular Hormone Levels
The purpose of this investigational study is to find out what hormones are present in healthy male testicles using fine needle aspiration.
- Conditions
- Healthy, Male Infertility, Prostate Disease
- Trial name
- HOP-2A (NCT00756561)
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Washington
Hurthle Cell Thyroid Cancer, Tall Cell Variant Thyroid Cancer
Studies on Tumors of the Thyroid
Participants in this study will be patients diagnosed with or suspected to have a thyroid nodule or thyroid cancer. The main purpose of this study is to further understand the methods for the diagnosis and treatment of thyroid…
- Conditions
- Hurthle Cell Thyroid Cancer, Tall Cell Variant Thyroid Cancer, Follicular Thyroid Cancer, Thyroid Cancer
- Trial name
- NCT00001160
- Testing
- 68-Gallium Dotatate
- Where
- United States
- Volunteers
- 2,500 people
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Pancreatic Neoplasms
Fine Needle Biopsy of Solid Pancreatic Mass Lesions
This is a randomized trial to evaluate and directly compare the tissue quality, diagnostic sucess and safety profile of four different Fine Needle Biopsy needles.
- Trial name
- NCT04085055
- Testing
- Solid pancreatic mass lesion biopsy
- Where
- United States
- Volunteers
- 130 people
- Sponsor
- AdventHealth
Nodular Goiter, Thyroid Cancer
Elastography in Thyroid Nodules
Nodular goiter is a highly prevalent disease in iodine-deficient areas. Usually nodule assessment includes ultrasonography (US) and fine-needle aspiration (FNA), but some benign nodules can hardly be distinguished from…
- Trial name
- NCT01102127
- Testing
- Elastography
- Where
- Spain
- Volunteers
- 128 people
- Sponsor
- Castilla-León Health Service