Clinical trials: Biopsy, Fine-Needle
Biopsy, Fine-needle, Pancreatic Neoplasm
EUS-FNB for Solid Pancreatic Lesions: Side-fenestrated Vs Fork-tip Needle
Rationale: Until now there are no prospective studies comparing the 22 gauge and 25 gauge side-fenestrated and fork-tip needles.
- Trial name
- NCT03622229
- Testing
- Histologic evaluation
- Where
- 2 sites in Italy
- Volunteers
- 192 people
- Sponsor
- Azienda Ospedaliera Universitaria Integrata Verona
Lung Cancer
Endobronchial Ultrasound Versus Mediastinoscopy in Patients With Non-Small Cell Lung Cancer (NSCLC)
The goal of this clinical research study is to compare 2 different methods for checking lymph glands (in the middle of the chest) for cancer cells.
- Trial name
- NCT00559611
- Testing
- Endobronchial Ultrasound, Mediastinoscopy
- Where
- United States
- Volunteers
- 53 people
- Sponsor
- M.D. Anderson Cancer Center
Satisfaction, Personal
3D Thyroid Education Model for Student
The purpose of our study is to develop a high-fidelity thyroid education model, that can be utilized for medical students/ PGY doctors/ residents training.
- Trial name
- NCT06147011
- Testing
- 3D printed educational model
- Where
- Taiwan
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Fu Jen Catholic University
Pancreatic Neoplasm
EUS-FNA of Solid Pancreatic Mass: Comparison Between Negative Pressure and Slow-pull Technique
50 patients with pancreatic mass will undergo endoscopic ultrasound-guided fine needle aspiration using two techniques: negative pressure and slow-pull. Cytological results will be compared.
- Trial name
- EUS-FNA (NCT03111368)
- Testing
- Endoscopic ultrasound-guided fine needle aspiration
- Where
- Brazil
- Volunteers
- 1 people
- Sponsor
- University of Sao Paulo General Hospital
Chronic Hepatitis C
Evaluation of Hepatic Pharmacokinetics for Grazoprevir (MK-5172) in Participants With Chronic Hepatitis C (MK-5172-022)
This study is divided into 2 segments, and proposes to qualify fine needle aspiration (FNA) as a platform to evaluate the hepatic pharmacokinetics of low and high oral doses of Grazoprevir (MK-5172) in non-cirrhotic participants…
- Trial name
- NCT01547312
- Testing
- Peg-Interferon, Liver Samples from FNA, Liver Samples from CNB
- Sponsor
- Merck Sharp & Dohme LLC
Pancreatic Cancer
Evaluating the Number of Passes Required for Diagnostic Cell Block During EUS-FNA of Solid Pancreatic Mass Lesions
This study will test the amount of tissue, called "cell block", obtained from your pancreas. Patients who are asked to participate in this study have a growth (mass) in the pancreas that needs a biopsy so a diagnosis can be made.
- Trial name
- NCT01809028
- Testing
- EUS FNA with 2 passes, EUS FNA with 4 passes
- Where
- United States
- Volunteers
- 62 people
- Sponsor
- AdventHealth
Thyroid Neoplasms
Pyrosequencing of the BRAFV600E Mutation
To investigate the diagnostic efficiency of pyrosequencing for the mutant BRAF allele in ultrasound (US)-guided fine needle aspiration biopsies (FNAB) of thyroid incidentalomas.
- Trial name
- NCT00551486
- Testing
- ultrasound-guided fine needle aspiration biopsy
- Where
- South Korea
- Volunteers
- 101 people
- Sponsor
- Chungnam National University
Mediastinum
EBUS-TBNA vs EUS-B-FNA for Needle Aspiration of Mediastinal Lesions
Endobronchial Ultrasound Guided Transbronchial Needle aspiration (EBUS-TBNA) is a firmly established modality for diagnostic evaluation of mediastinal lesions.
- Trial name
- TEAM (NCT02704078)
- Testing
- EBUS-TBNA, EUS-B-FNA
- Where
- India
- Volunteers
- 100 people
- Sponsor
- All India Institute of Medical Sciences
Biopsy, Fine-Needle, Endosonography
Impact of Suction in the EUS-guided Fine Needle Biopsy of Solid Pancreatic Lesions
Tissue acquisition by Endoscopic Ultrasound (EUS) has become a modality of diagnosis and clinical orientation for several diseases.
- Conditions
- Biopsy, Fine-Needle, Endosonography, Pancreatic Neoplasm
- Trial name
- NCT04164017
- Testing
- EUS-guided FNB with Syringe Suction, EUS-guided FNB without Syringe Suction
- Where
- Portugal
- Volunteers
- 100 people
- Sponsor
- Centro Hospitalar De São João, E.P.E.
Thyroid Cancer, Thyroid Nodule
The Ultracyt Study - is EU-TIRADS Useful in Selecting Nodules for Fine Needle Aspiration Cytology?
This is a randomized study evaluating selective fine-needle aspiration cytology based on structured ultrasound using EU-TIRADS versus non-selective ultrasound guided cytology.
- Trial name
- Ultracyt (NCT05583097)
- Testing
- Non-selective cytology
- Where
- Sweden
- Volunteers
- 195 people
- Sponsor
- Vastra Gotaland Region
Pancreatic Neoplasms
Discovery of Soluble Biomarkers for Pancreatic Cancer Using Innovative All-Patient Inclusive Methodology
Pancreatic ductal adenocarcinoma (PDAC) remains among cancers with a very poor prognosis (1-year survival <20%). Endoscopic ultrasound with fine needle aspiration (EUS/FNA) is the common examination for all patients with…
- Trial name
- PanEXPEL2 (NCT04370574)
- Testing
- Soluble Biomarkers dosage
- Where
- France
- Volunteers
- 200 people
- Sponsor
- University Hospital, Montpellier
Pancreatic Masses
RCT Comparing Accuracy Among Franseen, Forward-bevel Westcott, and Fork-tip EUS-FNB Needle in Diagnosis of Solid Pancreatic Lesions
Endoscopic Ultrasound-Guided Fine Needle Aspiration (EUS-FNA) is a well-established technique for pancreatic tissue acquisition, offering a high diagnostic accuracy ranging from 78% to 95%, along with a favorable safety profile.
- Trial name
- NCT07032974
- Testing
- Franseen, Forward-bevel, Fork-tip
- Where
- Thailand
- Volunteers
- 108 people
- Sponsor
- Mahidol University
Intraocular Melanoma
Study of Tumor Samples in Patients Undergoing Radiation Therapy or Surgery For Primary Melanoma of the Eye
RATIONALE: Studying samples of tumor tissue from patients with cancer in the laboratory may help doctors learn more about changes that occur in DNA and identify biomarkers related to cancer.
- Trial name
- NCT00952939
- Testing
- fluorescence in situ hybridization, laboratory biomarker analysis, fine-needle aspiration
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Case Comprehensive Cancer Center
Endometrial Hyperplasia
Comparison of Dilatation & Curettage and Endometrial Aspiration Biopsy Accuracy in Patients Treated With Progestin for Endometrial Hyperplasia: A Korean Gynecologic Oncology Group Study
A prospective multicenter trial has been started in Korea to evaluate the diagnostic accuracy of endometrial aspiration biopsy compared with D\&C in patients treated with progestin for endometrial hyperplasia (EH).
- Trial name
- NCT02412072
- Where
- South Korea
- Volunteers
- 75 people
- Sponsor
- Korean Gynecologic Oncology Group
Inflammatory Myopathy
Renal Manifestations During Idiopathic Inflammatory Myopathies
There are currently no recommendations regarding treatments for Idiopathic Inflammatory Myopathies (IIM) due to the difficulty in conducting high-powered randomized controlled trials.
- Trial name
- IIM (NCT06904937)
- Where
- France
- Volunteers
- 15 people
- Sponsor
- University Hospital, Strasbourg, France
Pancreatic Cyst
Evaluation of Pancreatic Cystic Lesions Via EUS-guided Fine Needle Aspiration With and Without Micro Forceps Biopsies
Pancreatic cystic lesions (PCLs) are a common incidental finding in cross sectional imaging (up to 27% on CT scan and 41% on MRI) and pose a management challenge to physicians.
- Trial name
- NCT04404101
- Testing
- 1). EUS-FNA plus MFB, 2). EUS-FNA Alone
- Where
- 3 sites in United States
- Volunteers
- 300 people
- Sponsor
- University of Colorado, Denver
Gastrointestinal Subepithelial Tumors
EUS-guided Fine Needle Aspiration (EUS-FNA) Versus EUS-guided Fine Needle Biopsy (EUS-FNB) for Diagnosis of Subepithelial Tumors
Background: Preoperative pathologic diagnosis of subepithelial tumor (SET) can improve clinical decision making. Although EUS-guided fine needle aspiration (FNA) is currently considered the standard method for sampling SET, its…
- Trial name
- NCT02943837
- Testing
- Device: 22G FNA needle, Device: 20G FNB needle
- Sponsor
- Asan Medical Center
Adenocarcinoma, Carcinoma
Anatomical-Clinical Base of Adenocarcinoma Pancreatic
BACAP-2 is a prospective biobank dedicated to the pancreatic adenocarcinoma including clinical data and biological samples from tumor.
- Conditions
- Adenocarcinoma, Carcinoma, Neoplasms
- Trial name
- BACAP-2 (NCT06128343)
- Testing
- collection of biological samples
- Where
- 8 sites in France
- Volunteers
- 1,500 people
- Sponsor
- University Hospital, Toulouse
Immunocompromised
Diagnosis of Invasive Pulmonary Aspergillosis by Direct Lung Tissue Aspergillus Galactomannan Antigen Detection From Aspirate by Ultrasound-guided Fine Needle Aspiration
Invasive aspergillosis is a serious and often fatal infection in patients who are neutropenic or have undergone solid organ or stem cell transplantation. However, early diagnosis of invasive aspergillosis is a challenge.
- Trial name
- NCT01301755
- Testing
- Lung aspiration
- Where
- Taiwan
- Volunteers
- 50 people
- Sponsor
- National Taiwan University Hospital
Breast Cancer
Protocol for Women at Increased Risk of Developing Breast Cancer
A pilot study to assess the effects of six months of letrozole on breast tissue risk markers in postmenopausal women on hormone replacement therapy at high risk of developing breast cancer.
- Trial name
- NCT00291135
- Testing
- letrozole
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- Carol Fabian, MD